LOCUS       NM_001008757            1688 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus keratin 33A (Krt33a), mRNA.
ACCESSION   NM_001008757 XM_220966
VERSION     NM_001008757.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1688)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   2  (bases 1 to 1688)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 27, 2022 this sequence version replaced NM_001008757.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK004037.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760475,
                                           SAMN06621351 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-414               JAXUCZ010000010.1  85447534-85447947   c
            415-497             JAXUCZ010000010.1  85446475-85446557   c
            498-654             JAXUCZ010000010.1  85445823-85445979   c
            655-816             JAXUCZ010000010.1  85444308-85444469   c
            817-942             JAXUCZ010000010.1  85444092-85444217   c
            943-1163            JAXUCZ010000010.1  85443694-85443914   c
            1164-1688           JAXUCZ010000010.1  85442988-85443512   c
FEATURES             Location/Qualifiers
     source          1..1688
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1688
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /note="keratin 33A"
                     /db_xref="GeneID:303527"
                     /db_xref="RGD:1306249"
     exon            1..414
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1281
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /note="type I hair keratin KA27"
                     /codon_start=1
                     /product="keratin, type I cuticular Ha3-I"
                     /protein_id="NP_001008757.1"
                     /db_xref="GeneID:303527"
                     /db_xref="RGD:1306249"
                     /translation="MPYNCCLPALSCRTSCSSRPCVPPSCHGCTLPGACNIPANVGNC
                     NWFCEGSFNGNEKETMQFLNDRLASYLEKVRQLERENAELESRIQERSQQQDPLVCPA
                     YQAYFRTIEELQQKILCGKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDIN
                     GLRRILDELTLCKSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPT
                     VDLNRVLNETRCQYEALVETNRREVEEWFTTQTEELNKQVVSSSEQLQSCQAEIIELR
                     RTVNALEIELQAQHNLRNSLENTLTESEARYSSQLSQVQCLITNVESQLGEIRADLER
                     QNQEYQVLLDIRARLECEINTYRGLLESEDCNLPCNPCATTNACDKPIGPCVSNPCVT
                     RPRCGPCNTFVR"
     exon            415..497
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
     exon            498..654
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
     exon            655..816
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
     exon            817..942
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1163
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1688
                     /gene="Krt33a"
                     /gene_synonym="Ka27; RGD1306249"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagctctga ggcttggagg attcactctg tgacttcaga ccggcacttc aaattcctcc
       61 aacaccatgc catacaactg ctgcctgccc gccctgagct gccgcaccag ctgctcctcc
      121 aggccctgcg tgccccccag ctgccatggc tgcaccctgc ccggggcttg caacatcccc
      181 gccaatgtgg gcaactgcaa ttggttctgt gagggctcct tcaatggcaa tgagaaggag
      241 accatgcagt tcctgaatga ccgcctggcc tcctacctgg agaaggtgag gcagctggag
      301 agagagaatg cagagctgga aagcaggatc caggagagga gccagcagca ggaccccctg
      361 gtgtgccccg cctaccaggc ctacttcagg accattgagg agctgcagca gaagatcttg
      421 tgtggcaaat ctgagaacgc caggctggtt gtgcagatcg acaatgccaa gctggcctct
      481 gatgacttca ggaccaagta tgagacagag ctcagtctga ggcagctggt ggagtcagac
      541 attaacggcc tgcgcaggat cctggatgag ctgaccctct gcaagtctga cctggaggct
      601 caggtggagt ccctgaagga ggagctgctg tgtctcaagc agaaccacga acaggaagtc
      661 aacaccctgc gctgccagct tggagaccgc ctcaacgtcg aggtggacgc tgctcccact
      721 gtggacctga accgtgtgct caatgagacc aggtgtcagt acgaggccct ggtggaaacc
      781 aaccgccggg aagtggagga atggttcacc acacagactg aggagctgaa caagcaggtg
      841 gtgtccagct cagagcagct gcagtcctgc caggccgaga tcattgagct gagacgcaca
      901 gtcaatgccc tggagatcga gctgcaggcc cagcacaacc tgagaaactc tctggagaac
      961 accctgacag agagtgaggc tcgctacagc tcccagctat cccaggtgca gtgcctgatc
     1021 accaacgtgg agtcccagct tggtgagatc cgggctgacc tggagcgtca gaaccaggag
     1081 taccaggtgc tgctggacat ccgggcccgg ctggagtgtg agatcaacac gtacaggggc
     1141 ctgctggaga gcgaggactg caatctcccc tgcaatccct gtgccacaac caatgcatgt
     1201 gataagccca tcgggccctg tgtctctaac ccttgtgtca caagacctcg gtgtggacct
     1261 tgcaacactt tcgtgcggta aagataccat cgccagaagg gggacaaaga tatgagttgc
     1321 accttaactc cacctcatct caagacctta aaaagtgacc acactggaca aagacagacc
     1381 ggttcttagg gtcagttcca gtccatgatg tattttctgg tttgaggaaa tgcaaagtct
     1441 gtctttggag gaatctacgg tagggtcgag taccatctac tcacacaaag ccatatttac
     1501 atactcaatg tttcgcttta ctaaaacacc tgactgtgat ttgtaaataa ttccattgag
     1561 tgtgggggat ctggctggca tgcttttgaa gcagaacatg agtgggtgta accttttttt
     1621 gttacacttt ttgtctttta aagacaatac aaatcctttg tcttcccaat aaattcttat
     1681 tctggctt
//
