LOCUS       NM_001389278            1736 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus keratin 83 (Krt83), mRNA.
ACCESSION   NM_001389278 XM_006242350
VERSION     NM_001389278.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Nanashima,N., Akita,M., Yamada,T., Shimizu,T., Nakano,H., Fan,Y.
            and Tsuchida,S.
  TITLE     The hairless phenotype of the Hirosaki hairless rat is due to the
            deletion of an 80-kb genomic DNA containing five basic keratin
            genes
  JOURNAL   J Biol Chem 283 (24), 16868-16875 (2008)
   PUBMED   18420582
REFERENCE   2  (bases 1 to 1736)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Dec 8, 2020 this sequence version replaced XM_006242350.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB355639.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN16676785,
                                           SAMN16676807 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-433               JAXUCZ010000007.1  134489168-134489600 c
            434-642             JAXUCZ010000007.1  134487704-134487912 c
            643-703             JAXUCZ010000007.1  134486494-134486554 c
            704-799             JAXUCZ010000007.1  134486271-134486366 c
            800-964             JAXUCZ010000007.1  134485589-134485753 c
            965-1090            JAXUCZ010000007.1  134485229-134485354 c
            1091-1311           JAXUCZ010000007.1  134484733-134484953 c
            1312-1343           JAXUCZ010000007.1  134483755-134483786 c
            1344-1736           JAXUCZ010000007.1  134482911-134483303 c
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1736
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /note="keratin 83"
                     /db_xref="GeneID:407759"
                     /db_xref="RGD:1303024"
     exon            1..433
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1510
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /note="type II keratin Kb23"
                     /codon_start=1
                     /product="type II keratin 23"
                     /protein_id="NP_001376207.1"
                     /db_xref="GeneID:407759"
                     /db_xref="RGD:1303024"
                     /translation="MTCGFQTGNFGCASACGPRPGRCCITAAPYRGISCYRGLSGGFG
                     SRSVCGAFRSGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKH
                     EEKEQIKCLNSRFAAFIDKVRFLEQQNKLLETKWQFFQNRKCCESNVEPLFEGYIETL
                     RREAECVEADSGRLAAELNHAQEAMEGYKKRYEEEVALRATAENEFVALKKDVDCAYL
                     RKSDLEANAEALTQEIDFLRRLYEEETRILHAHISDTSVIVKMDNSRDLNMDCVIAEI
                     KAQYDDIASRSRAEAESWYRTKCEEIKATVIRHGETLRRTREEINELNRIIQRLTAEI
                     ENAKCQNTKLEAAVTQSEQQGEAALTDARCKLAELEAALQKAKQDMACLLKEYQEVMN
                     SKLGLDIEIATYRRLLEGEEQRLCEGVGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV
                     CSAPCSGNVAVSTGLCAPCGSGPCHQGRC"
     exon            434..642
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            643..703
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            704..799
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            800..964
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1090
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1311
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1343
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1736
                     /gene="Krt83"
                     /gene_synonym="Kb23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccaggggac ataaggcctc agctccaagc actgtcaact tctctcctcg cacgtgtcct
       61 ctcctccacc atgacctgtg gctttcaaac tggaaacttc ggctgcgcct cagcctgtgg
      121 gccccgtccc ggccgctgct gcatcactgc agctccctac aggggcatct cctgctaccg
      181 cggactctca gggggcttcg gcagccgcag cgtctgtggg gccttccgct ctggctcctg
      241 tggacgcagc ttcggatacc gatccggagg cgtctgcgga cccagccccc cctgcatcac
      301 caccgtctct gtcaacgaga gcctgctcac ccccctcaac ctggagatcg accccaatgc
      361 tcagtgcgtg aagcatgagg agaaggagca gatcaagtgc ctgaacagca ggttcgcggc
      421 cttcatcgac aaggtgcgct tcctggagca gcagaacaag ctgctggaga ccaagtggca
      481 gttcttccag aaccgcaagt gctgtgagag caatgtggag cctctgttcg agggctacat
      541 cgagactctg aggcgggagg ctgagtgtgt ggaggccgac agcgggaggc tggctgctga
      601 gctcaaccat gcacaggagg ccatggaggg ctacaagaag aggtatgaag aagaagttgc
      661 actccgggcc acagcagaga atgagtttgt ggctctaaag aaggatgtgg actgtgccta
      721 cctgcgcaag tcagacctgg aggccaatgc agaggcactg acccaggaga tcgacttcct
      781 gaggcgactg tatgaggagg agacccgcat cctccacgcc cacatctcag acacctccgt
      841 catcgtcaag atggacaaca gccgggacct gaacatggat tgcgtcattg ctgagatcaa
      901 ggctcagtac gatgacattg ccagccgcag ccgcgcagag gccgagtcct ggtaccgcac
      961 caagtgtgag gaaataaagg ccacagtgat ccggcatgga gagaccctgc gtcgcaccag
     1021 agaggagatc aatgagctga acagaatcat ccagaggctg acagccgaga tcgagaatgc
     1081 caagtgccag aacaccaagc tggaggctgc tgtgacccag tctgagcagc agggagaggc
     1141 tgccctcacc gatgcccgct gcaagctggc tgagctggag gctgccctgc agaaggccaa
     1201 gcaagacatg gcctgcctgc tcaaggagta ccaggaggtg atgaactcca agctgggtct
     1261 ggacatcgag atcgccacct acaggcgcct gctggagggc gaggaacaga ggctgtgtga
     1321 aggcgtggga gccgtgaatg tgtgtgtcag cagctcccgt ggtggagttg tgtgcgggga
     1381 cctctgtgtg tctggttcaa ggcctgtgac aggcagtgtc tgcagtgccc catgcagcgg
     1441 gaatgtggca gtgagcacag gcctgtgtgc accctgtgga agtggcccct gtcaccaggg
     1501 gaggtgttag gagtcaagag ggagccatga agcagcctgg cctacaaggc tgacctcgga
     1561 ggcctcaagg tctgttgccc atcctcagta gctgcccctc cagctacctg ctggcaaggg
     1621 gcttgctgct gatagatcag cctcctgcct cagctgcagc cctgggaata cccagtgctg
     1681 cttcctgcac ctctggcctc tagaccctgc tgtgcaataa actgtgctga ctctca
//
