LOCUS       NM_001008807            2964 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus keratin 77 (Krt77), mRNA.
ACCESSION   NM_001008807 XM_006242435
VERSION     NM_001008807.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2964)
  AUTHORS   Langbein,L., Rogers,M.A., Praetzel,S., Cribier,B., Peltre,B.,
            Gassler,N. and Schweizer,J.
  TITLE     Characterization of a novel human type II epithelial keratin K1b,
            specifically expressed in eccrine sweat glands
  JOURNAL   J Invest Dermatol 125 (3), 428-444 (2005)
   PUBMED   16117782
REFERENCE   2  (bases 1 to 2964)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Dec 8, 2020 this sequence version replaced
            XM_006242435.3, NM_001008807.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.30381.1,
                                           SRR26360194.1548481.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-638               JAXUCZ010000007.1  134880139-134880776 c
            639-853             JAXUCZ010000007.1  134875699-134875913 c
            854-914             JAXUCZ010000007.1  134874626-134874686 c
            915-1010            JAXUCZ010000007.1  134874062-134874157 c
            1011-1175           JAXUCZ010000007.1  134873082-134873246 c
            1176-1301           JAXUCZ010000007.1  134870953-134871078 c
            1302-1522           JAXUCZ010000007.1  134870623-134870843 c
            1523-1557           JAXUCZ010000007.1  134870247-134870281 c
            1558-2964           JAXUCZ010000007.1  134868416-134869822 c
FEATURES             Location/Qualifiers
     source          1..2964
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2964
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /note="keratin 77"
                     /db_xref="GeneID:406226"
                     /db_xref="RGD:1302968"
     exon            1..638
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1826
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /note="type II keratin Kb39; cytokeratin-1B; keratin 77,
                     type II"
                     /codon_start=1
                     /product="keratin, type II cytoskeletal 1b"
                     /protein_id="NP_001008807.2"
                     /db_xref="GeneID:406226"
                     /db_xref="RGD:1302968"
                     /translation="MSRQFSSQSAFSSRSRRVYSTRSSSGFGGGRQILVSVGQSRRCG
                     GDYGGGFSSRSLYSLGGSKSIFGGLVGRSASGFCQSRGAGGGFGGGFGGGRSFGGGGF
                     GGGYGGGGRFGGGFGGGFGTSNFGLGGFGPSYPPGGIHEVTVNQSLLEPLHLEVDPEI
                     QKIKTQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTRTSSLEPIF
                     EEFINQLQRQVDVLTNEQLRQNSEIRSMQDIVEDYKNKYEDEINKRTNSENDFVVLKK
                     DVDAAFMAKSDLQSRVDTLYGEINFLKYLFDTELSQIQTHVSDTNVILSMDNNRSLDL
                     DSIINAVRTQYELIAQKSKDEAEALYQTKYQELQITAGKHGDDLKNSKMEISELNRNA
                     QRLQAEIANIKKQIEQMHGSISDAEERGERALQDAKQKLQETEEALQQMKEDLARLLR
                     DYQALLGAKLSLDVEIATYRELLEGEESRMSGALQSQVSISVQSSQVTIGGGGGSGGY
                     GGGSSRGGGGGGGSSRGGGGGTGSRGGGGSGGGGSYGSSSRSSSKYSGGGSSSRTQIL
                     QTSTHTSRRHVVE"
     exon            639..853
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            854..914
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1010
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1175
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1301
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1522
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1557
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
     exon            1558..2964
                     /gene="Krt77"
                     /gene_synonym="CK-1B; K77; Kb39"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagagagtca cagctcctgc agtccctgct ctctgtctcc ttttgctggg cctttgctac
       61 ctgtgcctct ggttgcccta gcaaccatga gccgccagtt cagttctcag tctgcattta
      121 gctctaggag caggagggtc tatagcacca ggtcttcatc aggctttggg ggtgggagac
      181 agattctggt gtctgtgggt cagtcgagga ggtgtggagg tgattatggt ggtgggttca
      241 gttccaggag tctctatagt ctgggtggta gtaaaagcat ctttgggggc ctagtggggc
      301 gaagtgccag tggtttctgc cagagtagag gggcaggagg aggattcgga ggaggatttg
      361 ggggaggaag aagctttggt ggaggtggct ttgggggtgg ctatggtgga ggtggcagat
      421 ttggaggtgg ttttgggggc ggatttggca ctagcaattt tgggcttggt ggcttcggtc
      481 cttcttatcc tcccgggggc atccatgagg tgactgttaa ccagagtctc ctggagcccc
      541 ttcacctaga agtggatcct gaaattcaga agatcaagac ccaggagagg gagcagatca
      601 agactctcaa caacaagttt gcctccttca tcgacaaggt gcgcttcctg gagcagcaga
      661 accaggtgct gcagaccaaa tgggagctgc tgcagcaggt gaacacgtct actcggacca
      721 gcagcctgga gcccatcttt gaggagttca tcaatcagct gcagaggcag gtggatgttc
      781 tgaccaatga gcagttgcgc cagaactcag agatcaggag catgcaggat atcgtggagg
      841 actacaagaa caagtatgag gatgagatca acaaacggac caattcagag aatgactttg
      901 ttgttttgaa aaaggacgtg gatgctgctt tcatggccaa atcagacttg cagtccagag
      961 tggacacgct gtacggggag atcaacttcc tgaaatatct atttgatacg gagctgtccc
     1021 agatacaaac ccatgtcagt gataccaatg tcatcttgtc aatggacaat aaccgctcct
     1081 tggacttgga cagcatcatc aatgcagtgc gcacccaata tgaattaatt gcacagaaga
     1141 gcaaagacga ggctgaggca ctgtaccaaa ccaagtacca agagctgcag atcacagctg
     1201 gcaaacatgg agatgacctg aagaatagca agatggagat ctcagagctt aaccgcaatg
     1261 cccagaggct gcaggcagag atcgccaaca tcaagaagca gatcgaacag atgcatggat
     1321 ccatttcgga tgcagaggag aggggagaaa gagctctcca ggacgccaag cagaagctgc
     1381 aagaaacgga agaggccttg cagcagatga aagaggacct ggctaggctg ctgagagatt
     1441 accaggcact gctgggtgcc aagctgtcct tggatgtgga gatcgccacc taccgcgagc
     1501 ttttggaggg cgaggagagc aggatgtcgg gggctctgca gagtcaagtg agcatctcgg
     1561 tgcagagtag ccaggtgacc attggcggcg gcggcggctc aggaggttat ggcggcggca
     1621 gttcgcgagg aggcggtggt ggcggcggca gctcccgcgg aggtggagga ggaacaggct
     1681 cccgcggggg aggcggcagc ggaggcggcg ggagctatgg ctccagcagc agaagcagca
     1741 gcaaatacag cggcggtggc agctcctccc gcacgcagat actgcagacc tccacccaca
     1801 cctcgcgcag gcacgtggtg gagtagcagc cggggcccct gcacttctag ggtcttttcc
     1861 cccaatccct cccggactcc ctcgcctatc ttttcccaat gggtcccagc aagtttctag
     1921 gtgactcaga ctctaggaag agacagacac atgctcactc agtcatccct ctgctggtct
     1981 tgctactgtc ctgatcctca ggggctttgc ccagcaatga aggaaatgat cttggtgaac
     2041 gacttcactg agatcctcag tcccaggtcc ccgttcctaa actgggctgc tagtaaataa
     2101 taacccaccc cgcagcggcc tactgcaatc attattccaa ggcaagttta cttagtgagg
     2161 gggaggtctg agccaagagc cttcggggcc actcatgctc tttcaccatg acagcatggg
     2221 taggcttgtt gttctgattc ggtacctgta ggccatacct gtgctgacct gtgttatccc
     2281 ctggttaaca gtcctgccgg gatatttcag ttggtatggg gacttaagtc cttgtcagag
     2341 gaagactgtc cttagcagtg ggtggggata ggataaggta gtcaatcaag ttctgtttct
     2401 gtcctctccc tttccagcag ccccttgcat ttagagccaa ccccttcctg aatcccactc
     2461 caaaaggctc tgatgagaac acgggcacct gcagggcagc cccactccat gcaagtgtct
     2521 gggcctgggg aatgagagtt gcagccttat gtcaatctgg aaatggcctg ggtatttgca
     2581 aacaagccaa gactcatttt cagatctcct ttgtcccttg tgttctgatt ccgagcacct
     2641 tgtcagactt cgtctcctaa tttaaaattt aatttacagt tctatgaaaa atacttgagc
     2701 tgtgctgagg gggcaggaag aggaaagtgc cagccaatga gcagtcatga gagagggaat
     2761 gctcctttgc ttcctgttcc gaggaccctt tcacttgctt gcctagtccc tacaaccgct
     2821 gagtctataa ttctgtccgg gagagcttct ccacaggtgc tgctgggtaa tgcttgtgac
     2881 ctcatttcct ggttggaagc ttaactctga agggcttggc agttctgttt tttcctacaa
     2941 taaatttctc ttgtgatctc cgta
//
