LOCUS       NM_001108031            1837 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus trans-L-3-hydroxyproline dehydratase (L3hypdh),
            mRNA.
ACCESSION   NM_001108031 XM_001080576 XM_234277
VERSION     NM_001108031.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Visser WF, Verhoeven-Duif NM and de Koning TJ.
  TITLE     Identification of a human trans-3-hydroxy-L-proline dehydratase,
            the first characterized member of a novel family of proline
            racemase-like enzymes
  JOURNAL   J Biol Chem 287 (26), 21654-21662 (2012)
   PUBMED   22528483
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473947.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_234277.4, XM_001080576.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760476
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..1837
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /note="trans-L-3-hydroxyproline dehydratase"
                     /db_xref="GeneID:314214"
                     /db_xref="RGD:1305721"
     exon            1..815
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /inference="alignment:Splign:2.1.0"
     CDS             308..1372
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /EC_number="4.2.1.77"
                     /note="L-3-hydroxyproline dehydratase (trans-)"
                     /codon_start=1
                     /product="trans-3-hydroxy-L-proline dehydratase"
                     /protein_id="NP_001101501.1"
                     /db_xref="GeneID:314214"
                     /db_xref="RGD:1305721"
                     /translation="MEAALAVSRLPPHDPRTPALSVVDMHTGGEPLRIVHAGCPEVAG
                     PTLLAKRRYMRQHLDYVRRRLVFEPRGHRDMYGAILVPSELPDAHLGVLFLHNEGYSS
                     MCGHAVLALGRFALDFGLVPAPPEGTREAQVNIHCPCGLVTAFVECEGGRSCGPVRFH
                     SVPAFVLASDLTVDVPGHGKVVVDIAYGGAFYAFVSAEKLGLDVCSAKTRDLVNAASA
                     LTGAVKAQFKISHPESEDLGFLYGTILTDGKDVYSEEPTTNICVFADEQVDRSPTGSG
                     VTARIALQYHKGLLQLNQTRAFKSSATGSVFTGCAVREAKCGDFKAVIVEVAGQAHYT
                     GTANLTVEDDDPLRDGFLLK"
     exon            816..985
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1108
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1246
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1837
                     /gene="L3hypdh"
                     /gene_synonym="RGD1305721"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctctggag acacgccccc attccggagg tggggggaca ggggaggact agttttctaa
       61 gccctgccca ccctccttgt cttgtctcgg aggcccgccc gggctgtgtg tctagctcac
      121 acagctagct ggggcgcaca cacactaaga ttccaggcgc ttgtcactgg gtagtctcta
      181 ctcgccggct tgatcctgag attgccctcg gctctacgcc ttctcccgtg ggatttggcg
      241 ctcccccccg cccccaactc ggagagagca ccaccgtgca gtgcaacagt tggagtggac
      301 gcagacaatg gaagcggcgc ttgcagtgag ccggctgccc ccgcacgacc cgaggacgcc
      361 ggcactgtcg gtggtggaca tgcacacagg cggcgagcct ttgcgcatcg tgcacgccgg
      421 gtgtccggag gtggcagggc ccacgttgct ggccaagcgg cgctacatgc gtcaacacct
      481 cgactacgta cggcggcggc tcgtgttcga gccccgcggc caccgggaca tgtacggggc
      541 catcctagta cccagtgagc tgcccgacgc gcacctaggc gtcctgttcc tgcacaacga
      601 aggttacagc tccatgtgcg gccacgcggt gctggcgctg ggccgcttcg cgctcgactt
      661 cggactggtg cctgctcccc cagaaggcac ccgggaggcc caggtcaaca tccactgccc
      721 gtgcgggctg gtgaccgcct tcgtggagtg tgaaggtggc cgtagttgcg gccctgtgcg
      781 cttccacagc gtcccagcct ttgtcctggc ctcagacctc acagtggatg ttcctggcca
      841 tggaaaggtg gtggtggaca ttgcgtacgg tggggcgttt tatgcatttg ttagtgcaga
      901 aaaattagga ctcgatgtgt gttctgcaaa gacaagggat cttgtgaatg cagcaagcgc
      961 attgacagga gcggtgaaag cacagtttaa aataagccat cctgagagtg aagaccttgg
     1021 ctttctgtat ggaactatct taacggacgg aaaagatgtt tatagcgagg agcccaccac
     1081 caacatctgc gtgtttgcag atgagcaggt cgacagaagc cccaccgggt ccggagtgac
     1141 agccagaatt gctctgcagt atcataaggg gcttctgcag ctgaaccaga ccagagcctt
     1201 caaaagcagt gcaaccggct cggtgttcac gggctgcgct gtgagggaag caaagtgtgg
     1261 agatttcaaa gccgtcatag tggaagttgc aggacaagcc cattacacgg ggacagcaaa
     1321 cctgacagtg gaagacgatg acccactaag ggatggcttt cttctcaagt gacttttttt
     1381 tttcataagt tttaaaggtt tcccttagaa agtaataacc tttagctgat gccctctctg
     1441 ttatgtgcaa accagtatcc agttacacct ataggctaaa ttttgtactt tctaaaacag
     1501 tacactgttt taaatataag gtatcctact tcctatttgc caactttttg agcataaatg
     1561 tcactgatgg ggcaaacaga gtgctaagaa ttcagaaact ttttaatcat tagtatatgt
     1621 ggcaaaatta aaacccattt acttaatcta tgctatggaa atgataattc ttgtacattt
     1681 tctcgaatga cagtttcacc catagaacgc acaatagtaa atgttgtaag tttattttaa
     1741 tgttccagtg tgaataaaat aaagccagcc acaggcctcg tgctcatgga ggcgagttat
     1801 aatgttctca acacgtggca taaatagtct tggaagg
//
