LOCUS       NM_001008819            1542 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus keratin 33B (Krt33b), mRNA.
ACCESSION   NM_001008819 XM_579216
VERSION     NM_001008819.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1542)
  AUTHORS   Ma,Y.M., Wu,K.J., Dang,Q., Shi,Q., Gao,Y., Guo,P., Xu,S.,
            Wang,X.Y., He,D.L. and Gong,Y.G.
  TITLE     Testosterone regulates keratin 33B expression in rat penis growth
            through androgen receptor signaling
  JOURNAL   Asian J Androl 16 (6), 817-823 (2014)
   PUBMED   24994782
  REMARK    GeneRIF: reveals a novel mechanism facilitating penis growth after
            testosterone treatment in precastrated prepubescent animals, in
            which androgen enhances the expression of AR protein as well as its
            target genes, such as Krt33b
REFERENCE   2  (bases 1 to 1542)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 31, 2022 this sequence version replaced NM_001008819.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK004038.1, SRR26643295.40678.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16418971 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-348               JAXUCZ010000010.1  85461729-85462076   c
            349-431             JAXUCZ010000010.1  85460050-85460132   c
            432-588             JAXUCZ010000010.1  85459035-85459191   c
            589-750             JAXUCZ010000010.1  85458070-85458231   c
            751-876             JAXUCZ010000010.1  85457854-85457979   c
            877-1097            JAXUCZ010000010.1  85457422-85457642   c
            1098-1542           JAXUCZ010000010.1  85456241-85456685   c
FEATURES             Location/Qualifiers
     source          1..1542
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1542
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /note="keratin 33B"
                     /db_xref="GeneID:450227"
                     /db_xref="RGD:1359595"
     CDS             1..1215
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /note="type I hair keratin KA28"
                     /codon_start=1
                     /product="keratin, type I cuticular Ha3-II"
                     /protein_id="NP_001008819.1"
                     /db_xref="GeneID:450227"
                     /db_xref="RGD:1359595"
                     /translation="MSYNCCLPALSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNC
                     NWFCEGSFNGNEKETMQFLNDRLASYLEKVRQLERENAELESRIQERSQQQDPLVCPA
                     YQAYFRTIEELQQKILCGKSENARLVVQIDNAKLAADDFRTKYESELSLRQLVESDIN
                     GLRRILDELTLCKSDLEAQVESLKQELLCLKQNHEEEVNTLRCQLGDRLNVEVDAAPT
                     VDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELR
                     RTVNALEIELQAQHNLRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLER
                     QNQEYQVLLDIRARLECEINTYRGLLENEDCKLPCNPCATTNACDKPIGPCVTNPCVT
                     RPRCGPCGTFGC"
     exon            1..348
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
     exon            349..431
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
     exon            432..588
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
     exon            589..750
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
     exon            751..876
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
     exon            877..1097
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1542
                     /gene="Krt33b"
                     /gene_synonym="Ka28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtcataca actgctgcct gcccgccctg agctgccgca ccagctgctc ctccaggccc
       61 tgcgtgcccc ccagctgcca tggctgcacc ctgcccggag cctgcaacat ccccgccaat
      121 gtgggcaact gcaattggtt ctgtgagggc tccttcaatg gcaatgagaa ggagaccatg
      181 cagttcctga atgaccgcct ggcctcctac ctggagaagg tgaggcagct ggagagagag
      241 aatgcagagc tggaaagcag gatccaggag aggagccagc agcaggaccc cctggtgtgc
      301 cccgcctacc aggcctactt caggaccatc gaggagctgc agcagaagat tctctgtggc
      361 aagtccgaga acgccaggct ggtggtgcag atcgacaacg ccaagctggc tgctgatgac
      421 ttcaggacca agtatgagtc ggagctgtct ctgaggcagc tggtggagtc agatatcaac
      481 ggcctgcgca ggatcctgga cgagctgact ctgtgcaagt ctgacctgga ggctcaggtg
      541 gagtccctga agcaggagct gctgtgtctc aagcagaacc acgaggagga agtcaacacc
      601 ctgcgctgcc agcttggaga ccgcctcaac gtcgaggtgg acgctgctcc cactgtggac
      661 ctgaaccgtg tgctcaatga gaccaggtgt cagtacgagg ccctggtgga aaccaaccgc
      721 cgggaagtgg aggaatggtt caccacacag actgaggagc tgaacaagca ggtggtgtcc
      781 agctcagagc agctgcagtc ctgccaggcc gagatcatcg agctgagacg cacagtcaat
      841 gccctggaga tcgagctgca ggcccagcac aacctgagaa actctctgga gaacaccctg
      901 acagagagtg aggctcgcta cagctcccag ctatcccagg tgcagtgcct gatcaccaac
      961 gtggagtccc agcttggtga gatccgggct gacctggagc gtcagaacca ggagtaccag
     1021 gtgctgctgg acatccgggc caggctggag tgtgagatca acacatacag gggtctgctg
     1081 gagaacgaag actgcaagct gccctgcaac ccctgtgcca ccaccaatgc ctgtgacaag
     1141 cccattggac cctgtgtcac aaatccttgt gtcacacgcc cccgatgtgg accctgcggt
     1201 acctttggct gctaaatacc ctgaggccag caggaggatt gcatgaagtc agaaagaaag
     1261 ctggtggatc agctcagcct ctttgaatcc acatccagca ccttaaggat catggtctgg
     1321 aagaagaaca aaggccctag tgctgtggtc tgtttctgag tccaggccca ctggaccatc
     1381 ttcatccagg gcttctctgt gatcacccct gctcctgttc tggtggttta aaaggtctga
     1441 gctgtgaagg ggccacacaa ggtattttgt ggttctcact gcttcttcta ccctttcttg
     1501 cagttttcca aaaacctaat aaattttcct cttgcaaaca ga
//
