LOCUS       NM_001015029            2181 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus karyopherin subunit alpha 6 (Kpna6), mRNA.
ACCESSION   NM_001015029 XM_342926
VERSION     NM_001015029.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2181)
  AUTHORS   Bertram S, Thiele S, Dreier C, Resa-Infante P, Preuss A, van Riel
            D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD and Gabriel G.
  TITLE     H7N9 Influenza A Virus Exhibits Importin-alpha7-Mediated
            Replication in the Mammalian Respiratory Tract
  JOURNAL   Am J Pathol 187 (4), 831-840 (2017)
   PUBMED   28189564
REFERENCE   2  (bases 1 to 2181)
  AUTHORS   Rother F, Shmidt T, Popova E, Krivokharchenko A, Hugel S,
            Vilianovich L, Ridders M, Tenner K, Alenina N, Kohler M, Hartmann E
            and Bader M.
  TITLE     Importin alpha7 is essential for zygotic genome activation and
            early mouse development
  JOURNAL   PLoS One 6 (3), e18310 (2011)
   PUBMED   21479251
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2181)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2181)
  AUTHORS   Plant KE, Everett DM, Gordon Gibson G, Lyon J and Plant NJ.
  TITLE     Transcriptomic and phylogenetic analysis of Kpna genes: a family of
            nuclear import factors modulated in xenobiotic-mediated liver
            growth
  JOURNAL   Pharmacogenet Genomics 16 (9), 647-658 (2006)
   PUBMED   16906019
REFERENCE   5  (bases 1 to 2181)
  AUTHORS   Sakakida Y, Miyamoto Y, Nagoshi E, Akashi M, Nakamura TJ, Mamine T,
            Kasahara M, Minami Y, Yoneda Y and Takumi T.
  TITLE     Importin alpha/beta mediates nuclear transport of a mammalian
            circadian clock component, mCRY2, together with mPER2, through a
            bipartite nuclear localization signal
  JOURNAL   J Biol Chem 280 (14), 13272-13278 (2005)
   PUBMED   15689618
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC105813.1.
            
            On Oct 19, 2005 this sequence version replaced NM_001015029.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105813.1, AY779030.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2181
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2181
                     /gene="Kpna6"
                     /note="karyopherin subunit alpha 6"
                     /db_xref="GeneID:362607"
                     /db_xref="RGD:1306570"
     exon            1..47
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1654
                     /gene="Kpna6"
                     /note="karyopherin (importin) alpha 6; karyopherin alpha 6
                     (importin alpha 7); karyopherin (importin) alpha 6-like"
                     /codon_start=1
                     /product="importin subunit alpha-7"
                     /protein_id="NP_001015029.2"
                     /db_xref="GeneID:362607"
                     /db_xref="RGD:1306570"
                     /translation="MKNYVSETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLR
                     KQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQ
                     LATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRSENCTLQFEAAWALTNIASG
                     TSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNP
                     LLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLAD
                     ACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQT
                     QVILNCSALPCLLHLLSSSKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEIL
                     QKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGL
                     ENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFG
                     VEDDDSSLAPQVDETQQQFIFQQPEAPMEGFQL"
     exon            48..181
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            182..274
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            275..374
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            375..469
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            470..601
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            602..690
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            691..790
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            791..954
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1033
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1159
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1287
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1466
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..2159
                     /gene="Kpna6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcctctgg gacagcacag gctcaatcat gaaaaactat gtgtcagaga ccatggcaag
       61 cccagggaaa gacaattatc gaatgaagag ctataagaac aatgccttaa accctgagga
      121 aatgagacga agaagggagg aagagggcat tcagcttcgg aaacagaagc gggagcagca
      181 actttttaaa cggagaaatg tggagctgat taatgaagaa gctgccatgt ttgacagtct
      241 gctgatggat tcctacgtga gctccacaac tggggagagt gtgatcacaa gggaaatggt
      301 ggagatgctc ttttctgacg attctgactt acagttagca accacacaga aattccggaa
      361 actcctttcc aaagagccaa gtcctccaat agatgaagtt attaacactc caggagtagt
      421 tgatcggttt gtggagtttc tgaagaggag tgagaattgt acattacagt ttgaagctgc
      481 ctgggctcta acaaacattg cctctggaac ctctcagcag accaaaattg tcattgaagc
      541 aggagctgtc cccattttta tagagctgct taactcagac tttgaagatg tacaagaaca
      601 ggcagtctgg gctcttggaa acatagctgg agacagttca gtctgcagag actatgtctt
      661 gaattgttcc atccttaatc ctctgttaac actccttact aagtccacac gactgacgat
      721 gacacggaat gcagtctggg ccctgtcaaa cctctgccga gggaagaacc ctcctccaga
      781 gttcgcaaag gtctctcctt gtttgcctgt attgtctcgc ctactcttca gcagcgactc
      841 agacttgctg gcagatgctt gctgggccct ctcttacctg tctgatggcc ccaatgagaa
      901 gatccaggca gtcatagact ctggagtctg ccggagattg gtagagcttc tgatgcacaa
      961 cgattacaaa gtggcgtctc ctgccttgag agctgtgggt aatattgtca ccggggatga
     1021 tatccagacc caggtcattc ttaactgttc agccctccct tgcctcctcc acctgctgag
     1081 cagctctaag gaatcaatcc ggaaggaagc ttgctggacc atttcaaaca tcactgctgg
     1141 caacagggct caaatacagg ctgtcataga tgcaaatatc ttccctgtat tgatcgaaat
     1201 ccttcagaaa gcagagttcc gtacgaggaa agaagcagcc tgggccatca ccaatgcaac
     1261 ctcaggagga acccctgagc aaatcaggta cttggtatca ctgggctgca ttaagcccct
     1321 gtgtgacttg ctgactgtaa tggattcaaa aattgtacaa gtggccctca atggactaga
     1381 gaacattctg cggctcggag agcaagaggg caagcgcagt ggctcagggg tcaatcccta
     1441 ctgtggcctc atcgaggaag cctatggctt ggataagatt gagtttctcc agagccatga
     1501 gaaccaggag atctaccaga aggcctttga cctcatcgag cactactttg gtgtagagga
     1561 tgacgacagc agcctggccc ctcaggtgga cgagactcag cagcagttca tcttccagca
     1621 gcccgaggcc cccatggagg gcttccagct ataatgtccg cctccgggga gggggcaggg
     1681 cacggcatgc accagcagcc agcagaggag cagccttctg gtgggcagga gaacaggccc
     1741 caccagcccc gcacacctgc tgccctggac actgtgttcg tgacctgctc accccttccc
     1801 tggaggaggg agtgccctcg ggacagacag aaccatcaga ggctcacagt gggtttgtga
     1861 caagaagggg acgtgcgggt ctatcttcct tacactttat tttggctgca cacatgtctt
     1921 taacccagga gcccaggggt agacaaagga ggactgaggt aatcaatttg cacctttaaa
     1981 tttttttctt ttattttctt tagtggtgac ttccttccca gttatctttc ttcatccatc
     2041 ccagtcctct gccctgacat gtgtaactct tgggtacttg agcagatgga atattccaga
     2101 ggtgggaggt gggaggggag gggagaagtc cgaaacaaag tgttcttgct ctgaccgaaa
     2161 aaaaaaaaaa aaaaaaaaaa a
//
