LOCUS       NM_001401691            3278 bp    mRNA    linear   ROD 07-OCT-2023
DEFINITION  Rattus norvegicus similar to human chromosome 19 open reading frame
            12 (C1h19orf12), transcript variant 1, mRNA.
ACCESSION   NM_001401691 XM_006228915
VERSION     NM_001401691.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3278)
  AUTHORS   Venco P, Bonora M, Giorgi C, Papaleo E, Iuso A, Prokisch H, Pinton
            P and Tiranti V.
  TITLE     Mutations of C19orf12, coding for a transmembrane glycine zipper
            containing mitochondrial protein, cause mis-localization of the
            protein, inability to respond to oxidative stress and increased
            mitochondrial Ca(2)
  JOURNAL   Front Genet 6, 185 (2015)
   PUBMED   26136767
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3278)
  AUTHORS   Landoure G, Zhu PP, Lourenco CM, Johnson JO, Toro C, Bricceno KV,
            Rinaldi C, Meilleur KG, Sangare M, Diallo O, Pierson TM, Ishiura H,
            Tsuji S, Hein N, Fink JK, Stoll M, Nicholson G, Gonzalez MA,
            Speziani F, Durr A, Stevanin G, Biesecker LG, Accardi J, Landis DM,
            Gahl WA, Traynor BJ, Marques W Jr, Zuchner S, Blackstone C,
            Fischbeck KH and Burnett BG.
  CONSRTM   NIH Intramural Sequencing Center
  TITLE     Hereditary spastic paraplegia type 43 (SPG43) is caused by mutation
            in C19orf12
  JOURNAL   Hum Mutat 34 (10), 1357-1360 (2013)
   PUBMED   23857908
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000033.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001401691.2.
            
            On Feb 18, 2022 this sequence version replaced XM_006228915.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR8487230.35427.1, FM044117.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-237               JACYVU010000033.1  14750548-14750784
            238-407             JACYVU010000033.1  14755389-14755558
            408-3278            JACYVU010000033.1  14761289-14764159
FEATURES             Location/Qualifiers
     source          1..3278
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..3278
                     /gene="C1h19orf12"
                     /note="similar to human chromosome 19 open reading frame
                     12"
                     /db_xref="GeneID:690000"
                     /db_xref="RGD:1585208"
     exon            1..237
                     /gene="C1h19orf12"
                     /inference="alignment:Splign:2.1.0"
     exon            238..407
                     /gene="C1h19orf12"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..673
                     /gene="C1h19orf12"
                     /codon_start=1
                     /product="protein C19orf12 homolog"
                     /protein_id="NP_001388620.1"
                     /db_xref="GeneID:690000"
                     /db_xref="RGD:1585208"
                     /translation="MPIMVDDIMKLLCSICQEKKMKAAVKHSGRGAVVVGAMAFVGGL
                     VGGPPGLAVGGTVGGLLGAWMTSGQFKPVPQILMELPPAEQQKLVNEATAIIRNLDWT
                     DAVQLTALVMSNQAMQQKLLAMLTTYVTKELQAEIRYDD"
     exon            408..3278
                     /gene="C1h19orf12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggagcca gggaggcggt ggcctgtgaa cgcctctctg gagcccgcag agcggagttg
       61 gcctcagtac ccgagcgtcc cagactccag cacggtaaag gtgcgcgcgg ggaagccggg
      121 gtctgaggag ccggtcgggg accctgctgg aggtgtctgg cacactgctg gagctgttca
      181 tctcaatgca aaggagccga aacactgccg ggcctaagct gcagcgccga ggttggagtc
      241 tgccgagatg cccatcatgg tagatgacat catgaagctt ctatgctcca tttgccagga
      301 gaagaaaatg aaggcggccg tcaagcactc tggaaggggt gccgtggtcg tgggggcaat
      361 ggccttcgtc ggcggtttgg ttggtggccc accaggatta gctgtcgggg ggactgttgg
      421 gggcctgtta ggtgcctgga tgacaagtgg acagtttaag cccgttcctc agatcttaat
      481 ggagctgccc cccgctgaac agcagaaact tgttaacgaa gccactgcca tcatcaggaa
      541 cttggactgg acagacgctg tgcagctgac cgctctagtc atgagcaacc aggccatgca
      601 gcagaagctc ttggccatgc taaccaccta tgtcaccaag gagctgcagg ctgagatccg
      661 ctacgatgac taagtcgccc cccccccccg tggaatgggg gtttcatttt agattattct
      721 gtggctctca gaaggtggcc agggaatggg ggaagcctac caggtacttc tgagaaactt
      781 gtatattacc agcactggtt gtaagctggc tagtacatcc tgttggactg tcctgttgga
      841 gaggccttgg gcgtgcatct tgggctgtgt gtgctatggg gaggtacagg caggcccgct
      901 gtaggtcatg tgtctaaaag aagttctcat gccgttggcc ggccaactct accaaatgtt
      961 cctctttctg taaagagtgt acctccaggt acctgtcaca ggattggatc cccttaagct
     1021 ctggggtctc ggggttcaga gccagctctt gtcaggattc tgtttacctg tgagtgtttc
     1081 ccttccttgg ccagggactt ctcagtggtc tcatgatgaa cggtccctcc tgtgagtgaa
     1141 gccacagatg acaggcggtc tctgtgctct gccactggca atgtccccca ggctctcttg
     1201 agtaacttta gttaagtttc taggatcatt tgcctcccta tggaaaatca tggcacttct
     1261 ttatctttta tttttaatgt caatttctgg accctttttg ttctctacac tttcgaggcc
     1321 taagttaatt tagctccatt ttctttttct tcttactatg tttcctgggc cagccttgaa
     1381 gtcctggact caagtgatcc tgctacggag ctggggacag aaggcttgtg tcaccatacc
     1441 tagctttacc tcaaagactg ttctactcca ctttttctga gtccttccat ggtctcctct
     1501 cagctgtctg caatctatct ataattcatt tgtgtgaaaa gacaacatta acagtgaatt
     1561 caaagaccct aactgagcca ggcgctgtga tactcacagc ctcagataac tgaaaggcca
     1621 aagtggagca tccttgggtc caggaattca aggccaaccc ggacatagcg gaagccggga
     1681 gatacacgag acgttacaca ccttcttggt tggcctttat ttgcagtcac agagtcaaga
     1741 agcagcaagt gttctgatga gatggaaaga gatgagagac aggggagacc aagggaaggc
     1801 aggaacaaca agaacactag gttaacctcc catgacactg gctctttaca gatcgggcta
     1861 gcctctcctc atttctctaa gtgacagtgg ctcaaatcca acaagtagct tgcttgtttg
     1921 ttttccttgt ggtgttgtgg acggaaccca gggccttgta taagctaagt gccaccacgg
     1981 aaccctgctc ccagtccttt cttggtagat cctaggctag ttctcggagt aatgtgggag
     2041 tctgctggtt accccctgag cccggtcccg gtccttcagt tctggtttag tcagttggtc
     2101 ctagtgctgt cgctcaacca ataacatcgt atgcatttga ctcagtattg gatacttcct
     2161 ttttatccct cactggggat gctcactcat ggagggcagg agctgtgtgc cccgatcacc
     2221 tatctccagc ttgctcctgc ctggtaccgt ggcttttatt gtgctagaca ctcaataaat
     2281 atatattttt aaagctctgt attttatatc ttcctggttg gttatttatt tatttatttt
     2341 tcatgttttg tctatatttc tgtaagtatg ctgtatgtgt ctggttccca cagaggctgt
     2401 taagtgggca ctggacctcc aggaaccgat gttactgacg attgtgagcc accacgtggg
     2461 tgctgggaac tgaacccagg ccctctgcaa gggcatcaat ggctaaacaa tttcacctct
     2521 tctaggtttg agtctttaaa ctcgggcttc tctgtgtgat tctggttggc ctcaaaccca
     2581 tggtcttcct gcctcagccc cttgaactct gagattactg gcaggcatga ccaagacaag
     2641 acagataagt ggtttttttt tttttttgtt gttgttagaa gtctttaagt tcttattgtt
     2701 tctggttttt tgtttgttca gttctttttg ttttatttgt tttttgtttt gctttgtttt
     2761 gagacaggat ctcatgtagc ccaggctggc ttccaactcc aagtagccaa agatgacctt
     2821 gaactcttga ttatccaggc tctatcactg ctaagtgttg ggattccaga gacacacctt
     2881 tatgtctggc ttcagtaaat atttttggaa gtcatggttt tgaaaccact tcctatggaa
     2941 ttcctccagt aacgaaacat gtgacaaaag agacctagaa tcaaatttca agcttttcga
     3001 agcccctgag ctactaatca cagaagctgg ggtttggcct ggcgtcccta gaacccagag
     3061 ccctcgccgg aacaccgtgt ggtagtcccc ccggttttca caaacgtgta tgagacatgt
     3121 tttcacctga aatagtttta gtccaatgta tgctgtctcc aaagtggggc atcccaactt
     3181 ccggtatttc taccccaagg tctccctgaa tgctgtacct tttcaaaact acaacctgac
     3241 tatcgtccaa ttactaataa attacttttc cttgaaaa
//
