LOCUS       NM_001106462             879 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus late endosomal/lysosomal adaptor, MAPK and MTOR
            activator 5 (Lamtor5), mRNA.
ACCESSION   NM_001106462 XM_001070674 XM_215674
VERSION     NM_001106462.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 879)
  AUTHORS   Bar-Peled L and Sabatini DM.
  TITLE     Regulation of mTORC1 by amino acids
  JOURNAL   Trends Cell Biol 24 (7), 400-406 (2014)
   PUBMED   24698685
  REMARK    Review article
REFERENCE   2  (bases 1 to 879)
  AUTHORS   Bar-Peled L, Schweitzer LD, Zoncu R and Sabatini DM.
  TITLE     Ragulator is a GEF for the rag GTPases that signal amino acid
            levels to mTORC1
  JOURNAL   Cell 150 (6), 1196-1208 (2012)
   PUBMED   22980980
REFERENCE   3  (bases 1 to 879)
  AUTHORS   Hu N, Zhang J, Cui W, Kong G, Zhang S, Yue L, Bai X, Zhang Z, Zhang
            W, Zhang X and Ye L.
  TITLE     miR-520b regulates migration of breast cancer cells by targeting
            hepatitis B X-interacting protein and interleukin-8
  JOURNAL   J Biol Chem 286 (15), 13714-13722 (2011)
   PUBMED   21343296
REFERENCE   4  (bases 1 to 879)
  AUTHORS   Marusawa H, Matsuzawa S, Welsh K, Zou H, Armstrong R, Tamm I and
            Reed JC.
  TITLE     HBXIP functions as a cofactor of survivin in apoptosis suppression
  JOURNAL   EMBO J 22 (11), 2729-2740 (2003)
   PUBMED   12773388
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473952.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215674.4, XM_001070674.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM074803.1, CB315651.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..879
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..879
                     /gene="Lamtor5"
                     /gene_synonym="Hbxip"
                     /note="late endosomal/lysosomal adaptor, MAPK and MTOR
                     activator 5"
                     /db_xref="GeneID:295357"
                     /db_xref="RGD:1305005"
     exon            1..254
                     /gene="Lamtor5"
                     /gene_synonym="Hbxip"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..495
                     /gene="Lamtor5"
                     /gene_synonym="Hbxip"
                     /note="hepatitis B virus x interacting protein"
                     /codon_start=1
                     /product="ragulator complex protein LAMTOR5"
                     /protein_id="NP_001099932.1"
                     /db_xref="GeneID:295357"
                     /db_xref="RGD:1305005"
                     /translation="MPANAGSVVVAMSFRKECERGATMNLFPLETPSARPPRSSHVTE
                     ACCEGGSVLPRGLGLGRTVYGMEATLEQHLEDTMKNPSIVGVLCTDSQGLNLGCRGTL
                     SDEHAGVISVLAQQAAKLTSDPTDIPVVCLESDNGNVMIQKHDGITVAVHKMAS"
     exon            255..316
                     /gene="Lamtor5"
                     /gene_synonym="Hbxip"
                     /inference="alignment:Splign:2.1.0"
     exon            317..434
                     /gene="Lamtor5"
                     /gene_synonym="Hbxip"
                     /inference="alignment:Splign:2.1.0"
     exon            435..879
                     /gene="Lamtor5"
                     /gene_synonym="Hbxip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgaaggccca ttacaccgaa tcaaatgcca gctaatgccg gttctgtagt ggtagctatg
       61 tcttttcgta aagagtgcga acgcggcgcc acgatgaatt tgttccctct ggagacgccg
      121 tccgcgcgcc cgcctcggtc aagtcacgtg accgaggctt gctgtgaagg aggaagtgtt
      181 ttgccgaggg gtcttgggct ggggcggaca gtgtacggga tggaggcgac tttggagcag
      241 catttggagg acacaatgaa gaatccatcc attgttggag tcctatgcac agattcacaa
      301 ggacttaatc tgggctgccg tggtaccctg tcggatgagc atgctggagt gatatctgtt
      361 ctcgcccagc aggcagctaa gctgacctct gaccccaccg acatccctgt agtgtgttta
      421 gagtcagata acgggaatgt tatgatccag aaacacgatg gcatcacagt ggctgtgcac
      481 aaaatggcct cttgacatct gatgccagct ctccagtggt ctcccaccgg gattcagtca
      541 tgcctgtctc agttaacttg taaaactatt aaagttccag aaatcgggcc attcacttaa
      601 tgtccaatgt ggacttctta ttaatatgac agtcagttac caagacgtca gttaggagtg
      661 tggtggcctt gtctgggctt ttgtcactct gctctttggt gacagccact gtagtccagg
      721 atcatatccc tcatggccta gaactgtgta gcccaggctg acttcaaatt tatggtcttc
      781 ctgcttcaaa ctcctatatc ctgggattta gcatttgtca tggtctaggt cactttgtat
      841 atagaacttt gttgtggtca ataaacctat tctgaggga
//
