LOCUS       NM_001108237            9955 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus laminin subunit alpha 1 (Lama1), mRNA.
ACCESSION   NM_001108237 XM_001054302 XM_237536
VERSION     NM_001108237.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 9955)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   2  (bases 1 to 9955)
  AUTHORS   Soteriou,D., Iskender,B., Byron,A., Humphries,J.D.,
            Borg-Bartolo,S., Haddock,M.C., Baxter,M.A., Knight,D.,
            Humphries,M.J. and Kimber,S.J.
  TITLE     Comparative proteomic analysis of supportive and unsupportive
            extracellular matrix substrates for human embryonic stem cell
            maintenance
  JOURNAL   J Biol Chem 288 (26), 18716-18731 (2013)
   PUBMED   23658023
REFERENCE   3  (bases 1 to 9955)
  AUTHORS   Artus,J., Piliszek,A. and Hadjantonakis,A.K.
  TITLE     The primitive endoderm lineage of the mouse blastocyst: sequential
            transcription factor activation and regulation of differentiation
            by Sox17
  JOURNAL   Dev Biol 350 (2), 393-404 (2011)
   PUBMED   21146513
REFERENCE   4  (bases 1 to 9955)
  AUTHORS   Castets,P., Bertrand,A.T., Beuvin,M., Ferry,A., Le Grand,F.,
            Castets,M., Chazot,G., Rederstorff,M., Krol,A., Lescure,A.,
            Romero,N.B., Guicheney,P. and Allamand,V.
  TITLE     Satellite cell loss and impaired muscle regeneration in
            selenoprotein N deficiency
  JOURNAL   Hum Mol Genet 20 (4), 694-704 (2011)
   PUBMED   21131290
REFERENCE   5  (bases 1 to 9955)
  AUTHORS   Bergerat,A., Decano,J., Wu,C.J., Choi,H., Nesvizhskii,A.I.,
            Moran,A.M., Ruiz-Opazo,N., Steffen,M. and Herrera,V.L.
  TITLE     Prestroke proteomic changes in cerebral microvessels in
            stroke-prone, transgenic[hCETP]-Hyperlipidemic, Dahl salt-sensitive
            hypertensive rats
  JOURNAL   Mol Med 17 (7-8), 588-598 (2011)
   PUBMED   21519634
  REMARK    GeneRIF: Data confirmed aquaporin-4 and laminin-alpha1 induction in
            cMVs.
REFERENCE   6  (bases 1 to 9955)
  AUTHORS   Keely,P.J., Wu,J.E. and Santoro,S.A.
  TITLE     The spatial and temporal expression of the alpha 2 beta 1 integrin
            and its ligands, collagen I, collagen IV, and laminin, suggest
            important roles in mouse mammary morphogenesis
  JOURNAL   Differentiation 59 (1), 1-13 (1995)
   PUBMED   7589890
REFERENCE   7  (bases 1 to 9955)
  AUTHORS   Utani,A., Nomizu,M., Timpl,R., Roller,P.P. and Yamada,Y.
  TITLE     Laminin chain assembly. Specific sequences at the C terminus of the
            long arm are required for the formation of specific double- and
            triple-stranded coiled-coil structures
  JOURNAL   J Biol Chem 269 (29), 19167-19175 (1994)
   PUBMED   8034675
REFERENCE   8  (bases 1 to 9955)
  AUTHORS   Schuger,L., Varani,J., Killen,P.D., Skubitz,A.P. and Gilbride,K.
  TITLE     Laminin expression in the mouse lung increases with development and
            stimulates spontaneous organotypic rearrangement of mixed lung
            cells
  JOURNAL   Dev Dyn 195 (1), 43-54 (1992)
   PUBMED   1292752
REFERENCE   9  (bases 1 to 9955)
  AUTHORS   Schuger,L., Skubitz,A.P., O'Shea,K.S., Chang,J.F. and Varani,J.
  TITLE     Identification of laminin domains involved in branching
            morphogenesis: effects of anti-laminin monoclonal antibodies on
            mouse embryonic lung development
  JOURNAL   Dev Biol 146 (2), 531-541 (1991)
   PUBMED   1907584
REFERENCE   10 (bases 1 to 9955)
  AUTHORS   Engvall,E., Earwicker,D., Haaparanta,T., Ruoslahti,E. and
            Sanes,J.R.
  TITLE     Distribution and isolation of four laminin variants; tissue
            restricted distribution of heterotrimers assembled from five
            different subunits
  JOURNAL   Cell Regul 1 (10), 731-740 (1990)
   PUBMED   2099832
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1 and BE108973.1.
            
            On Aug 24, 2019 this sequence version replaced NM_001108237.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB425340.1, AB425341.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-582               JAXUCZ010000009.1  115139548-115140129
            583-753             JAXUCZ010000009.1  115161343-115161513
            754-866             JAXUCZ010000009.1  115161803-115161915
            867-1109            JAXUCZ010000009.1  115182689-115182931
            1110-1289           JAXUCZ010000009.1  115183951-115184130
            1290-1379           JAXUCZ010000009.1  115185362-115185451
            1380-1497           JAXUCZ010000009.1  115186582-115186699
            1498-1676           JAXUCZ010000009.1  115188706-115188884
            1677-1782           JAXUCZ010000009.1  115189509-115189614
            1783-1943           JAXUCZ010000009.1  115190434-115190594
            1944-2084           JAXUCZ010000009.1  115191588-115191728
            2085-2258           JAXUCZ010000009.1  115192789-115192962
            2259-2360           JAXUCZ010000009.1  115193830-115193931
            2361-2572           JAXUCZ010000009.1  115194291-115194502
            2573-2684           JAXUCZ010000009.1  115195257-115195368
            2685-2795           JAXUCZ010000009.1  115197548-115197658
            2796-2923           JAXUCZ010000009.1  115202274-115202401
            2924-3010           JAXUCZ010000009.1  115204290-115204376
            3011-3222           JAXUCZ010000009.1  115205098-115205309
            3223-3329           JAXUCZ010000009.1  115207286-115207392
            3330-3510           JAXUCZ010000009.1  115207679-115207859
            3511-3647           JAXUCZ010000009.1  115208607-115208743
            3648-3884           JAXUCZ010000009.1  115209888-115210124
            3885-4028           JAXUCZ010000009.1  115211446-115211589
            4029-4208           JAXUCZ010000009.1  115212488-115212667
            4209-4394           JAXUCZ010000009.1  115213480-115213665
            4395-4522           JAXUCZ010000009.1  115214142-115214269
            4523-4643           JAXUCZ010000009.1  115215393-115215513
            4644-4781           JAXUCZ010000009.1  115216691-115216828
            4782-4903           JAXUCZ010000009.1  115218464-115218585
            4904-4990           JAXUCZ010000009.1  115220027-115220113
            4991-5184           JAXUCZ010000009.1  115220368-115220561
            5185-5327           JAXUCZ010000009.1  115220907-115221049
            5328-5417           JAXUCZ010000009.1  115223225-115223314
            5418-5529           JAXUCZ010000009.1  115224226-115224337
            5530-5692           JAXUCZ010000009.1  115225090-115225252
            5693-5900           JAXUCZ010000009.1  115230080-115230287
            5901-6017           JAXUCZ010000009.1  115230453-115230569
            6018-6181           JAXUCZ010000009.1  115230688-115230851
            6182-6317           JAXUCZ010000009.1  115233413-115233548
            6318-6411           JAXUCZ010000009.1  115234536-115234629
            6412-6528           JAXUCZ010000009.1  115235976-115236092
            6529-6711           JAXUCZ010000009.1  115237717-115237899
            6712-6866           JAXUCZ010000009.1  115238159-115238313
            6867-7010           JAXUCZ010000009.1  115239938-115240081
            7011-7144           JAXUCZ010000009.1  115241671-115241804
            7145-7295           JAXUCZ010000009.1  115243191-115243341
            7296-7420           JAXUCZ010000009.1  115244131-115244255
            7421-7571           JAXUCZ010000009.1  115246762-115246912
            7572-7716           JAXUCZ010000009.1  115248167-115248311
            7717-7858           JAXUCZ010000009.1  115248749-115248890
            7859-7973           JAXUCZ010000009.1  115248977-115249091
            7974-8144           JAXUCZ010000009.1  115249262-115249432
            8145-8296           JAXUCZ010000009.1  115250347-115250498
            8297-8482           JAXUCZ010000009.1  115251199-115251384
            8483-8618           JAXUCZ010000009.1  115252709-115252844
            8619-8731           JAXUCZ010000009.1  115254081-115254193
            8732-8921           JAXUCZ010000009.1  115255369-115255558
            8922-9080           JAXUCZ010000009.1  115256457-115256615
            9081-9234           JAXUCZ010000009.1  115257113-115257266
            9235-9368           JAXUCZ010000009.1  115258838-115258971
            9369-9591           JAXUCZ010000009.1  115262481-115262703
            9592-9938           JAXUCZ010000009.1  115263273-115263619
            9939-9955           BE108973.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..9955
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q38"
     gene            1..9955
                     /gene="Lama1"
                     /note="laminin subunit alpha 1"
                     /db_xref="GeneID:316758"
                     /db_xref="RGD:1307207"
     exon            1..582
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     CDS             501..9752
                     /gene="Lama1"
                     /note="laminin-1; laminin, alpha 1"
                     /codon_start=1
                     /product="laminin subunit alpha-1 precursor"
                     /protein_id="NP_001101707.2"
                     /db_xref="GeneID:316758"
                     /db_xref="RGD:1307207"
                     /translation="MRGSGTGVALLVLLASVLWVTVRSQQRGLFPAILNLATNAHISA
                     NATCGEKGPEMFCKLVEHVPGRPVRHAQCRVCDGNSTNPRERHPITHAIDGTNNWWQS
                     PSIQNGREYHWVTVTLDLRQVFQVAYVIIKAANAPRPGNWILERSVDGVKFRPWQYYA
                     VSDTECLTRYKITPRRGPPTYRADNEVICTSYYSKLVPLEHGEIHTSLINGRPSADDP
                     SPQLLEFTSARYIRLRLQRIRTLNADLMTLSHRDLRDLDPIVTRRYYYSIKDISVGGM
                     CICSGHASSCPWDEEAKQLQCQCEHNTCGESCDRCCPGFHQQPWRPGTISSSNQCEEC
                     NCHNKAKDCYYDNNVAKERKSLNTAGQYSGGGVCINCLQNTTGINCETCIDQYYRPHK
                     VSPYEDQPCRPCDCDPVGSLSSVCIKDDLHADLANGKWPGQCPCRKGYAGDKCDRCQF
                     GYRGFPNCVPCDCSTVGSVNEDPCTEPCLCKKNVEGENCDRCKPGFYNLKERNPEGCS
                     ECFCFGVSDVCDSLTWSVSQVTNMSGWLVTDLISPNKIRSQQDALGRHRQISINNTAV
                     MHRFTSPYYWAAPEAYLGNKLTAFGGFLKYTVSYDIPVETVDSNLMSHADVIIKGNGL
                     TISTRAEGLSLQPYEEYFNVVRLVPENFRDFNTRREIDRDQLMTVLANVTHLLIRANY
                     NSAKMALYRLDSVSLDIASPNAIDLVVAADVEHCECPQGYTGTSCEACLPGYYRVDGI
                     LFGGICQPCECHGHSSECDIHGICSGCTHNTTGDHCEQCLPGFYGTPSRGTPGDCQPC
                     ACPLSIDSNNFSPTCHLTDREEVVCDQCAPGYSGAWCERCADGYYGNPTVPGGTCVPC
                     NCSGNVDPLEAGHCDSVTGECLKCLWNTDGAHCERCADGFYGDAVTAKNCRACNCHEN
                     GSLSGICHLETGLCDCKPYVTGQQCDQCLPGYYGLDTGLGCVPCNCSGEGSISDNCTE
                     EGQCHCVPGVSGKQCDQCSHGFYAFQNGGCTPCDCAHTQNNCDPDSGECLCPPHTHGL
                     KCEQCEEAFWGLDPEQGCQACNCSVVGSTSPQCDVLSGQCSCKEGFGGQSCHQCSLGY
                     RSFPDCVPCDCDLRGTLADTCDLEQGLCSCTEDSGTCSCKENVLGPQCDKCRAGTFAL
                     RADNPLGCSPCFCFGLSQLCSELEGYVRAPITLASDQPILHVVSQSNLKGTTEGVHFQ
                     PPDTLLDAEAVRQHIYAEPFYWRLPKQFQGDQLLAYGGKLQYTVAFYSTLGTGTSNYE
                     PQVLIKGGRTRKHIIYMDAPAPENGVRQDYEVGMKEEFWKYFNSVSEKHVTHSDFMSV
                     LSNIEYILIKASYGQGLQQSRIANISMEVGRKAVEPAPEGKVALQLELCVCPPGTAGH
                     SCQDCAPGYHRGKLPESSGRGPRPLLAPCVPCNCNNHSDVCDPETGKCLNCRDHTAGD
                     HCELCTAGYYGKVIGLPGDCTPCTCPHHPPFSFSPTCVLEGDSGFWCDACLPGYEGQY
                     CERCSAGYHGNPRAAGGSCQKCDCNPQGSVHSDCDRASGQCVCKPGATGLHCEECLPR
                     HILMESHCVSCDDECVGALLNDLDSIGDAVLSLNLAGVSLAPYGTLENLENTTKYFQG
                     YLLEENAKKVQAEIQLGGIEEQTENLQKELARVLRSHQQVNTAMERTSNRSQALATFL
                     EQLHRNIKEITEKVATLNQTTGEDFQPPVSALQSLHQNISSLLALIKKRNFTEMRQNA
                     TLELKAAKDLLSRIQKRFQKPQEKLKALKEASSLLSNHIADLQAAEELLREAGSKTQE
                     SSLLLLLVKANLKDFREKKLHVQEEQNLTSKLIAQGREWVDAARTHAAAAQDTLTQLE
                     HHRDELLLWASKIRSHVDDLVMQMSKRRARDLVHRAEQHASELQSAAEALDRDLENVR
                     NVSLNATSAVHVHTNIQTLTEEAESLAADAHKTANKTSLISESLAPRGKAVLQRSSRF
                     VKESVSTRKKQQGITLKLDELKNLTSQFQERVDNITRQANDSLTVLRESPGGMREKSR
                     KVKELAVAANETAARTLEDMLGLSLRVFNTSEDLSRVNATVQETKDLLHNSTMTTILA
                     GRKMRDMEMQANLLFDRLKPLKMLEENLSRNLSEIKLLISRARKQAASIKVAVSADRD
                     CIRAYQPQISSTNYNTLLLNVKTQEPDNLLFYLGSSSSSDFLAVEMRRGKAAFLWDLG
                     SGSTRLEFPDVSINNDKWHSIYITRFGNMGSLSVKEASAAEDPPVRTSKSPGLANVLD
                     INNSTLMFVGGLGGQIKKSPAVKVTHFKGCMGEAFLNGKSIGLWNYIEREGKCNGCFG
                     SSQNEDASFHFDGSGYAVVEKALRPTVTQIIILFSTFSPNGLLFYLASNGTKDFLSIE
                     LLRGRVKVMVDLGSGPLTLMTDRRYNNGTWYKIAFQRNRKQGLLAVFDAYDTSDKETK
                     QGETPGAASDLNRLEKDLIYVGGLPHSKAVRKGVSSRSYVGCIKNLEISRSTFDLLRN
                     SYGVRKGCTLEPIQSVSFLKGGYMEMPPKSLSPESSLLATFATKNSSGVILAALGKDA
                     EKAGASQAHVPFFSILLIEGRIEVHINSGDGTSLRKALLHAPTGSYSDGQEHSISVVR
                     NRRVITVQLDENSPVEMKLGPLTEGRTINISNLYIGGLPEGKGTPMIRMRTSFHGCIK
                     NVVIDAQLLDFTRAAGSEQVELDTCLLAEEPTQGLHREHGELPPEPPTLPEPELCAVD
                     TAPGYVAGAHQFGLSQNSHLVLPFNQSDVRKRLQVQLNIRTFASSGLIYYVAHQNQMD
                     YAVLQLHEGRLNFMFDLGKGRTKVSHPALLSDGKWHTVKTEYIKRKAFMTVDGQESPS
                     VTVVGNATTLDVERKLYLGGLPAHYRARSIGTITHSIPACIGDVTVNSQQLDKDRPAS
                     AFAVDRCYAVAQEGTFFEGSGYAALVKEGYKVRLDLNITLEFRTSSKNGVLLGISSAK
                     VDAIGLEIVDGKVSFHVNNGAGRITATYKPRATRTLCDGKWHTLHAHKSRHRIVLTVD
                     GDAVRAESPHTHSTSADTNDPIYVGGYPAHVKQNCLSSRASFRGCVRNLELSRGSQVQ
                     SLDLSRAFDLHGVFPHSCPGPEP"
     exon            583..753
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            754..866
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1109
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1289
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1379
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1497
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1676
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1782
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1943
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            1944..2084
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2085..2258
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2259..2360
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2361..2572
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2684
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2685..2795
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2796..2923
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            2924..3010
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3222
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            3223..3329
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            3330..3510
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            3511..3647
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            3648..3884
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            3885..4028
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4029..4208
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4209..4394
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4395..4522
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4523..4643
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4644..4781
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4782..4903
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4904..4990
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            4991..5184
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            5185..5327
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            5328..5417
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            5418..5529
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            5530..5692
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            5693..5900
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            5901..6017
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6018..6181
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6182..6317
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6318..6411
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6412..6528
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6529..6711
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6712..6866
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            6867..7010
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7011..7144
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7145..7295
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7296..7420
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7421..7571
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7572..7716
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7717..7858
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7859..7973
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            7974..8144
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            8145..8296
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            8297..8482
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            8483..8618
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            8619..8731
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            8732..8921
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            8922..9080
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            9081..9234
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            9235..9368
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            9369..9591
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
     exon            9592..9939
                     /gene="Lama1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atatttctgc gacagattgg ctaagaccgc acagccccaa caggcagaaa agggtcaaca
       61 gggcaaatac tttcttggaa ttcactctca gggtcagact taacagaaac tcacttcttc
      121 ctgggcactg tctctccacc ttcctctcca ttgaacccct aatgctgaag cagctcaccc
      181 caactggagt agagggtcag agtaccacct aggagaggca ccccaccacc acaggcagga
      241 caggccccct tgaggaggga cccctaggaa aaacacgggc agggcggggc tccccctgga
      301 ggacagacct gggcgcagcg gggcgccctt gggggaggtc ccgggtagga gaggggcggg
      361 gcgcggccag gccggcgggg gtgtgtccga agggcctgcg taccaggcca gggtcgggct
      421 gggaggacca cacttgcgcg gtgcctgtga acgagcgtgg tcgagacctt ccttggagcg
      481 cagggagcga cgacggcgtc atgcgcggca gcggtacggg agtcgcgctc ttggtgctcc
      541 tggcctcggt gctctgggtc accgtgcgga gccagcagcg aggcttgttc cctgccattc
      601 tcaacctggc caccaatgcc cacatcagtg ccaatgctac ctgtggagag aaggggcctg
      661 agatgttctg caagctcgtg gagcacgtgc cgggccggcc tgttcgacac gcccagtgcc
      721 gggtctgtga tggtaacagt acaaatccta gagagcgcca cccgataacc cacgcaatag
      781 acggcaccaa taactggtgg caaagcccca gcattcagaa tgggagagag tatcactggg
      841 tcaccgtcac cctggactta cggcaggtct ttcaagttgc gtatgtcatc attaaagctg
      901 ccaatgcccc tcggcctgga aactggattt tggagcgctc cgtggatggt gtcaagttta
      961 gaccctggca gtactatgca gtcagtgaca cagagtgtct gacgcgctac aaaataactc
     1021 cacggcgggg acctcccacc tacagagctg acaacgaagt gatctgcacc tcgtattatt
     1081 ctaaactggt gccacttgaa catggagaga tccacacatc actcatcaat ggcaggccca
     1141 gtgctgatga cccctcgccc cagttgctgg aattcacctc agcacggtac atacgccttc
     1201 gtctgcagcg catcagaaca ctcaatgcag acctcatgac ccttagccac cgggacctca
     1261 gagacctcga cccgattgtc acaagacgtt attactactc gataaaagac atctccgttg
     1321 gaggcatgtg catttgctcc ggccatgcta gcagctgccc ctgggatgaa gaagcaaagc
     1381 aacttcagtg tcagtgtgaa cataatacat gtggtgagag ctgtgacagg tgctgtcccg
     1441 gcttccatca gcagccctgg aggcccggaa ccatttcctc cagtaaccag tgtgaagaat
     1501 gtaactgtca caacaaagcc aaagattgtt actatgacaa caatgttgca aaggagagga
     1561 aaagccttaa cactgccggg cagtacagcg gaggaggagt ttgtatcaac tgcttgcaga
     1621 acaccacagg gatcaactgt gaaacctgca ttgaccagta ctacagacct cacaaagtat
     1681 ctccgtatga ggaccagcct tgccgtccct gtgactgtga cccggtgggg tctctgagtt
     1741 ctgtctgtat caaggatgac ctccacgccg acttagccaa cgggaagtgg ccgggtcagt
     1801 gtccatgtag gaaaggttat gcaggagaca aatgtgaccg ctgccagttt ggctaccggg
     1861 gtttcccgaa ttgcgtcccc tgtgactgca gcaccgttgg cagcgtgaac gaggacccat
     1921 gcacagagcc atgtctttgt aagaaaaatg ttgagggaga gaattgtgat cgctgcaaac
     1981 caggattcta taacttgaag gaaagaaacc ccgagggctg ctcggagtgc ttctgctttg
     2041 gtgtctccga tgtctgtgac agcctcacat ggtctgtcag tcaggtgacc aatatgtcag
     2101 ggtggttggt caccgacttg atcagcccaa ataagatccg gtctcagcag gatgccctgg
     2161 gcaggcaccg tcagatcagc atcaacaaca cggcggtcat gcacagattt acttcccctt
     2221 attactgggc agctcctgag gcctaccttg gaaacaagct gacagcattt ggtgggttcc
     2281 taaaatacac agtgtcttac gacatccctg tggagacggt ggacagtaat ctcatgtctc
     2341 atgctgacgt catcatcaag ggaaatgggc tcactataag cacacgggct gagggcctgt
     2401 ccttgcaacc ctacgaggaa tacttcaatg tggttagact tgtgcctgag aacttccggg
     2461 actttaatac cagaagggag attgaccgtg accagctgat gactgtcctg gccaatgtga
     2521 ctcatctctt gattagagcc aactataatt ctgctaaaat ggcgctgtat agattggatt
     2581 ctgtctctct ggacatagca agccctaatg ctatagacct ggtagttgct gctgatgtgg
     2641 agcactgcga atgtccccaa ggctacacag ggacctcctg tgaggcctgc ctccccggct
     2701 attatcgagt agatgggata ctctttggag gaatctgtca gccctgcgaa tgccacggcc
     2761 actcatctga gtgtgacatt catggaattt gctctgggtg tacacacaac accacagggg
     2821 atcactgtga gcagtgcctg cctggcttct atgggacacc ttcacgtggg accccagggg
     2881 actgccagcc ttgtgcctgc cctctctcca ttgactccaa caatttcagc cctacctgcc
     2941 acctcaccga cagagaggaa gtggtctgcg accagtgtgc cccaggttac tcaggagcct
     3001 ggtgtgagag atgtgcagat ggttactatg gaaacccaac cgtgccaggg ggaacctgtg
     3061 taccatgcaa ctgcagtggc aatgttgatc ccctggaggc tggccactgt gactctgtca
     3121 ccggggaatg cctgaagtgc ttgtggaaca cagacggtgc ccactgtgag aggtgtgcag
     3181 atggcttcta tggagacgca gtgactgcca aaaactgccg agcctgtaac tgccatgaaa
     3241 atggctccct ttctggcatc tgccatctgg aaactggact gtgtgattgc aaaccttacg
     3301 tgacaggaca gcagtgcgac cagtgcctgc ctggctatta tgggttggac acgggacttg
     3361 gctgtgtgcc ctgtaactgc agcggggaag gctccatatc tgacaactgc acggaggaag
     3421 gccagtgtca ctgtgtacca ggtgtatctg gaaaacagtg tgaccagtgt tcacacggct
     3481 tctatgcatt ccagaatggc ggctgtacac cctgtgactg tgctcatact cagaataact
     3541 gtgaccccga ttctggagag tgtctctgcc cacctcacac tcacggtctg aagtgcgagc
     3601 aatgtgaaga ggcattctgg gggctggacc cggagcaggg gtgccaggct tgcaattgta
     3661 gtgtggtggg ctccacaagt ccccagtgtg atgttctctc tggccaatgt tcctgcaaag
     3721 aagggtttgg cgggcagagc tgccatcagt gttccttggg ctacaggagt tttcctgact
     3781 gtgttccctg tgactgtgac ctgagaggga cactggctga cacctgtgac ctggaacagg
     3841 gtctctgcag ctgcacagag gacagcggca cctgctcctg caaggagaat gtcctgggac
     3901 cccagtgcga taaatgccga gctggcacct ttgccttgcg agctgacaac cccctaggct
     3961 gcagcccctg tttctgcttt ggtctatcac agctctgctc ggagttggag ggttatgtgc
     4021 gggctcctat aaccctagcc tccgatcagc ccatcctgca tgtggtttca cagagcaacc
     4081 tcaagggcac aactgaaggg gtgcatttcc agcctccgga caccttgctg gatgcagagg
     4141 ctgtccgcca gcacatctat gcagagccat tttactggcg gctaccgaag cagttccagg
     4201 gagatcagct cttggcctat ggtgggaaac tgcagtatac cgtggctttc tactccaccc
     4261 tcggcaccgg tacatccaat tatgagcctc aagtcctcat caaaggaggt cggaccagga
     4321 agcacatcat ttatatggat gccccagcac cagagaacgg agtgagacag gactatgaag
     4381 tggggatgaa agaggagttt tggaaatatt ttaactctgt gtctgagaaa catgtcacac
     4441 actccgattt tatgtctgtt ctcagcaata ttgagtatat cctcatcaaa gcatcatacg
     4501 gccaaggact gcagcaaagc agaattgcca acatctccat ggaggttggc aggaaggctg
     4561 ttgagccggc ccctgagggc aaggtggcac tgcagttgga gctctgtgtc tgtcctcctg
     4621 gcaccgctgg acactcctgt caggactgtg ctcctgggta ccacagaggg aagctcccag
     4681 aaagcagtgg taggggaccc cgccctctgt tggctccctg cgtgccctgc aactgcaaca
     4741 accacagtga tgtctgtgac cccgaaactg gaaagtgtct gaactgcagg gaccacacag
     4801 ccggcgacca ctgcgagctg tgcactgctg gctactatgg aaaagtgatt gggttgcctg
     4861 gagactgtac cccatgcacc tgtcctcatc accctccttt cagtttcagc cccacttgtg
     4921 tcttggaagg tgacagtggt ttctggtgtg atgcctgtct ccccggctat gagggacagt
     4981 actgcgaaag gtgctctgcg ggctatcacg gcaaccctcg agcagcgggt ggcagctgcc
     5041 agaagtgtga ctgcaacccc caaggctctg tccacagtga ctgtgaccgt gcatcggggc
     5101 agtgtgtctg caagccagga gctacgggac tccactgtga ggaatgcctg ccgagacaca
     5161 tcctgatgga gagccactgt gtgtcttgtg atgatgaatg tgtgggtgct ttgctgaacg
     5221 acctggattc tattggtgat gctgtcctgt ctttgaacct cgcgggtgtt tcccttgctc
     5281 cgtacggaac tctggaaaat ctggaaaata caactaaata tttccagggg tatttgctag
     5341 aggaaaacgc caagaaggtg caggcagaaa tccagcttgg aggtatcgaa gaacagacag
     5401 aaaatctgca aaaggagctc gccagagtgt tgagaagcca tcagcaggtg aacacagcaa
     5461 tggaaagaac ctccaatagg agtcaggccc tggccacgtt cctcgagcag cttcacagaa
     5521 acatcaaaga aatcacggag aaggtggcaa cattgaatca gaccacaggt gaagatttcc
     5581 agccgcccgt ttctgccctt cagagcctgc accagaacat ttcgtctttg ctggcactta
     5641 taaagaaaag gaatttcaca gagatgcggc agaatgccac ccttgagctc aaggccgcca
     5701 aagatttatt gtcacggatt cagaaaaggt ttcagaagcc tcaggaaaag ttgaaggcat
     5761 tgaaggaggc cagcagcctc ctctcaaacc acatcgctga cctgcaggct gcagaggagc
     5821 tcctcagaga agctgggagc aagacccagg aaagcagcct cctgctgctc cttgtcaagg
     5881 ccaacctgaa agacttcagg gagaaaaagc tgcatgttca agaggaacaa aatctgacct
     5941 caaagctcat tgcccaagga agagaatggg tagatgctgc caggactcat gcagctgctg
     6001 cccaagacac cctaacacag ctggagcatc accgagacga actcctattg tgggccagta
     6061 aaatcaggag ccacgtagat gacctcgtca tgcagatgtc caaacgaaga gcccgagacc
     6121 ttgtccacag ggcggagcag cacgcctctg agctgcagag tgcggcagaa gcattggaca
     6181 gagaccttga aaatgttaga aacgtgtctt tgaacgccac cagcgcagtg catgtccaca
     6241 ccaacatcca aacactgacg gaggaagcag agagtctggc tgcagatgct cacaagacgg
     6301 cgaataagac aagcttgatc tcagaatccc tggctcctcg ggggaaagca gtccttcagc
     6361 gttcttccag atttgtaaaa gaaagcgtca gtaccaggaa gaagcagcaa ggcattacgt
     6421 tgaagctgga tgagttgaaa aacttgacga gtcagtttca ggagcgtgtg gacaacatta
     6481 caagacaggc caacgactcc ctcacagtac tcagagaaag cccgggaggt atgagagaga
     6541 agagtaggaa agtcaaagag ctggcagtgg cagccaatga gactgcggcg aggacactgg
     6601 aggacatgct gggtttgagc ctaagggtct tcaacacatc cgaggacttg tccagggtga
     6661 atgccacagt ccaggagaca aaggaccttc tgcataactc cacaatgacc actatcttgg
     6721 ctggaaggaa aatgagagac atggaaatgc aggccaacct tctgttcgat cgattgaagc
     6781 ctttgaaaat gctggaagaa aacctgagca gaaacctgtc ggagatcaag ctgctcatca
     6841 gccgggcccg gaagcaagca gcttcgatca aagtagccgt gtctgcggac agagactgca
     6901 ttcgggccta ccagcctcag atttcttcta ccaattacaa caccttgtta ctgaacgtta
     6961 agacccagga gccggacaac cttctcttct accttggcag cagcagcagc tccgactttc
     7021 tcgcagtgga gatgcggcgt gggaaggcag cctttctctg ggacctgggc tctggctcta
     7081 ccaggttgga attcccagat gtctccatca acaacgacaa atggcatagc atctacataa
     7141 ccaggtttgg aaacatgggg tccctgagtg taaaggaagc aagtgcagct gaggacccac
     7201 cggtcaggac aagcaaatct cctggactgg cgaatgttct ggacataaac aattcgacgc
     7261 taatgttcgt tggagggctt ggaggtcaaa tcaagaaatc cccggctgtg aaggttactc
     7321 attttaaggg ctgcatggga gaggccttct tgaatggcaa atccattggc ctgtggaatt
     7381 acatcgaaag agaggggaag tgcaatggct gctttggaag ctcccagaac gaagacgctt
     7441 ccttccattt tgatggaagc gggtacgcag tggtggagaa ggctctccgt cccaccgtga
     7501 cacagataat aattctcttc agcaccttct ccccgaatgg gcttcttttc tacctggctt
     7561 caaacggcac taaggacttc ctgtccatcg aactgttgcg tggcagggtt aaagtgatgg
     7621 tggacctggg ctcaggaccc ctcactctta tgacggacag gcggtataac aacggaacct
     7681 ggtataaaat cgccttccag cggaaccgga agcaaggact gctagctgtc ttcgatgcat
     7741 atgacaccag tgacaaggag acaaagcaag gagaaactcc aggagccgct tccgacctca
     7801 atcggctgga gaaagacctg atttacgtgg gcggattacc tcactctaag gctgtgagga
     7861 aaggggtcag cagcagaagc tatgtgggct gtatcaagaa cctggagata tccaggtcca
     7921 cctttgattt gctgagaaat tcctatggag tgagaaaagg ctgcacgctg gagcctatcc
     7981 agagtgtgag cttcctgaaa ggcggctaca tggagatgcc acccaagtct ctgtcgccag
     8041 agtcatccct gctggccaca ttcgccacca agaacagcag tggagtcatc ctggctgccc
     8101 tgggcaagga tgcggagaag gctggggcgt ctcaggcaca tgtgcccttc ttttccatcc
     8161 tgctgattga aggccgcatc gaagtgcaca tcaactctgg ggatgggacc agtctaagga
     8221 aggccctcct gcacgctccc accggctctt acagtgatgg acaagaacat tccatctccg
     8281 tggttaggaa tcggagagtt atcaccgtac agctggacga gaacagccct gtagaaatga
     8341 agttgggtcc gttaacagaa ggaaggacga tcaacatatc caacctgtac atagggggac
     8401 ttcctgaggg caagggaacc ccgatgatca ggatgcggac atcgttccac gggtgtatta
     8461 aaaacgtggt catcgatgct caacttttgg actttacccg tgcggctggt tctgaacaag
     8521 tagagctgga cacatgcttg ctggcagaag aacccacaca gggcctgcac agagaacatg
     8581 gggaactccc tccagaaccc ccaacgctac cagagcctga actctgtgca gtagacacgg
     8641 ctcctgggta tgtggcagga gctcaccagt ttggcctctc gcagaacagc cacttggtgc
     8701 tcccttttaa tcagtctgac gtccggaaga ggctccaggt gcagctgaac atccggacat
     8761 ttgcctccag tgggcttatt tactacgtgg ctcatcagaa ccaaatggac tacgccgtgc
     8821 tccagctcca cgagggccgc ctgaacttca tgtttgacct tggcaagggc cgaaccaagg
     8881 tctctcaccc tgccctgctc agcgacggca agtggcacac cgtcaagacg gagtacatta
     8941 aaagaaaggc cttcatgact gttgacggcc aagagtcccc cagtgtcact gtggtgggca
     9001 atgcaaccac gctggatgtg gaaaggaagc tgtaccttgg aggccttcct gctcactaca
     9061 gggccaggag catcgggact atcacccaca gcatccctgc ttgtatcggg gacgtgacgg
     9121 ttaatagcca gcagctggat aaagacaggc cggcctccgc ctttgcagtg gacaggtgct
     9181 atgcggtggc ccaggaagga actttctttg aaggaagtgg atatgcagct cttgtgaagg
     9241 aaggctacaa agttcgactg gatttaaata tcacactgga gttccgaact tcctctaaga
     9301 atggcgtcct cctgggaatc agcagtgcca aagtggatgc cattggtcta gagattgtag
     9361 acggcaaggt ctcatttcac gtcaacaacg gtgctggaag gataacagcc acctacaaac
     9421 ccagagccac cagaactctc tgtgatggga aatggcacac gctccatgcc cacaaaagca
     9481 ggcaccgaat cgtcctgact gtggatgggg acgccgttag ggctgaaagc cctcacaccc
     9541 actccacctc ggcagacact aacgacccca tttatgtggg tggctacccc gcccacgtca
     9601 aacagaactg cctgagcagc cgggcctcgt tccggggctg tgtgaggaat ctcgagctga
     9661 gcagaggctc acaggtgcaa tccttggact tgagcagagc ctttgacctc cacggagttt
     9721 tccctcactc ctgcccgggg cctgagccct gatctgccgc cagactcttc ccttggaatc
     9781 atcgccagtg ccttgaggag aacagtctgt gaagtcaagc gtctttcatt cccattccag
     9841 ctcaggttgc atttccagag gaaaatgctg tatttatgtt gaagtaaagc cagatggata
     9901 acagatacct ctattaaatg gtctaaagtg tcagtggtaa aaaaaaaaaa aaaaa
//
