LOCUS       NM_001008812            2603 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus keratin 84 (Krt84), mRNA.
ACCESSION   NM_001008812 XM_006242346 XM_235680
VERSION     NM_001008812.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2603)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
REFERENCE   2  (bases 1 to 2603)
  AUTHORS   Rogers,M.A., Winter,H., Langbein,L., Wolf,C. and Schweizer,J.
  TITLE     Characterization of a 300 kbp region of human DNA containing the
            type II hair keratin gene domain
  JOURNAL   J Invest Dermatol 114 (3), 464-472 (2000)
   PUBMED   10692104
REFERENCE   3  (bases 1 to 2603)
  AUTHORS   Tobiasch,E., Winter,H. and Schweizer,J.
  TITLE     Structural features and sites of expression of a new murine 65 kD
            and 48 kD hair-related keratin pair, associated with a special type
            of parakeratotic epithelial differentiation
  JOURNAL   Differentiation 50 (3), 163-178 (1992)
   PUBMED   1385239
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Dec 7, 2020 this sequence version replaced
            XM_006242346.3, NM_001008812.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN12840131 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-647               JAXUCZ010000007.1  134534962-134535608 c
            648-856             JAXUCZ010000007.1  134533732-134533940 c
            857-917             JAXUCZ010000007.1  134532964-134533024 c
            918-1013            JAXUCZ010000007.1  134532306-134532401 c
            1014-1178           JAXUCZ010000007.1  134531329-134531493 c
            1179-1304           JAXUCZ010000007.1  134531094-134531219 c
            1305-1525           JAXUCZ010000007.1  134530423-134530643 c
            1526-1557           JAXUCZ010000007.1  134529968-134529999 c
            1558-2603           JAXUCZ010000007.1  134527787-134528832 c
FEATURES             Location/Qualifiers
     source          1..2603
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2603
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /note="keratin 84"
                     /db_xref="GeneID:315320"
                     /db_xref="RGD:1359402"
     exon            1..647
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     CDS             66..1892
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /note="type II keratin Kb24; keratin 84, type II"
                     /codon_start=1
                     /product="keratin, type II cuticular Hb4"
                     /protein_id="NP_001008812.2"
                     /db_xref="GeneID:315320"
                     /db_xref="RGD:1359402"
                     /translation="MSCRSYRVSSGRRVGNFSSCSAMTPQHLNRFRASSVSCRSGPGF
                     RGLGGFGSRSVINFGSSSPRIAVGCSRPIRYGVGFGAGNGIAFGSGDGSGICLGYRAG
                     SGVGLGFGAGSCLGYGFGGPGFGGPGFGGPGFGYRIGGIGGPSAPAITAVTVNQSLLT
                     PLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQDQKCA
                     RSNLEPLFDNYITSLRRQLDVLVSDQARLQAERNHMQDILEGFKKKYEEEVVFRANAE
                     NEFVALKKDVDAAFLNKSDLEANVDALAQEIEFLKALYLEEIQLLQSHISETSVIVKM
                     DNSRDLNLDGIIAEVKAQYEEVARRSRADVESWYQTKYEEMRVTAGQHCDNLRNTRDE
                     INELTRLIQRLKTEIEHTKAQCAKLEAAVAEAEQQGEAALNDAKCKLTDLEGALQQAK
                     QDMARQLREYQELMNAKLALDIEIVTYRKLLEGEEIRICEGVGPVNISVSSSRGGVLC
                     GPESLVCGSGLSHSGGVTFSSSSGIRATGGILASSSLRAGGDLLSSGTRGGSVLVGDA
                     CAPSIPCALPTEGGFSSCSGGRGNRSSSIRFSSTTTSRRSRY"
     exon            648..856
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            857..917
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1013
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1178
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1304
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1525
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1557
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..2603
                     /gene="Krt84"
                     /gene_synonym="Kb24"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagactccc agctccggct caccccacac cacattgctc ctcagctgcc atctacaaag
       61 ccaccatgtc ttgccgctcc tacagagtca gctctggccg tcgagtggga aacttcagtt
      121 cttgctcagc aatgacccct cagcatctga accgcttccg ggcaagctct gtctcctgca
      181 ggagtggacc tggcttccgg ggcttgggtg gttttggtag tcggagcgtc atcaactttg
      241 gatcatcctc accccggata gcagtcggat gctctcgtcc tatccgctat ggagttggct
      301 ttggagctgg caatgggata gcctttggct ctggtgacgg aagtggcatt tgtctgggct
      361 atagggccgg cagtggcgtt ggcttgggtt ttggtgctgg cagttgcctt ggttatggtt
      421 ttggaggccc tggttttggt ggccctggct ttggtgggcc tggctttggc tacagaattg
      481 gaggaatcgg aggcccctca gcccctgcta tcacagctgt gactgttaac cagagcctgc
      541 tgacacccct caacctggag attgacccca atgcccagag ggtgaagaaa gatgagaagg
      601 aacagatcaa gaccctcaac aacaaattcg cctccttcat tgataaggta aggtttctgg
      661 agcaacagaa taaactccta gagaccaagt ggagcttcct ccaagaccag aaatgtgccc
      721 gtagcaacct ggagcctctc ttcgataact atatcaccag cctgcggagg cagctggatg
      781 tactagtcag cgaccaggct cggctgcagg cagagaggaa ccacatgcag gacatccttg
      841 agggcttcaa gaagaagtat gaagaagagg tggtgttccg ggctaatgcg gagaacgagt
      901 ttgtagcgct gaagaaggat gtagacgcag ctttcctgaa caaatctgac ctggaagcca
      961 acgtggatgc tctggcccag gaaattgaat tcctcaaggc tctgtacctg gaggaaatcc
     1021 agttgctgca gtcacacatc tcagagacat ctgtcattgt gaagatggac aacagccggg
     1081 acctgaacct ggatgggatc atagcggaag tcaaggcaca gtatgaggag gtagcaaggc
     1141 ggagtcgtgc agatgtggag tcctggtacc agaccaagta tgaggagatg cgggtgaccg
     1201 ctggccagca ctgcgacaat ctacgtaata cacgggacga gatcaatgag ctgacccggc
     1261 tgatccagag gctgaaaact gagatcgagc acaccaaggc tcagtgtgcc aagctggagg
     1321 ccgccgtggc tgaggcagag cagcagggtg aagccgccct caacgatgcc aagtgtaaac
     1381 tgactgatct ggagggagcc ctgcagcagg ccaagcagga catggccagg cagctgcggg
     1441 agtaccagga gctcatgaat gccaagctgg cgctggacat tgagattgtc acctacagga
     1501 agctgctgga gggcgaggaa atcaggatct gtgaaggtgt tgggccagta aacatatctg
     1561 tgagcagctc tcgaggaggt gtgctgtgcg ggcctgagtc cttggtctgc ggatccggcc
     1621 tttcccacag cggtggagtc accttctcca gcagcagtgg cattcgtgcc actggaggga
     1681 ttctggcttc ctcaagcctg agggctggtg gagacctgct gagttctggg accagaggag
     1741 gctcagtgct agtgggtgac gcctgtgccc ccagcatccc ctgtgcactg cctacagagg
     1801 gaggcttcag cagctgcagt ggtggtcgcg gtaacagaag ctccagcatc cgcttctcgt
     1861 ccaccaccac ctcccgtagg agcaggtact gagcacctag ccccaggggg ccgccgcctg
     1921 gagaagaacc agctgaacat cccctgttcc tatcccctga ggtgtataga ctctggtcct
     1981 gagggatctc cagaaactct ccctgccagt atacaaacct agcccatgtc cttgtgtaga
     2041 cacgccagtc ccagccccag gggcttctcc ccaattcctt tccttcagtt cctcggcagg
     2101 ctccagccac agtaaatgta ttttcagcac cacttcagaa agcagagcct cctggggaga
     2161 gaggggtcat tcagagcatg agcatgagca cagacccctg gggcctgcag gcatcctcag
     2221 cccatcccct tcctccctct tcccttccct ggcagaagat gcttcatagt ccctctcccc
     2281 tgtccccaaa ggacacacag tccttggtgg cccctaagtt cccatgatgg ttctcctccc
     2341 agtggctcat ccaggccatt tctcttaagg ttgttggttt gtctgcggta tatgggtctg
     2401 ccaagtaggt ggagttcaga cggagaggtg gtctcttctg ctccgtgtgc cttgtccttg
     2461 tggtgataga aggcccaact ctgggccctg tggttgccgc agggttgcgt ctgcaaactc
     2521 tgggagtctg ggggtgggtg ggcaactgtt tgtactattc tttgtattcc tgggttttca
     2581 ataaacttgc taagctaact tca
//
