LOCUS       NM_001008815            3058 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus keratin 80 (Krt80), mRNA.
ACCESSION   NM_001008815 XM_235674
VERSION     NM_001008815.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3058)
  AUTHORS   Langbein,L., Eckhart,L., Rogers,M.A., Praetzel-Wunder,S. and
            Schweizer,J.
  TITLE     Against the rules: human keratin K80: two functional alternative
            splice variants, K80 and K80.1, with special cellular localization
            in a wide range of epithelia
  JOURNAL   J Biol Chem 285 (47), 36909-36921 (2010)
   PUBMED   20843789
REFERENCE   2  (bases 1 to 3058)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Oct 12, 2022 this sequence version replaced NM_001008815.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.33357.1,
                                           SRR26643295.30295.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840130,
                                           SAMN16676784 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-408               JAXUCZ010000007.1  134363465-134363872 c
            409-617             JAXUCZ010000007.1  134358003-134358211 c
            618-678             JAXUCZ010000007.1  134352964-134353024 c
            679-774             JAXUCZ010000007.1  134352311-134352406 c
            775-939             JAXUCZ010000007.1  134345960-134346124 c
            940-1065            JAXUCZ010000007.1  134345442-134345567 c
            1066-1286           JAXUCZ010000007.1  134344758-134344978 c
            1287-1342           JAXUCZ010000007.1  134343800-134343855 c
            1343-3058           JAXUCZ010000007.1  134341956-134343671 c
FEATURES             Location/Qualifiers
     source          1..3058
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..3058
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /note="keratin 80"
                     /db_xref="GeneID:315318"
                     /db_xref="RGD:1359177"
     exon            1..408
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..1467
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /note="K80; CK-80; cytokeratin-80; type II keratin-20;
                     type-II keratin Kb20; keratin 80, type II"
                     /codon_start=1
                     /product="keratin, type II cytoskeletal 80"
                     /protein_id="NP_001008815.1"
                     /db_xref="GeneID:315318"
                     /db_xref="RGD:1359177"
                     /translation="MAYRSCVVGFSSHSGCEVTPAGSSQPGTSGWGSCGLPGPGFSSR
                     SLTSCRPAGVIPKVTVNPSLLVPLDLKVDPAVQQQKNQEKEEMKVLNDKFASLIGKVQ
                     ALEQRNQLLETRWGFLQGQGSATFDLSHHYETFQGRLQEELRKVSQERGQLEASLLQV
                     LEKVEEFRVRYEDEISKRTDLEFTFVQLKKDLDAECLRRTELETKLKGLQGFVELMRT
                     VYEQELKDLTAQVKDVSVTVGLDSRCHIDLSGIVEEVKAQYDAIAARSLEEAEAYSRS
                     QLEERAARSAEFGNSLQSSRCEIADLNVRIQKLRSQIVSVKSHCLKLEENIKVAEEQG
                     ELAFQDAKDKMAQLEAALQKAKQDMARQLREYQDLMNTKLALDIEIATYHKLMEGEES
                     RMDLPSTTVVSAVQSRCRTTASKSGLSKTPSRKKKNRGGPVIKITEMSEKYLSQESEA
                     SE"
     exon            409..617
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            618..678
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            679..774
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            775..939
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1065
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1286
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1342
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..3058
                     /gene="Krt80"
                     /gene_synonym="Kb2; Kb20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtccccagc cggccctgga tgtgacagga ggcagctgcc agccaccaac tccaaagctt
       61 cctagctcgc tggtgagccc tccggctccc aggcccaggg gggccaccat ggcctaccgc
      121 tcctgcgtcg ttggcttcag tagccacagt ggctgtgagg tgacccctgc gggtagttcc
      181 cagcctggga cctcaggatg gggcagctgt gggctccctg ggcctggctt cagctctcga
      241 agcctcacaa gctgtaggcc agctggtgtc atccccaagg tgactgtgaa ccccagcctg
      301 ctggtgcctc tggacctcaa ggtggatcca gctgttcagc agcagaagaa ccaagagaag
      361 gaggagatga aggttctcaa tgataaattt gcctccctca ttggcaaggt acaagctctg
      421 gagcagcgca accaactgct ggagacccgg tggggcttcc tgcagggcca gggatcagcc
      481 accttcgacc tcagccacca ctacgagaca ttccagggcc ggctgcaaga ggaactccgc
      541 aaagtgagcc aggagcgggg acaactggag gccagcctgc tgcaggtgct agagaaggtg
      601 gaggagttcc gcgtcaggta cgaggatgag atctccaagc gcacagacct ggaatttacc
      661 tttgtccagc tgaagaagga cctggatgct gagtgtctcc gacgaactga actggaaacc
      721 aaactcaagg gcctgcaggg tttcgtagag ctgatgagga cagtctatga gcaggagctg
      781 aaagacctta cagcccaagt gaaggacgtg tcggtcaccg tgggcctgga cagccgctgc
      841 cacatcgacc tgagcggcat cgtggaggaa gtgaaggccc agtacgatgc catcgctgct
      901 cgaagcctgg aggaggctga agcctattca cggagccaac ttgaggagcg agctgcccgc
      961 tcagcggagt tcgggaacag cctccagagc agccgctgtg agattgcaga cctcaacgtg
     1021 cgcatccaga agctgcggtc acagatcgtc tcagtcaaga gccattgcct gaaactggag
     1081 gagaacatca aggtggccga ggaacaagga gagctggcct tccaggacgc caaggacaag
     1141 atggcccagc tggaggctgc cctgcagaag gccaaacagg acatggcccg gcagctgcgc
     1201 gagtaccagg atctcatgaa caccaagctg gctctggaca tagagatcgc cacctaccac
     1261 aagctgatgg aaggagaaga aagccggatg gacctgcctt ccaccactgt ggtcagtgct
     1321 gtgcaatccc gatgcagaac cactgcttcc aagtctggcc tctccaagac cccctcccgg
     1381 aagaagaaga accgcggagg cccagtgatc aaaatcactg aaatgtcaga gaaatacctc
     1441 tcccaggagt cggaggcctc cgagtaagac agccacccca ggaagagcct caagtcactt
     1501 ccactgcagc cgacttaagc taaactcaag agcggagcct ggagccttga gggaggagga
     1561 gagatatgga actgggagaa gtgggttcca gctgagaccc ggtttctctg gacagtcagc
     1621 gaaggcaggg agagctgaca gctccattct tcactggtgt ctcacttgcc atctccagcc
     1681 tcctggccac agcttgtcct ggcaggcaaa ggggagcttg ggacctgccg cctctccact
     1741 cctctgaagc tcctcttccc atagagctct gacaaggtgc ttgacttttg cccactgctt
     1801 gccctgactt ctgcctcagc cttgccttgc ctctgcctca aaaccgaggc tggcatcctc
     1861 accaactagc caggacacag tcggggctga agggtatact cggattttgt cccatatacg
     1921 gtgtgcctgg gcctgggggc tgaagacccc tagatcccct gccttcaggc ttcccagaca
     1981 cctgacagta ttgggggatg aaggaaggaa aagcctgatg tgttagacaa aagcctgagc
     2041 cgcagaatgg ccccaatgca ccctcttcta gggactaaga tgtcataact gacctcaaag
     2101 ctattccaac caaggctaac accctaggag cagaatccag agataagagc ctaacaccag
     2161 gcctagcctt cccctccctg ccattctggg ttgtgccacc atcccaaaat ctgggctctc
     2221 cttccagccc aggtctctcc aacctcaaca cgtgtctttg gaacagcatg cactagagcc
     2281 ccagagccct ccctgccaga aatgcccact tgccccaaat ctcactccct gggtcctctg
     2341 ttctatcccc taagacatcc cactcagtgg atcagttctc ccccttctgt ctctcccttc
     2401 ctccaagttt actccccctg cctctggtag gtcataaaga aggctaagcc tgggaagatc
     2461 tggaagtttc ttagacgtaa atttggtccg ggaagcatca acaaaggcct tcaagcactg
     2521 catccaccaa gggtgtctgt gtgttcccgc cctggctctc acctctgcgg tttgcggagc
     2581 acagcagtgg cagcctcccc atgccaccag cctcgttctc gactcccttt atccccgaga
     2641 cccatgtcct ggctcctgcc tcacctcctc tcctagcctg tctcccaccc ctgcatctca
     2701 ttctctcaga ccaggtatcc tcaaggccgc tggcccgcca ggcctgcagg gagtgcccgt
     2761 aggctaccta ctctcccagg acaaaggaac ccagcaatat acttaaccta gagttcccga
     2821 agcaggtgct cattgctgct ctctctcggg ctatttatct gtttccaagg gacatgaaat
     2881 atagaacgta tatattattt tttcataact tatgtggctt ttaacttatt gcttccctcc
     2941 ctgtttctgc atgataattg ctgagcgagc tatcaggatc ttagagaagt cattccagct
     3001 gcctacttgg ctgatgactc gggcaagggg tgaataaaac actgagattc atccacgg
//
