LOCUS       NM_001107830            6512 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus laminin subunit gamma 3 (Lamc3), mRNA.
ACCESSION   NM_001107830 XM_001079850 XM_231139
VERSION     NM_001107830.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6512)
  AUTHORS   Pinzon-Duarte G, Daly G, Li YN, Koch M and Brunken WJ.
  TITLE     Defective formation of the inner limiting membrane in laminin
            beta2- and gamma3-null mice produces retinal dysplasia
  JOURNAL   Invest Ophthalmol Vis Sci 51 (3), 1773-1782 (2010)
   PUBMED   19907020
REFERENCE   2  (bases 1 to 6512)
  AUTHORS   Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C,
            Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D,
            Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N,
            Kimata K, Hayashizaki Y and Sekiguchi K.
  TITLE     Transcriptome-based systematic identification of extracellular
            matrix proteins
  JOURNAL   Proc Natl Acad Sci U S A 105 (35), 12849-12854 (2008)
   PUBMED   18757743
REFERENCE   3  (bases 1 to 6512)
  AUTHORS   Yan HHN and Cheng CY.
  TITLE     Laminin alpha 3 forms a complex with beta3 and gamma3 chains that
            serves as the ligand for alpha 6beta1-integrin at the apical
            ectoplasmic specialization in adult rat testes
  JOURNAL   J Biol Chem 281 (25), 17286-17303 (2006)
   PUBMED   16608848
  REMARK    GeneRIF: a complex of laminin alpha 3, beta3 and gamma3 chains
            serves as the ligand for alpha 6beta1-integrin at the apical
            ectoplasmic specialization in adult rat testes
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079850.1, XM_231139.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6512
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..6512
                     /gene="Lamc3"
                     /note="laminin subunit gamma 3"
                     /db_xref="GeneID:311862"
                     /db_xref="RGD:1309399"
     exon            1..454
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..4797
                     /gene="Lamc3"
                     /note="laminin gamma 3; laminin subunit gamma-3-like"
                     /codon_start=1
                     /product="laminin subunit gamma-3 precursor"
                     /protein_id="NP_001101300.1"
                     /db_xref="GeneID:311862"
                     /db_xref="RGD:1309399"
                     /translation="MAVSGILSRLATVVCVALVMLKAHCATGAGMGSCYDGAGRAQRC
                     LPEFENAAFGRRAEASHTCGQPPEDFCPHVGAPGAGPQCQRCDDADPRRRHDASYLTD
                     FHSPDDSTWWQSPSMAFGVQYPTSVNLTLHLGKAYEITYVRLKFHTSRPESFAIYKRT
                     HTGGPWEPYQYYSASCQKTYGHPEGHYLRPGEDERVAFCTSEFSDISPLNGGNVAFST
                     LEGRPSAYNFEESPVLQEWVTSTDLLISLDRLNTFGDDIFKDPRVLQSYYYAVSDFSV
                     GGRCKCNGHASACGPNEAGQLACHCQHNTTGVDCERCLPFFQDRPWARGTAEDANECL
                     PCNCSGHSEECTFDRELYRSTGHGGHCQRCRDHTAGPHCEHCEKNYYRWDPKTPCQPC
                     DCHPAGSLSLQCDNSGTCPCKLTVTGWKCDRCLPGFHSLSEGGCRPCTCNVAGSLGTC
                     DPRSGNCPCKENVEGGLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCAPASGFQEHH
                     IRSDFRHGADGWQARSTEVSERPLQWSQSGILLGLRGGEELSAPEKFLGDQRLSYGQP
                     LILTLQVPPGGSPPPMQLRLEGAGLSLALKPSNLPSSQDTRQPGRVQLQFLLQETSEE
                     AEPPLPAFHFQRLLSNLTTLSIWTSGQGLGHSGHVLLCEVHLTSARPQRGLAPPASWV
                     ETCLCPQGYTGQFCEFCALGYKREIPHGGPYTNCIPCTCNQHGTCDPNTGICLCGHHT
                     EGPSCERCMPGFYGNAFSGHADDCQPCPCPGQSACTTIPESRDVVCTHCPPGQRGRRC
                     ESCEDGFFGDPLGLSGAPQPCRRCQCSRNVDLNAVGNCDPHSGRCLRCLHNTTGAHCE
                     HCQEGFYGSALATRPADKCAPCSCDPRGSSSQKTCNPATGQCACLPYVTGRDCSRCSP
                     GFYDLQPGRGCQSCKCHPVGSLENKCHPKTGQCPCRPGVTGQACDRCQLGFFGFSIKG
                     CRDCRCSPLGAASPQCHENSTCVCRPGFVGYKCDRCQDNFFLVDGDTGCQECPTCYAL
                     VKEEAAKLKTRLMLMEGWLQGSECGSPWGPLDILQGEAPRGDVYQGHHLFQEARGTFL
                     EQMVGLEESVKATWEQLQVLRGNAHCAQAGAQKTCNQLAELGETLRSSEEEVLRAASA
                     LSFLANLQEGSSAPTNWGRLASEAYILTRSHRDTATKIEATVERALLASNTSYELLWK
                     LLKGSVASEAQQELEERYQEVQAAQTALGIAVAEALPKAEKALATVKQVVGAAAPRLG
                     SMVTPEAMDSQARYLGRRVKALEQKLQQNQAGQAVGALQVEAGRALRKVEPFLQLRNK
                     TTAALTQVSSAVQAAKVTVIGAKTLLADLEGMKLRFPLPKEQAALKRKAGSIRTRLLK
                     DTKRKTKQAERMLGNAASLSSNSQKRSKEAELMSKENAKLARAFLREGKQNYRHASRL
                     ASQTQATLRQASRLVLTSEARKQELEEAKQVASGLSTVERQIRESRISLEKDTKVLSE
                     LLAKLGSLGTHQAPAQTLNETQQALESLRLQLDSHGSLHHKLRQLEEESARQELQIQS
                     FENDLAEIRADKHNLETILSSLPENCAS"
     exon            455..759
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            760..890
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1057
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1246
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1364
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1463
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..1600
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..1711
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1904
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1905..2023
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2024..2248
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2249..2437
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2438..2683
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2684..2834
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2835..2977
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2978..3156
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3157..3298
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3299..3504
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3505..3581
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3582..3716
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3717..3864
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            3865..4002
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            4003..4105
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            4106..4305
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            4306..4452
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            4453..4552
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
     exon            4553..6512
                     /gene="Lamc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcagatcaa ggcgcagagt agataccggc gcggtgagga gcgaggcgcc ggccatggct
       61 gtgtccggga tcctgtcccg cctggcaacg gtggtatgtg tggcgttggt gatgctgaag
      121 gcgcactgcg cgacgggtgc gggcatgggc tcttgctacg acggtgcggg acgcgcacag
      181 cgctgtctgc ctgagttcga gaacgcggcg ttcggccgac gcgccgaggc ctcgcacacg
      241 tgcggacagc ccccagagga cttctgtccg cacgtggggg caccaggagc tgggccacag
      301 tgccagcgct gtgatgatgc tgacccccgg cgacgccacg acgcctccta cctcacagac
      361 ttccacagcc ctgatgacag cacctggtgg caaagtccgt ccatggcctt cggggtgcag
      421 tatcccactt cggttaacct gaccctgcat ctagggaagg cctatgagat cacctatgtg
      481 aggctaaagt tccacaccag ccgccccgag agctttgcca tctacaagcg cacgcacacg
      541 ggtggcccct gggagcccta ccaatactac agtgcctcct gccagaaaac ctatggccat
      601 cctgagggcc actacctgcg acctggtgaa gatgagaggg tggctttctg cacctctgag
      661 ttcagcgaca tctcccccct gaatgggggc aacgtggcct tctccactct ggagggccgt
      721 cccagtgcct acaactttga ggagagccct gtgctgcagg agtgggttac cagcaccgat
      781 ctcctgatct ctctggatcg tctcaacacg tttggggatg acatcttcaa ggaccccaga
      841 gtgctccagt cttactacta cgctgtgtct gacttctctg tgggtggcag gtgcaaatgc
      901 aatggtcacg ccagtgcgtg cgggcccaac gaggctggtc agctggcttg tcactgccag
      961 cacaacacca cgggagtgga ctgtgagcgt tgtctaccct tcttccagga ccgtccgtgg
     1021 gcccgcggca ccgcagagga tgccaacgag tgtctgccct gcaactgtag tgggcactct
     1081 gaggagtgca cgtttgacag ggagctctat cggagcacgg gccatggtgg gcactgccag
     1141 cgctgccgag accacacagc tgggccacat tgtgagcatt gtgagaagaa ctattacaga
     1201 tgggacccga agacaccatg ccaaccctgt gactgccacc cagcaggctc cctgagtctc
     1261 cagtgtgaca actcgggcac ctgtccctgc aagctgacgg tgactggctg gaagtgtgat
     1321 cgctgcctgc ctggattcca ctcactcagt gagggcggct gcagaccctg tacctgcaat
     1381 gtcgctggca gcttgggcac ctgcgatccc cgaagtggaa actgcccctg caaagagaat
     1441 gtggaaggcg gtctgtgtga cagatgccgc cctgggactt ttaacctgca gccccataac
     1501 ccagccggct gcagtagctg cttctgttac ggccactcca aggtgtgtgc ccctgcttca
     1561 gggttccagg aacaccacat ccgctcagac ttccgccatg gagctgatgg ctggcaggcc
     1621 agaagcacag aggtgtcaga gcgtcctctg caatggagcc agagcgggat cctcctgggc
     1681 ctgcgaggag gggaggaact ctcagcccca gagaagttcc tgggagacca gagactcagc
     1741 tatggacagc cactcatact gaccctccaa gtaccccccg ggggctcccc acctcctatg
     1801 cagctgagac tggagggggc aggtttatct ctggctctga aaccctccaa tctacccagc
     1861 tctcaggaca ccaggcagcc aggacgagtt cagctccagt tcctcctgca ggagacttct
     1921 gaagaggcag agcctccact gcccgccttc cacttccagc gcctgctttc caatctgacc
     1981 actctgagca tctggaccag tggccaaggc ctgggccact ctggccacgt gctcttgtgt
     2041 gaagtccatc tcacatcggc ccggcctcag cgtgggcttg ccccaccagc ctcttgggtg
     2101 gagacctgct tatgtcccca gggatacacg ggccagttct gtgaattctg tgctctggga
     2161 tacaaaagag aaatacctca tgggggtccc tataccaact gcatcccctg cacctgcaac
     2221 cagcatggaa cctgtgaccc caacacaggg atctgcctgt gtggccacca cacggagggt
     2281 ccatcctgtg agcgatgcat gccaggtttc tacggtaacg ccttctcagg ccacgctgat
     2341 gattgccagc cctgtccatg ccctggccaa tcagcctgca cgaccatccc agagagtaga
     2401 gatgtggtgt gcacacactg cccccctggt cagagaggac gacgctgtga gagctgtgaa
     2461 gatggcttct tcggagatcc cctaggactc tctggagctc cccagccctg ccgccgatgc
     2521 cagtgcagca ggaacgtgga tctcaatgct gtgggcaact gcgatcctca ttctggccgc
     2581 tgtctgcgct gtctgcacaa cacaacaggg gcccactgcg agcactgtca ggagggtttc
     2641 tatgggagtg ccttggccac gaggcctgcg gacaaatgtg ctccctgcag ctgtgacccg
     2701 aggggctcaa gcagtcagaa gacctgcaac ccagcgactg gccagtgtgc ctgcctgcct
     2761 tacgtcaccg ggagggattg cagccgctgc agccctggct tctacgacct ccagcctggg
     2821 aggggctgcc agagctgcaa atgtcaccca gtgggctcct tggagaacaa gtgccacccc
     2881 aagactggcc agtgcccctg tcgacccggt gtcaccggcc aagcctgtga cagatgccag
     2941 ctgggtttct ttggcttctc catcaagggc tgccgagact gtaggtgttc cccactgggt
     3001 gctgcctcac cccagtgcca tgagaacagc acgtgtgtgt gccggcctgg cttcgtgggc
     3061 tataaatgtg accgctgcca ggacaatttc ttcctcgtgg atggtgacac aggctgccaa
     3121 gagtgcccca cctgctatgc tctagtgaag gaggaggcag ccaagctgaa gaccaggctg
     3181 atgctgatgg aggggtggct tcaggggtcc gagtgtggca gcccctgggg accactagac
     3241 attctgcagg gagaagcccc tcggggggat gtctaccaag gtcaccacct atttcaagag
     3301 gcccggggga ccttcctgga gcagatggtg ggcctggagg agtctgtgaa ggccacttgg
     3361 gagcagctgc aggtgctgag agggaacgca cactgtgccc aggctggagc tcagaagacc
     3421 tgcaaccagc tggcagagct gggggagacg ctgcgttcct cagaggagga ggtcctgcgt
     3481 gcagcctcag ctctctcatt tctggcaaat cttcaggaag gatccagcgc acccaccaat
     3541 tggggtcgcc tggcatcaga ggcctacatc ctcaccagga gccacaggga cacagccacc
     3601 aagatcgaag ctaccgtgga aagggccctg ctcgcctcca acaccagcta tgagctcctg
     3661 tggaagctgt tgaaaggcag tgtggcctca gaggcccagc aggaactgga ggagaggtac
     3721 caggaggtgc aggcagctca gactgccctg ggcatagctg tggcagaggc gctgcccaaa
     3781 gctgaaaagg cactagccac ggtgaagcaa gtcgttggtg ccgcagcccc acgtctgggc
     3841 tcgatggtca cccctgaagc aatggactcc caagctagat acctaggccg gagagtgaaa
     3901 gccctggagc agaagctgca gcagaaccag gcaggccaag cggtgggagc cctgcaggta
     3961 gaggctggga gagccttgag gaaggtggag ccctttctgc agctacgaaa caagaccaca
     4021 gctgccctga cacaggtttc ctcagctgtc caagctgcta aggtgaccgt cataggagcg
     4081 aagaccctgc tagctgacct agagggaatg aagctaaggt tccctctacc caaggagcag
     4141 gcagcgctga agaggaaagc aggcagcatc aggaccaggc tcttgaagga cacgaagaga
     4201 aagaccaagc aggcagagag gatgctggga aatgctgcct cgctctcctc caactcccag
     4261 aagagaagca aagaagcaga actgatgtcc aaggagaatg ccaagcttgc cagagctttc
     4321 ctgagggaag ggaagcagaa ctaccgtcat gccagccgac tcgccagcca gacccaggcc
     4381 acactccgcc aggcctctcg cctggtgctg acctcagaag cacggaaaca ggagctggaa
     4441 gaagctaaac aggtggcctc tgggctgagc actgtggagc gccagatccg agagtctcgg
     4501 atctccttgg agaaggacac caaggtcctg tcagagctgc tcgcgaaact ggggtccctg
     4561 ggtacccacc aagcccctgc tcagaccctg aacgagaccc agcaggcact agaaagcttg
     4621 aggctgcagc tggattcaca tggatccttg catcacaaac taaggcagct ggaggaagag
     4681 tctgctcgac aggagctgca gatccagagc tttgagaacg acctcgctga gatccgcgct
     4741 gacaagcaca acttggagac cattctaagc agtctaccag agaactgtgc cagctagacc
     4801 ctggcacacc ctccccaccc tgctgcttcc tgtcctctcc ccgtaggtgt cccaggtctg
     4861 cctgttgtat gttcatgtga atgcttcttt gccggtgtgt cttcggtctg cagcaggagt
     4921 agtacatgtt tgttcctcca cagatggccc tgtgtgtagc cctcagtgtg tgctccctga
     4981 acaggcatca gcatacacac cccagggtca gtaaggggca tgtctgcatt tgcacatatg
     5041 tgcgcgcgat gcacttgtgt gttcaagacc acatgtggat gcacacacat gaaagactag
     5101 agctgtcaag aggcagtcct gagcttgggt atactctgca tcctgggtgg gtcctgttag
     5161 gacatatttc cctgcagggc tgacatatct acaaccctcc ctccagaaat caggggccga
     5221 acgggggtgg tacctccgag gctgagaaac tatcctcaga gatcttgaga agcctcagaa
     5281 agtcccacat gcatggtcac agaactggcc ctggacccac tatactcctc tgtccctaac
     5341 tggtcaccca gaagctctgt gaactgaggt accagacaga tcaagagatg cccagatcct
     5401 aacagggttt ccagaagtgg catctgcggc atgtgggcct gcaaagccac agggcaaggt
     5461 acagatgtta gtgtcttttg tggatgattc cctctggaga catgcactac agctgtttca
     5521 tcgaggaagc acctgaccca accaccttca ctccctacct gaagtaccag gttcctcagg
     5581 gtctgggtca tgacaccggg aacagccctt tgggccttgc caagccggtt agccttatga
     5641 ttgacacttc tcagactggt cctgtgaccc cgcctgccct gaggtatgcc acaggggtgt
     5701 gagagcctgg ctgtcattct agacctgctg cccgtggact gccttctcct agaaatccct
     5761 ggcatttcct cctgatgccc cctctttttc tcagaactct cttagcacac agccgggcct
     5821 aggcgctggg ataacagtca cctttgcaag gccaatccct tccccaggtc ccagaggaac
     5881 agatagttac gtggactgat tctgattatg aggaaataaa ggaccctttc ctgagctgtg
     5941 tgctgtgcct tcgatcctgc agtgctggtg tggcagccag ggcctgctgc gggtatacac
     6001 agagcacttc tgtggctggc cccgaaagca ggtagaacct acgtttgtga tcccacatgt
     6061 gggaaggtgg cagaactggc cttgtgccat gctggggtct gttatgttgg gctttgcagg
     6121 ggcactgtga ccaccacctt tcctctcaga tccagggggc tttcagacaa aggtgagggg
     6181 cccggataga ggtggtatgc agagagcttc tctgctgatc cctggttcag ggtggagaca
     6241 ctgagacaga gaacggaact taattctgtc ctgtaagggg aaaggaggga cacctttgag
     6301 gggaggagga catgggcctg ggcctggaag tgtggagaga cagagaggag aacagcccat
     6361 acaagatggt aggcggcagc caaggttaca gggcaccagc ctggccagca caggtcattg
     6421 caaacttaga ttagggcagg ttgtaaagca tgctctattt tgtcaaggct ttttggtcac
     6481 aaggccaaaa tgagagccag attagcttca ac
//
