LOCUS       NM_001002290            2815 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus keratinocyte proline-rich protein (Kprp), mRNA.
ACCESSION   NM_001002290 XM_579077
VERSION     NM_001002290.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2815)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   2  (bases 1 to 2815)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 2815)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2815)
  AUTHORS   Kong,W., Longaker,M.T. and Lorenz,H.P.
  TITLE     Molecular cloning and expression of keratinocyte proline-rich
            protein, a novel squamous epithelial marker isolated during skin
            development
  JOURNAL   J Biol Chem 278 (25), 22781-22786 (2003)
   PUBMED   12668678
  REMARK    GeneRIF: Kprp (keratinocyte proline-rich protein) is expressed by
            fetal dermal keratinocytes during late gestation and is a new
            marker of maturing epidermis during fetal skin development.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF548002.1.
            
            On Apr 19, 2005 this sequence version replaced XM_579077.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF548002.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN09345330, SAMN16093042
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2815
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2815
                     /gene="Kprp"
                     /note="keratinocyte proline-rich protein"
                     /db_xref="GeneID:432393"
                     /db_xref="RGD:1303244"
     exon            1..14
                     /gene="Kprp"
                     /inference="alignment:Splign:2.1.0"
     exon            15..2815
                     /gene="Kprp"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..2142
                     /gene="Kprp"
                     /note="keratinocytes proline-rich protein"
                     /codon_start=1
                     /product="keratinocyte proline-rich protein"
                     /protein_id="NP_001002290.1"
                     /db_xref="GeneID:432393"
                     /db_xref="RGD:1303244"
                     /translation="MCDQQEIQCCGPIPQCCVKGSSFGPSQFPYANNQVLVEAPCEMQ
                     FLECAAPCPIQVSQTPCQSSTTEVKGQAPCKTTNVKCQTKTTQVKCQPKTTEIKCQAP
                     CQAQVSCVQCQAPCQSQVSYVQVPQPPQTYYVECAPVYYTETRFVEYPVSNYVPVPAP
                     QPGYTYVECPSLGQGQGQGSFSTRYQYQGSYGSCTSQSQSRGSYSSCGPQHQSQASYS
                     YCEPQFQSRPSYTNCGTQRQSQASFGSCTSQLQSRASYSNCSSQRRSGTSFSTCAPQC
                     QGQGTYGSFTAQRKSQSASRCLPSRRLQPSYRSCSPPRHSEPCYSSCLPSRCSSGSYN
                     YCTPPRRSEPIYGSHCSPRGRPSGCSQRCGPKCRIEISSPCCPRQVPPQRCPVQIPPI
                     RGRSRSCPRQPSWGVSCPDLRPCAEPHAFPRPCRPQRLDRSPESSWRRCPVPAPRPYP
                     RPEPCPSPEPRPCPRPRPRPEPCPSPEPRPRPRPDPCPSPELRPRPRPEPCPSPEPRP
                     RPRPDPCPSPEPRPRPCPEPCPSPEPRPCPPLRRFSEPCLYPEPCSVSKPVPCPVPCP
                     APHPRPVHCETPGRRPQPSPRSQPCPHPEPMPRPVPCSSPVPCGDPIHCPSPCSGHNP
                     VPYSQELGCHESNPCRLDTEGPSSYSFSQGQESNGCCVSGGVFSGSRGLSGCGDQGNT
                     YRGMNCGACGGTQGAYF"
ORIGIN      
        1 gcctgctgag gagggtcttg ctcacccacc tgcaccagga ccatgtgtga ccagcaagag
       61 attcagtgtt gtgggccaat accccagtgc tgtgtcaagg gttcctcctt tggtccctca
      121 cagtttcctt atgccaacaa ccaggtgcta gtggaagctc cgtgtgagat gcaatttctg
      181 gaatgtgctg caccatgccc cattcaagtt tctcagactc catgccagtc cagtaccact
      241 gaagtgaagg gccaggctcc atgtaaaacc accaacgtta aatgccagac caagaccacc
      301 caggtgaaat gccagcctaa gaccactgag ataaagtgcc aggctccctg ccaggctcag
      361 gtttcctgtg ttcaatgcca ggctccatgc caatctcagg tttcctatgt gcaagttcca
      421 caacctcctc agacctacta tgtagagtgt gctccagtgt attatacaga aactcgtttt
      481 gtggaatatc cagtttcaaa ctacgtgcct gttccagctc ctcagcctgg gtacacttat
      541 gtagaatgtc cctcactggg ccagggccag ggccagggaa gtttctccac tcggtaccag
      601 tatcagggat cctatggtag ctgcacttct caatcacagt cacggggttc ttacagcagc
      661 tgtggtccac agcatcagtc tcaggcttcc tacagttact gcgaacccca gtttcagtcc
      721 agaccctcct ataccaactg tggtactcag cgccagtcac aggcttcctt tggcagctgc
      781 acctcccaac tccagtctcg agcatcctac agcaactgct cctcccagcg tcggtccggg
      841 acttccttta gcacttgtgc acctcaatgc cagggccagg gcacctatgg aagctttact
      901 gcacagcgca agtctcagag tgccagccga tgcctccctt ctcgtcggct tcagccttct
      961 tatcgcagct gctctccacc aagacattct gagccctgtt atagcagctg cctgccatcc
     1021 cggtgctctt caggctccta caactattgc actccacccc gccgctcaga acccatctac
     1081 ggcagccact gttctcctcg gggccgccct tcaggctgtt ctcaaagatg tggacccaaa
     1141 tgcaggatag agatttcctc gccttgctgc ccaaggcagg ttccccctca gaggtgtcct
     1201 gtccagattc ctcccatcag aggaagatct cggagttgtc cccggcaacc ttcttggggt
     1261 gtctcttgcc cagacctgag gccatgcgca gaaccacatg cattcccaag accttgtagg
     1321 ccacagcgtc ttgaccggtc tccagaatca tcatggcggc ggtgtccagt tcctgcacca
     1381 cgtccatatc cacgtccaga accatgccca agtccagaac cacgtccatg cccacgccca
     1441 cgcccacgtc cagagccatg cccaagtcca gaaccacgcc cacgcccacg tccagaccca
     1501 tgcccaagtc cagaactacg cccacgccca cgtccagagc catgcccaag tccagaacca
     1561 cgcccacgtc cacgtccaga cccatgccca agtccagagc cccgcccacg tccatgtcca
     1621 gagccatgcc caagtccaga acctcgccca tgtcctccat tgaggcgatt ttcagaaccc
     1681 tgtctgtatc cagaaccatg ttcagtttct aagccagtgc catgtccagt accatgccca
     1741 gcgccacatc cacgcccagt tcactgtgag actccaggtc gacgtccaca acccagtcct
     1801 cgttcacaac cttgtccgca tccagaacca atgccacgtc cagtgccctg ctccagtcca
     1861 gtgccttgtg gagatcccat tcattgtccc agtccttgct caggtcacaa tccagttcct
     1921 tacagccaag aactaggctg tcatgaatct aacccatgtc gcctggatac tgaaggcccg
     1981 agctcctata gcttcagcca agggcaagag agtaatggct gctgtgtatc tggtggtgtc
     2041 ttttcaggat cacgcggttt aagtggttgt ggagatcaag gaaacaccta tcgtggcatg
     2101 aattgtgggg cttgtggtgg aacacaggga gcctactttt aaacaaaagt ataacccaaa
     2161 tgctcctgcg ttaggttctt tagagtattt ccccttctta tctggtttaa tctttccata
     2221 gacattgagg tgcttcctgc ttccaagttg ttatccaaac ttcttgcatg ttacctcacg
     2281 ttctacacct gaatccctga catcattcca gccttatgtc tcaatccttc tttgcacaga
     2341 gctttaattc taactagacc agcttggtca ctaggacact ccttgggtgt ttctcctgac
     2401 agtccccaga tgctcttgcc tctgcagagg cttcctcagt ctgaaccact tctcactatt
     2461 tcccaggatc taaaattgta cctgtctttc aataactcct cctgaatctt ttactgttgt
     2521 tgtgtgtttc tacccatagg accctattct gacttcctag aattcactgc tctaatacca
     2581 ttcatttagt aagtgctttt caatactctt gaattagtaa tttctcctgc cttttctgcc
     2641 taactagatt gcaaactttc atccaagtgg aattagtata tccttgtgtc tatcttaggt
     2701 caggtaataa ttgaacaagg ttatggttgg cagcttgaga atgctctgtc ctgttgggaa
     2761 agtacaggaa ctgtgacaat aggaagatac ataacaataa aaactggatg tattc
//
