LOCUS       NM_001012015            1927 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus lysosomal-associated membrane protein 3 (Lamp3),
            mRNA.
ACCESSION   NM_001012015 XM_221288
VERSION     NM_001012015.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1927)
  AUTHORS   Dominguez-Bautista,J.A., Klinkenberg,M., Brehm,N., Subramaniam,M.,
            Kern,B., Roeper,J., Auburger,G. and Jendrach,M.
  TITLE     Loss of lysosome-associated membrane protein 3 (LAMP3) enhances
            cellular vulnerability against proteasomal inhibition
  JOURNAL   Eur J Cell Biol 94 (3-4), 148-161 (2015)
   PUBMED   25681212
REFERENCE   2  (bases 1 to 1927)
  AUTHORS   White,C., Yuan,X., Schmidt,P.J., Bresciani,E., Samuel,T.K.,
            Campagna,D., Hall,C., Bishop,K., Calicchio,M.L., Lapierre,A.,
            Ward,D.M., Liu,P., Fleming,M.D. and Hamza,I.
  TITLE     HRG1 is essential for heme transport from the phagolysosome of
            macrophages during erythrophagocytosis
  JOURNAL   Cell Metab 17 (2), 261-270 (2013)
   PUBMED   23395172
REFERENCE   3  (bases 1 to 1927)
  AUTHORS   Mine,K.L., Shulzhenko,N., Yambartsev,A., Rochman,M., Sanson,G.F.,
            Lando,M., Varma,S., Skinner,J., Volfovsky,N., Deng,T., Brenna,S.M.,
            Carvalho,C.R., Ribalta,J.C., Bustin,M., Matzinger,P., Silva,I.D.,
            Lyng,H., Gerbase-DeLima,M. and Morgun,A.
  TITLE     Gene network reconstruction reveals cell cycle and antiviral genes
            as major drivers of cervical cancer
  JOURNAL   Nat Commun 4, 1806 (2013)
   PUBMED   23651994
REFERENCE   4  (bases 1 to 1927)
  AUTHORS   Zhou,Z., Xue,Q., Wan,Y., Yang,Y., Wang,J. and Hung,T.
  TITLE     Lysosome-associated membrane glycoprotein 3 is involved in
            influenza A virus replication in human lung epithelial (A549) cells
  JOURNAL   Virol J 8, 384 (2011)
   PUBMED   21810281
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1927)
  AUTHORS   Albrecht,S., Usmani,S.M., Dietl,P. and Wittekindt,O.H.
  TITLE     Plasma membrane trafficking in alveolar type II cells
  JOURNAL   Cell Physiol Biochem 25 (1), 81-90 (2010)
   PUBMED   20054147
REFERENCE   6  (bases 1 to 1927)
  AUTHORS   Salaun,B., de Saint-Vis,B., Pacheco,N., Pacheco,Y., Riesler,A.,
            Isaac,S., Leroux,C., Clair-Moninot,V., Pin,J.J., Griffith,J.,
            Treilleux,I., Goddard,S., Davoust,J., Kleijmeer,M. and Lebecque,S.
  TITLE     CD208/dendritic cell-lysosomal associated membrane protein is a
            marker of normal and transformed type II pneumocytes
  JOURNAL   Am J Pathol 164 (3), 861-871 (2004)
   PUBMED   14982840
REFERENCE   7  (bases 1 to 1927)
  AUTHORS   Salaun,B., de Saint-Vis,B., Clair-Moninot,V., Pin,J.J.,
            Barthelemy-Dubois,C., Kissenpfennig,A., Peronne,C., Bates,E.,
            Mattei,M.G. and Lebecque,S.
  TITLE     Cloning and characterization of the mouse homologue of the human
            dendritic cell maturation marker CD208/DC-LAMP
  JOURNAL   Eur J Immunol 33 (9), 2619-2629 (2003)
   PUBMED   12938238
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083787.1.
            
            On Feb 11, 2005 this sequence version replaced XM_221288.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083787.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1927
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1927
                     /gene="Lamp3"
                     /note="lysosomal-associated membrane protein 3"
                     /db_xref="GeneID:303801"
                     /db_xref="RGD:1307928"
     exon            1..142
                     /gene="Lamp3"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1323
                     /gene="Lamp3"
                     /note="lysosome-associated membrane glycoprotein 3;
                     LAMP-3"
                     /codon_start=1
                     /product="lysosome-associated membrane glycoprotein 3
                     precursor"
                     /protein_id="NP_001012015.1"
                     /db_xref="GeneID:303801"
                     /db_xref="RGD:1307928"
                     /translation="MPGQTSAVAVLLCLAVILHGYQIREKEFPEARGYLQYTATTTEQ
                     ITAKPPLPLTNQTSHATLASRSKDDYIQTAAETSTFEDTAHITMKTAIPVTTKSLLPI
                     SSTSYTFVRTNNSHMTASSTEDTIGSGSITHLPFPTTRASLAAVNHITGRSTQLGGQT
                     TLPKALFTPSHESTTTQRPTLSTIVSELTPTGKDRSTTSSVPLVPRPTFVTWSSPAKI
                     GTYEVLNGSRLCIKAEMGIALIVQEKGLDSATQRHFNIDPSLTHASGKCGSQNSNLFL
                     NFQGGSVNVTFTKEENLYYVSEVGAYLTISNTEKTYQGKSTMMMFETVVGHSFKCVSE
                     QSIQLSAQLQMKTMNIHLQAFDFEGDSFGIVDECLSDYTVVLPVVGIIVVVLCVVGLG
                     IYKIRQRRQSSAYQRI"
     exon            143..834
                     /gene="Lamp3"
                     /inference="alignment:Splign:2.1.0"
     exon            835..963
                     /gene="Lamp3"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1021
                     /gene="Lamp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1189
                     /gene="Lamp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1899
                     /gene="Lamp3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttccttggt gttctgtgga tctgctctga aattgattcc attcttacag ttcagaagac
       61 ccaagcacac aacagcagta actaacctca cctgtcatgc ctgggcagac ctctgcagta
      121 gctgtactcc tgtgtctggc tgtaatttta catggctatc aaataagaga aaaagaattt
      181 ccagaagcca gaggctatct tcaatatact gcaacaacaa cagaacagat cacagcaaaa
      241 cctccactac cactgactaa ccaaacatct catgcaactt tagcatcaag gtccaaggat
      301 gattacattc aaacggctgc cgaaacttcc acttttgaag acacagccca cataacaatg
      361 aaaacagcaa tcccagtaac tacgaagagc cttctaccca tcagctcaac tagctatacc
      421 tttgttagaa ctaataactc acacatgact gcttcatcta ctgaagatac tattggctct
      481 ggctcaatta cacatttacc atttcctaca accagagcta gtctagctgc tgtcaatcat
      541 ataactggga gaagtaccca acttggtggt cagactaccc ttcccaaagc acttttcaca
      601 ccatcacacg aaagcacaac cactcagagg ccaactctat ccactattgt ctcagaacta
      661 acacctacag gcaaggacag atcaacaact tcatctgttc ccttagttcc caggcctact
      721 tttgtaactt ggtcatcacc tgccaagatt ggaacttatg aagtactaaa tggaagcagg
      781 ctctgtataa aagcagagat gggaatagcg ctgattgttc aagaaaaggg tttggattct
      841 gcaacccaga ggcacttcaa cattgacccc agtctaaccc atgcatctgg gaaatgtggc
      901 tcccaaaact ccaacctctt cttgaatttc cagggtggat ccgtgaatgt cacatttacc
      961 aaggaagaaa acttatatta cgttagtgaa gttggagctt atttgaccat ctcaaataca
     1021 gagaagacct accaaggaaa gagtactatg atgatgtttg agacagtagt tgggcattct
     1081 ttcaagtgtg tcagtgagca gagcatccag ctatcagctc agcttcaaat gaaaacaatg
     1141 aatatccatc ttcaggcctt tgattttgaa ggagactcct ttggaattgt ggacgagtgt
     1201 ttgtcagact acacagttgt gcttcctgtg gttgggatca tcgtggttgt cctctgtgtt
     1261 gtgggtctgg gcatctacaa aatccgccaa aggcgtcagt catctgcata ccagagaatc
     1321 taatttgaaa ccaaaggaaa tggcaataaa ggagtttaaa aagaatttca tcatttccag
     1381 aacgttggag gaatctcttc ctcactacct tcttccaaaa ccaatgagtg attagtgatt
     1441 taaattgaag cagcatatcg gttctgaata tttttgctca tttcatgaaa gactaaggaa
     1501 gatactgagc agtattttct agcttttgtt ggaaaaattt aactattcaa atgaatattt
     1561 gagatacaca gaattaatat aatgttcaaa ggtcatagat atttacaaat tataaaccaa
     1621 aataattgat tttaattagt cctaccttta tttgcctaga gaaatttatt ttaacatcaa
     1681 catttttatt ttaagatatt ttgctggatt ttcttaccat ttgtgcttat tgaggtatga
     1741 atatttgaca tggtactcac cttctattta aatatttcta gttatcaaaa taacataact
     1801 cgtattgttt agactttaca tgaaaataag atactcttta ctcatgacac atttcagaac
     1861 taataaagac taagaaatcg cttcctacag acaacaaaaa aaaaaaaaaa aaaaaaaaaa
     1921 aaaaaaa
//
