LOCUS       NM_001024247            1227 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus lactamase, beta 2 (Lactb2), mRNA.
ACCESSION   NM_001024247 XM_216316
VERSION     NM_001024247.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1227)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1227)
  AUTHORS   Levy,S., Allerston,C.K., Liveanu,V., Habib,M.R., Gileadi,O. and
            Schuster,G.
  TITLE     Identification of LACTB2, a metallo-beta-lactamase protein, as a
            human mitochondrial endoribonuclease
  JOURNAL   Nucleic Acids Res 44 (4), 1813-1832 (2016)
   PUBMED   26826708
REFERENCE   3  (bases 1 to 1227)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC093378.1.
            
            On May 27, 2005 this sequence version replaced XM_216316.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC093378.1, SRR8487226.134238.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1227
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q11"
     gene            1..1227
                     /gene="Lactb2"
                     /note="lactamase, beta 2"
                     /db_xref="GeneID:297768"
                     /db_xref="RGD:1307876"
     exon            1..171
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..916
                     /gene="Lactb2"
                     /note="beta-lactamase-like protein 2"
                     /codon_start=1
                     /product="endoribonuclease LACTB2"
                     /protein_id="NP_001019418.1"
                     /db_xref="GeneID:297768"
                     /db_xref="RGD:1307876"
                     /translation="MAAALQRIEQLSSRVVRVLGCNPGPMTLQGTNTYLVGTGSRRIL
                     IDTGEPSVPEYISCLKQALAEFDTAIQEILVTHWHRDHSGGIVDICKNISNDATYCIK
                     KLRRNPQKEEIIGSGEQQYVYIEDGDLIKTEGATLRVLYTPGHTDDHMALLLEEENAI
                     FSGDCILGEGTTIFEDLSDYMNSLKDLLKVKANIIYPGHGPVIHNAEAKILEYISHRN
                     NREEQIITVFRDNLEESFSVSELRKMIYKNVPENLHKMAEHNLLLHLRKLEKDGKIFS
                     IASPAKKWRASL"
     exon            172..335
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
     exon            336..462
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
     exon            463..641
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
     exon            642..790
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
     exon            791..872
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1203
                     /gene="Lactb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctggccgag tgacttaaaa tttaggcgcc ggcggtcacc gaggtagaaa tggctgccgc
       61 tctgcagcgc atcgagcagc tgtccagtcg ggtggtacgc gtgctgggct gtaacccggg
      121 tcccatgacc ctgcaaggca ccaacacgta cctggtggga accggcagca ggagaatcct
      181 cattgacacg ggagagccat cagttccaga atatatcagc tgtttaaagc aggccttggc
      241 tgagtttgac accgcaatcc aggaaattct ggtgactcac tggcaccgag atcattctgg
      301 aggcatcgta gacatttgta aaaacatcag taatgatgcc acttattgca ttaaaaaact
      361 tcgacggaat cctcagaaag aagaaattat aggaagtgga gaacagcaat atgtttatat
      421 agaagatgga gacttgatta agactgaggg agccacgctc agagtcttat acactcctgg
      481 ccacactgat gatcacatgg ctttactcct ggaagaggaa aatgccatct tttctgggga
      541 ctgcatccta ggagaaggga caacgatatt tgaagacctc tctgattaca tgaactccct
      601 aaaagactta ctaaaagtca aagccaacat tatatatcca ggacatggcc cagtgatcca
      661 taatgccgaa gctaaaattc tggaatatat ttctcaccga aataaccgag aagaacaaat
      721 tatcaccgta ttccgtgata accttgagga atcattctca gtgagcgaac ttaggaaaat
      781 gatttacaag aacgttccag agaatttaca taaaatggcg gagcataatc tcttgcttca
      841 cttgaggaaa ctagagaaag atgggaaaat attttccatc gcaagtcctg ccaagaaatg
      901 gagagcctcc ctttagtttc agatcaataa agttctcatt ttgcttttag aagatggtat
      961 tttcttttag ctataaatta catatttata gaaaatatca aatgtacaac tttgaaaata
     1021 acttttaaca cctttgtgaa atatgtaaat tacgttttat gtatgtagga caggttactg
     1081 atctaacctg ggtcttggaa ggttttacca gaaattcaga atctagcact ttatcacttt
     1141 cctagggatt aagtacagtg gttacttaag ggtaataaat gttgaacaat tcaaaccagt
     1201 taaaaaaaaa aaaaaaaaaa aaaaaaa
//
