LOCUS       XM_003750137            5822 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus laminin subunit beta 1 (Lamb1),
            transcript variant X1, mRNA.
ACCESSION   XM_003750137
VERSION     XM_003750137.5
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_003750137.6.
            
            On Jan 21, 2021 this sequence version replaced XM_003750137.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5822
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5822
                     /gene="Lamb1"
                     /note="laminin subunit beta 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 52
                     ESTs, 11 long SRA reads, 13 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 78 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:298941"
                     /db_xref="RGD:1306311"
     CDS             167..5671
                     /gene="Lamb1"
                     /codon_start=1
                     /product="laminin subunit beta-1 isoform X1"
                     /protein_id="XP_003750185.1"
                     /db_xref="GeneID:298941"
                     /db_xref="RGD:1306311"
                     /translation="MERPLSSLPTFAFSPLYLSRKEDTKKRRAACLPRPPSRAASPRL
                     QGLDMGVLQVFAFGVLALWGTRVCAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTS
                     TCGLHKPEPYCIVSHLQEDKKCFICDSRDPYHETLNPDSHLIENVVTTFAPNRLKIWW
                     QSENGVENVTVQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDC
                     ESSFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLL
                     KITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGF
                     NEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSSSC
                     HFDMAVFLATGNVSGGVCDNCQHNTMGRNCEQCKPFYFQHPERDIRDPNLCEPCTCDP
                     AGSENGGICDGYTDFSVGLIAGQCRCKLHVEGERCDVCKEGFYDLSAEDPFGCKSCAC
                     NPLGTIPGGNPCDSETGYCYCKRLVTGQRCDQCLPQHWGLSNDLDGCRPCDCDLGGAL
                     NNSCSEDSGQCSCLPHMIGRQCNEVESGYYFTTLDHYIYEAEEANLGPGVVVVERRYI
                     QDRIPSWTGPGFVRVPEGAYLEFFIDNIPHSMEYEILIRYEPQLPDHWEKAVITVQRP
                     GRIPTSSRCGNTVPDDDNQVVSLSPGSRYVVLPRPVCFEKGMNYTVRLELPQYTASGS
                     DVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGEVTNSAWETFQRYRCLENSRSVVKTP
                     MTDVCRNIIFSISALIHQAGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAP
                     GTFGFGPNGCKPCDCHLQGSVSAFCDAVTGQCHCFQGIYARQCDRCLPGFWGFPSCQP
                     CQCNGHAEDCDTVTGECLSCQDYTTGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPD
                     SGRQFARSCYQDPVTLQLACVCDPGYIGSRCDGCASGYFGNPSDFGGSCQPCQCHHNI
                     DTTDPEACDKETGRCLKCLYHTEGDHCQFCQHGYYGDALRQDCRKCVCNYLGTVREHC
                     NGSDCHCDKTTGQCSCLPNVIGQNCDRCAPHTWQLASGTGCEPCNCNAVHSFGPSCNE
                     FTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEG
                     VEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIGELTNRTHKFLEKAKALKISGVIG
                     PYRETVDSVEKKVNEIRDILAQSPAAEPLKNIGILFEEAEKLTKDVTEKMAQVEVKLS
                     DTASRSNSTAGELDALQAEAGSLDKTVNELAEQLEFIKNSDIQGALDSITKYFQISLE
                     AEKRVNASTTDPNSTVEQSALTRDRVEDLMLERESQFKEKQEEQARLLDELAGKLQSL
                     DLSAAAEMTCGTHPGADCSESECGGPNCRTDEGEKKCGGPGCGGLVTVAHSAWQKAMD
                     FDRDVLNALAEVEQLSKMVSEAKVRADEAKQNAQDVLLKTNATREKVDRSNEDLRNLI
                     KQIRDFLTEDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVETLSQVEVILQ
                     QSAADIARAELLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI
                     QGTQNLLTSIESETAASEETLTNASQRISKLERNVEELKRKAAQNSGEADYIEKVVYS
                     VKQSADEVKKTLDGELDEKYKKVESLIAQKTEESADARRKAELLQNEAKTLLAQANSK
                     LQLLEDLERKYEDNQKYLEDKAQELVRLEGEVRSLLKDISEKVAVYSTCL"
ORIGIN      
        1 ctccctcggt tcctccctag gcgaaacttt ctaattccct tctttgggcc ggtgggctgc
       61 caggagccac tagaacgctc gcccagccgg gtgaggagaa caaagtactt aagcgacttg
      121 acccccttcc tgggcccagc ccccgcttct gtgggagcgg caggaaatgg aaaggcccct
      181 ctcctctctc ccaacatttg ccttttcccc cctctacctc tccagaaagg aagacacgaa
      241 gaaaagacgg gcagcttgcc tgccgcgtcc tccttcccgt gccgcgtccc ctcgcctgca
      301 aggactggac atgggggtgc tccaggtgtt cgcctttggt gtcctagccc tatggggcac
      361 ccgagtgtgc gctcaggaac cagagttcag ctatggctgc gcggaaggca gctgctaccc
      421 cgccactggc gaccttctca tcggccgagc tcaaaagctc tcagtgacct cgacatgcgg
      481 actgcacaaa ccagagccct actgtattgt cagccacctg caggaggaca agaaatgctt
      541 catatgtgat tcccgggatc cttatcatga gaccctcaat cctgacagcc atctcattga
      601 aaatgtggtc acaacgtttg ctcctaaccg ccttaagatt tggtggcaat cggaaaatgg
      661 tgtggagaac gtaactgtcc aactggacct ggaagcagaa ttccacttca cgcatctcat
      721 catgactttc aagacattcc gtccggcggc catgctgata gagcggtctt ctgactttgg
      781 gaagacttgg ggcgtgtaca gatactttgc ctacgactgt gagagctcat tccccggcat
      841 ttcgactggc cccatgaaga aggtggatga catcatctgt gactctcggt attccgacat
      901 tgagccctca acagaaggag aggtgatatt tcgtgcctta gatcctgctt tcaaaattga
      961 agatccttat agtccaagga tacagaatct attaaaaatc accaacttga gaatcaagtt
     1021 cgtgaaactg cacaccttgg gagataacct tttggactcc agaatggaaa tcagagagaa
     1081 gtactattac gctgtttatg atatggtggt tcgagggaac tgcttctgct atggtcatgc
     1141 cagtgaatgt gcccccgtgg atggattcaa cgaagaagtg gaaggaatgg ttcatgggca
     1201 ctgcatgtgc agacacaaca ctaaaggctt gaactgtgag ctgtgcatgg atttctacca
     1261 cgatttgccg tggagacctg ccgaaggtcg gaacagtaac gcctgcaaaa agtgtaactg
     1321 caacgaacat tccagctcgt gtcactttga catggcggtc ttcctggcta ccggcaatgt
     1381 cagcggggga gtgtgtgata actgtcagca caacaccatg gggcgcaact gcgagcagtg
     1441 caaacccttc tacttccagc accctgagag ggacatccgg gaccccaatc tctgcgaacc
     1501 atgtacctgt gatccagctg gttctgagaa tggagggatc tgtgacggtt acactgattt
     1561 ttctgtgggt ctcattgctg gtcagtgtcg gtgcaaattg cacgtggagg gagagcgctg
     1621 cgacgtctgt aaagaaggct tctatgacct gagtgctgag gacccgttcg gttgtaaatc
     1681 gtgtgcttgc aatcctctgg gaacaattcc tggtgggaat ccttgtgact ctgagaccgg
     1741 ttactgctac tgtaaacgtc tggtgacagg acagcgctgt gaccagtgcc tgccgcagca
     1801 ctggggctta agcaatgact tggacggatg tcgaccctgt gactgtgacc ttggaggggc
     1861 attgaacaat agctgctccg aggactccgg ccagtgctcc tgcctgcccc acatgattgg
     1921 gcggcagtgt aacgaggtgg agtctggcta ctacttcacc accctggacc attacatcta
     1981 cgaagctgag gaagccaatc ttgggcctgg ggtcgttgtg gtggagaggc ggtacattca
     2041 ggaccgcatt ccttcctgga caggacctgg cttcgtccgg gtgcccgagg gggcttactt
     2101 ggagtttttc attgacaaca taccacattc catggagtat gaaatcctaa ttcgctatga
     2161 accacagctg ccggaccact gggagaaagc tgtcatcacc gtacagcggc cggggaggat
     2221 tccaaccagc agccgatgtg gtaacactgt tcctgatgat gacaaccagg tggtgtcctt
     2281 gtcaccgggc tcaagatacg ttgtcctccc tcgcccagta tgctttgaaa aggggatgaa
     2341 ctacaccgtg cggttggagc tgccccagta tacggcatct ggcagtgacg tggagagccc
     2401 ttatactctc attgactcgc ttgttctcat gccctactgt aagtcgctgg acatcttcac
     2461 tgttggaggc tcaggagatg gggaggtcac caacagtgcc tgggaaacct tccagcgcta
     2521 caggtgtctg gagaacagcc ggagtgtggt gaaaacacct atgacagatg tctgcagaaa
     2581 catcatcttc agcatttctg ccttgatcca ccaggcaggc ctcgcttgtg aatgtgaccc
     2641 tcagggatct ctgagttctg tgtgtgaccc caatggaggc cagtgccagt gccgccctaa
     2701 cgtggtcgga agaacctgca atcggtgtgc acctggtacc ttcgggtttg gccccaacgg
     2761 atgcaaacct tgtgactgtc atctacaagg atctgtcagt gccttctgtg acgcagtcac
     2821 tggccagtgc cactgtttcc agggcatata tgctcggcag tgtgaccgat gtctccctgg
     2881 gttttggggc tttcccagct gccagccctg ccagtgtaat ggccatgctg aagattgtga
     2941 cacagtgacc ggggagtgtc tgagctgtca ggactacacc acgggccaca actgcgaaag
     3001 gtgtctggct ggttactatg gtgatcccat cattgggtca ggagaccact gtcgcccttg
     3061 tccttgtcct gatggtcctg acagtggacg ccagtttgcc aggagctgtt atcaagaccc
     3121 tgtcacgctc cagcttgcat gtgtttgcga tcctgggtac attggctcca gatgtgatgg
     3181 ctgtgcctct gggtattttg gcaatccctc ggactttggg ggttcatgtc agccctgtca
     3241 gtgtcaccac aacattgaca ctaccgaccc agaagcctgt gacaaggaga ctgggagatg
     3301 tctcaagtgc ctgtaccaca cagaggggga ccattgccag ttttgccagc atgggtacta
     3361 cggcgatgct cttcgacaag actgtagaaa gtgtgtctgc aattacctgg gcacagtgag
     3421 ggagcattgt aacggctctg actgccattg cgacaaaacc accggtcagt gctcgtgtct
     3481 tccgaatgtg atcgggcaga actgtgatcg gtgtgcaccc cacacctggc agctggccag
     3541 cgggactggc tgcgagccgt gcaattgcaa tgctgtgcat tccttcgggc catcctgcaa
     3601 tgagttcaca gggcagtgcc agtgcatgcc aggctttgga ggccgaacct gcagcgagtg
     3661 ccaggagctc ttctggggag accccgatgt ggagtgccga gcctgtgact gtgatcccag
     3721 gggcattgag acaccgcagt gtgaccagtc cacgggccag tgtgtctgtg tggagggtgt
     3781 tgagggtcca cgctgtgaca agtgcaccag agggtactcc ggggtcttcc ctgactgcac
     3841 accctgccac cagtgctttg ctctctggga tgtgatcatt ggtgagctga ccaacaggac
     3901 ccacaaattc ctggagaaag ccaaggcttt gaaaatcagt ggtgtgattg gtccctaccg
     3961 agagaccgtg gactctgtgg agaagaaagt caatgaaata agagacatcc tggcccagag
     4021 cccagcagcg gaaccactga aaaacattgg cattctcttt gaggaggcag agaaattaac
     4081 caaagatgtc acagaaaaga tggctcaagt agaagtgaaa ttatctgaca cagcttcacg
     4141 gagtaacagc acagccggag agctggacgc actgcaggca gaagcaggga gccttgacaa
     4201 gaccgtgaac gagctggcag aacagctaga atttatcaaa aactccgata ttcagggtgc
     4261 cttagacagt atcaccaagt atttccagat ctctcttgag gcagaaaaga gggtgaacgc
     4321 ctccaccaca gaccccaaca gcactgtgga gcagtcagcc ctcacccgag acagagtgga
     4381 agatctgatg ttggagcgag agtctcagtt caaggaaaag caggaggaac aggcgcgcct
     4441 tctggatgaa ctggcgggca aactgcaaag tctagacctg tcggctgctg cagagatgac
     4501 ctgtggaacg catccagggg ctgactgttc tgaaagtgaa tgtggtggcc ccaactgcag
     4561 aactgacgaa ggagagaaga agtgtggagg gcctggctgt ggtggtctgg tcactgtggc
     4621 ccatagtgcc tggcagaaag ccatggattt tgaccgtgat gtcctgaatg ccctggctga
     4681 agtagaacag ctctccaaga tggtctctga agcaaaagtg agagcggacg aggctaagca
     4741 gaatgctcag gatgtcctgt tgaaaacaaa tgccaccaga gagaaagtgg acaggagcaa
     4801 tgaggacctg aggaacctca tcaagcaaat cagagacttt ctgacggagg acagcgctga
     4861 tctggacagt attgaagccg ttgcgaacga agtactgaag atggaaatgc ctagcacccc
     4921 acagcagttg caaaacctaa cagaagacat ccgggaacga gttgaaaccc tttcccaagt
     4981 agaagttatt ttgcagcaga gtgctgctga cattgccaga gctgagctgt tgctggaaga
     5041 agctaagaga gcaagcaaaa gtgcaacaga tgttaaggtc actgcagaca tggtaaagga
     5101 ggcgttggaa gaagcagaaa aggcccaggt tgcagcagag aaggcgatta aacaagctga
     5161 tgaggatatc caggggaccc agaacctgct aacatcgatt gaatctgaga cagcagcgtc
     5221 tgaggaaacc ctgaccaatg cctcccagcg catcagcaag cttgagagga atgtggaaga
     5281 gcttaagcgt aaagctgccc agaactctgg ggaggcagac tatattgaaa aagtcgtata
     5341 tagtgtaaaa cagagtgcag acgaggttaa gaagactcta gatggcgaac ttgatgaaaa
     5401 atataagaag gtagagagtt taattgccca aaaaactgaa gagtcagcag atgccaggag
     5461 gaaagctgag ctgctacaaa atgaagcaaa aacactcctg gcccaagcca acagcaaact
     5521 tcagctgtta gaagacttag aaaggaagta tgaggacaat caaaagtact tagaagataa
     5581 agctcaagaa ctggtgcgac tggaaggaga ggtgcgctca ctccttaagg acataagtga
     5641 gaaagttgcc gtttacagca cctgcttata acagaggatg gggctgtagg gtggctcagt
     5701 gaccaaagta aacatgcgca aactgctgcc tcgacctaca gataactcat cctcatttaa
     5761 tgtctttaac caccttcttt tgtatggagc taaataaaat acattggttt tatataaaca
     5821 ta
//
