LOCUS       NM_053538               2170 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus lysosomal protein transmembrane 5 (Laptm5), mRNA.
ACCESSION   NM_053538
VERSION     NM_053538.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2170)
  AUTHORS   Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S
            and Russo T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   2  (bases 1 to 2170)
  AUTHORS   Origasa M, Tanaka S, Suzuki K, Tone S, Lim B and Koike T.
  TITLE     Activation of a novel microglial gene encoding a lysosomal membrane
            protein in response to neuronal apoptosis
  JOURNAL   Brain Res Mol Brain Res 88 (1-2), 1-13 (2001)
   PUBMED   11295227
REFERENCE   3  (bases 1 to 2170)
  AUTHORS   Adra CN, Zhu S, Ko JL, Guillemot JC, Cuervo AM, Kobayashi H,
            Horiuchi T, Lelias JM, Rowley JD and Lim B.
  TITLE     LAPTM5: a novel lysosomal-associated multispanning membrane protein
            preferentially expressed in hematopoietic cells
  JOURNAL   Genomics 35 (2), 328-337 (1996)
   PUBMED   8661146
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC060517.1.
            
            On Dec 20, 2003 this sequence version replaced NM_053538.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC060517.1, FQ225663.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2170
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2170
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /note="lysosomal protein transmembrane 5"
                     /db_xref="GeneID:89783"
                     /db_xref="RGD:621838"
     exon            1..94
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..793
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /note="lysosomal multispanning membrane protein 5; granule
                     cell death-10; lysosomal-associated protein transmembrane
                     5"
                     /codon_start=1
                     /product="lysosomal-associated transmembrane protein 5"
                     /protein_id="NP_445990.2"
                     /db_xref="GeneID:89783"
                     /db_xref="RGD:621838"
                     /translation="MASRAVPVRQTCCCFNVRVATVALAIYHIVMSVLLFIEHVVEVA
                     RGKVSCRFSKMPYLRLADLLSSFLLIGVLFIISLSLLFGVVKNREKYLIPFLSLQIMD
                     FLLCLLTLLGSYIELPAYLKFARPRPGPSKVPLMTLQLLDFCLSILTLCSSYMEVPTY
                     LNFKSMNHMNYLPSQEGMPRSQFINMMLIFSVAFITVLILKVYMFKCVWTCYRFMKHM
                     NSAVEDSSSKLFLKVALPSYEEALSLPTKTPEGDLAPPPYSEV"
     exon            95..188
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     exon            189..265
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     exon            266..391
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     exon            392..514
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     exon            515..610
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     exon            611..703
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
     exon            704..2072
                     /gene="Laptm5"
                     /gene_synonym="gcd-10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcaccatg gcctcccgtg cagtgccagt caggcagaca tgctgttgtt tcaatgtccg
       61 agttgccacc gtagccctgg ccatctacca tatagtcatg agcgtcttgc tgttcattga
      121 gcatgtggtg gaggtggccc gcggtaaagt ctcctgcagg ttctccaaga tgccatacct
      181 caggctggct gacctgctct ccagcttcct gctcatcgga gtcctcttca ttatcagcct
      241 cagcctgctg ttcggagtgg tcaagaaccg ggagaagtac ctgataccct tcctgtccct
      301 tcaaatcatg gacttcctgc tgtgcctgct cacactgttg ggctcctaca tcgaattacc
      361 agcatacctg aagtttgccc ggccccggcc cggtccttct aaggtaccct tgatgacact
      421 gcagctgctg gacttctgtt tgagcatcct gaccctgtgc agctcctata tggaagtgcc
      481 cacctacctt aacttcaagt ccatgaacca catgaattac ctgccgagtc aggagggcat
      541 gccacgcagc cagttcatca acatgatgct catcttttca gtggccttta tcaccgtgct
      601 catcctgaag gtctacatgt tcaagtgtgt ttggacatgc tacagattca tgaagcacat
      661 gaattcggcc gtggaggaca gcagttccaa gctgttccta aaggtggctc tgccgtccta
      721 tgaggaagcc ttgtctctgc ccactaagac tccagagggg gaccttgcac cacccccata
      781 ctcggaagtg tgattcccac caggctttca gcccttgggc tgggagaggc ggaactcccc
      841 gcctcctgct tcttcacttt gatggctgcc atggcctact acaggacagt ctgcttgtgc
      901 accccccctc actgtcctct ctgcttgggg acctcttact cacaacagag tcaccctggg
      961 ctaaatgacc ctttgaagct cagagtactc agcctagcat ctcatctagt cttcatcagc
     1021 aatgatactt gttcagagaa cagtcgtggc aaattagggg gagtttggtt aacaactact
     1081 ggcttgatct gtttagctag atagccaaca ccagcagggg cagcaggaag agaatctggc
     1141 caagcaacaa ttcctggtgt cagtccatac tcagctgtca tgggtcgtgg gtcatgggtc
     1201 atgggtcatg gatcatgggt catgatcatg gtgcccattt gctaccccca agtacccaaa
     1261 agtgtacaaa taaaacaata ccttcaaatg cgttgcttaa acaaatacca atccagccaa
     1321 ccgctgtcat taggcattat gagaaaatct aataagaaaa tgaggtgtca aacgggaggg
     1381 aaagaaaaag aaatgaaggt cctcccacca ttcactgtag ggcacaccat ggacaccctg
     1441 cccagcctct gcttgagttt ctctagcatc tggaggctgg gaagtccaac agtcctgcaa
     1501 ctgccctgaa cgttctgctc agcatggaaa aaaaaagttg ctcccgtttt aaacaatcct
     1561 tcccatgagt caccgctctg aggcaagctg tccttatctt cagtcaagtg ttccccatag
     1621 ccacacaatg gggaggttcc tgccagggtc actttagcca ctggcggatt taaggtctgg
     1681 ttatcaccat gacatcccaa cagccaggtt gttccagcct gtttgctcag ggctacgctc
     1741 agggggtggc aggcttggaa ttggctgccc tgtgggcagt tgtctgtcac tatgtctgtc
     1801 actatggctg cctagttggg ggcaggctag cccatggggt gtgaagagcc agccagagtc
     1861 ttgtgtccca tggtggcagc aaggagggtc agtccaggtg tctctgccca ctttcccatt
     1921 gctcggggtt ctaggggttg ctaggaattt gctcctgctt gtggtgtaga tggggctaca
     1981 gggctgagag ggccgagaga tgttcccact gtgcctgtgt cattgcttgt gtgtgacttg
     2041 gaagaagggc caataaaaca gctgcaagct ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2161 aaaaaaaaaa
//
