LOCUS       NM_001008824            1350 bp    mRNA    linear   ROD 05-DEC-2024
DEFINITION  Rattus norvegicus keratin 27 (Krt27), mRNA.
ACCESSION   NM_001008824 XM_579221
VERSION     NM_001008824.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Tanaka,S., Miura,I., Yoshiki,A., Kato,Y., Yokoyama,H., Shinogi,A.,
            Masuya,H., Wakana,S., Tamura,M. and Shiroishi,T.
  TITLE     Mutations in the helix termination motif of mouse type I IRS
            keratin genes impair the assembly of keratin intermediate filament
  JOURNAL   Genomics 90 (6), 703-711 (2007)
   PUBMED   17920809
REFERENCE   2  (bases 1 to 1350)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BK004030.1.
            
            On Apr 19, 2005 this sequence version replaced XM_579221.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK004030.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1350
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /note="keratin 27"
                     /db_xref="GeneID:450229"
                     /db_xref="RGD:1359115"
     CDS             1..1350
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /note="K27; CK-27; cytokeratin-27; type I inner root
                     sheath-specific keratin-K25irs3; type I keratin KA40;
                     keratin 27, type I"
                     /codon_start=1
                     /product="keratin, type I cytoskeletal 27"
                     /protein_id="NP_001008824.1"
                     /db_xref="GeneID:450229"
                     /db_xref="RGD:1359115"
                     /translation="MSVRFSSASRRLGSVRLSSPGAALGAGNTCGVPGIGSGFSCAFG
                     GSSLAGGLGMGGASCGAFTVNEHGLLSGNEKVTMQNLNDRLASYLENVQALEEANADL
                     EQKIKDWYEKFGPGSCRGLDHDYSRYFPIIDDLRTQIISATAQNANIVLQNDNARLTA
                     DDFRMKYENELALHQSVDADINGLRRVLDELTLCRTDLEVQLETLSEELAYLKKNHEE
                     EMQALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFQEKSASL
                     QQQISDDAGATTSARNELTEMKRTLQTLEIELQSLLAMKHSLECSLTETEGNYCTQLA
                     QIQAQISALEEQLHQVRTETEGQKLEYEQLLNVKAHLEKEIETYCLLIGGDEGSCVKS
                     KGQGGPGNQTKDSPKTAIVKTVVEELDPRGKVLSSRVHTLEEKSTKVNNKNEQRIPS"
     exon            1..414
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            415..497
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            498..654
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            655..816
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            817..942
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1160
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1210
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1350
                     /gene="Krt27"
                     /gene_synonym="Ka40"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtctgttc gtttttcctc cgcatccaga cgcctgggct ctgtgaggct ctccagcccg
       61 ggagcagcct tgggggctgg aaatacctgc ggagtgccag gcatcggaag tggcttctcc
      121 tgcgcctttg ggggcagctc attggcaggg ggtctcggca tgggcggtgc ttcctgtggg
      181 gccttcactg tgaatgagca tggcctcctt tccggcaatg agaaggtaac catgcagaac
      241 ctcaatgacc gcctggcttc ctacctggag aatgtacaag cactagagga ggccaacgct
      301 gacctggagc agaagatcaa ggactggtat gaaaaatttg gacctgggtc gtgccgcggt
      361 cttgatcatg actacagtag atacttcccc atcattgatg acctcaggac ccagataatc
      421 tctgcaactg cacaaaacgc caacatcgtc ctgcaaaatg acaacgcgag actgacggcg
      481 gacgacttca gaatgaagta cgagaacgaa ctggcgctcc accagagcgt cgatgcggac
      541 atcaatggct tgcggagggt cctggatgag ctgaccctgt gcagaaccga ccttgaggtc
      601 cagctggaaa cactcagtga ggagctggct tatctcaaga agaaccatga ggaggaaatg
      661 caggctctgc agtgcgcggc cggaggtaac gtgaatgtgg agatgaacgc agcccccggc
      721 gtggacctca ccgtcttgct gaacaacatg cgagccgagt acgaggccct ggctgagcag
      781 aaccgcaggg acgccgaggc ctggttccaa gagaagagcg cttccctgca gcagcagatt
      841 tcagacgatg ctggagccac cacctcagcc aggaacgaac tcactgagat gaaacggact
      901 ctccaaaccc tggagataga gctgcagtcc ctcttagcca tgaaacactc tctggagtgc
      961 tccctgacgg agaccgaggg caactactgc acgcagctgg ctcagatcca ggctcagatc
     1021 agcgccctgg aggagcagct gcaccaggtg aggacggaga ccgagggcca gaagctggaa
     1081 tatgagcagc tgctgaacgt caaggcccac ctggagaagg agatcgagac ctactgcctc
     1141 ctcataggag gagacgaggg ctcttgtgtt aagtcaaaag gccaaggagg acccggaaat
     1201 cagacaaagg attcacctaa aactgccatt gttaaaactg tcgtcgaaga attagatccc
     1261 cgtggcaagg ttctgtcctc ccgagtccac accctggaag agaaatccac caaagtcaac
     1321 aacaagaacg agcagaggat cccttcttga
//
