LOCUS       NM_001163214            2957 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus similar to human chromosome 10 open reading frame
            90 (C1h10orf90), transcript variant 1, mRNA.
ACCESSION   NM_001163214
VERSION     NM_001163214.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2957)
  AUTHORS   Yan,S., Qiu,L., Ma,K., Zhang,X., Zhao,Y., Zhang,J., Li,X., Hao,X.
            and Li,Z.
  TITLE     FATS is an E2-independent ubiquitin ligase that stabilizes p53 and
            promotes its activation in response to DNA damage
  JOURNAL   Oncogene 33 (47), 5424-5433 (2014)
   PUBMED   24240685
REFERENCE   2  (bases 1 to 2957)
  AUTHORS   Knorz,V.J., Spalluto,C., Lessard,M., Purvis,T.L., Adigun,F.F.,
            Collin,G.B., Hanley,N.A., Wilson,D.I. and Hearn,T.
  TITLE     Centriolar association of ALMS1 and likely centrosomal functions of
            the ALMS motif-containing proteins C10orf90 and KIAA1731
  JOURNAL   Mol Biol Cell 21 (21), 3617-3629 (2010)
   PUBMED   20844083
REFERENCE   3  (bases 1 to 2957)
  AUTHORS   Zhang,X., Zhang,Q., Zhang,J., Qiu,L., Yan,S.S., Feng,J., Sun,Y.,
            Huang,X., Lu,K.H. and Li,Z.
  TITLE     FATS is a transcriptional target of p53 and associated with
            antitumor activity
  JOURNAL   Mol Cancer 9, 244 (2010)
   PUBMED   20843368
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2957)
  AUTHORS   Li,Z., Zhang,Q., Mao,J.H., Weise,A., Mrasek,K., Fan,X., Zhang,X.,
            Liehr,T., Lu,K.H., Balmain,A. and Cai,W.W.
  TITLE     An HDAC1-binding domain within FATS bridges p21 turnover to
            radiation-induced tumorigenesis
  JOURNAL   Oncogene 29 (18), 2659-2671 (2010)
   PUBMED   20154723
REFERENCE   5  (bases 1 to 2957)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Apr 7, 2023 this sequence version replaced NM_001163214.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167765.1, SRR26360181.415760.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-138               JAXUCZ010000001.1  198580890-198581027 c
            139-230             JAXUCZ010000001.1  198574739-198574830 c
            231-1347            JAXUCZ010000001.1  198565463-198566579 c
            1348-1632           JAXUCZ010000001.1  198524603-198524887 c
            1633-1811           JAXUCZ010000001.1  198521595-198521773 c
            1812-1989           JAXUCZ010000001.1  198518797-198518974 c
            1990-2053           JAXUCZ010000001.1  198494068-198494131 c
            2054-2153           JAXUCZ010000001.1  198490576-198490675 c
            2154-2957           JAXUCZ010000001.1  198489686-198490489 c
FEATURES             Location/Qualifiers
     source          1..2957
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..2957
                     /gene="C1h10orf90"
                     /note="similar to human chromosome 10 open reading frame
                     90"
                     /db_xref="GeneID:100302465"
                     /db_xref="RGD:2311471"
     exon            1..138
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..2192
                     /gene="C1h10orf90"
                     /note="isoform 1 is encoded by transcript variant 1;
                     centrosomal protein C10orf90 homolog; (E2-independent) E3
                     ubiquitin-conjugating enzyme FATS"
                     /codon_start=1
                     /product="(E2-independent) E3 ubiquitin-conjugating enzyme
                     FATS isoform 1"
                     /protein_id="NP_001156686.2"
                     /db_xref="GeneID:100302465"
                     /db_xref="RGD:2311471"
                     /translation="MALKHQWDMIKLSGEGSLHMRYSTNDQIALKNLQSGVTERKLDF
                     SKETLASQNTRMISPVVISRLIDEKKSMENGAVLSQAIAQPQLCPPKPASARPGGVSK
                     HRPFALSPDGLGILAPSDEQGLEIEPLSTGDNLGKGPRSGFSSITITARRVGPPASNL
                     VWDTFRDPLCSKCGTKDAGFQDPPVLASGAHLCQHNRPYSYTEFPSNGSVEGLKVTQA
                     HSRLCARQDYWVTHADDNEDSFSSDNSPSRKVPLVFSSCVHLRVSQQCPSAIYYLDKS
                     LSVPLEQPQIASPKMHRSVLSLSLRCSSHQLTADGVDSPANGEPISRALSQELSEGKQ
                     DLLGSQWGQPQEGHWKESPALVPVHLGSGTCPQTGSPPLENVKFADVGRNQVPVHKEK
                     EDHATCTNSSHSNQLSIHIPGWSYRAETKVLSRSKKQQHQAQRTLSAFPVGQKPIKHF
                     PPDGDSLPSNDGQPNILSESHKRQHSYFMTPKVPLSGFFCPLQTVCASLQEDDAIQIE
                     TQFPKDYTCCDLVVKLKDCEKHEDPTVTPEPSPATPSPATRAGPQSSGPLEDSFEPLM
                     ASSMTLQEALEVHRPQFISRSQERLQKLKHMVQQRKTQQKESLGQKQSLLPVRANKKQ
                     FTIPHPLSDNLFKPKERCISEKEMHMRSKRIYNNLPEVRKKKEEQKKRVILQSNRLRA
                     EVFKKQLLDQLLQRNAV"
     exon            139..230
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            231..1347
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1632
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1811
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            1812..1989
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            1990..2053
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2153
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
     exon            2154..2957
                     /gene="C1h10orf90"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttctgagag tagctacaga ggcaaactgg ccatgttcct tgatttagca aggcacatct
       61 ttgttcgtag atggtctttg aaatgaagta agatggcttt gaaacatcag tgggacatga
      121 ttaaactgtc tggggaagga tctctgcaca tgcgctatag tacaaatgat caaatcgccc
      181 ttaaaaacct ccagtctggt gttacagaga ggaagctgga cttctccaag gagacactgg
      241 catcacagaa cacaagaatg atatcacctg tcgtcatttc ccggctgatt gatgaaaaga
      301 aatcgatgga aaatggagct gtgttgtcac aagcaatcgc ccagcctcag ctgtgtcctc
      361 caaagccagc ttcagctagg cccggtggag tgagcaagca caggccattt gctttatctc
      421 ctgatggatt aggaattttg gctccatcag atgagcaagg actggagata gaaccactgt
      481 ctacagggga caatctaggc aaaggtcccc gcagtggctt ctcttctatc accattactg
      541 cccgacgtgt gggtcctcca gccagcaact tggtatggga cacttttagg gacccactgt
      601 gttccaagtg cgggaccaag gatgctgggt tccaagaccc cccagttctg gctagtggtg
      661 cccatctatg tcaacacaat agaccctaca gctatacaga gttccccagc aatggctctg
      721 tggaggggct gaaggttact caggctcact caaggctgtg tgcaaggcag gactactggg
      781 tcacccatgc ggatgataat gaggacagtt tttcttccga caattcacca tcaagaaaag
      841 tcccactggt atttagttct tgtgtccacc tccgggtgtc tcaacagtgt cccagtgcca
      901 tttactattt ggacaagtct ctttctgtcc cccttgagca acctcaaatt gctagcccca
      961 aaatgcacag gtctgtcctg tctctcagcc tccgctgtag ttcccaccag ttaacagcag
     1021 atggagtaga cagcccagct aatggagagc caatcagcag agctctatca caggaactct
     1081 ctgagggaaa acaggacctc ctaggctcac aatggggcca gccacaagaa ggtcactgga
     1141 aggagagccc agcattggtg ccagtacatt tggggagtgg cacatgccct cagactggct
     1201 cccctccact ggaaaatgtc aaatttgcag atgtgggaag aaaccaggtc ccagtacaca
     1261 aggagaaaga ggatcatgca acatgtacca atagcagcca ttctaaccaa ctctccatcc
     1321 atattcccgg atggagttac agggctgaaa caaaagtact ttctcggagc aagaagcagc
     1381 agcaccaagc acaaaggact ctttctgctt tcccagtggg acagaagccc attaaacact
     1441 tccctcctga tggggacagt ttaccaagca atgatggtca gcctaacatc ctttctgagt
     1501 cccacaagag gcaacactca tacttcatga cacccaaagt ccctctgtct gggttttttt
     1561 gccctttaca aactgtgtgt gcctctctgc aggaagatga tgctattcag atagaaacac
     1621 agttccccaa agattacacg tgctgtgact tggttgtaaa actaaaggat tgtgagaagc
     1681 atgaagaccc cactgtcaca cctgagccct caccagcaac cccctctcca gcaacccgag
     1741 cgggaccaca gagctctggc ccattggaag acagttttga gcctctgatg gcaagttcta
     1801 tgaccttgca ggaagcgctg gaagtccata gacctcagtt catttctcgc tcacaagaac
     1861 ggctgcaaaa gcttaagcac atggtacagc aaaggaaaac ccaacaaaag gagagcctgg
     1921 ggcagaagca aagcctactt cctgtccgcg ccaacaagaa gcagttcacc attccccatc
     1981 ctcttagtga taacttgttc aaacccaaag aaagatgcat ttcagagaag gagatgcata
     2041 tgagatctaa aagaatctat aataacttgc cggaagttag aaagaaaaaa gaagagcaga
     2101 agaaaagagt gatcttacag agtaacaggc tccgagcaga ggtcttcaaa aagcaattac
     2161 tggaccagct ccttcaaagg aatgcagttt gatcccaggc ggctctgcta gcccagcctg
     2221 aatctgggaa cacttctgat gatgacgctg gatgaaccat taaatttaat gctatcttca
     2281 cacatgaaag aaactttcac tttacttctg attttttttt ttttcccaca aaggaaacgt
     2341 cactttctga atgttccaaa caaaagcctt agaactgcaa gccgcagatc agcagtccat
     2401 tgctgggact tcgacccctt ggaaccgacc atttccaccc gagcaggaaa gctttatata
     2461 ttcaagtgtg cttggacgct tgttttttgt ttttgttttt cggggtgggg ggcaatgttt
     2521 tttcttttcc aaaaatgtaa gaagcaaaaa atctctcatg ttttaacttc caatcccaat
     2581 ggctgccagt tctgaaaaat ctaaagtcaa agttcatttt gaatacacgt cctggagtgc
     2641 cagaggctga tttgaagtgg actgatggat aggcagaaca cagaacaagc aggagagccc
     2701 tctgcctccc tcctgcccta cccgcagtgc ctgcctttgt tagccgcggt acctgtttca
     2761 gtgggagcca ggagactgag taaagatggc agggtcttca ccagccacac acaggaagtc
     2821 atcttgacca aatggcccag cggtacccac ttttatctat tctttcaagc tctcctccta
     2881 aatatgtatt tgtggagtta agaacaaatt agtttttgca acaaacgtgg aaataaaagc
     2941 agttgtttga aatgcaa
//
