LOCUS       NM_001101007            2261 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus keratin 6c (Krt6c), mRNA.
ACCESSION   NM_001101007 XM_001065121 XM_001065178
VERSION     NM_001101007.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Paine,M.L., Gibbins,J.R., Chew,K.E., Demetriou,A. and Kefford,R.F.
  TITLE     Loss of keratin expression in anaplastic carcinoma cells due to
            posttranscriptional down-regulation acting in trans
  JOURNAL   Cancer Res 52 (23), 6603-6611 (1992)
   PUBMED   1384967
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099121.1.
            
            On or before Aug 13, 2007 this sequence version replaced
            XM_001065178.1, XM_001065121.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099121.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132281,
                                           SAMEA5756307 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2261
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /note="keratin 6c"
                     /db_xref="GeneID:683313"
                     /db_xref="RGD:1588056"
     exon            1..540
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1692
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /note="keratin K6; K6a keratin; cytokeratin-6A; type-II
                     keratin Kb6; keratin, type II cytoskeletal 5; keratin,
                     type II cytoskeletal 5-like"
                     /codon_start=1
                     /product="keratin, type II cytoskeletal 6A"
                     /protein_id="NP_001094477.1"
                     /db_xref="GeneID:683313"
                     /db_xref="RGD:1588056"
                     /translation="MSTKTVIRSQTSHRGFSAGSARLPGLNRSGFSSVSVCRSRGSGG
                     SRAVCGGAGFGSRSLCGVGSSQRISIGGGSCGIGGGYGGRFGGSFGYGGGAGGSLGFG
                     AGAGFGGGYGGAGFPVCPPGGIQEVTINQSLLTPMNLQIDPTIQRVRTEEREQIKTLN
                     NKFASFIDKVRFLEQQNKVLDTKWALLQEQGTKTVRQGLETLFEQYINDLRKELDNIL
                     GQRGRLDSELRNMQGTVEDYKSKYEDEINRRTAAENEFVTLKKDVDAAYMNKVELQAK
                     ADSLTDEINFLRALYEAELSQMQTHISDTSVVLSMDNNRSLDLDSIIAEVKAQYEEIA
                     KRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEISEINRMIQRLRSEIDHVKKQIA
                     NLQAAIAEAEQRGEMALKDARGKLEGLEDALQKAKQDMARLLKEYQDLMNVKLALDVE
                     IATYRTLLEGEECRLNGEGVGPVNISVVQSTVSSSYGSAGGASSSIGLGGSSSFSYGG
                     SHSIGGGFSAGSGRGISSGLSSSGGSSSTIKYTTTSSTRKSYRP"
     exon            541..755
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            756..816
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            817..912
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1077
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1203
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1424
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1459
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..2222
                     /gene="Krt6c"
                     /gene_synonym="CK-6A; Krt6a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttctcctct actgcctctc atctcacaga accatgtcta ccaaaaccgt catccggagt
       61 caaaccagcc accgtggctt cagtgcgggc tcagccagac tgcctgggct caaccgctct
      121 ggcttcagca gtgtgtctgt gtgccgctcc aggggcagcg gtggctcccg tgcagtgtgt
      181 ggaggagctg gctttggcag caggagtctc tgtggtgtgg gcagctccca gaggatctcc
      241 atcggagggg gcagctgtgg cattggagga ggctatggcg gccggttcgg aggcagcttc
      301 ggctatggag gaggagctgg aggtagcctt ggctttggtg ctggagctgg ctttggtggt
      361 ggctatgggg gagccggctt cccagtttgc ccacctggag gcatccaaga ggtcaccatc
      421 aaccagagcc tcctcacacc catgaacctg caaatcgacc ccaccatcca gcgggtcagg
      481 actgaggaga gggagcagat caagaccctc aacaacaagt ttgcctcctt catcgacaag
      541 gtgcggttcc tggagcagca gaacaaggtc ctggacacca agtgggccct gctgcaggag
      601 cagggcacca agaccgtgag gcagggtctg gagactttgt ttgagcaata catcaacgac
      661 ctccgcaaag agctagacaa catccttgga cagaggggtc gcctggactc agaactgagg
      721 aacatgcagg gcacagtgga ggactacaag agcaagtatg aggatgaaat taacaggcgc
      781 acagcagcag agaatgaatt cgtgaccctg aagaaggatg tagatgctgc ctacatgaac
      841 aaggttgaac tgcaagccaa ggcagacagt ctaacagatg agatcaactt cctgagagct
      901 ctctatgaag cagaactgtc tcagatgcaa acccacatct cagacacatc tgtggtcctc
      961 tccatggaca acaaccgcag cctggatctg gacagcatca ttgctgaggt caaggcccag
     1021 tatgaggaaa ttgcaaagag aagtcgggct gaggctgagt cctggtacca gacaaaatat
     1081 gaggagctgc agatcacagc tggcagacac ggggacgacc tgcgcaacac caagcaggag
     1141 atctctgaga tcaatcgcat gatccagagg ctgaggtctg agatcgacca cgtgaagaag
     1201 cagattgcca acctgcaagc tgccattgcc gaggctgagc agcgtgggga gatggccctg
     1261 aaggatgcca ggggcaagct ggaagggctg gaggacgccc tgcagaaggc caagcaggac
     1321 atggccaggc tgctgaagga gtaccaggac ctcatgaatg tcaagctggc cctcgatgtg
     1381 gagatcgcca cctacaggac gttgctggaa ggagaggagt gcaggttgaa tggtgagggc
     1441 gttggaccag tcaacatctc cgtggtgcag tccaccgtgt ccagcagcta tggcagtgca
     1501 ggtggtgcca gcagcagcat aggcctggga ggaagcagca gcttctccta tggtggtagc
     1561 cacagcattg gaggtggctt cagtgctggc agtggcagag gcatcagcag tggactcagc
     1621 tcctctggtg gcagctcttc caccatcaag tacaccacca cctcctccac caggaagagc
     1681 tacaggccat gaattctgtc tcttagagct ttaccctgat accagatatc atggctgcag
     1741 agccctttgc tcagagccct gtgctcaggg ccttctcctt gctagacacc aacctctgct
     1801 gtcttcttgt gctgaggaaa ttgtgtcctt gtgcccatct ctctgtcccc actgctcatc
     1861 ccttgatagt catgctctga gctcacatca tgattcacac acacttggtg cttcatgttg
     1921 tatttggttt ccaggctcct gcctctctac ctctaacact gaggctgcct gtgaaagggt
     1981 gtctctgtca ttttaattct tggaatcatt gtctgggtcc tactcaagaa atgagcacct
     2041 cttttttagt tttcaatggc ctgtgaaacc ccatttttca acatcataaa cctttttgta
     2101 agtaactgtg actgcccagt cactggtcct gtgatgtaga atctgtgctc atgtgatgtc
     2161 tttgcttttc ttgatgctct ttgtttcctt atatttgcta aataaagcag atttataaac
     2221 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
