LOCUS       NM_001025113            4922 bp    mRNA    linear   ROD 18-FEB-2024
DEFINITION  Rattus norvegicus karyopherin subunit alpha 5 (Kpna5), mRNA.
ACCESSION   NM_001025113 XM_006256442 XM_215386
VERSION     NM_001025113.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4922)
  AUTHORS   Plant,K.E., Everett,D.M., Gordon Gibson,G., Lyon,J. and Plant,N.J.
  TITLE     Transcriptomic and phylogenetic analysis of Kpna genes: a family of
            nuclear import factors modulated in xenobiotic-mediated liver
            growth
  JOURNAL   Pharmacogenet Genomics 16 (9), 647-658 (2006)
   PUBMED   16906019
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000324.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001025113.3.
            
            On or before Dec 14, 2022 this sequence version replaced
            XM_006256442.3, NM_001025113.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132268,
                              SAMD00132269 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JACYVU010000324.1  26546847-26546974
            129-262             JACYVU010000324.1  26550895-26551028
            263-364             JACYVU010000324.1  26552530-26552631
            365-464             JACYVU010000324.1  26552746-26552845
            465-559             JACYVU010000324.1  26556535-26556629
            560-691             JACYVU010000324.1  26559164-26559295
            692-780             JACYVU010000324.1  26561136-26561224
            781-880             JACYVU010000324.1  26574161-26574260
            881-1044            JACYVU010000324.1  26594734-26594897
            1045-1123           JACYVU010000324.1  26596856-26596934
            1124-1249           JACYVU010000324.1  26599062-26599187
            1250-1377           JACYVU010000324.1  26599949-26600076
            1378-1556           JACYVU010000324.1  26607564-26607742
            1557-4922           JACYVU010000324.1  26608593-26611958
FEATURES             Location/Qualifiers
     source          1..4922
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..4922
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /note="karyopherin subunit alpha 5"
                     /db_xref="GeneID:294392"
                     /db_xref="RGD:1561324"
     exon            1..128
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..1744
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /note="karyopherin alpha 5 (importin alpha 6)"
                     /codon_start=1
                     /product="importin subunit alpha-6"
                     /protein_id="NP_001020284.2"
                     /db_xref="GeneID:294392"
                     /db_xref="RGD:1561324"
                     /translation="MDSMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKRE
                     EQLFKRRNVSLPRNDDCMLESPIQDPDVSSTVPIPEEDMITADMIQMIFSNNAEQQLT
                     ATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTF
                     LHTKVVIETGAVPIFIRLLTSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLL
                     ELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVC
                     WALSYLSDGPNDKIQVVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQV
                     ILNCSALPCLLHLLGSPKESVRKEACWTISNITAGNRMQIQAVIDGSIFPVLIEVLQK
                     AEFRTRKEAAWAITNATSGGAPEQIRYLVTLGCIKPLCDLLTVMDSKIVQVALNGLEN
                     ILRLGERESKQNGVGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIERYFGVE
                     EDDPSLVPQVDEQQRQFLFQQCEAPGEGFQL"
     exon            129..262
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            263..364
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            365..464
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            465..559
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            560..691
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            692..780
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            781..880
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1044
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1123
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1249
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1377
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1556
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..4922
                     /gene="Kpna5"
                     /gene_synonym="Ipoa6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccatcttgg gttgcttagc tgctcgccgg ggacaggctg gagtcggaga gtccaccctg
       61 agctgtccgc agccgaggcc acagcgggag actataagga agggctcggg agagcaccgc
      121 gtggatggat tcaatggcta gtcctggtaa ggataactac agaatgaaaa gttacaagaa
      181 caaagcctta aatcctcaag agatgcgaag acgaagagaa gaagaaggaa tacaacttcg
      241 aaaacaaaaa agggaggagc agttgttcaa acgcagaaat gtctctttgc ccagaaatga
      301 tgactgtatg ctggagagcc ctatccagga cccagatgtc agctccactg tacccattcc
      361 agaggaagac atgatcacag cagatatgat tcagatgatt ttctctaata acgctgaaca
      421 gcaactgact gcaacacaga aatttagaaa actgctttct aaagaaccca atccaccaat
      481 agatcaagtt atacagaaac caggagttgt acagagattt gtgaagtttc ttgaaagaaa
      541 tgaaaattgc actttacaat tcgaggctgc ctgggcgtta actaatatag catctggaac
      601 ttttctgcat accaaggtag tgattgaaac cggggctgtg ccaattttta tcagacttct
      661 cacttcagaa catgaagatg tacaggaaca ggcggtttgg gcacttggta acattgctgg
      721 cgacaatgca gaatgcaggg attttgtttt gaattgtgaa atacttccac ctcttttaga
      781 gttattaaca aattcaaaca gacttacaac caccagaaat gctgtatggg ccctctcaaa
      841 tttatgtaga ggcaaaaacc ctcctccaaa ttttagtaag gtttcacctt gcttaaatgt
      901 cttatcccgg ttgttgttta gcagtgatcc agatgtgtta gcagatgtgt gctgggccct
      961 ttcttatctc tctgatggac ccaatgataa aattcaagta gtcattgatt ctggagtctg
     1021 ccgaagattg gtggaacttt tgatgcacaa tgactataaa gttgtatcac ctgcattaag
     1081 agcagttggt aatattgtaa ctggtgatga cattcaaaca caggtcattt tgaattgttc
     1141 tgcattgccc tgccttttac atttgctggg aagtccaaag gagtcagtta gaaaggaagc
     1201 ctgctggacc atttctaaca tcactgcggg aaacagaatg cagatccagg ctgtcataga
     1261 tggaagtatt ttccctgttt tgattgaggt cctccagaaa gcagaatttc gtaccagaaa
     1321 agaagcagcg tgggctataa ccaatgccac atcgggaggc gctccagagc agataaggta
     1381 tttggtaacc ttgggctgca ttaaaccact ttgtgacctt ttgactgtca tggactccaa
     1441 aatagttcaa gttgctttga atggacttga aaatatttta cgccttggag aacgagaatc
     1501 taagcagaat ggagtgggca tcaatccata ctgtgctctc attgaagaag cgtacggctt
     1561 ggataaaata gagtttctgc aaagtcatga aaaccaggaa atttaccaga aggcttttga
     1621 tctgattgaa cgctattttg gtgtggagga ggatgaccct agtctcgttc ctcaggtgga
     1681 tgagcagcag cggcagtttc tctttcagca gtgcgaggca ccaggagaag gcttccagct
     1741 ctgacatggg gaggcttcca tctcttacag ggggaggctt ccagttctta cagggggagg
     1801 cttccagctc tgacaggggc ggggtggctc tcggctcttc aacatgacca gtactgctca
     1861 aagttttata cgagacagga gagaccatcg gatgcacttt taaaagcaaa tatgaaacaa
     1921 tactttccgt tcagatgcac tgtttcttta tagattttct gttgttttgc tgtagctgta
     1981 tttgtcttct gtttggactt ttgcgttgta aatatacatt atacagacat tttattcaag
     2041 cttgaaaagg agaacgtggc gaatgctaac ggttctgaac tttcccagtg ttcttgaaga
     2101 ctgcacagca gccgggccgt gaatgttgat aattgagttt gtcaataaga ctgacagtgc
     2161 ccatctactg aatctacctc tgtttagaat caaatgtaag gacaaaaagc ttccgaagca
     2221 tgaaatcctg tcagactgag ttagagtgtg gtcatcttta ttacttcaga ttaaatcact
     2281 gtgctgtatg gtctatttca caaataatgg caacagaaaa cttcggtttt ttatgaagct
     2341 gatgtattta tggataaaaa tggcagttat gcagagagaa gctattcatg ttgatcacaa
     2401 tactaaccta taaaacaata gtttgtgtat tgttcacata aaatattatt ctagtatatc
     2461 ttatatttta tccagagaag ctaccctctc tggaatgtat ttattttcac tcttcatttt
     2521 aaagaagatc atgacagttg atcatgaatc tatattgctg catacctaaa actaattatt
     2581 tcctctgatt tttcagaaga tcttgaaaca tttactctct gtataataat ggactggagt
     2641 acttgaatgg cagaagtatg ctgaggaaat caccttgttc tgtagtaaat attgttaagt
     2701 gcatttagtg tttaagtgag cggtactggt gagaactgcg gacggttacg taatatgtca
     2761 aagtctgtgt tagggacctt ggggacgcat ggcaggtcac acgtgctgct gactgaacta
     2821 aggggtggac ggcctttgca gcagctcggt cagtctcact tacgctttgt gagttaacag
     2881 caaaaagtct cttgaaatgt gaaagtctaa aggttttgat agaaaattta aatttttttg
     2941 catatgtgtg ttatttccat agaactgtgc ttggtagaat tttctaagca gatgtggtat
     3001 tgttgaactc aatttttttt atttatagtt atatacaggt tatgtatata tttagttatt
     3061 acttaaggat acttacgtaa actctaaatt acaactcttg taagatggga actaaaacaa
     3121 ttttgatatg attcatagtt tattctataa agaaagattc atttatgata gcatttataa
     3181 tatttctgct gagaatcaga ggcatgtgat ataggagtca tttcaaatag taggacactg
     3241 taaactatat atcatgaatc taagctttta gcaagacaat taaactccac aaccatgaaa
     3301 tctaggttta aacgttttcc atagcaccaa ctgcatctgt cagtcttttt ataccattaa
     3361 gtagaggatt gtgtctgctc tttttattat aatggacgtt atagagttaa gtatgttatg
     3421 tacattcaaa gaaacagggt agtgatataa aagttaccaa atcgatgggt gagtttatca
     3481 aatgaacact gttttatggt gccagcgttt ctaagttaag atgacagggt attcgacagt
     3541 ttgtaatcag ttgttgatca gcataattca aacttagcca gctgtgcctg ctttgaggat
     3601 gcagtagtca ctatagcaag cctctaagcc aaatcttcca aaaagtagtt cttatagaag
     3661 aaattatatg tgtgtgtaat atatatatat gtatatatat tatgtgtgtg tgtatatata
     3721 tatatgtata tatatgtatg tgtgtatgta tatgtatgta tgtgtatgta taaaatgttt
     3781 gcaggcacat aggatgagtg acccgtcaaa ggagatttta gaacttatca gtgggacaaa
     3841 tgttgaattt ctaaatgcag aacatggtca ttctttgaat atttaagtac aaatattatt
     3901 tcttggatta gatttgaatg caaaggccac tttaaagcct agttcctttt tgtcggacta
     3961 agagcaagag ccagctgtgt aagagcacca ctaaaatgcc ccggtgtttg cctccatcat
     4021 cactgtccct gtgacacaac tcagtaagtt gcttttttaa gatttgtgac acttatatgt
     4081 gataaatacc ttgccaaata aaataaatgt atgacatgaa tgcaaatacc aagaaaaatc
     4141 ctgagtctat ttaactaagt ttaattgaat tttcttgaac ttgaatttct actgattaaa
     4201 ctatgcaatc atgcttattg ttttataaac acatgatgca ctggcctggg tttttcttgt
     4261 gttgttttcc tgtgttgtaa gttttaattt gaaagattat cctaacccaa tttttagtgt
     4321 tcttaacttt tagtgtcatc tggcacttat cggtagcagt ggaagctgga acagggtatt
     4381 ttggttttgg ttttaaagta actctgctgg cacagaaatg cccccccccc ccctctcccc
     4441 ccccccccct ctctttttcc tgtaacctgt ttgcagttaa agatggacat acagggtgaa
     4501 gaactgaaaa agcgtttctc tctgctttgg tagatttttt ttcttctgta taaaggagta
     4561 ttatagaaaa acgtaaacat aaaaatgtct ttgtggattt cgttagtgtt gtaaattcag
     4621 caatctactg gttgctaaat tgtgatactg tgatgtaaaa tgaactcctg tacttttcag
     4681 tacatagcaa gcactgctgg ttttgaaatg tgaccgtcat gctgttagga gccaatataa
     4741 tagggatcta aaacactatt gtctccctga taggaaaaca agatggatga gacaagacga
     4801 ggccagatga ggcgagatgt ggtgattttc acataactaa ataaacagac atttgaacat
     4861 tatgcaagat tatgaaatgt tacactctac taaacacaat aaaatactat tttacaattg
     4921 ta
//
