LOCUS       NM_001008805            2283 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus keratin 76 (Krt76), mRNA.
ACCESSION   NM_001008805
VERSION     NM_001008805.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2283)
  AUTHORS   DiTommaso,T., Jones,L.K., Cottle,D.L., Gerdin,A.K., Vancollie,V.E.,
            Watt,F.M., Ramirez-Solis,R., Bradley,A., Steel,K.P., Sundberg,J.P.,
            White,J.K. and Smyth,I.M.
  CONSRTM   WTSI Mouse Genetics Program
  TITLE     Identification of genes important for cutaneous function revealed
            by a large scale reverse genetic screen in the mouse
  JOURNAL   PLoS Genet 10 (10), e1004705 (2014)
   PUBMED   25340873
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2283)
  AUTHORS   Liakath-Ali,K., Vancollie,V.E., Heath,E., Smedley,D.P., Estabel,J.,
            Sunter,D., Ditommaso,T., White,J.K., Ramirez-Solis,R., Smyth,I.,
            Steel,K.P. and Watt,F.M.
  TITLE     Novel skin phenotypes revealed by a genome-wide mouse reverse
            genetic screen
  JOURNAL   Nat Commun 5, 3540 (2014)
   PUBMED   24721909
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2283)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 2283)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Oct 13, 2022 this sequence version replaced NM_001008805.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.1584092.1, BK003994.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760476 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-589               JAXUCZ010000007.1  134903574-134904162 c
            590-810             JAXUCZ010000007.1  134902562-134902782 c
            811-871             JAXUCZ010000007.1  134900795-134900855 c
            872-967             JAXUCZ010000007.1  134900334-134900429 c
            968-1132            JAXUCZ010000007.1  134899704-134899868 c
            1133-1258           JAXUCZ010000007.1  134899486-134899611 c
            1259-1479           JAXUCZ010000007.1  134898638-134898858 c
            1480-1514           JAXUCZ010000007.1  134897067-134897101 c
            1515-2283           JAXUCZ010000007.1  134895677-134896445 c
FEATURES             Location/Qualifiers
     source          1..2283
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2283
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /note="keratin 76"
                     /db_xref="GeneID:407757"
                     /db_xref="RGD:1303078"
     exon            1..589
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..1807
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /note="type II keratin Kb9; keratin 76, type II"
                     /codon_start=1
                     /product="keratin, type II cytoskeletal 2 oral"
                     /protein_id="NP_001008805.1"
                     /db_xref="GeneID:407757"
                     /db_xref="RGD:1303078"
                     /translation="MSRQACKKSFSCGSQGFSGRSAVVSGSSRSSCVARSGAASGGAC
                     GFRGGAGTFGSHSLYNLGGSKSISISVAGGFSGGRSSCGSGFGSGYGGSFGSSRGMGG
                     GFGGASGFGGAGGFGRPGGFGPGGCPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQER
                     EQIKILNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTRSGSGPLNLESFFESYISC
                     LRKQLDSLLGAKGSLQGELKSMQDLVEDFKRKYEEEINRRTTAENEFVALKKDVDGAY
                     MSKVELQAKVDSLTDEINFLRTLYDMELSQMQSHISDTSVVLSMDNNRCLDLDSIIAE
                     VKAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRSTKSEIMELNRTIQRLRAE
                     IENVKKQNTNLQASIAEAEQRGERALKDADAKFQDLQAALQKAKEDLARLLREYQELM
                     NVKLALDVEIATYRKLLEGEECRLSGEFQNAVSISVVSNVTSTSSSGGYRGAGGSNYG
                     GDSSGRSSSSIGSRGSSGSRLGSGGSISVSQQRTSFNSGGSQTSVGSCYKSGRGGTSS
                     VHFSQTTSSSQQRSK"
     exon            590..810
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            811..871
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            872..967
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1132
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1258
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1479
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1514
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..2283
                     /gene="Krt76"
                     /gene_synonym="Kb9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcctctcct cagtcctttg ctctgctaag ttatcgctag ctcactgcca cactcctcgc
       61 tatgagcaga caagcctgca agaaatcctt cagctgtggg agccagggat tctctggccg
      121 ctcagctgtg gtttctggca gcagcaggag cagctgtgtg gctcgctctg gggcagccag
      181 tggaggggct tgtgggttcc ggggcggagc gggtaccttt ggcagtcaca gcctctacaa
      241 cctgggtggc agcaagagta tctctatcag tgtggctggt ggcttcagtg gagggcgtag
      301 cagctgtggc agtggctttg gaagtggcta tggaggtagc tttggtagca gcagagggat
      361 gggaggtggc tttgggggag cttctggatt tgggggagct ggtggctttg gtaggcctgg
      421 tggctttggc cctggtggct gccctggggg aatccaggaa gtgaccatca accagagcct
      481 cctgcagccc ctcaatgtgg agattgaccc ccagattggg caagtgaagg cccaggagcg
      541 tgaacagatc aagatcctca acaacaagtt tgcctccttc attgacaagg tgcgcttcct
      601 ggagcagcag aacaaggtcc tggagactaa gtgggagttg ctgcagcagc agaccacacg
      661 ctctggctcc ggccccctga acctggaatc tttcttcgag tcttacatca gctgtttgcg
      721 caagcagtta gattcacttc tgggggcgaa ggggagcctg cagggagagc tgaagagcat
      781 gcaagacctg gttgaagact tcaaaaggaa gtacgaggag gagatcaaca ggcgcaccac
      841 tgcagagaat gaattcgtag cactgaagaa ggatgtggat ggagcttaca tgagcaaggt
      901 ggagctgcag gcgaaggtgg acagcctgac tgatgaaatc aactttctga ggacgctcta
      961 tgacatggag ctgtctcaga tgcagagcca catcagtgac acctctgtgg tcctgtccat
     1021 ggacaacaac cgctgcttgg acctggacag catcatcgct gaggtcaagg cccagtatga
     1081 ggacattgct cagaggagta aggctgaggc tgaggccctg taccagacca agcttgggga
     1141 gttacagacc acagctggca ggcacggaga tgacctgagg agcaccaaga gcgagatcat
     1201 ggagctcaac aggacgatcc agagactgcg agcagagatt gagaatgtca agaagcagaa
     1261 caccaacctg caggcgtcca ttgcagaggc tgagcagcgt ggtgagcggg ccctcaagga
     1321 tgcagatgcc aaattccaag acttgcaggc tgctctgcag aaggccaagg aggacctggc
     1381 ccggctgctg cgcgagtacc aggagctgat gaacgttaag ctggccctgg atgtggagat
     1441 cgctacctac aggaagctgc tggagggtga agagtgcagg ttgtctggag agtttcagaa
     1501 tgctgtgagc atttcggtgg tcagcaatgt taccagcaca agcagcagcg gaggctacag
     1561 aggggccggt ggcagcaact acggaggaga cagcagtggc agaagcagca gcagcatcgg
     1621 cagcaggggc agcagtggga gcaggcttgg cagcggaggc agcatctccg tgagccagca
     1681 gagaacgagc tttaactctg gtggcagcca gacctcggta ggcagctgct acaagtctgg
     1741 cagagggggc accagcagtg ttcacttctc tcagaccacc agttccagcc agcaacgctc
     1801 caagtgatct tcaggggcaa aacattccca ccctcctgct ttcccagcct tagcctgcaa
     1861 tggcgtccgc tctcatcttc ttggcaccaa caggtgcaca gttcaactct gctttaactt
     1921 gagttccttg gagaaggggc tgaactcttt gctcctatat ctttaagtct cctcttaggt
     1981 cgaggtggtc cagctacaac tagtctggga tgatggtgct cctggagaag agcctgtgat
     2041 gaaattgaaa tgtggacagc aacacccaag gctgagcctt cctgagccct ctagtctagc
     2101 ctagtccatt ccggctatct gtctctcaca ggtgaaaggg tcaaggtttc caaactgttg
     2161 gatcttatgg atcgctcccc acagctggct catctactcc cttaaagcct tccgagctgt
     2221 gggtcctttg ctcatggaaa gctatactcc cttttctcaa taaattgcag cgtgcttcac
     2281 aaa
//
