LOCUS       NM_001398856            3165 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus keratin 222 (Krt222), mRNA.
ACCESSION   NM_001398856 XM_003750923
VERSION     NM_001398856.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3165)
  AUTHORS   Hesse M, Zimek A, Weber K and Magin TM.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000220.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001398856.2.
            
            On Dec 27, 2021 this sequence version replaced XM_003750923.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK004026.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-166               JACYVU010000220.1  41020673-41020838   c
            167-295             JACYVU010000220.1  41016431-41016559   c
            296-516             JACYVU010000220.1  41014541-41014761   c
            517-593             JACYVU010000220.1  41012581-41012657   c
            594-729             JACYVU010000220.1  41012255-41012390   c
            730-3165            JACYVU010000220.1  41008995-41011430   c
FEATURES             Location/Qualifiers
     source          1..3165
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..3165
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /note="keratin 222"
                     /db_xref="GeneID:497994"
                     /db_xref="RGD:1560383"
     exon            1..166
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..958
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /note="keratin 222, type II"
                     /codon_start=1
                     /product="keratin-like protein KRT222"
                     /protein_id="NP_001385785.1"
                     /db_xref="GeneID:497994"
                     /db_xref="RGD:1560383"
                     /translation="MELSQLLNEIRANYEQLLTRNQIDTVLSTRIQLEEDLTKKMDKD
                     GEALKAAQAELKEARRQCHHLQVEIESLHAVERGLENSLQASEQHYQMQLQDLESVIG
                     RLEKELQEVRRGIERQLQEHEMLLNTKMRLEQEIATYRRLLEQEEIRYYGCIQGERKE
                     DKPAKSKVGFLLPSAIINEISFSTKVSHKYENESVETVTKQAVVNGDVAKESAEAHGT
                     IQTEKVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLESRQDNLPDIEVR
                     LIMRRSCSIPSIKPPPGTN"
     exon            167..295
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /inference="alignment:Splign:2.1.0"
     exon            296..516
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /inference="alignment:Splign:2.1.0"
     exon            517..593
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /inference="alignment:Splign:2.1.0"
     exon            594..729
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /inference="alignment:Splign:2.1.0"
     exon            730..3165
                     /gene="Krt222"
                     /gene_synonym="Ka21p; RGD1560383"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcaggctct gccgcagcga ctcatcccat cgctaaggtc cagttagcca aggtggagga
       61 tgggaaaaga atggagctgt cccagctcct caatgagatc agggcaaact atgagcagct
      121 cctcaccaga aatcagatag acacggtgct gtcaacacgg atccagctgg aggaagattt
      181 aaccaaaaaa atggacaagg atggagaggc tctgaaggct gctcaggctg aactcaagga
      241 ggctcgccgg cagtgccacc acctgcaagt ggaaatcgag tctctccatg ctgtggaaag
      301 gggccttgaa aactccctgc aggccagtga gcagcattat cagatgcagc tgcaagatct
      361 ggagtcggtg attggccgac tggagaagga gctgcaggaa gtgaggcgtg gcatcgagag
      421 gcagcttcaa gagcacgaga tgcttctcaa cacgaagatg aggctggagc aggaaatagc
      481 cacgtaccgc cgcctgctag aacaggaaga gatcaggtat tacggttgta tccaaggaga
      541 gagaaaagaa gacaagcccg ccaaaagtaa agttggcttt cttctcccct cagccattat
      601 aaatgaaata tctttttcga caaaagtctc acataagtat gaaaatgaaa gtgtggagac
      661 agtgaccaaa caggcagtgg tgaatggaga cgtggcgaag gagagtgcgg aggcccacgg
      721 caccattcag acagagaaag tggatgaagt tataaaagaa tgggaaggtt cgttctttaa
      781 ggataaccct cgactgagga aaaagtctgt ttccctccgg ttcgatctcc acttggcagc
      841 cacggatgag ggctgtttag agagtagaca agataatttg ccagatatcg aagtcaggct
      901 tatcatgaga aggtcctgta gtattccctc catcaaaccc ccaccaggaa ccaactaacc
      961 cagagatcgt atttatcaag gacagtagga tggacctaag taggccgtac agacccccca
     1021 gtcccaaatg taagttattt tatatgtacg gagagtgaga ggatgctgtg ggctgtggct
     1081 ctcttcagaa aacacataag aaagaggaac tttgctaaga ctccaaagag gagctttttt
     1141 tttttttttt tttttttttt ttgagcaggg ttgcttaaaa ataaatcaga aatccagtgt
     1201 ggtttctgtt ttatttgtca tctaaatagt ctttattctg gcaagcttta tcagagactt
     1261 taagtattaa ggtggcctca tcaagtctgt aattttcctc aaaggctgaa catccaaagg
     1321 aaaatagaat agcttgtttg aagcctgaag agctacaatg agtttctctc cgtggttcca
     1381 ggaccagttg aacctaaaat gttctacttc taagaaggca gcagttaggg acaaacgttg
     1441 aaggaggggg gctcgatatt cacttaggac ttctgctttt gagacaatca ttggaaccct
     1501 gggaattatg aagtgttctg cccaggagca attctgagtg aagtgcaaag catgccccca
     1561 ggctattttg ctgattaata aaatttggtt actctatatc ttaaaacttt ttaaaaatca
     1621 gtatgagaag agtcagtttg ttgaaagata cagattgtgt acacacacac acacacacac
     1681 acacacacac acacacacac acacattcca gctatacaga ccttttaaaa gcacattgaa
     1741 aaggtggtga ctccagttag taggacagtt tctcaacagc tcacttctgc tcttccagtt
     1801 gtaaaatgaa gtgtgagtag catttactat gggcctcaga ggagagattc tgtgaacttg
     1861 gaaaaatggt tcttgcagtc atttctgtga actcacagca tatcattgct ctctgagcta
     1921 agagtgtctg caggacttgt ttttaaattg ttcaaactat aacaaataga gaagtaaaaa
     1981 tatttgtgaa taagtgaatt gttgcaaggg tttttcctgt tgtttttttt aatttattta
     2041 tttatttatt tactatatgt atatttctgc aaaccagaag agggcattgg atcccattac
     2101 agatggttgt gagccaccat gtggttgctg ggaattgaac tcaggacctc cggaagagcg
     2161 gccagtgctc ttaacccctg agccatctct ccagccctgt tgcaaaattt ttttaaaaac
     2221 ctaaatttaa tgcgggtaca tttactttga gaccttaagt aataaatacc tgtcttacga
     2281 cattagacat ttctaggctt tttttcctaa actacaaaaa gggaacccaa accattcgcc
     2341 actgttcttc gtttgcagct gaagtatcat ctaagggcta cagctatact agcattttag
     2401 tggggccttc aaaacccatt cccctctcct cctccctctc tctccacgtg tgtgtatata
     2461 tgcatatatg ttgactagta aatgtgcttt agccacaagg aacttaggtt aacttacttc
     2521 agtataatcc aggggtttaa cgttcgtctt ttccattact ctaggtttct ttcagcctga
     2581 ctcagtctgg ttagtaaaag aggaatgatg ttgtttgtca aagtcacaac ggcatcactt
     2641 ctcggcctct tggctaagat caagtgtaaa gtcacaacgg catattaagg gcttgttctt
     2701 gaataagcat ctgacctaaa attgtatcct ctacataaaa ttgtttcttc agggctgggg
     2761 tatggcaggg tgcaaagcta cacatagctc acaggaggta ctgggtttgg acctcaggga
     2821 ataaaaagtg gggggagggg gagtttcatt catcattaag tgcttcaact ttattaaagc
     2881 tttgactgca gtcatatgag ctgttgtgct ggctactgta ttatgcaacc acggttataa
     2941 tatggcgata catttagtgc agtcacccgc cacgttagtg ctgggccttg tatatcaacc
     3001 gcttgctaga gaaatccccc tgtgccgcag ttatgtgtgt aacatgcagt acttgaattc
     3061 ctaaatgagt ttgcttctgt ttgctttgag gcattttaaa aatcagaata tgagtttacc
     3121 aaagtaaatg ataccaccat aataaaaaaa aaaattaaac atgaa
//
