LOCUS       NM_053966               7636 bp    mRNA    linear   ROD 20-MAY-2024
DEFINITION  Rattus norvegicus laminin subunit gamma 1 (Lamc1), mRNA.
ACCESSION   NM_053966 XM_001071300 XM_341133
VERSION     NM_053966.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7636)
  AUTHORS   Wu,Q., Yuan,K., Yao,Y., Yao,J., Shao,J., Meng,Y., Wu,P. and Shi,H.
  TITLE     LAMC1 attenuates neuronal apoptosis via FAK/PI3K/AKT signaling
            pathway after subarachnoid hemorrhage
  JOURNAL   Exp Neurol 376, 114776 (2024)
   PUBMED   38609046
  REMARK    GeneRIF: LAMC1 attenuates neuronal apoptosis via FAK/PI3K/AKT
            signaling pathway after subarachnoid hemorrhage.
REFERENCE   2  (bases 1 to 7636)
  AUTHORS   Ram,R., Wakil,S.M., Muiya,N.P., Andres,E., Mazhar,N., Hagos,S.,
            Alshahid,M., Meyer,B.F., Morahan,G. and Dzimiri,N.
  TITLE     A common variant association study in ethnic Saudi Arabs reveals
            novel susceptibility loci for hypertriglyceridemia
  JOURNAL   Clin Genet 91 (3), 371-378 (2017)
   PUBMED   27599772
REFERENCE   3  (bases 1 to 7636)
  AUTHORS   Barallobre-Barreiro,J., Gupta,S.K., Zoccarato,A.,
            Kitazume-Taneike,R., Fava,M., Yin,X., Werner,T., Hirt,M.N.,
            Zampetaki,A., Viviano,A., Chong,M., Bern,M., Kourliouros,A.,
            Domenech,N., Willeit,P., Shah,A.M., Jahangiri,M., Schaefer,L.,
            Fischer,J.W., Iozzo,R.V., Viner,R., Thum,T., Heineke,J.,
            Kichler,A., Otsu,K. and Mayr,M.
  TITLE     Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin
            Activity in Human Atrial Fibrillation
  JOURNAL   Circulation 134 (11), 817-832 (2016)
   PUBMED   27559042
REFERENCE   4  (bases 1 to 7636)
  AUTHORS   Barallobre-Barreiro,J., Oklu,R., Lynch,M., Fava,M., Baig,F.,
            Yin,X., Barwari,T., Potier,D.N., Albadawi,H., Jahangiri,M.,
            Porter,K.E., Watkins,M.T., Misra,S., Stoughton,J. and Mayr,M.
  TITLE     Extracellular matrix remodelling in response to venous
            hypertension: proteomics of human varicose veins
  JOURNAL   Cardiovasc Res 110 (3), 419-430 (2016)
   PUBMED   27068509
REFERENCE   5  (bases 1 to 7636)
  AUTHORS   Pokrywczynska,M., Lewandowska,M.A., Krzyzanowska,S., Jundzill,A.,
            Rasmus,M., Warda,K., Gagat,M., Deptula,A., Helmin-Basa,A.,
            Holysz,M., Nowacki,M., Buchholz,L., Bodnar,M., Marszalek,A.,
            Grzanka,A., Jozwicki,W., Michalkiewicz,J. and Drewa,T.
  TITLE     Transdifferentiation of Bone Marrow Mesenchymal Stem Cells into the
            Islet-Like Cells: the Role of Extracellular Matrix Proteins
  JOURNAL   Arch Immunol Ther Exp (Warsz) 63 (5), 377-384 (2015)
   PUBMED   25957583
  REMARK    GeneRIF: enhances expression of insulin, and promotes
            transdifferentiation of bone marrow mesenchymal stem cells into
            islet-like cells
REFERENCE   6  (bases 1 to 7636)
  AUTHORS   Qin,P., Piechocki,M., Lu,S. and Kurpakus,M.A.
  TITLE     Localization of basement membrane-associated protein isoforms
            during development of the ocular surface of mouse eye
  JOURNAL   Dev Dyn 209 (4), 367-376 (1997)
   PUBMED   9264260
REFERENCE   7  (bases 1 to 7636)
  AUTHORS   Vanden Heuvel,G.B., Leardkamolkarn,V., St John,P.L. and
            Abrahamson,D.R.
  TITLE     Carboxy terminal sequence and synthesis of rat kidney laminin gamma
            1 chain
  JOURNAL   Kidney Int 49 (3), 752-760 (1996)
   PUBMED   8648916
REFERENCE   8  (bases 1 to 7636)
  AUTHORS   Noakes,P.G., Miner,J.H., Gautam,M., Cunningham,J.M., Sanes,J.R. and
            Merlie,J.P.
  TITLE     The renal glomerulus of mice lacking s-laminin/laminin beta 2:
            nephrosis despite molecular compensation by laminin beta 1
  JOURNAL   Nat Genet 10 (4), 400-406 (1995)
   PUBMED   7670489
REFERENCE   9  (bases 1 to 7636)
  AUTHORS   Volpe,C.M., Koo,J., Miloro,S.M., Driscoll,D.L., Nava,H.R. and
            Douglass,H.O. Jr.
  TITLE     The effect of extended lymphadenectomy on survival in patients with
            gastric adenocarcinoma
  JOURNAL   J Am Coll Surg 181 (1), 56-64 (1995)
   PUBMED   7599772
REFERENCE   10 (bases 1 to 7636)
  AUTHORS   Schuger,L., Varani,J., Killen,P.D., Skubitz,A.P. and Gilbride,K.
  TITLE     Laminin expression in the mouse lung increases with development and
            stimulates spontaneous organotypic rearrangement of mixed lung
            cells
  JOURNAL   Dev Dyn 195 (1), 43-54 (1992)
   PUBMED   1292752
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Feb 10, 2021 this sequence version replaced NM_053966.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The extent of this transcript is supported
            by transcript alignments and orthologous data.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.31857.1,
                                           SRR26643290.42415.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-659               JAXUCZ010000013.1  68051328-68051986   c
            660-964             JAXUCZ010000013.1  67971249-67971553   c
            965-1095            JAXUCZ010000013.1  67967018-67967148   c
            1096-1262           JAXUCZ010000013.1  67964060-67964226   c
            1263-1451           JAXUCZ010000013.1  67960563-67960751   c
            1452-1569           JAXUCZ010000013.1  67959623-67959740   c
            1570-1668           JAXUCZ010000013.1  67959146-67959244   c
            1669-1805           JAXUCZ010000013.1  67958921-67959057   c
            1806-1928           JAXUCZ010000013.1  67958381-67958503   c
            1929-2118           JAXUCZ010000013.1  67958100-67958289   c
            2119-2231           JAXUCZ010000013.1  67956974-67957086   c
            2232-2453           JAXUCZ010000013.1  67954967-67955188   c
            2454-2642           JAXUCZ010000013.1  67954695-67954883   c
            2643-2888           JAXUCZ010000013.1  67951050-67951295   c
            2889-3042           JAXUCZ010000013.1  67950452-67950605   c
            3043-3185           JAXUCZ010000013.1  67949835-67949977   c
            3186-3364           JAXUCZ010000013.1  67948010-67948188   c
            3365-3521           JAXUCZ010000013.1  67947008-67947164   c
            3522-3727           JAXUCZ010000013.1  67942120-67942325   c
            3728-3807           JAXUCZ010000013.1  67941356-67941435   c
            3808-3945           JAXUCZ010000013.1  67938752-67938889   c
            3946-4090           JAXUCZ010000013.1  67937755-67937899   c
            4091-4240           JAXUCZ010000013.1  67936108-67936257   c
            4241-4355           JAXUCZ010000013.1  67935800-67935914   c
            4356-4555           JAXUCZ010000013.1  67934611-67934810   c
            4556-4714           JAXUCZ010000013.1  67933553-67933711   c
            4715-4814           JAXUCZ010000013.1  67929664-67929763   c
            4815-7636           JAXUCZ010000013.1  67924872-67927693   c
FEATURES             Location/Qualifiers
     source          1..7636
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q21"
     gene            1..7636
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /note="laminin subunit gamma 1"
                     /db_xref="GeneID:117036"
                     /db_xref="RGD:621052"
     exon            1..659
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..5071
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /note="laminin, gamma 1"
                     /codon_start=1
                     /product="laminin subunit gamma-1 precursor"
                     /protein_id="NP_446418.1"
                     /db_xref="GeneID:117036"
                     /db_xref="RGD:621052"
                     /translation="MTGGRRAALALQLQRRLWLLLAVLAAVACWVRAAMDECADEGGR
                     PQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQLHLQHGAA
                     FLTDYNNQADTTWWQSQTMLAGVQYPNSINLTLHLGKAFDITYVRLKFHTSRPESFAI
                     YKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNV
                     AFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAIS
                     DFAVGGRCKCNGHASECVKNEFGKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESA
                     NQCLPCDCNGRSQECYFDPELYRSTGHGGHCTNCRDNTDGAKCERCRENFFRLGNTEA
                     CSPCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGS
                     TDECNVETGRCVCKDNVEGFSCERCKPGFFNLESSNPKGCTPCFCFGHSSVCTNAVGY
                     SVYDISSTFQIDEDGWRVEQRDGSEASLEWSSDRQDIAVISDTYFPRYFVAPAKFLGN
                     QVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYIFR
                     LHEATDYPWRPALSPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLQSARPGPGVPA
                     TWVESCTCPVGYGGQFCETCLPGYRRETPSLGPYSPCVLCTCNGHSETCDPETGVCDC
                     RDNTAGPHCEKCSDGYYGDSTLGTSSDCQPCPCPGGSSCAIVPKTKEVVCTHCPTGTA
                     GKRCELCDDGYFGDPLGSNGPVRLCRPCQCNDNIDPNAVGNCNRLTGECLKCIYNTAG
                     FYCDRCKEGFFGNPLAPNPADKCKACACNPYGTVQQQSSCNPVTGQCQCLPHVSGRDC
                     GACDPGFYNLQSGQGCESCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCETNHFG
                     FGPEGCKPCDCHHEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECP
                     ACYRLVKDKVAEHRVKLQELESLIANLGTGDETVTDQAFEDRLKEAEREVTDLLREAQ
                     EVKDVDQNLMDRLQRVNNSLHSQISRLHNIRNTIEETGILAERARSRVESTEQLIEIA
                     SRELEKAKMAAANVSITQPESTGEPNNMTLLAEEARRLAERHKQEADDIVRVAKTANE
                     TSAEAYNLLLRTLAGENQTALEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKA
                     VEIYASVAQLTPVDSEALESEANKIKKEAADLDRLIDQKLKDYEDLREDMRGKEHEVK
                     NLLEKGKAEQQTADQLLARADAAKALAEEAAKKGRNTLQEANDILNNLKDFDRRVNDN
                     KTAAEEALRRIPAINRTIAEANEKTREAQLALGNAAADATEAKNKAHEAERIASGVQK
                     NATSTKADAERTFSEVTDLDNEVNGMLRQLEEAENELKRKQDDADQDMMMAGMASQAA
                     QEAELNARKAKNSVSSLLSQLTDLLEQLGQLDTVDLNKLNEIEGSLNKAKDEMKVSDL
                     DRKVSNLENEARKQEAAILDYDRDIAEIIKDIHNLEDIKKTLPTGCFNTPSIEKP"
     exon            660..964
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1095
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1262
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1451
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1569
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1570..1668
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1805
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1928
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..2118
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..2231
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2453
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            2454..2642
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            2643..2888
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            2889..3042
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3043..3185
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3186..3364
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3365..3521
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3522..3727
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3728..3807
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3808..3945
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            3946..4090
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            4091..4240
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            4241..4355
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            4356..4555
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            4556..4714
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            4715..4814
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
     exon            4815..7636
                     /gene="Lamc1"
                     /gene_synonym="B2e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcgctct cgagtgcgcg ctcggaagtc gggggtcggc gcagagtgca ggctgcgcac
       61 cgggaggcag cggaggcagc gcgatcttcg cttggacgcc cacccatcgg ctctgcgtcc
      121 ggctctcggc ctccagcccg gttcacagcc cggcctcggc ccgcagcgga ggatcggcct
      181 cggggcacgc cgctaggcga gtgcagcgcg gcaccctagc ctttaccgag ggccggcgca
      241 cggcgggatg acgggcggca ggcgggccgc tctggccctg cagctccagc ggcggctgtg
      301 gctgctgctg gctgtgctgg cggccgtggc gtgctgggtc cgggcggcca tggacgagtg
      361 cgcggatgag ggcggccggc cgcagcgctg catgccggag tttgttaatg ccgccttcaa
      421 tgtgaccgtg gtggctacca acacgtgtgg gactccaccc gaggagtact gcgtgcagac
      481 tggagtgacc ggagtcacca agtcctgtca cctgtgcgac gccggccagc tccacctgca
      541 acacggggca gccttcttga ccgactacaa caaccaggcc gacaccacct ggtggcaaag
      601 ccagactatg ctggccgggg tgcagtaccc caactccatc aacctcacgc tgcacctggg
      661 aaaggctttt gacatcactt acgtgcgtct caagttccac accagccgcc cagagagttt
      721 cgccatttat aagcgcactc gggaagacgg gccctggatt ccttaccagt actacagtgg
      781 ctcctgtgag aacacgtact caaaggctaa ccgtggcttc atcaggacgg gaggagatga
      841 gcagcaggcc ttgtgtaccg atgagttcag tgacatttcc cccctcaccg gcggcaacgt
      901 ggccttttca actctggaag gaaggccgag tgcctacaac tttgacaaca gccccgtgct
      961 acaggaatgg gtgacagcca ctgacatcag agtcacactc aatcgcctga acacctttgg
     1021 agatgaagta ttcaatgacc ccaaagtcct caagtcttac tattatgcaa tctcggactt
     1081 tgctgtgggt ggcaggtgta aatgtaatgg acatgccagt gagtgtgtaa agaacgagtt
     1141 tgggaagctc gtgtgcaact gcaagcataa cacatacgga gttgactgtg aaaagtgcct
     1201 gcctttcttc aacgatcggc cgtggaggag agcaactgcc gagagtgcca accagtgcct
     1261 gccttgcgac tgcaatggcc gatcccaaga atgctacttt gaccctgagc tataccgttc
     1321 cactgggcac ggtggccact gtaccaactg ccgggataac acagacggtg ccaagtgcga
     1381 gaggtgccgg gagaacttct tccgcctggg gaacactgaa gcctgctctc cgtgccactg
     1441 cagccccgtt ggttctctca gcacgcagtg tgacagttac ggcaggtgca gctgtaagcc
     1501 cggagtgatg ggtgacaagt gtgaccgttg ccagcctggg ttccattccc tcaccgaggc
     1561 aggatgcagg ccatgctcct gcgacccttc tggcagcacc gacgaatgta atgttgaaac
     1621 aggaagatgc gtttgcaaag acaacgtcga aggcttcagc tgtgagagat gcaaacctgg
     1681 attttttaat ctggaatcct ccaatcctaa gggttgcaca ccctgcttct gctttgggca
     1741 ttcttctgtg tgcaccaatg ctgttggcta cagtgtttat gacatctcct cgacctttca
     1801 gattgatgag gacgggtggc gtgtggagca gagagatggc tcggaggcgt ctcttgagtg
     1861 gtcctcagac cggcaggata ttgctgtgat ctcagacact tacttcccca gatactttgt
     1921 cgcccctgcc aagttcctgg gcaaccaggt cctgagttac gggcagaacc tctcattctc
     1981 cttccgagtg gacagacggg acactcgcct ctccgcagag gatctcgtgc tggaaggagc
     2041 tggcttgaga gtatccgtgc ccttgatcgc tcagggcaac tcgtacccta gcgagaccac
     2101 tgtgaagtac atcttcagac tccatgaagc aacagattac ccttggaggc ctgctctctc
     2161 cccatttgaa tttcagaagc tcctaaacaa cttgacctct atcaagatcc gtggtacata
     2221 cagtgagagg agcgctggat atttggatga tgtcaccttg caaagtgctc gccctgggcc
     2281 cggagtcccc gcaacgtggg tggagtcctg cacctgtcca gtggggtatg gagggcagtt
     2341 ctgtgagaca tgcctcccag gctacagaag agaaacccca agtcttggac cttacagccc
     2401 gtgtgtgctc tgtacctgta atgggcacag tgagacctgt gaccccgaga caggtgtctg
     2461 tgactgcaga gacaatactg ccggcccgca ctgtgagaaa tgtagcgatg ggtactatgg
     2521 agactcaacc ctgggcacct cctctgactg ccagccttgt ccctgccctg gcggctcaag
     2581 ttgtgccatt gtcccaaaga caaaggaagt ggtgtgcaca cactgtccaa ctggcactgc
     2641 cggcaagaga tgtgagctct gtgatgacgg ctactttgga gaccctctgg gcagcaatgg
     2701 acccgtgaga ctctgccgcc catgtcagtg caacgacaac atagacccca acgcagttgg
     2761 caactgcaac cgtctgactg gagaatgcct gaagtgcatc tataacacgg ctggcttcta
     2821 ctgcgaccgg tgcaaagaag ggtttttcgg aaatcccctg gctcccaatc cagcagacaa
     2881 gtgcaaagcc tgcgcctgca atccctatgg tacagtacag cagcagagca gctgtaaccc
     2941 agtgaccggg cagtgccagt gtctgcctca tgtgtcaggc cgggactgtg gcgcttgtga
     3001 ccctggcttc tacaacctgc agagcgggca aggctgcgag agttgtgact gccatgcttt
     3061 gggctccacc aacgggcaat gtgacatccg caccgggcag tgtgagtgtc agcccggcat
     3121 caccggtcag cactgtgagc gctgtgagac caaccacttt gggtttggac ctgaaggctg
     3181 caaaccttgc gactgtcacc acgaaggatc cctttcgctc caatgtaagg atgacggccg
     3241 ttgtgaatgc agggaaggct tcgtgggcaa tcgctgtgac cagtgtgaag agaactattt
     3301 ctacaatcgg tcttggcctg gctgccaaga gtgtccggct tgttaccggc tggtgaagga
     3361 taaggttgct gagcatcgag tgaaactcca ggagttggag agcctcatag caaacctcgg
     3421 gactggggat gagacggtga cagatcaagc ctttgaggac agactgaagg aagcagagag
     3481 ggaggttaca gacctcctcc gtgaggctca ggaagtcaaa gatgtagacc aaaatctgat
     3541 ggatcgcctt cagagagtaa ataacagtct gcacagccaa atcagccggc tgcacaatat
     3601 ccggaacact atagaagaga cggggatctt ggctgagcga gcgcggtccc gagtggagag
     3661 cacagagcag ctgattgaga tcgcctccag ggagctcgag aaagcaaaaa tggctgccgc
     3721 caatgtgtca atcactcagc cagagtctac aggggaacca aacaacatga ccctcttggc
     3781 agaagaagcc cgaaggcttg cagagcgtca taaacaggaa gctgatgaca ttgtacgagt
     3841 ggcaaagaca gccaacgaga cctcagctga ggcatataat ctgcttttga ggaccctggc
     3901 aggagaaaat caaactgcat tggagattga agagcttaac aggaagtatg aacaagcaaa
     3961 gaacatctct caggacctgg agaagcaggc tgccagagtc catgaggaag ccaagcgagc
     4021 aggtgacaaa gccgtggaga tctatgccag tgtggcccag ctgacccctg tggactcgga
     4081 ggctctagag agtgaagcaa ataaaatcaa gaaagaagct gcagatctgg accgtctgat
     4141 tgaccagaag ctaaaagatt acgaggacct tagggaagac atgcgaggaa aggaacatga
     4201 agtaaagaac cttctagaga aggggaaagc cgaacagcag accgctgacc aactcctagc
     4261 tcgagccgac gctgccaagg ctcttgctga agaagctgct aaaaagggac gcaatacctt
     4321 acaagaagct aacgacattc tcaacaacct gaaagatttt gatagacgag tgaacgataa
     4381 caagacagct gctgaagaag ctctaaggag aattcccgcc atcaaccgga ccatagctga
     4441 agccaatgag aagacaaggg aggcacagct ggcgctgggc aatgcagcag ctgacgccac
     4501 ggaggccaag aacaaagccc acgaggcgga gaggattgcc agtggcgtgc agaagaatgc
     4561 caccagtacc aaggcggatg cggagagaac cttctcggaa gtgacagacc tggataacga
     4621 ggtgaatggc atgttgaggc agctagagga agcggagaat gagctgaaga ggaagcaaga
     4681 tgatgccgac caggacatga tgatggcggg aatggcttca caggctgctc aggaagctga
     4741 acttaatgcc agaaaagcca aaaactctgt cagcagcctc ctcagccaac tgaccgacct
     4801 cttggagcag ctgggacagc tggacaccgt ggacctgaac aagctcaacg agatcgaagg
     4861 ctctctgaac aaagccaaag acgaaatgaa ggtgagcgac ctggacagga aggtgtccaa
     4921 cctggagaac gaggcccgga agcaggaggc agccatcttg gactatgacc gagacatagc
     4981 agagatcata aaggacattc acaacctgga ggacatcaag aagacactac caacaggctg
     5041 ctttaacacc ccgtccatcg agaaacccta gtggtgggag ggctgtaagg cagtgtccct
     5101 gacagggggc cctgtgaggc ctcggtgcct tgacacaaaa attacacttt tcagaccccc
     5161 ccacttctct gctgctctct gtcactgtcc ttttgaccca agaaaagtca gagtttaaag
     5221 agaagcaagt taaacatcct taaccaggaa caaagggttt tgcctaataa agtgtctcct
     5281 ccactcctgt gagcacccta ccggaacttt cccttgtttg cctgaagtca tagcatcttc
     5341 cagtggcata cccacatcac gtgagccttt gtatgccagg gcagacccag ccccctcccc
     5401 tctctcagca ccatcagaac ctatcttagt actcatattt ctatgaagga gatgttcagc
     5461 tcctcaccat agcactgaga tgaccaaata tgtccagtct gcatcttctg cctcctcttt
     5521 gaagcaaaag gaaataaaca tcctgtgcca aaggtattgg tcatttagaa cgttggtagc
     5581 catccatcag acatgctggc tgtttgagca taggccactg agccattacg ggtaacagtg
     5641 tagttacgtg tgggtctctg agagagcatg gctcaaagat gcttacattt ttctcctgtg
     5701 ctaattgact aggaagataa acgttttccc aatcctcagg cagctgatag agagtctgga
     5761 tgggcagctt gcacatacca ctacactagg tagcttttga tagttttata agcaggactc
     5821 agtgcagaag aaacagagat gtgataacca ctcacgtttt ttttccccca aatcttacta
     5881 attcttggag cttcgttagt gtgttagaat tggaacttat tgttagcata tctatcaaaa
     5941 cagtcgtcct ctaaggtctt gaccaatgaa agaaaagcaa atctcctttc cccccatttt
     6001 ctgggaagtg gatgtaaccg gtatgattag gattccataa gtgaatttct ctttctctgt
     6061 tggagagaga tgtgacattt ggcccttagc tccaagtctc ttctgacatt tacattcttt
     6121 caaaacacat cattgtttgc cagatcctgg tggcaaacgc tgctctcagt gtttctcaag
     6181 gccgtggacc ccatctagtt cctgcgcttt gtggctccgc ccactctaag cctttcctct
     6241 gtgtggggag ggaagaacca tgcatggcgt ttcctagtgg gcttctcgac ctctgatcct
     6301 cagctctgtg gttcccttaa gaccacaccg ggacagttcc ctgccacacg cccccttcct
     6361 cctatctacc tgcctctgag attcgtattt agcctttaac actatgcaat tttgtacttt
     6421 gcgtagcggg gggggaaaga aactattatc tgacacactg gtgctattaa ttatttgaaa
     6481 tttatatttt tttgtgtgaa tggatttttg tttatcatga ttatagagta aggagtttat
     6541 gtaaatattc ctggtcctcc tagaacggca ctgtccgctc acgtccctgc tcagttgtcc
     6601 ctctcactgg ccaggaacct gtgcacctcc tcccttccat ccctctctga gtcatgcttg
     6661 gtccccagtg tttgcttcgc ctctgcctgt gtttgcagca tcttcattgt ctaacggatc
     6721 tatcagcctg ctcgcctcca cagcctgacc gaaaagggct ctcttccctg tacctctgac
     6781 catctgagct gcagctccgt gcggttctca atgcctgctc cggagcagta gccaagctga
     6841 cagggtaaag ggatgaggaa agtttgcaga cggaaccttc ccgcatgggt cagttttgta
     6901 agggagcatg tgctgacgga gcacttgagg gcgtcggcac agggctactg atgagagagg
     6961 aggctctgct cagcctggct ccagctctgt tgggcaaacg gagatgacca caaactctca
     7021 gcttggcatc cctgaggttc cgctcttgct cctccgaggc cttttctgct atttcagagg
     7081 cacagcctca ccaagctcag tgctgattgg ctagttcctc tattatgagg tcaccacttt
     7141 aacattctgg tcacagttgc aagaaaatgg ctgacaggcc accagcatcc tttgggtcag
     7201 ctctactcca gcgctggtgg gtggggtgtt ttggtttgtc ttctccatcg ttgttggtat
     7261 atttttaaaa agaattttat ttttaaaaat gaaagttatt tacaagatga taccttacta
     7321 cactcctgcg acacagccat tcattattct attgtatagt tccaataatc tgtattttat
     7381 gtaataaaat ggacaggatg gctgctgtgg aatgccgggt gtcacccaga agagattgtt
     7441 tttatcctac ccccacctcc atggaatttc cctctaactg tggccctttt aaatgtgcct
     7501 tcaccttagc tgtttgcctt aactttacag tcttccccac agggaggtta ataaagcgca
     7561 acacttggcg ttttttatgt ttaaaaagaa aacagtattt tatttataat aaaatctgaa
     7621 tatttgtaac ccttta
//
