LOCUS       NM_001101675            1824 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus keratin 87 (Krt87), mRNA.
ACCESSION   NM_001101675 XM_001060532 XM_001060591 XM_001064518
VERSION     NM_001101675.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1824)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   2  (bases 1 to 1824)
  AUTHORS   Choi,H.I., Choi,G.I., Kim,E.K., Choi,Y.J., Sohn,K.C., Lee,Y.,
            Kim,C.D., Yoon,T.J., Sohn,H.J., Han,S.H., Kim,S., Lee,J.H. and
            Lee,Y.H.
  TITLE     Hair greying is associated with active hair growth
  JOURNAL   Br J Dermatol 165 (6), 1183-1189 (2011)
   PUBMED   21916889
REFERENCE   3  (bases 1 to 1824)
  AUTHORS   Nanashima,N., Akita,M., Yamada,T., Shimizu,T., Nakano,H., Fan,Y.
            and Tsuchida,S.
  TITLE     The hairless phenotype of the Hirosaki hairless rat is due to the
            deletion of an 80-kb genomic DNA containing five basic keratin
            genes
  JOURNAL   J Biol Chem 283 (24), 16868-16875 (2008)
   PUBMED   18420582
REFERENCE   4  (bases 1 to 1824)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Oct 22, 2022 this sequence version replaced NM_001101675.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB354637.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-411               JAXUCZ010000007.1  134433330-134433740 c
            412-620             JAXUCZ010000007.1  134431563-134431771 c
            621-681             JAXUCZ010000007.1  134430526-134430586 c
            682-777             JAXUCZ010000007.1  134429720-134429815 c
            778-942             JAXUCZ010000007.1  134429112-134429276 c
            943-1068            JAXUCZ010000007.1  134428805-134428930 c
            1069-1289           JAXUCZ010000007.1  134428195-134428415 c
            1290-1321           JAXUCZ010000007.1  134427467-134427498 c
            1322-1824           JAXUCZ010000007.1  134426567-134427069 c
FEATURES             Location/Qualifiers
     source          1..1824
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1824
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /note="keratin 87"
                     /db_xref="GeneID:681126"
                     /db_xref="RGD:1583565"
     exon            1..411
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1515
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /note="keratin complex 2, basic, gene 25; keratin 83, type
                     II"
                     /codon_start=1
                     /product="keratin, type II cuticular Hb3"
                     /protein_id="NP_001095145.1"
                     /db_xref="GeneID:681126"
                     /db_xref="RGD:1583565"
                     /translation="MSCFSSRLGASCGVRAFSCASACGPRPGRCCITAAPYRGISCYR
                     GLTGGFGSRSVCGAFRSGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDP
                     NAQCVKHEEKEQIKCLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNRKCCESNLEPLF
                     EGYIETLRREAEYVEADSGRLAAELNHVQEAMEGYKKRYEEEVALRATAENEFVALKK
                     DVDCAYLRKSDLEANAEALTQEIDFLRRLYEEETRLLHAHISDTSVIVKMDNSRDLNM
                     DCVVAEIKAQYDDIASRSRAEAESWYRTKCEEMKATVIRHGETLRRTREEMNELNRII
                     QRLTAEIENAKCQRAKLETAVAEAEQQGEAALTDARGKLTELEAALQKAKQDMACLLK
                     EYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVTCGGLTYGTT
                     PGRQIASGPSVTGGSISVMAPDSCSPCQPRASSFTCGSSRSVRFA"
     exon            412..620
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            621..681
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            682..777
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            778..942
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1068
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1289
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1321
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1824
                     /gene="Krt87"
                     /gene_synonym="Krt83"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcctggctc tgtatcgcct catcaccatg tcctgcttct cctcccgcct cggtgcctcc
       61 tgtggggtcc gcgccttcag ctgtgcctca gcctgtgggc cccgtcccgg ccgctgctgt
      121 atcactgcag ctccctacag gggcatctcc tgctaccgcg gactcacagg gggcttcggc
      181 agccgcagcg tctgtggggc cttccgctct ggctcctgtg gacgcagctt cggataccga
      241 tccggaggcg tctgcggacc cagccccccc tgcatcacca ccgtctctgt caacgagagc
      301 ctgctcaccc ccctcaacct ggagatcgac cccaatgctc agtgcgtgaa gcatgaggag
      361 aaggagcaga tcaagtgcct gaacagcagg ttcgcggcct tcatcgacaa ggtgcgcttc
      421 ctggagcagc agaacaagct gctggagacc aagtggcagt tctaccagaa ccgcaagtgc
      481 tgtgagagca acctggagcc tctgttcgag ggctacattg agacgctgag aagagaggct
      541 gagtatgtgg aggccgacag tggcaggctg gctgctgagc tcaaccatgt gcaggaggcc
      601 atggagggct acaagaagag gtatgaagag gaagtggcgc tacgggccac tgctgagaat
      661 gaatttgtgg ccctgaagaa ggatgtggac tgtgcctacc tccgtaaatc agacctggaa
      721 gccaatgcgg aagctctgac acaggagatc gacttcctgc gacgactgta cgaagaggag
      781 acacggctcc tccacgccca catctcagac acctccgtca tcgtcaagat ggacaacagc
      841 cgggacctga acatggactg cgtcgtggct gagatcaagg ctcagtacga tgacattgcc
      901 agccgcagcc gcgcagaggc cgagtcctgg taccgcacca agtgtgagga gatgaaggcc
      961 acagtgatcc ggcacgggga gaccctccgc cgcaccaggg aggagatgaa cgagctgaac
     1021 cgcatcatcc agaggctgac ggctgagata gagaacgcca agtgccagcg agcaaagctg
     1081 gagactgctg tggctgaggc agagcagcag ggagaggccg ccctcaccga tgcccgaggc
     1141 aagctgactg agctggaggc tgccctgcag aaggccaagc aggacatggc ctgcctgctc
     1201 aaggagtacc aggaggtgat gaactccaag ctggggctgg acatcgagat cgccacctac
     1261 aggcgcctgc tggagggcga ggagcacagg ctgtgtgaag gtgtgggctc tgtgaatgtc
     1321 tgtgtcagca gctcccgtgg aggagtcaca tgtgggggcc tcacttatgg cactacccca
     1381 gggcgccaga ttgcctctgg accctctgtc accgggggca gcatctcagt gatggcccct
     1441 gactcctgct ctccttgcca gccccgtgcc tccagcttca cctgtgggag cagccgctct
     1501 gtgcgctttg cttagtgcca gcaaatgagc cacctgtctg ccccagagtg gagtggtgtg
     1561 tgaatggaaa atgtgtgctt gcttgagaat cttctagatg ctcctgttag aggaaagagt
     1621 tcagggccac tctcctctgc cttctccttt tagggagttg tctcccagtt ctcctctggc
     1681 tttactttag aaggtcattc attcccaacc cgtcccttaa ccctaacatg tcttcaaata
     1741 cttgtaaatg atttgtatcg ttcaccaagc tctctgggac actaccagtc acccagggtg
     1801 acaataacac ttggccttct tggg
//
