LOCUS       NM_001004021            1619 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus keratin 13 (Krt13), mRNA.
ACCESSION   NM_001004021 XM_213479
VERSION     NM_001004021.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Li,Y., Zhang,Y., Qiu,F. and Qiu,Z.
  TITLE     Proteomic identification of exosomal LRG1: a potential urinary
            biomarker for detecting NSCLC
  JOURNAL   Electrophoresis 32 (15), 1976-1983 (2011)
   PUBMED   21557262
REFERENCE   2  (bases 1 to 1619)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1619)
  AUTHORS   Sakamoto,K., Aragaki,T., Morita,K., Kawachi,H., Kayamori,K.,
            Nakanishi,S., Omura,K., Miki,Y., Okada,N., Katsube,K., Takizawa,T.
            and Yamaguchi,A.
  TITLE     Down-regulation of keratin 4 and keratin 13 expression in oral
            squamous cell carcinoma and epithelial dysplasia: a clue for
            histopathogenesis
  JOURNAL   Histopathology 58 (4), 531-542 (2011)
   PUBMED   21371075
REFERENCE   4  (bases 1 to 1619)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   5  (bases 1 to 1619)
  AUTHORS   Aoyagi,H., Asami,T., Yoshizawa,H., Wanichanon,C. and Iwasaki,S.
  TITLE     Newly developed technique for dual localization of keratins 13 and
            14 by fluorescence immunohistochemistry
  JOURNAL   Acta Histochem 110 (4), 324-332 (2008)
   PUBMED   18262229
  REMARK    GeneRIF: K13 immunoreactivity was generally evident in the
            suprabasal cells of the interpapillary cell columns and K14
            immunoreactivity was detected in the basal and suprabasal cells of
            the papillary and interpapillary cell columns
REFERENCE   6  (bases 1 to 1619)
  AUTHORS   Iwasaki,S., Yoshizawa,H. and Aoyagi,H.
  TITLE     Immunohistochemical expression of keratins 13 and 14 in the lingual
            epithelium of rats during the morphogenesis of filiform papillae
  JOURNAL   Arch Oral Biol 51 (5), 416-426 (2006)
   PUBMED   16271699
REFERENCE   7  (bases 1 to 1619)
  AUTHORS   Hesse,M., Zimek,A., Weber,K. and Magin,T.M.
  TITLE     Comprehensive analysis of keratin gene clusters in humans and
            rodents
  JOURNAL   Eur J Cell Biol 83 (1), 19-26 (2004)
   PUBMED   15085952
REFERENCE   8  (bases 1 to 1619)
  AUTHORS   Waseem,A., Alam,Y., Dogan,B., White,K.N., Leigh,I.M. and
            Waseem,N.H.
  TITLE     Isolation, sequence and expression of the gene encoding human
            keratin 13
  JOURNAL   Gene 215 (2), 269-279 (1998)
   PUBMED   9714826
  REMARK    Erratum:[Gene 1998 Oct 23;221(2):287]
REFERENCE   9  (bases 1 to 1619)
  AUTHORS   Richard,G., De Laurenzi,V., Didona,B., Bale,S.J. and Compton,J.G.
  TITLE     Keratin 13 point mutation underlies the hereditary mucosal
            epithelial disorder white sponge nevus
  JOURNAL   Nat Genet 11 (4), 453-455 (1995)
   PUBMED   7493031
REFERENCE   10 (bases 1 to 1619)
  AUTHORS   Denning,M.F. and Verma,A.K.
  TITLE     The mechanism of the inhibition of squamous differentiation of rat
            tracheal 2C5 cells by retinoic acid
  JOURNAL   Carcinogenesis 15 (3), 503-507 (1994)
   PUBMED   7509732
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jun 3, 2021 this sequence version replaced NM_001004021.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK004044.1, SRR22582416.491059.1
                                           [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN11044071
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-538               JAXUCZ010000010.1  85555962-85556499   c
            539-621             JAXUCZ010000010.1  85554856-85554938   c
            622-778             JAXUCZ010000010.1  85554538-85554694   c
            779-940             JAXUCZ010000010.1  85554199-85554360   c
            941-1066            JAXUCZ010000010.1  85553965-85554090   c
            1067-1287           JAXUCZ010000010.1  85553651-85553871   c
            1288-1310           JAXUCZ010000010.1  85552894-85552916   c
            1311-1619           JAXUCZ010000010.1  85552287-85552595   c
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1619
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /note="keratin 13"
                     /db_xref="GeneID:287699"
                     /db_xref="RGD:1302937"
     exon            1..538
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1384
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /note="K13; CK-13; cytokeratin-13; type I keratin KA13;
                     keratin 13, type I"
                     /codon_start=1
                     /product="keratin, type I cytoskeletal 13"
                     /protein_id="NP_001004021.1"
                     /db_xref="GeneID:287699"
                     /db_xref="RGD:1302937"
                     /translation="MSCRFQSSSMSYGGGFGAGSCQLGGGRNISTCSSRFVTGGSSGG
                     YGGGMSCGFGGGAGGGYGGGFGGGFGGSCGGGFGGGFGDFGSVDGGLLSGNEKITMQN
                     LNDRLASYLEKVRALEAANADLEVKIRDWHLKQSPTSPERDYSAYYKTIEELRIKILE
                     ATTDNNRIVLEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLAKTDLE
                     MQIESLNEELAYLKKNHEEEMKEFSNQAVGQVNVEMDATPGIDLTRVLAEMREQYEAL
                     AEKNRRDAEAWFQAKSAELNKEVSSNAAMIQTSKTEITELRRTLQGLEIELQSQLSMK
                     AGLESTLAETECRYALQLQQIQALISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ
                     EIATYRSLLEGQDAKMTGFNTGGNSTTTSNTSTSPSTSGRPDFRKY"
     exon            539..621
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     exon            622..778
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     exon            779..940
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1066
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1287
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1310
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1619
                     /gene="Krt13"
                     /gene_synonym="Ka13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atagtcctct cttggccttg gtcaagttca gctcctgtct gctctctctc accctcttgc
       61 tcccaccatg agctgtcgct ttcagagttc ctccatgagc tatggaggtg gttttggggc
      121 tggttcttgc cagcttggag gaggccggaa tatctctacc tgttcttctc ggtttgtcac
      181 tggaggatca tctggaggct acggaggtgg catgagctgt ggctttggtg gaggggctgg
      241 tggtggttat ggaggtggct ttggaggtgg ctttggaggt agctgtggcg ggggttttgg
      301 cggtggcttt ggtgactttg gaagtgtcga cggtggcctc ctctctggca atgagaagat
      361 taccatgcag aacctcaatg accgcctggc cagctacctg gaaaaggtgc gcgccttgga
      421 ggcagccaat gccgacttgg aggtgaagat tcgtgactgg catctgaagc agagcccaac
      481 cagtccagag cgggactaca gtgcttacta taagaccata gaggagctcc ggatcaagat
      541 tctggaagcc accaccgaca acaaccggat cgtcctggag atcgacaatg ccaggctggc
      601 tgcagatgac ttcaggctca agtatgaaaa cgagctggcc ttgcgccaga gcgtggaggc
      661 ggacatcaac ggtctgcgca gggtgctgga cgagctgacc ctggctaaga ctgacctgga
      721 gatgcagatt gagagcttga atgaagaact ggcttacctg aagaagaacc acgaagagga
      781 gatgaaggaa ttcagcaacc aggcagtagg ccaagtcaat gtggagatgg acgccacccc
      841 tggcattgat ctgacccgtg tgctggctga gatgagggaa cagtatgaag ccctggcaga
      901 gaagaatcgg agggatgccg aggcatggtt ccaggccaag agtgcagaac tgaacaagga
      961 agtatcctcc aatgctgcca tgattcagac cagcaagaca gagatcacag agctccggcg
     1021 cacactccag ggtctggaga ttgagctgca atcccagctg agcatgaaag ccggcctgga
     1081 aagtaccttg gcagagacgg agtgccgcta cgccctgcag ctgcaacaga tccaggctct
     1141 catcagcagc atcgaggccc agctgagcga gctccgcagc gagatggagt gccagaacca
     1201 ggaatacaag atgctgctgg acatcaaaac acggctggag caggagatcg ccacctaccg
     1261 cagcctgcta gagggccagg atgctaagat gactggcttc aacactggag gaaatagcac
     1321 taccacctcc aacacatcca cctccccctc cacttctggt cgcccggatt tccgaaagta
     1381 ttaactcagc ctggcgtccc ttccctggcc ttcaggagga gagctgatgg cacctgtagg
     1441 atgagaggac tgaaggatgt gaagcccagt cctcttgtcc cccctgaggg tggaccctcc
     1501 cccatctctc ttgattggaa tcctcttcct ccctaccctg ttctttctat tctttggttt
     1561 ctcaatgtct ctactacaaa gaatagatga ttcaataaag tttcttgatt ttctgcaaa
//
