LOCUS       NM_001413796            5450 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus kyphoscoliosis peptidase (Ky), mRNA.
ACCESSION   NM_001413796 XM_006243657
VERSION     NM_001413796.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5450)
  AUTHORS   Baker,J., Riley,G., Romero,M.R., Haynes,A.R., Hilton,H., Simon,M.,
            Hancock,J., Tateossian,H., Ripoll,V.M. and Blanco,G.
  TITLE     Identification of a Z-band associated protein complex involving KY,
            FLNC and IGFN1
  JOURNAL   Exp Cell Res 316 (11), 1856-1870 (2010)
   PUBMED   20206623
REFERENCE   2  (bases 1 to 5450)
  AUTHORS   Blanco,G., Coulton,G.R., Biggin,A., Grainge,C., Moss,J.,
            Barrett,M., Berquin,A., Marechal,G., Skynner,M., van Mier,P.,
            Nikitopoulou,A., Kraus,M., Ponting,C.P., Mason,R.M. and Brown,S.D.
  TITLE     The kyphoscoliosis (ky) mouse is deficient in hypertrophic
            responses and is caused by a mutation in a novel muscle-specific
            protein
  JOURNAL   Hum Mol Genet 10 (1), 9-16 (2001)
   PUBMED   11136708
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 9, 2022 this sequence version replaced XM_006243657.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.22750.1,
                                           SRR26643294.34219.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-201               JAXUCZ010000008.1  111965862-111966062
            202-264             JAXUCZ010000008.1  111968894-111968956
            265-327             JAXUCZ010000008.1  111972457-111972519
            328-402             JAXUCZ010000008.1  111981287-111981361
            403-465             JAXUCZ010000008.1  111983542-111983604
            466-548             JAXUCZ010000008.1  111984961-111985043
            549-657             JAXUCZ010000008.1  111986533-111986641
            658-775             JAXUCZ010000008.1  111987670-111987787
            776-964             JAXUCZ010000008.1  111996808-111996996
            965-1155            JAXUCZ010000008.1  111998310-111998500
            1156-5450           JAXUCZ010000008.1  112000912-112005206
FEATURES             Location/Qualifiers
     source          1..5450
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..5450
                     /gene="Ky"
                     /note="kyphoscoliosis peptidase"
                     /db_xref="GeneID:315962"
                     /db_xref="RGD:1305407"
     exon            1..201
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..2051
                     /gene="Ky"
                     /codon_start=1
                     /product="kyphoscoliosis peptidase"
                     /protein_id="NP_001400725.1"
                     /db_xref="GeneID:315962"
                     /db_xref="RGD:1305407"
                     /translation="MELKKDSNAVAIDMLLIVHSEKRRAAQATHLDPQADPGALLQNR
                     GGFQGVRNGIRKWQELEENGFQGNLPEKQCLQQPQVITSYDNQGTQLTVEIHPQDAMP
                     QLLKKFSLAKRLQGDKNGNMRPRQPGGKDAHAYPWDRSNLKSMPLDLRHFEKLDASAS
                     QVTLKSGLNELVSDLLQEAHSDLERVRAIWIWICHHIEYDVEAAQEKDRQAFKPTNIL
                     RTRKTNCDGYAGLFERMCRVAGVQCVTVPGYSKGFGYKTGQSFSGEFDHAWNAVYLEG
                     RWHLVDSTWGSGLVDTATSKFTFLYNEFYFLTHPALFIEDHFPDNKNWQLLKPPQSLR
                     QFENNMYHKSEFYNKGMLSAHPETPMIRTVNGKATVTIESRAPTLFMFMLNGKQEHGL
                     LSLRKNGMKLEVYPPTMGTHKLQIFAKGNSEIYSSVLEYTLKCNYVDFSVRLPTELHQ
                     PVGPSWFSEQMGIRKPSHPDPIIHTSDGRCSISFVVEEGISILASLHGDDSPITEETK
                     RRYIFQMNREKRTELKVQLPHAGKFALKIFVKKRQEQGNFVFVFNYLLCCANTKVNWP
                     MFPEIYGHWGQDNELLEPLSGVLPANRNIPFKLKLHGIAKALVKGQDTWPLTLNPEGY
                     WEGSCNTAGCQEVYVMVLENANHNFYSYILKYKVNDQ"
     exon            202..264
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            265..327
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            328..402
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            403..465
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            466..548
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            549..657
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            658..775
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            776..964
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1155
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..5450
                     /gene="Ky"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccatttgca gcctaggcag cctcgcgagc agccgctgtg cgccggccgg gagggaggcg
       61 gcaccatgga gctgaagaag gacagcaacg ctgtggccat cgacatgctg ctcattgtgc
      121 actccgagaa gcggcgcgcg gcgcaagcca cgcacttgga cccgcaggcg gacccgggcg
      181 cgctgctgca aaaccgagga ggattccaag gtgtcagaaa cggaatccgg aagtggcaag
      241 aattggagga aaacggcttt cagggaaact tgccagagaa gcagtgcctt cagcagcctc
      301 aggtcatcac ttcctatgac aaccaaggta ctcagctgac tgtggaaatc cacccccaag
      361 atgccatgcc ccagctgctt aagaagttct ctttggctaa acgtttacaa ggtgataaaa
      421 atggaaacat gagaccccgg cagcctggag ggaaagatgc ccatgcctac ccctgggaca
      481 gatccaattt gaaatccatg cccctggacc tccgacactt tgaaaaactg gatgcctctg
      541 cctcacaggt gaccctcaag agtggcctga atgagctggt gagtgacttg ctccaggaag
      601 cccacagcga tctggaaagg gtcagagcca tctggatctg gatctgccac catatagagt
      661 acgatgtgga ggctgcccag gagaaggacc gacaggcctt caaacccacg aacatcctga
      721 ggacccggaa gaccaactgt gatggttacg ctggcctctt tgaaaggatg tgcagggttg
      781 ctggtgtgca gtgtgtcacc gtgcctggct actccaaggg ctttggctac aagactggcc
      841 aaagcttctc tggagagttc gaccacgcct ggaatgctgt gtaccttgag ggtcgttggc
      901 acctggtgga cagcacctgg ggcagtggcc tggtggatac cgccacctcc aaattcacct
      961 tcctctacaa tgaattctac ttcctcaccc accctgccct attcattgag gaccacttcc
     1021 cagacaacaa aaactggcaa ctgctgaagc caccccagtc tctgaggcag tttgagaaca
     1081 acatgtacca caagagtgaa ttctacaata agggcatgtt gagtgcccac ccagagacgc
     1141 ccatgatcag aacagtgaac gggaaagcca ccgtcaccat agagagccgt gccccgacac
     1201 tgttcatgtt catgctcaac ggcaagcaag agcacgggct cctgagcctc aggaagaacg
     1261 ggatgaaact ggaggtgtac cctccaacca tgggcaccca caagctgcag atcttcgcca
     1321 aaggcaactc tgaaatctac agttcggtgc tggaatacac gctcaagtgc aactatgtag
     1381 acttctctgt ccggctgccc actgagcttc accagcccgt gggccccagc tggttctcgg
     1441 agcagatggg catcaggaag ccctcacacc ctgaccccat catccacacc agcgacggtc
     1501 gctgctccat cagctttgtg gtggaagagg gcatcagcat cctggcatcc cttcatggcg
     1561 atgacagtcc catcaccgag gagacaaaga ggcgctacat cttccagatg aaccgagaga
     1621 agaggaccga gctgaaagtc cagctgcccc atgctggcaa gtttgccctt aagatctttg
     1681 tgaagaagag gcaagaacaa ggtaacttcg tctttgtctt caactacctc ttgtgctgtg
     1741 ccaacaccaa ggtgaactgg cctatgttcc ccgagatcta cggccactgg ggacaggaca
     1801 atgagctgct agagcctctc tcgggggtgc ttcccgccaa ccgcaacata cccttcaaac
     1861 tgaagctgca tggcattgcc aaagctctgg tgaaagggca ggacacatgg cccctcaccc
     1921 tcaaccctga gggctactgg gagggcagct gcaacacggc cggctgccaa gaagtctatg
     1981 tcatggtgct agagaatgct aaccacaact tctacagtta catcctgaaa tacaaagtga
     2041 atgaccagtg agggaggaca gcattatcca cagtctccca gggctacggc cagcactgcc
     2101 cagggaggac ccaagataag tgcagagaga gcccaggaca ccactaatct gcatgaaatc
     2161 acttctaggc ctctgcctca gtcccctctg cctcggtctc cctgctctgc ctcaggcact
     2221 gaggaattca tgctgccgag ggctcactca gtgtggctgt ggattgaagg gacagaggca
     2281 agggccctct aaaaggaaaa ggtgctatgt aaacccaagg tattgtgaag tgtacgcccc
     2341 tgcctgtgcc tgctcttgtg ttcgttcata ctttggtgta gagctgggtg ggaaaggaaa
     2401 gtggaggtgt taccgctgct gaatgcttcc ctcaagatgc ctagagaatt ctcctccctg
     2461 ccccaacagt atgtgagcta ttagagaggt gtgtccccgc cccagtaaca tggtgttccc
     2521 cgatacttct ggaccccagg gaatgttggg cctgcccatc ttccacattc ctggtgcctc
     2581 tattagccac ttcatgctct tcacaaactt gtgaggggag ggtagaaaac aagctagctg
     2641 cccctcagcc aactgggggc tgttatctcc tgatccctag tgtctctgag atgtgataag
     2701 ggcagaaaaa cagccatgtg cacacatgga tgtcccggct agggaccagg gatggagtgt
     2761 ttttggaagt ccagcagccc acacgtaagg gtgaagatcc cagattctgc gtgcttagca
     2821 gagtttagct gagtgcctgg agatgccctt ccagccatca tcaggagcct caaatgccta
     2881 tgtagcctgt tgaagcctga ctgatgactg tgagtggaga cctgggctct gggcaagcag
     2941 atgagtctca acaggccaaa ccaagctgag gggaccacca ccctccccta gagaaagtgt
     3001 ttgtgcctgt ctctgagaaa agccccatca tagccatttt tgctcctgtg tctctgagat
     3061 aacaaccctg ccccaagctc aaccttccat tgggaacagt tgagggcctc ttacttgctt
     3121 ggacctgtcc taaaaaagcc tcaactgcct agctggccct cagcagcacc tgaggctggt
     3181 gtttccatgg caacagctga ggagtgagca ggcagcagca ggcagggaag gcctgaggaa
     3241 aaccccaaga ggctcctgca gtagcatccc acacaccgat gtgctccagg atgatcccca
     3301 ccaaacttct gggttctagg actctgccca ctgcacccat ctcaggactc ccacccctac
     3361 ccctcactgc tctctgagga atgtcctcaa gctcagctgc agccagagtc agcctgaggt
     3421 actcacagcc tctgcatcca attctttcct cagtaagagc ccatcagact cgttcagtaa
     3481 gtgactgacc cccgtgctgc atgctgggac tgtagagggg aacacaatgg actcagccat
     3541 aggcacccac acctctgggt gggcagtctg ccaagtgaag cccattcgaa gacctaggat
     3601 cccagaactt caattcctca ttcccttctg ccccttccct actgtcaccc acctgatacc
     3661 agatatcagt cctccaccag tctgggtagc ctcacttgtg attagcatag ctgctagggg
     3721 ctgagctgcc ttggcttgtg tccagggtcc tctggcagtc ttggcccatc agcatcttgt
     3781 cactcactcc tggaaaacgc acaaaagccc agtgggctga gaggtggggg tgtctcaact
     3841 acaaggcata ggcaccacca caagtaaacg atggagtttg cactgcctgg aaacagtctt
     3901 tcctcacccc tttgatgagc aggaagaagt gtgctatgtt ttaacgaaat agtaagtgct
     3961 tctgcgactc cctgccactc gctagacaca gccgcgacag ccactgctag ccctgaagaa
     4021 aagcaaaaaa aaaaaaaaaa aaaaatcccc atatttttca aaactgcata attaatccgt
     4081 tctggagctt gtagaggatg ctaccccaca aaacaggagc tgtcctcagc accagaaacc
     4141 cagacctggc gtctcccagt ggcccgggtc gtccacacgc ccctccctcc ttgtttaacc
     4201 aggcagcccc tttgtcaagg cagctgtagg tgcactcgaa aaaacgcctg catttctttt
     4261 tactgaagca aagatacatg aaactgaatc caatcttcat gaatttttac acgcatgctg
     4321 ctcaggctgg aaatttggag gttgcgtttt gaagcttttt tattcaaatc cccctctttg
     4381 tctgctggtc cacgagtccc attggccgat caaatggcac gagcgccccc ttgtggttat
     4441 gtgcgaagtt gccactgctg cgaaccccca agcaggatct ttctatgatt gttaaaaatc
     4501 actaggtgct ttcttgtccc ttgttcacga gttatgctgt ctacggcatc cacatcgtgg
     4561 atctgtcatc ctcgtcgtgg atacaccaag gtcagcgttg ccgtgcagac tgtgagaaga
     4621 ccctggtgag acttcctggc ctggcgtggt gagaagacat ggggtgcgat tgaaaattga
     4681 gcgccttgcc cagaaagcct ttccagagac agaaaccctg ggcacgggga tgcctggcta
     4741 gtgtcgctgt gatcacactt attactatgg caatgacagg ctgaaactga tcaaacttag
     4801 cattttgcca ggctggcccc aggatgggtg ccagggtgca gaaggacggg gcgtggtggg
     4861 gcaaaagggt gcaattaagc tcttttcggc ttgcttcaaa agtgccacca gctcagctgg
     4921 actgttctct gtctgattgt gaatattttg agttctccat atgttacatt gtcccaccag
     4981 gacagactcc tcccagccta cggagattag agagacataa atagattaac tgaagcatga
     5041 aggatttgag ctagatataa gaaccatttc ctgttgtgaa gtaggaggga cgcgttgcca
     5101 ataaactctg agaaattctc aaaggacttg aaaaggagaa aagttacccc agtggtccgg
     5161 ccttttcttt gccatattta ctgaagtggt tgggttctcc ctccgctaat tcttgaaccg
     5221 tactggttgg ccggcagtaa acaccaggtt aaggctgtga ccgcatagct cactactgtg
     5281 ggatgtcaga ggcagtttat ctgaggtctg aagtttcctt ttgtgtgaag taaaccgaca
     5341 gaggtgacta tttctcctga catgtgtgct gaattgtgtg ggccgctggc tgtcgaggat
     5401 gctgttgctg gagttctttt tcaataaaat ttatattcat ttttacccaa
//
