LOCUS       XM_039108963           17207 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus lysine methyltransferase 2C (Kmt2c),
            transcript variant X1, mRNA.
ACCESSION   XM_039108963
VERSION     XM_039108963.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039108963.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17207
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..17207
                     /gene="Kmt2c"
                     /note="lysine methyltransferase 2C; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 62 ESTs, 3 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     56 samples with support for all annotated introns"
                     /db_xref="GeneID:502710"
                     /db_xref="RGD:1587205"
     CDS             270..15281
                     /gene="Kmt2c"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase 2C isoform
                     X1"
                     /protein_id="XP_038964891.1"
                     /db_xref="GeneID:502710"
                     /db_xref="RGD:1587205"
                     /translation="MSSEEDRSAEQQQPPPAPPEEPGAPAPSPAAADKRPRGRPRKDG
                     ASPFQRARKKPRSRGKSTVEDEDSTDGLETTETENIVETAEVKEQSVEEDAETEVESS
                     KQPASALQRSVSEDSAHSLVSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRVTPGL
                     TLPWKDQPSNKDVGDSGIATCEKIQNYAPRKQRGQRKERSLQQSIVSCVSVSTQTACE
                     DQPGKLWDELSLVGLPDAIDVQALFDSTGTCWAHHRCVEWSLGICQMEEPLLVNVDKA
                     VVSGSTERCAFCKHLGATIKCCEEKCTQMYHYPCAAGAGTFQDFSHFFLLCPEHIDQA
                     PERSKEDANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLRRAGWQCPECKVCQ
                     NCRQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRSSAQWH
                     HNCLICDTCNQQQDNLCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKPTDQELDSQL
                     KEEYICMYCKHLGAEIDPLHPGNEVEMPELLPTDDSSGMEIEGTEDEVVFLEQTVNED
                     VSGHQSPPGIVPDAVQVYTEEPQKSDPLESPDTVGLITSESSENKTNPDLANEISHEV
                     DTEKTEMFYKEGLVCEEDQSEDRMEVTENIEVLPHQTIVPQEELLPSEGSEVAPEEPS
                     PSESAVELAAPEALVSPHSESSLSHKGPLVIERVQEEMEQKENSEFPTGCEDFEMTLA
                     VDGCVKGSSCQGDKSAELPAEEESPFSSGTDLNKADVSSSSTLRPDLPSCDMLHGYPS
                     AFNSAAGSVMPTTYISVTPKIGMGKPAITKRKFSPGRPRSKQGAWSNHNTVSPPSWSP
                     DIAEGREIFKPRQLSGSAIWSIKVGRGSGFPGKRRPRGAGLSGRGGRGRSKLKSGLGA
                     VVLPGVSAADISSNKDEEENSMHNTVVLFSSSDKFTLHQDMCVVCGSFGQGEEGRLLA
                     CSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHT
                     YCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSSCPVCCR
                     NYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPVSNVPSSDC
                     CDSSLVAQIVTKVKELDPPKTYTQDGVCLTESGMSQLQSLTVTAPRRKRTKPKLKLKI
                     INQNSVAVLQTPPDIQSEHSRDGEMDDSREGELMDCDGKSESSPEREAGDDETKGIEG
                     TDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKAKRSVVRKDSSGSISEQLSNRDDGWRE
                     QFPDTLVDEPVSVADSTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQNKLS
                     VDNLSEDAAQLSYKTGFMDPSSDPLLCSSSASAKPGTQGTADDPLADISEVLNTDDDI
                     LGIISDDLAKSVDHSGLDLCTFQVGSSPFPLDIGPIADDASSLPQPSVSQSSRPLSEE
                     QLDAILSPELDKMVTDGAILGKLYKIPELGGKDVEDLFTAVLSPAPTQPAPLPQPPPP
                     QPLPVHTQDVFSRMPLMNGLIGPSPHLPHHSLPAGSALGTFPAIAQSPYTDVRDKSLA
                     FNVMASDANSSWVPTAPSMEGENDSLSNAQRSTLKWEKEEALGEVATVAPVLYTNINF
                     PNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQ
                     QQQDSIDPTSRIDSDLFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVK
                     NEQQQQQQQQQQQQQQQQQQQQQQQQQQLASQHLLVAPGSDPPSSGAQSPLTPQTGNG
                     SVSPAQTFHKDLFSKHLPSTPASIPSDDVFVKPQPPPPPSTPSRIPNQESLSQSQNSQ
                     PPSPQMFSPGSSHSRPPSPVDPYAKMVGTPRPPPVGHSFPRRNSVTPVENCVPLSSVP
                     RPIHMNETSATRPSPARDLCASSMTNSDPYAKPPDTPRPMMTDQFPKPFSLPRSPVIS
                     EQSTKGPLAAGASDHFTKPSPRTDAFQRQRLPDPYAGPSLTPAPLGNGPFKTPLHPPP
                     SQDPYGSLSQASRRLSVDPYERPALTPRPVDNFSHNQSNDPYSQPPLTPHPAMGESYT
                     HSSRAFSQPGTISRSASQDPYSQPPGTPRPVIESYSQTSGTARSNQDPYSQPPGTPRP
                     NTIDPYSQQPPTPRPSPQTDMFVTSVASQRHTDPYTHHLGPPRSGISVPYSQPPAAPR
                     PRTSEGFTRSSSARPALMPNQDPFLQAAQNRVPGLPGPLIRPPDTCSQTPRPAGPGLT
                     DTFSHASPSGVRDPYDQPPMTPRPHSESFGASQVVHDLVDRPVPGSEGNFSTSSNLPV
                     SSQGQQFSSVSQLPGPVPTSGGTDTPNTVNMSQADTEKLRQRQKLREIILQQQQQKKI
                     ASRQEKGPQDTAVVPHPLPLPHWQPESINQAFTRPPPPYPGNTRSPVIPPLGPRYAVF
                     PKDQRGPYPPEVAGVGMRPHGFRVGFPGASHGPMPSQDRFHVPQQIQGSGIPPNIRRP
                     MSMEMPRPSNNPPINNPVGLPQHFPPQGLPVQQHNILGQAFIELRHRAPDGRSRLPFA
                     ASPGSAMESPSHPRHGNFLPRPDFPGPRHTDPIRQPPQCLPNQLPVHANLEQVPPSQP
                     EQGHPAHQSSIVMRPLTHPLSGEFSEAPLSTSTPTETPPDNLEIAGQSSDGLEEKLDS
                     DDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKGDDLDTLDNLETNDPNLDDLL
                     RSDEFDIIAYTDPELDLGDKKSMFNEELDLNVPIDDKLDNQCVSVEPKIRDQGDKTMV
                     LEDKDLPQKKSSGISEIKTEALSPHSKEEPESDIKNCDDSRGDAEIACSQASGQTSHS
                     DRGKPSLLTTDQEMLEKRNNRENAAPGVCAIQESTPLPAQDVMNSCDITGSTPVLSSL
                     LSNEKCDSSDIRPSVSSPPTLPISPSTHGSSLPPTLIPPGPLLDNTMNSNVTVVPRVN
                     HAFSQGVPVNPGFLQGQSSVNHLGTGKPTNQTVPLTNQSSTSGMPGPQQLMMPQTLAQ
                     QSRERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIM
                     KAKMVALKGINKVMAQNSLGMPPMVMSRFPFMGPSMAGVQTSEGQTLMPQAVAQDGSI
                     THQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQQKYLEEQIGAHRKSKKALS
                     AKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQ
                     QQQQQQQQQQQQQQQQQQCALAPPILMPGVQPQPPLVPGASPLTMSQPNFPMVSQQLQ
                     HQQHTAVISGHTSPARMPGLPGWQSSSAPAHLPLNPSRIQPPTAQLSLKTCTPAPGAV
                     SSANPQNGPPPRVEFDDNNPFSESFQERERKERLREQQERQRVQLMQEVDRQRALQQR
                     MEMEQHGLMGAELANRTPVSQMPFYASDRPCDFLQPPRPLQQSPQHQQQIGPVLPQQT
                     VQQGSVNSPPNQTFMQTNERRQVGPTPFVPDSPSASGGSPNFHSVKQGHGNLSGSSFQ
                     QSPLRPPFTPILPGKPPVANSSVPCGQDPAVTAQGQNFSGSSQSLIQLYSDIIPEEKG
                     KKKRTRKKKKDDDAESSKAPSTPHSDCTAPPTPGLSETTSAPAVSTPSELPQQRQQEA
                     VEPVRVPTPNVATGQPCIESENKLPSSEFIKETSSQQTPVSSEADKPSGEASNKSEER
                     KLETAEIQPCPSQEDTKVEEKTGSKIKDTAAGPVSSIQCPSNPARTPVTKGDTGNELL
                     KHLLKNKKASSLLTQKPEGTLSSDESSTQDGKLVEKQNPAEGLQTLGAQMQGGFGGGN
                     SQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAVCSSSDSFTHLKQQL
                     SLLPLMEPIIGVNFAHFLPYGSGQFNSGTRLLGTFGSAALEGVSDYYSQLIYKQNNLS
                     NPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTRALGPKPFQLPFRP
                     QDDLLARAIAQGPKTVDVPASLPTPPHNNHEELRIQDHYGDRDTPDSFVPSSSPESVV
                     GVEVNKYPDLSLVKEEPPEPVPSPIIPILPSISGRDSESRRNDIKTEPGTLFFTSPFG
                     SSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLV
                     SSHRINPGLEYRQHLLLRGPPPGSANPPRLATSYRLKQPNVPFPPASNGLSGCKDSSH
                     GIAEGTSLRPQWCCHCKVVILGSGVRKSFKDLTFANKGSRESTRRTEKDIVFCSNNCY
                     ILHSTTAQAKISDNKEPLPSLPQSPMKEPSKAFHQYSNNISTLDVHCLPQFQEKVSPP
                     ASPPITFPPAFEAAKVESKPDELKVTVKLKPRLRTVPVGLEDCRPLNKKWRGMKWKKW
                     SIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPAR
                     LLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHR
                     FRCTNIYHFTCATKAQCMFFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQ
                     IASIVQRGERDHTFRVGSLIFHAIGQLLPQQMQAFHSSKALFPVGYEASRLYWSTRYA
                     NRRCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDSSPKDVWDKILEPVACVRKKSEM
                     LQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGC
                     ARAEPKMSAHVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRRMK
                     TEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGV
                     YMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSNRRIQKGEEL
                     CYDYKFDFEDDQHKIPCHCGAVNCRKWMN"
ORIGIN      
        1 gcccgcttgc ccgccgcccc ccgccggccc ctgcgcgccg agtgcgcgcg cccgcgccga
       61 tgtgtgtgag tgcgtgtcct gctagctcca tgttgccgcc tctcccggta cctgctgctg
      121 ctgctgctcc cggggctgcg ggaaatgcga gaggctgagc cggggaggag caactcgagc
      181 agcagcagcg gcggcggctg cggccgctgc ggcgggagga gccccccagg aggaggacgg
      241 ggatccatgt gtctttcctg gtgactagga tgtcgtcgga ggaggaccgg agcgcggagc
      301 agcagcagcc gccgccagca ccccccgagg agcccggagc cccggccccg agccccgcag
      361 ccgcagacaa aagacctcgg ggccggcctc gcaaagatgg cgcttcccct ttccagagag
      421 ccagaaagaa gcctcgaagt agaggaaaat ctacagtgga agatgaggac agcacggatg
      481 gactggagac gacggagaca gaaaatattg tggagacagc agaagtcaaa gaacaatctg
      541 tggaggagga cgctgagaca gaagtggaga gcagcaagca gccagcctca gctcttcagc
      601 ggtctgtgtc tgaggactct gcacactccc tggtctctgt cggtgtagaa gccaaaatca
      661 gtgaacagct ctgcgccttt tgttactgtg gggagaaaag ttccttagga caaggagact
      721 tgaaacaatt cagagtaaca cctggactta ctttaccttg gaaagatcaa ccttctaaca
      781 aggacgtcgg tgacagcggc attgcaacct gtgagaaaat acagaactac gctccacgaa
      841 aacagcgagg acagagaaaa gagcgatctc tccagcagag tattgtttct tgtgtaagtg
      901 taagcacgca gacagcttgt gaggaccagc ctggcaagtt atgggatgaa ctcagtctgg
      961 ttggccttcc agatgccatt gatgtccaag ccttatttga ttccacaggc acttgctggg
     1021 ctcatcatcg atgtgtagag tggtcactgg gaatatgcca aatggaagag ccattattag
     1081 tgaacgtgga caaagctgtt gtctcaggga gcacagaacg ttgtgcattt tgcaaacacc
     1141 ttggagccac tatcaaatgc tgtgaagaga agtgtaccca gatgtaccat tacccgtgtg
     1201 ctgcaggggc cggcaccttt caggacttca gtcacttctt ccttctgtgt ccagagcaca
     1261 tcgaccaagc tcctgagaga tcaaaggaag atgcaaactg tgcagtgtgt gacagcccgg
     1321 gagatctctt agatcagttc ttttgtacca cctgtggtca gcactaccat gggatgtgcc
     1381 tggacatagc tgttactcca ttaaggcgtg ctggttggca atgtcctgag tgcaaagtgt
     1441 gccagaactg cagacaatcg ggagaagata gcaagatgct ggtgtgtgat acttgtgaca
     1501 aagggtatca tactttttgt ctccaacctg ttatgaaatc agtgccaacc aatggctgga
     1561 aatgcaaaaa ttgcagaatc tgtatagaat gtggcacacg atctagtgct cagtggcacc
     1621 acaactgtct gatatgcgac acttgtaatc agcagcaaga taatttatgt cctttttgtg
     1681 ggaagtgcta ccatccagaa ttgcagaaag acatgctcca ctgtaatatg tgtaagagat
     1741 gggttcactt agaatgtgac aaaccaactg atcaggaatt ggattctcag ctcaaagaag
     1801 aatacatctg catgtactgt aaacacttag gagctgagat agatccctta catccaggga
     1861 atgaagtgga gatgcctgaa cttctaccca cagatgattc cagtggaatg gaaattgaag
     1921 gcactgaaga tgaagtggtg tttctggagc agacagttaa tgaagatgtc agtggtcacc
     1981 agtcccctcc tggaattgtt ccagatgcag ttcaagttta cactgaagag ccccagaaaa
     2041 gtgatccact agaaagccct gacacagttg gtctcattac ttctgaatca tctgagaata
     2101 aaaccaatcc tgatttggca aatgagattt ctcatgaagt tgatactgaa aaaacggaaa
     2161 tgttttataa agaggggctt gtttgtgagg aagatcaaag tgaggacaga atggaagtga
     2221 cagaaaacat tgaagtcctt ccacaccaaa ccattgtgcc gcaagaggaa ctgctgccct
     2281 ccgagggctc tgaggtggca cctgaggagc caagcccttc agagtcagct gtggagcttg
     2341 ctgcaccaga agccttagtg tccccacaca gtgaaagttc cttatctcat aagggaccgt
     2401 tggtgataga aagagtacaa gaagaaatgg aacagaagga aaattctgaa ttccccactg
     2461 ggtgtgagga ttttgaaatg actcttgctg ttgacggttg tgtcaaaggt agttcatgcc
     2521 aaggagacaa atcagctgag ttaccagctg aggaagagtc accattctca tcaggaactg
     2581 acctgaacaa ggcggacgtg tcttcctcct ccacacttcg tccagacttg ccttcatgcg
     2641 acatgctgca cggttaccct tcagctttca actctgctgc tggaagcgtc atgccaacaa
     2701 catacatctc tgtcactcca aaaattggca tgggtaaacc agctattacc aaaagaaaat
     2761 tttctcccgg tagaccccgg tccaaacagg gggcttggag taaccataat acagtgagcc
     2821 caccctcctg gtccccagac attgcagaag gccgggaaat ttttaaaccc aggcagcttt
     2881 ctggcagtgc catttggagc atcaaagtgg gccgagggtc tggatttccg gggaagcgga
     2941 ggcctcgtgg tgctgggctg tcagggcgag gcggcagagg cagatctaaa ctaaaaagtg
     3001 gactcggagc tgttgtgtta cctggggtgt ctgctgcaga tatttcatca aataaagatg
     3061 aagaagaaaa ctctatgcac aatacagttg ttttattttc tagtagtgac aagttcactt
     3121 tgcatcagga tatgtgtgta gtttgtggca gtttcggcca aggagaagaa ggaagattac
     3181 ttgcctgttc acagtgtggt cagtgttacc atccatattg tgtcagtatt aagatcacta
     3241 aagtggttct tagcaaaggt tggagatgtc ttgagtgcac tgtgtgtgag gcctgtggga
     3301 aggcaactga ccctggaaga ctcttgctgt gtgatgactg tgacataagc tatcatacct
     3361 actgcctaga ccctccattg cagacagttc ccaaaggagg ctggaaatgc aaatggtgtg
     3421 tttggtgcag acactgtgga gcaacatctg caggcttgag atgtgaatgg caaaacaatt
     3481 acacacagtg tgctccgtgt gccagcctgt cctcctgccc agtctgctgt cggaactaca
     3541 gagaagagga cctcattctt cagtgtagac agtgtgatag gtggatgcat gcagtttgtc
     3601 aaaacttaaa tactgaggag gaagtggaaa atgtagcaga cattggtttt gactgtagca
     3661 tgtgcagacc ctatatgcct gtgtcaaatg tgccttcctc agactgctgc gactcttctc
     3721 ttgtggcaca gatcgtcaca aaagtaaaag agctagaccc acctaagacc tacacccagg
     3781 acggtgtgtg tctgaccgag tcagggatga gtcagctaca gagcctcaca gtcacagctc
     3841 ccaggagaaa acgcacaaaa ccaaaactga aattgaagat tataaatcag aatagtgtgg
     3901 ctgttcttca gacccctcca gatatccagt cagaacactc aagagacgga gaaatggacg
     3961 atagtcgaga aggagaactt atggattgtg atgggaaatc tgaatctagt cctgagcggg
     4021 aagctggaga tgatgaaact aagggaatag aaggaacaga tggcgtaaag aagaggaaaa
     4081 gaaaaccata tagacctggt attggtggat ttatggtacg gcaaagaagt cggacaggac
     4141 aaggaaaagc caaaagatct gtggtcagaa aagattcttc aggctctatt tctgagcagt
     4201 tatctaacag agacgatggc tggagggagc agttcccaga tactctggtg gatgagcctg
     4261 tctccgttgc tgacagcact gagaaaataa agaagagata ccgaaaaagg aaaaataagc
     4321 ttgaagaaac ttttcctgct tatttacaag aagcattttt tggaaaagat cttctagata
     4381 ccagcagaca aaacaagctg agtgtagata atctgtccga agacgcagct cagctttcat
     4441 ataaaacagg tttcatggat ccttcctcag atccgctgct gtgttcatca tctgcttcag
     4501 caaaacctgg gactcagggt actgctgatg acccattagc tgatatttct gaagtcttaa
     4561 acacagatga tgacattctt ggaataatct cagatgatct tgcaaaatca gttgatcatt
     4621 caggtcttga tttatgcact ttccaggttg ggagctcccc cttccctttg gatattggcc
     4681 ccattgctga tgatgcttcc tctttgcctc agccaagtgt cagtcagagt tcacgaccat
     4741 taagtgaaga acagctagat gccatcctca gtcctgaact agacaaaatg gtcacagatg
     4801 gagcaatact tggaaagtta tataaaattc cagagcttgg aggaaaggat gttgaagact
     4861 tgttcactgc tgtacttagt cctgccccca cccagccggc tccattgcca cagccccctc
     4921 caccacagcc actgccagtg cacactcagg atgttttttc ccggatgcca ctcatgaatg
     4981 gccttattgg acccagtcct catctcccac atcattcttt gcctgctgga agtgcactgg
     5041 ggactttccc tgctatagca caatcccctt atactgatgt cagggataaa agtctagcat
     5101 ttaatgtaat ggcaagtgat gctaacagct cctgggtgcc gacagctcca agtatggagg
     5161 gggaaaacga cagcctgtca aatgcccaga ggagcacact gaagtgggag aaggaggagg
     5221 ctcttggtga ggtggcaaca gtggcaccag tcctctacac aaatattaat ttccccaact
     5281 taaaggaaga attcccagat tggactactc gagtgaaaca aattgccaag ttgtggagaa
     5341 aagccagctc tcaggaaaga gcgccatatg tgcaaaaagc cagagataac agagctgctt
     5401 tacgcatcaa taaagttcag atgtcaaatg attctatgaa gaggcaacaa cagcaagaca
     5461 gcatcgatcc cacctcacgc atcgattcgg atctttttaa agatccttta aagcagaggg
     5521 aatcagagca tgaacaggaa tggaagttta gacagcaaat gcgtcagaaa agtaagcagc
     5581 aagctaaaat tgaagccaca cagaagctgg aacaagtgaa gaatgaacag cagcagcagc
     5641 agcagcaaca gcaacaacaa caacaacaac aacaacaaca acaacaacaa cagcaacaac
     5701 aacaacttgc ttctcagcac cttctagtag cacctggttc agatcctccc agtagtggag
     5761 cacagagtcc cttgacacct cagactggca atgggagtgt gtctcctgca cagacattcc
     5821 ataaagacct gttctccaaa cacctcccca gtactcctgc ttccatacct tcagatgatg
     5881 tgtttgtcaa accacaacct ccaccccctc cttcaacccc atcccgtata cctaatcagg
     5941 aaagtctgtc tcagtcccag aattctcagc caccttctcc acagatgttc tcacctggat
     6001 catcccactc cagaccaccc tctccagtgg atccttatgc aaaaatggtt ggtactccta
     6061 gaccgcctcc tgttggccat agttttccaa gaagaaattc tgttacacca gtggaaaact
     6121 gtgtgccttt atcttcagta cctaggccca ttcatatgaa tgaaacatca gccacaaggc
     6181 catccccagc cagagactta tgtgcttcct ccatgacaaa cagtgacccc tatgcaaagc
     6241 ctccagatac acctaggcca atgatgacag atcagtttcc caaacctttt agccttccta
     6301 ggtcccctgt gatttcagaa caaagtacaa aaggtcctct tgcagctgga gccagtgatc
     6361 actttaccaa gccttctcct agaacagacg cctttcagag gcaacggctg cctgacccat
     6421 atgcagggcc atcgttgaca cccgccccac tgggtaatgg gccgtttaag acccctctgc
     6481 accctcctcc atctcaggat ccatatggat ctttgtcaca ggcatcaaga cgactctctg
     6541 ttgaccctta tgaaaggcct gccttgacac caaggccagt agataatttt tctcataatc
     6601 agtcaaatga tccatatagc cagcctcccc taactccaca cccagctatg ggtgaatctt
     6661 atactcactc ttcaagggct ttttctcagc ctggaaccat atcaaggtca gcatctcagg
     6721 acccatattc acaaccccca ggaactccac gtcctgttat agaatcttac tcccaaacct
     6781 caggaacagc tcgatccaat caagatcctt attcccaacc tcctggtact ccccggccta
     6841 acactattga cccatatagt cagcaaccac ctacccctag gccttctcca cagacagata
     6901 tgtttgttac gtctgtggca agtcagagac acactgatcc atatactcat catcttgggc
     6961 cgccgagatc tggaatttct gttccctatt ctcagccacc agcagcacca aggccaagga
     7021 cttcagaggg ttttactcgg tcctctagtg caagaccagc cctcatgcca aaccaggatc
     7081 cttttttgca agcagcacaa aaccgagtac caggtttacc tggcccttta ataaggccac
     7141 ctgatacatg ttcccagact cccagaccag ctgggcctgg ccttacagac acattcagtc
     7201 atgcttcccc atctggtgtt cgtgatccct acgatcagcc tccaatgact cccaggccac
     7261 attctgagtc tttcggggct agtcaagttg tccacgatct tgttgaccgt ccagttcctg
     7321 gatcagaggg aaactttagc acatcttcaa accttcctgt aagctcccaa ggacagcaat
     7381 tttccagtgt ctcccagctt cctggacccg tgccaacctc aggaggaact gacacaccga
     7441 acaccgtgaa catgtctcaa gctgacaccg agaaattgag acagcggcag aagctgcgtg
     7501 aaatcattct ccagcaacag cagcagaaga agattgctag tcgccaggag aaggggcctc
     7561 aggacacagc cgtagtacct caccctctgc cccttccaca ctggcagcca gagagcatca
     7621 accaggcttt cacccgacct ccacctccct atcctgggaa cactcgatca cctgttatcc
     7681 ccccactagg acctagatat gcagttttcc ccaaagatca gcgtggaccc tatcctcctg
     7741 aggttgctgg tgtggggatg agacctcatg gatttagagt tggatttcca ggagctagcc
     7801 atggtcccat gccaagccaa gatcgtttcc atgtgcctca gcaaatacaa ggatctggaa
     7861 ttcctccaaa cataagaaga ccaatgtcta tggaaatgcc tagaccttca aataacccac
     7921 caataaataa tccagttggg cttcctcagc atttcccacc acagggtctg ccagttcagc
     7981 agcataatat actaggccaa gcttttattg agctgaggca cagagctccg gatggaaggt
     8041 cacggttgcc atttgctgct tctcctggca gtgctatgga gtcaccttct catcccagac
     8101 atggaaattt ccttcccaga cctgattttc ctggtcctag acacacagac cccataagac
     8161 aacctcccca gtgtctacct aatcagctac ctgtgcatgc aaatttagag caggtcccac
     8221 cttctcagcc agagcaaggt catcctgccc accaatcttc tattgtcatg aggcccctaa
     8281 ctcatccttt aagtggtgaa ttttctgagg ctcctttgtc aacatctacc ccaactgaaa
     8341 cacccccaga taacttagag atagctggtc agtcttctga tggtctggag gaaaaactag
     8401 actctgatga tccttctgtg aaagaactgg atgtcaaaga tcttgaggga gtcgaagtca
     8461 aagatttgga tgatgaagat ctagaaaatt taaatttaga cacagaggat ggcaagggtg
     8521 atgacctgga cactttagat aatttggaaa ccaatgaccc taacctggat gacctcttaa
     8581 ggtcagatga atttgatatc atagcgtaca cagatccaga acttgactta ggggataaaa
     8641 aaagcatgtt caatgaggaa ttagacctta atgttccaat tgatgataag ctagataatc
     8701 agtgtgtatc tgttgaaccc aaaataaggg atcaaggaga caaaactatg gttcttgaag
     8761 ataaggattt gccacagaaa aagtccagtg gtatcagtga gataaagaca gaagccctgt
     8821 ctccccactc taaagaagaa ccagagagtg acattaaaaa ctgcgatgac agtagaggag
     8881 atgccgagat agcgtgctca caggcttctg gtcagaccag tcacagtgat cgaggaaagc
     8941 cttctctgct gactactgat caagagatgc ttgagaaaag aaataaccgg gaaaatgcag
     9001 ctcctggtgt ctgtgccatt caagagtcca ctcctctgcc tgctcaagac gtgatgaact
     9061 cttgtgacat aacaggatcg actccagttc tctcgagttt actctcgaat gaaaagtgtg
     9121 atagctctga cattaggcct tcagtgtctt ccccaccaac tctccccatc tcaccatcca
     9181 ctcatgggtc aagtttgcct cctactttaa taccacctgg ccctctcttg gataatacca
     9241 tgaattctaa tgtaacagtg gtccctaggg taaaccatgc attttctcag ggtgtgccag
     9301 taaatccagg attccttcag ggtcagtcat cagtgaacca tttagggaca gggaaaccta
     9361 cgaatcaaac tgtgcctctc acaaatcagt ccagcaccag tggcatgcct ggaccacagc
     9421 agctaatgat gcctcaaaca ttagcccagc agagcagaga gaggcccctc cttctagagg
     9481 aacagcctct gcttctacaa gatcttttgg atcaagagag gcaggagcag cagcagcaaa
     9541 gacaaatgca agctatgatt cgtcagcggt cagaaccatt cttccctaac attgatttcg
     9601 atgcaataac agatcctata atgaaagcga aaatggtagc ccttaaaggc ataaataaag
     9661 tgatggcaca gaacagcctg ggcatgccac caatggtgat gagcagattc cccttcatgg
     9721 gtccatccat ggctggagtg caaaccagtg aaggccagac cctaatgcca caagctgtag
     9781 cccaggatgg cagtataaca catcagattt ctaggcctaa tcctccaaat tttggtccag
     9841 gctttgtcaa tgactctcag cggaagcagt atgaagagtg gctccaggag actcagcagc
     9901 tgcttcagat gcagcagaag tatcttgagg aacaaattgg tgcgcacaga aaatctaaga
     9961 aggccctgtc agccaaacag cgcacggcca agaaggcagg gcgagagttc ccagaagagg
    10021 acgcagagca gctcaagcat gttactgagc agcagagcat ggttcagaaa caacttgagc
    10081 agattcgtaa acaacagaaa gagcatgctg agctgattga agattaccgg atcaagcagc
    10141 agcagcagca gcagcagcag cagcagcagc agcagcagca gcagcagcag cagcagcagt
    10201 gcgccctagc ccctcccatc ctcatgccag gggttcagcc ccagccacct ctagttccag
    10261 gtgccagccc actcaccatg agccaaccca acttccccat ggtgtcacag cagcttcagc
    10321 accagcagca cacagcagtc atctctgggc acaccagccc tgctagaatg cccggcttac
    10381 ctggatggca atctagcagt gctcccgctc acctccccct taacccttct aggattcagc
    10441 ccccaactgc ccaactatct ttaaaaactt gtacaccagc cccaggggca gtgtcaagtg
    10501 caaatccaca gaatggacca ccacctcgag tagaatttga tgacaacaac cctttcagtg
    10561 aaagttttca agagcgagag aggaaggaac gcttacgaga acagcaggaa agacagcgag
    10621 tgcagctgat gcaagaagta gacagacaga gagctctaca gcagcggatg gagatggagc
    10681 agcatgggct tatgggtgct gagctagcca acaggacacc tgtttcccag atgccattct
    10741 atgcttctga cagaccttgt gactttttgc aacccccacg accccttcag cagtctccac
    10801 aacaccagca gcagataggg ccagttttac cacagcagac tgtccaacaa gggtctgtta
    10861 attcaccccc aaaccaaact ttcatgcaaa ccaatgagcg aaggcaggta ggacctaccc
    10921 cctttgttcc agattcacca tctgcttctg gtgggagccc aaacttccat tctgttaagc
    10981 aaggacatgg aaatctttct ggatccagct ttcagcagtc tccactgagg cctccattca
    11041 caccaatttt accaggaaag cctccggtag ccaatagcag tgtcccatgt ggccaagacc
    11101 ctgctgtaac agcacaggga caaaattttt caggatccag ccagtctctc attcagttgt
    11161 attctgacat aatcccagaa gaaaagggga aaaagaagag aacaagaaaa aagaaaaaag
    11221 atgatgatgc agaatccagc aaagccccat caactcccca ctccgactgc acagccccac
    11281 caaccccagg cctctcagaa actacctctg ctcctgcagt gagcacaccc agtgagctcc
    11341 ctcagcaaag acaacaggag gcagtggagc ccgtccgtgt ccccactcca aatgtggcaa
    11401 caggccagcc ttgtatcgag tcagaaaaca aacttcccag cagtgaattc ataaaagaaa
    11461 cttcaagtca acagacacct gtgagctcag aggcagacaa accttccggg gaggcctcca
    11521 acaaaagtga agagagaaag ctggagacgg ctgagataca gccatgccca agtcaggagg
    11581 acaccaaagt ggaagagaaa actggtagta agatcaaaga cactgcagct ggtcctgtct
    11641 cctccataca gtgtccttcc aatcctgcca gaacccctgt caccaaagga gacacaggaa
    11701 acgaactact gaagcacttg ttaaaaaata agaaggcctc ttcccttctc actcagaaac
    11761 ctgagggcac tttatcttca gatgaaagct ctacacagga tggtaaactg gtggagaagc
    11821 agaatccagc agaaggattg caaactttgg gggctcaaat gcaaggtggt tttggaggtg
    11881 gcaacagcca gttgccaaaa acagatggag gaagtgaaac caagaaacag cgaagcaaac
    11941 ggacacagag gacgggggaa aaagcagcac ctcgctcaaa gaaaaggaag aaggatgaag
    12001 aggaaaagca ggctgtgtgc tccagctctg actccttcac ccacttgaaa cagcagctct
    12061 ctctgctccc tctaatggaa ccgatcattg gagtgaactt tgcgcacttt cttccttatg
    12121 gcagtggcca atttaatagt gggactcgac ttctaggaac ttttggcagt gccgcccttg
    12181 aaggggtctc agactactat tctcagttga tctacaagca gaataattta agtaatcctc
    12241 caacaccccc tgcctctctt cctcctacac cacctcctat ggcttgccag aagatggcaa
    12301 atggttttgc aacgactgaa gaacttgctg gaaaagctgg cgtgttggtg agccacgaag
    12361 tcaccagagc tttaggaccg aagccatttc agctgccttt cagacctcag gatgacttgc
    12421 tagctcgagc cattgctcaa ggcccgaaga cagtggatgt tcctgcctct cttccaacac
    12481 cacctcacaa taatcatgaa gaattaagga ttcaggacca ctatggcgac cgggacactc
    12541 cagacagttt cgtcccctcg tcttctcctg agagtgtagt tggtgtggag gtgaacaagt
    12601 accccgacct gtcactggtg aaggaggagc ctcccgagcc tgtgccatcc cccatcattc
    12661 ccattctccc cagcatctct gggagagatt cagaatcaag aagaaatgac atcaaaactg
    12721 aaccaggcac tttatttttt acatcacctt ttggttcatc cccaaatggt cccagatcgg
    12781 gtcttatatc tgtggcaatc accctgcatc ctacagctgc tgagaacatt agcagtgttg
    12841 tggctgcgtt ttccgacctt cttcacgtga gaattcctaa cagctatgag gttagtagtg
    12901 ctccagatgt tccatccatg ggtttggtca gtagccacag aataaaccca ggtttggagt
    12961 atcggcagca tttgcttctt cgtgggcctc caccaggatc tgcaaatcct ccccgattag
    13021 caacctctta ccggctgaag cagcctaatg taccatttcc tccagcgagc aatggacttt
    13081 ctggatgtaa agattctagt catgggatag cagaaggcac atcactccgg ccacagtggt
    13141 gctgtcactg taaagtggtc attcttggaa gtggtgtgcg gaaatcattc aaggatctga
    13201 cctttgcgaa caagggttcc cgagagagca ccagaaggac ggaaaaggac attgtctttt
    13261 gtagtaataa ctgctatatt cttcattcaa caaccgcaca agcaaaaatt tcagacaaca
    13321 aggaacccct tccgtcactg ccacagtccc ctatgaagga gccttccaaa gcatttcacc
    13381 agtatagcaa caacatctcc accttggatg tacactgtct ccctcagttc caggagaaag
    13441 tctcccctcc tgcatcacct cctataacct tccctccagc ctttgaagcc gccaaagtag
    13501 agtccaagcc tgacgagctc aaggtgacag tcaaattaaa gcctcggctg aggacggtgc
    13561 ctgtcgggct ggaggattgt agaccactga ataaaaagtg gagagggatg aagtggaaga
    13621 aatggagcat tcatattgtc atccccaagg ggacctttaa accgccctgt gaggatgaga
    13681 tagatgaatt tctaaagaaa ttgggcactt cccttaaacc tgaccctgtc cccaaagact
    13741 atcgcaagtg ttgcttttgt cacgaagaag gtgatgggct aacagatggg ccagcaaggc
    13801 tgctcaacct ggacctggac ctctgggtcc acttgaattg tgctctgtgg tccacagagg
    13861 tctatgagac acaggctggt gccttaataa atgtggagct agcgctgagg agaggtctac
    13921 aaatgaaatg tgtcttctgt cataagacag gtgccaccag tggatgtcac agatttcgat
    13981 gtaccaatat ttatcatttt acttgcgcca ctaaagcaca atgcatgttt tttaaagaca
    14041 aaacaatgct ttgccccatg cacaaaccaa agggaatcca tgagcaagaa ttgagttact
    14101 ttgcagtctt caggagggtc tatgtgcaac gagatgaggt acggcaaatt gctagtattg
    14161 tgcaacgggg agagcgggac catacctttc gtgttgggag cctcatcttc catgccattg
    14221 gtcagctgct tccacaacag atgcaagcat tccactcttc gaaagcgctc ttccccgtgg
    14281 gctatgaggc cagccggtta tactggagta ctcgctacgc caaccgtcga tgccggtacc
    14341 tgtgttccat tgaggagaaa gacgggcggc ccgtgtttgt catcaggatt gtagagcaag
    14401 gccatgagga cctggtctta agtgattcat cacctaaaga tgtttgggat aaaattttgg
    14461 agcctgtggc atgtgtaaga aaaaagtcgg aaatgctgca gcttttcccc gcgtatttga
    14521 aaggagaaga cctgtttggc ctgactgtct ctgcggtggc acggatagct gagtcactac
    14581 ctggggttga ggcatgtgaa aactacacct tccggtatgg ccgcaatcct ctcatggaac
    14641 ttcctcttgc cgttaacccc acaggctgtg cccgtgcgga acctaaaatg agcgcccatg
    14701 tgaagaggtt tgtgttaagg cctcacacct tgaatagcac cagcacttca aagtcgtttc
    14761 agagcacagt cactggagag ctgaacgcac cgtacagtaa gcagtttgtc cactccaagt
    14821 catcacagta ccgcagaatg aagactgaat ggaaatctaa tgtgtatctg gcccggtctc
    14881 ggatccaggg actgggcctg tatgctgcta gagacattga aaaacacacc atggtcatcg
    14941 agtacattgg aacgattatt cgaaatgaag ttgcaaaccg gaaagagaag ctttatgagt
    15001 ctcagaaccg aggtgtgtac atgttccgca tggacaatga ccacgtgatt gatgccacac
    15061 tcacaggagg gcctgcaagg tacatcaacc actcctgtgc ccctaactgt gtggctgaag
    15121 ttgtgacctt tgagagagga cacaagatta tcatcagctc caacaggagg atccagaaag
    15181 gagaagagct ctgctatgac tacaagtttg actttgaaga tgaccagcac aagatcccat
    15241 gtcactgtgg agcggtgaac tgccggaagt ggatgaactg aatgcattcc ttgctatctc
    15301 accgggtggc tcgtccctag gaagaggcga ctcaacactt cattggattt tgcagacaga
    15361 aagatatttt tgttttctga ctttttgaaa aacagcttct ggagctctgc ttccccagcc
    15421 cttgtctgaa ggaagcgcag aggagccggc gaggctgccc cactgtgcgc tggggtcagc
    15481 agactcacag aatggtccag cacttttttt tcttttttcc ctttcccttt ttctttcctt
    15541 ccttttgttt ccttgtgggt gggttttgtt ttgttttgtt ttgttagtct cactaaggag
    15601 aaacttatac tggggcaaag agccggtggc tgccctgccc cagggtgggg gccttcctat
    15661 gaatgtaaga ctgaaatcac cagcgaaggg ggctgtccag agtgctggcc acgccttact
    15721 gacaggggca ggccctcagt ttaactaaaa gtggacacca ctgatcaagg aatgtactga
    15781 gaagacttcc ttagggatag agctaaggga taataacttg cactaaatac atttgaatac
    15841 ttgattccat gagtcagttt attgtagttt ttgatttctg taaaataaga gaaacttttt
    15901 gtatttatta ttgaataagt gaatgaagct atttttaaat aaaagttaga agaaagccaa
    15961 gctgctgctg ttacctgcag aactaacaaa ccctgttact ttgtacaaat atgtaaatat
    16021 tttgagaaaa acagtataaa aatagttatt gaccaaatgc taccaggcgc tgcagcagct
    16081 cgggtgctta taaccgtggt agggatgtta caatataatt ttgtgttctt aaatatgcca
    16141 ttataattat gtaataacca aaattgtgcc ccagtacgcc tgggcttttt ggacactgtc
    16201 tcttagtgct tgttttctac acctaactaa cttctgacag cagggcgtgt gctacagctc
    16261 cagcttttat ggctgctggc cattcagact aacgtttcat actatattgt ttcatactat
    16321 attgtttata gctgttgatg atcagactaa tgctccattt atattgttgc atccctactt
    16381 cttcagtcag gttttttgtg cttacaaatt tgtgataact gtgaataacg gcttaaacac
    16441 aaacccaaat ggaggctgaa ttttttcttc agcaaaagta gttttgatta gaaatttgtt
    16501 tccaacctca cagaatcatg taaacataga gtcatgtagc agggacctaa ccaactcctt
    16561 agccttctat ttaacataaa aatttgaaaa ataaaaaaaa gagagatgga gagagtgaga
    16621 tgtgattacg ctccagctgc aggactctgg caatggggtt tttcgaagat gtaattttaa
    16681 aatgtgtttg tatgaacttg tttgtttaca tttctttaat aaaaaacaca ctgttttgtg
    16741 tttgcttgta gaaacttaat cagcatttga accaggttag ctttttattt tgtacttaaa
    16801 attctggtac tgacacttca caggctaagt ataaaatgga gtttgtgtgc acaattcgag
    16861 tggactgtga gcttcgggta cacatcagtg gctcagctct cagcttgtaa tgtatatggc
    16921 atgatgtatt tttatcttac agaataaatc aattgtatat atttttctct tgataaatag
    16981 ctgtatgaaa tttgtttctt gaatattttt cttctcttgt acaatactct gacatcctac
    17041 cagtatttgt cctgccgagt tttgttgttt tctgttctgt aaaatagtat ctaatgttgg
    17101 caaaaattga attttttgaa gtatacagag tgttatgggt tttggaattt gtggacacag
    17161 atttagaaga tcaccattta caaataaagt attttacatc tatggaa
//
