LOCUS       NM_001108139           16584 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus lysine methyltransferase 2A (Kmt2a), transcript
            variant 1, mRNA.
ACCESSION   NM_001108139 XM_001067729 XM_236194
VERSION     NM_001108139.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 16584)
  AUTHORS   Zhang,L., Ye,X., Luo,S., Xu,X., Wang,S., Jin,K., Zheng,Y., Zhu,X.,
            Chen,D., Jin,J. and Huang,J.
  TITLE     Clinical features and next-generation sequencing landscape of
            essential thrombocythemia, prefibrotic primary myelofibrosis, and
            overt fibrotic primary myelofibrosis: a Chinese monocentric
            retrospective study
  JOURNAL   J Cancer Res Clin Oncol 149 (6), 2383-2392 (2023)
   PUBMED   35731275
REFERENCE   2  (bases 1 to 16584)
  AUTHORS   Guida,N., Mascolo,L., Serani,A., Cuomo,O., Anzilotti,S.,
            Brancaccio,P., Pignataro,G., Molinaro,P., Annunziato,L. and
            Formisano,L.
  TITLE     GATA3 (GATA-Binding Protein 3)/KMT2A (Lysine-Methyltransferase-2A)
            Complex by Increasing H3K4-3me (Trimethylated Lysine-4 of
            Histone-3) Upregulates NCX3 (Na+-Ca2+ Exchanger 3) Transcription
            and Contributes to Ischemic Preconditioning Neuroprotection
  JOURNAL   Stroke 52 (11), 3680-3691 (2021)
   PUBMED   34694864
REFERENCE   3  (bases 1 to 16584)
  AUTHORS   Libbrecht,C., Xie,H.M., Kingsley,M.C., Haladyna,J.N., Riedel,S.S.,
            Alikarami,F., Lenard,A., McGeehan,G.M., Ernst,P. and Bernt,K.M.
  TITLE     Menin is necessary for long term maintenance of meningioma-1 driven
            leukemia
  JOURNAL   Leukemia 35 (5), 1405-1417 (2021)
   PUBMED   33542482
REFERENCE   4  (bases 1 to 16584)
  AUTHORS   Shimoda,H., Doi,S., Nakashima,A., Sasaki,K., Doi,T. and Masaki,T.
  TITLE     Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex
            attenuates renal senescence in ischemia reperfusion mice by
            reduction of p16INK4a
  JOURNAL   Kidney Int 96 (5), 1162-1175 (2019)
   PUBMED   31570196
REFERENCE   5  (bases 1 to 16584)
  AUTHORS   Toro,C.A., Wright,H., Aylwin,C.F., Ojeda,S.R. and Lomniczi,A.
  TITLE     Trithorax dependent changes in chromatin landscape at enhancer and
            promoter regions drive female puberty
  JOURNAL   Nat Commun 9 (1), 57 (2018)
   PUBMED   29302059
  REMARK    GeneRIF: Preceding puberty, MLL1 changes the chromatin
            configuration at the promoters of Kiss1 and Tac3, two genes
            required for puberty to occur, from repressive to permissive. Mll1
            knockdown reduced Kiss1 and Tac3 expression, which delayed puberty
            and disrupted reproductive cyclicity.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 16584)
  AUTHORS   Sutherland,H.G., Mumford,G.K., Newton,K., Ford,L.V., Farrall,R.,
            Dellaire,G., Caceres,J.F. and Bickmore,W.A.
  TITLE     Large-scale identification of mammalian proteins localized to
            nuclear sub-compartments
  JOURNAL   Hum Mol Genet 10 (18), 1995-2011 (2001)
   PUBMED   11555636
REFERENCE   7  (bases 1 to 16584)
  AUTHORS   Fair,K., Anderson,M., Bulanova,E., Mi,H., Tropschug,M. and
            Diaz,M.O.
  TITLE     Protein interactions of the MLL PHD fingers modulate MLL target
            gene regulation in human cells
  JOURNAL   Mol Cell Biol 21 (10), 3589-3597 (2001)
   PUBMED   11313484
REFERENCE   8  (bases 1 to 16584)
  AUTHORS   Rozovskaia,T., Rozenblatt-Rosen,O., Sedkov,Y., Burakov,D., Yano,T.,
            Nakamura,T., Petruck,S., Ben-Simchon,L., Croce,C.M., Mazo,A. and
            Canaani,E.
  TITLE     Self-association of the SET domains of human ALL-1 and of
            Drosophila TRITHORAX and ASH1 proteins
  JOURNAL   Oncogene 19 (3), 351-357 (2000)
   PUBMED   10656681
REFERENCE   9  (bases 1 to 16584)
  AUTHORS   Yagi,H., Deguchi,K., Aono,A., Tani,Y., Kishimoto,T. and Komori,T.
  TITLE     Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice
  JOURNAL   Blood 92 (1), 108-117 (1998)
   PUBMED   9639506
REFERENCE   10 (bases 1 to 16584)
  AUTHORS   Thirman,M.J., Gill,H.J., Burnett,R.C., Mbangkollo,D., McCabe,N.R.,
            Kobayashi,H., Ziemin-van der Poel,S., Kaneko,Y., Morgan,R.,
            Sandberg,A.A. et al.
  TITLE     Rearrangement of the MLL gene in acute lymphoblastic and acute
            myeloid leukemias with 11q23 chromosomal translocations
  JOURNAL   N Engl J Med 329 (13), 909-914 (1993)
   PUBMED   8361504
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Apr 21, 2023 this sequence version replaced NM_001108139.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-461               JAXUCZ010000008.1  54088759-54089219   c
            462-531             JAXUCZ010000008.1  54062049-54062118   c
            532-3182            JAXUCZ010000008.1  54056409-54059059   c
            3183-3360           JAXUCZ010000008.1  54055546-54055723   c
            3361-3595           JAXUCZ010000008.1  54053934-54054168   c
            3596-3660           JAXUCZ010000008.1  54052097-54052161   c
            3661-4098           JAXUCZ010000008.1  54051216-54051653   c
            4099-4172           JAXUCZ010000008.1  54050992-54051065   c
            4173-4304           JAXUCZ010000008.1  54050228-54050359   c
            4305-4418           JAXUCZ010000008.1  54049660-54049773   c
            4419-4565           JAXUCZ010000008.1  54046950-54047096   c
            4566-4661           JAXUCZ010000008.1  54046563-54046658   c
            4662-4782           JAXUCZ010000008.1  54046217-54046337   c
            4783-4905           JAXUCZ010000008.1  54044453-54044575   c
            4906-5090           JAXUCZ010000008.1  54043394-54043578   c
            5091-5264           JAXUCZ010000008.1  54041997-54042170   c
            5265-5375           JAXUCZ010000008.1  54041167-54041277   c
            5376-5449           JAXUCZ010000008.1  54040816-54040889   c
            5450-5643           JAXUCZ010000008.1  54039817-54040010   c
            5644-5750           JAXUCZ010000008.1  54039410-54039516   c
            5751-5888           JAXUCZ010000008.1  54037503-54037640   c
            5889-6047           JAXUCZ010000008.1  54036042-54036200   c
            6048-6165           JAXUCZ010000008.1  54035231-54035348   c
            6166-6244           JAXUCZ010000008.1  54035039-54035117   c
            6245-6405           JAXUCZ010000008.1  54033984-54034144   c
            6406-6588           JAXUCZ010000008.1  54033404-54033586   c
            6589-10828          JAXUCZ010000008.1  54028999-54033238   c
            10829-10909         JAXUCZ010000008.1  54028222-54028302   c
            10910-10974         JAXUCZ010000008.1  54026544-54026608   c
            10975-11145         JAXUCZ010000008.1  54025053-54025223   c
            11146-11220         JAXUCZ010000008.1  54023014-54023088   c
            11221-11399         JAXUCZ010000008.1  54021039-54021217   c
            11400-11503         JAXUCZ010000008.1  54020774-54020877   c
            11504-11587         JAXUCZ010000008.1  54019887-54019970   c
            11588-11717         JAXUCZ010000008.1  54019278-54019407   c
            11718-16584         JAXUCZ010000008.1  54013547-54018413   c
FEATURES             Location/Qualifiers
     source          1..16584
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..16584
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /note="lysine methyltransferase 2A"
                     /db_xref="GeneID:315606"
                     /db_xref="RGD:1586165"
     exon            1..461
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..11993
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /EC_number="2.1.1.354"
                     /note="isoform 1 is encoded by transcript variant 1;
                     Mixed-lineage leukemia (also acute lymphocytic leukemia 1
                     or tritorax Drosophila gene); histone-lysine
                     N-methyltransferase MLL; lysine (K)-specific
                     methyltransferase 2A; histone-lysine N-methyltransferase
                     2A; myeloid/lymphoid or mixed-lineage leukemia 1;
                     myeloid/lymphoid or mixed-lineage leukemia (trithorax
                     homolog, Drosophila); Mixed-lineage leukemia (also acute
                     lymphocytic leukemia 1 or trithorax Drosophila gene)"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase 2A isoform 1"
                     /protein_id="NP_001101609.2"
                     /db_xref="GeneID:315606"
                     /db_xref="RGD:1586165"
                     /translation="MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGP
                     PAGGGGPGAPPSPPAVAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSASSGP
                     ALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRS
                     PTRSPSVKASPRKPRGRPRSGSDRNPAILSDPSVFSPLNKSETKSTDKIKKKDSKSIE
                     KKRGRPPTFPGVKIKITHGKDIAELTQGSKEDSLKKVKRTPSAMFQQATKIKKLRAGK
                     LSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKE
                     GTPPLTKEDKTVVRQSPRRIKPVRIIPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQ
                     LQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSRF
                     SATSCGSSEKSSAASQHSSQMSSDSSRSSSPSIDTTSDSQASEEIQALPEERSNTPEV
                     HTPLPISQSPENESNDRRGRRYSMSERSFGSRTTKKLPTLQSAPQQQTSSSPPPPLLT
                     PPPPLQPASGISDHTPWLMPPTIPLASPFLPASAAPMQGKRKSILREPTFRWTSLKHS
                     RSEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGSAASARLFSPLH
                     SGTRFDIHKRSPILRAPRFTPSEAHSRIFESVTLPSNRTSSGASSSGVSNRKRKRKVF
                     SPIRSEPRSPSHSMRTRSGRLSTSELSPLTPPSSVSSSLSIPVSPLAASALNPTFTFP
                     SHSLTQSGESTEKSQRARKQTSAPAEPFSSNSPALFPWFTPGSQTEKGRKKDTAPEEL
                     SKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSDIQSSSALYPVGRVSKEKV
                     AGEDVGTSSSAKKATGRKKSSSLDSGADIAPVTLGDTTAVKAKILIKKGRGNLEKNNL
                     DLGPTAPSLEKEKTLCLSTPSPSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKA
                     QLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDM
                     PTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKK
                     GRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYL
                     QKQTKAVKKKEKKSKATEKKESKESTVVKSSLESAQKAAPPVREEPAPKKSSSEPPPR
                     KPVEEKTEEGGAPAPAPAPAPAPAPAPAPAPAPAPAPEPKQASTPASRKSSKQVSQPA
                     AVVPPQPPSTALQKKEAPKAIPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPK
                     DKEKPPPVSKQENAGTLNILNPLLNGISSKQKIPADGVHRIRVDFKEDCEAENVWEMG
                     GLGILTSVPITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCC
                     RRCKFCHVCGRQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCK
                     SCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCD
                     RWVHSKCEGLSGTEDEMYEILSNLPESVAYTCVNCTERHPAEWRLALEKELQASLKQV
                     LTALLNSRTTSHLLRYRQAAKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDEQQP
                     LDLEGVKKKMDQGNYVSVLEFSDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQME
                     RVFPWFSVKKSRFWEPNKVSNNSGMLPNAVLPPSLDHNYAQWQEREESSHTEQPPLMK
                     KIIPAPKPKGPGEPDSPTPLHPPTPPILSTDRSREDSPELHPPPGIDDNRQCALCLMY
                     GDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQ
                     KPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDLIKGEVVPENGFEVFR
                     RVFVDFEGISLRRKFLNGLEPESVHVMIGSMTIDCLGILNDLSDCEDKLFPIGYQCSR
                     VYWSTTDARKRCVYTCKIMECRPPVVEPDINSTVEHDDNRTIAHSPSSFIEASCKDSQ
                     STAAILSPPSPDRPRSQASSSCYCHVISKVPRIRTPSYSPTQRSPGCRPLPSAGSPTP
                     TTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPLRSKLRIMSPVRSGSVYSRSSVSSVP
                     SLGTATDPESSAKATDRAGPLNSSANLGHSTPVSSGSQRTVVTGGSKTSHLDGSSSSG
                     VKRSSASDLAPKGSSLKGEKNRTPGSKSTDGSAHNTAYSGIPKLAPQVLNAAPGELNV
                     SKIGTFAEPSTVPFSKETVSYPQLHLRGQRSDRDQHMDSTQSVKPSPNEDGEIKTLKL
                     PGMGHRPSILHEHVGSSSRDRRQKGKKSSKETCKEKHSSKSFLEPGQVTTGEEGNLKP
                     EFADEVLTPGFLGQRPCNNVSSDKTGDKILPLSGVPKGQSTQVEGSSKELQAPRKCSV
                     KVTPLKMESENQSKNTQKESGPGSPAHMESACPAEPASASRSPGAGPGVQPSPNNTSS
                     QDPQSNNYQNLPEQDRNLMIPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVR
                     SYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGGDER
                     LASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATSRKSSQIPKRNGKENGTENLK
                     IDRPEDAGEKEHVIKSAVGHKNEPKLDNCHSVSRVKAQGQDSLEAQLSSLESSRRVHT
                     STPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESS
                     SSELLTLGEGLGLDSNREKDMGLFEVFSQQLPATEPVDSSVSSSISAEEQFELPLELP
                     SDLSVLTTRSPTVPSQNSSRLAVISDSGEKRVTITEKSVTSTEGDPALLSPGVDPAPE
                     GHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQ
                     KYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKI
                     QLTSPVSSTPNVMETNTSVLGPMGSGLTLTTGLNPSLPPSQSLFPPASKGLLSMPHHQ
                     HLHSFPAAAQSSFPPNISSPPSGLLIGVQPPPDPQLLGSEANQRTDLTTTVTTPSSGL
                     KKRPISRLHTRKNKKLAPSSAPSNIAPSDVVSNMTLINFTPSQLSNHPSLLDLGSLNP
                     SSHRTVPNIIKRSKSGIMYFEQAPLLPPQSVGGTTATGAGSSTISQDTSHLTSGPVSA
                     LASGSSVLNVVSMQTTTTPTSSTSVPGHVTLANQRLLGTPDIGSISHLLIKASHQSLG
                     IQDQPVALPQSSGMFPQLGTSQTPSAAAMTAASSICVLPSSQTAGMTAASPPREAEEQ
                     YKLQRVNQLLAGKTGTLSLQRDRDPDSAPGTQPSNFTQTAEAPNGVRLEQNKTLPSAK
                     QASSTSPGSSPSSGQQSGSSSVPGPTKPKPKVKRIQLPLDKGSGKKHKVSHLRTSSEA
                     HIPHREANPAPQPSVKRTPRADREQQEAAGVEQPSQKECGQPAGPATALPEIQATQNP
                     ANEQENAEPKAVEEEESSFSSPLMLWLQQEQKRKESITERKPKKGLVFEISSDDGFQI
                     CAESIEDAWKSLTDKVQEARSNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKH
                     CRNYKFRFHKPEEANEPPLNPHGSARAEVHLRQSAFDMFNFLASKHRQPPEYNPNDEE
                     EEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMV
                     IEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNC
                     YSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRKFLN"
     exon            462..531
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            532..3182
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            3183..3360
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            3361..3595
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            3596..3660
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            3661..4098
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4099..4172
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4173..4304
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4305..4418
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4419..4565
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4566..4661
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4662..4782
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4783..4905
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            4906..5090
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5091..5264
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5265..5375
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5376..5449
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5450..5643
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5644..5750
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5751..5888
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            5889..6047
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            6048..6165
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            6166..6244
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            6245..6405
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            6406..6588
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            6589..10828
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            10829..10909
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            10910..10974
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            10975..11145
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            11146..11220
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            11221..11399
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            11400..11503
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            11504..11587
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            11588..11717
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
     exon            11718..16584
                     /gene="Kmt2a"
                     /gene_synonym="Mll; Mll1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccctctcg ctgcttcact tacggggcga acatggcgca cagctgtcgg tggcgcttcc
       61 ccgcccgacc cgggaccacc gggggcggcg gcggcggggg gcgccggggc ctagggggcg
      121 ccccgcggca acgcgtcccg gccttgctgc ttccccccgg gcccccggcc ggcggtggcg
      181 gccccggggc gcccccctcc cccccggcgg tggcggcggc ggcggcggcg ggaagcagcg
      241 gggctggggt tccaggggga gcggccgccg cctcagcagc ctcttcgtcg tccgcctcgt
      301 cttcgtcttc gtcatcgtcc tcagcctcct cagggccggc cctgctccgg gtgggcccgg
      361 gcttcgacgc ggcgctgcag gtctcggccg ccatcggcac caacctgcgc cggttccggg
      421 cagtgtttgg ggagagcggc gggggaggcg gcagcggaga ggatgagcag ttcttaggtt
      481 ttggctcaga tgaagaagtc agagtgcgaa gccccaccag gtctccttca gttaaagcta
      541 gtcctcgaaa acctcgcggg agacctagaa gtggctctga ccgaaatcca gctatcctct
      601 cagacccatc tgtgttttcc cctctaaata aatcagagac caaatctaca gataaaatca
      661 agaagaagga ttctaagagc atagaaaaga agagaggaag acctcccacc ttccctgggg
      721 tgaagatcaa aatcacacat ggaaaggaca ttgcagagtt aacacaagga agcaaagagg
      781 acagcctgaa aaaagttaaa cggacccctt ctgctatgtt ccagcaagcc acaaagatta
      841 aaaagttaag agcaggtaaa ctgtctcctc tcaagtctaa gtttaagaca gggaagctcc
      901 agataggaag gaagggggta cagattgtaa gacggcgagg aaggcctcca tccacggaac
      961 ggataaagac cccttcaggc cttctcatta attctgaact ggaaaagcct cagaaggtcc
     1021 ggaaagacaa ggaaggaaca cccccactca caaaggaaga taagacagtt gtcagacaaa
     1081 gccctcgaag gattaagccg gtcaggatta ttccttcctc taaaaggaca gatgccacaa
     1141 ttgctaagca gctcctgcag agggccaaga agggggcgca gaagaaaatc gagaaggagg
     1201 cagcgcagct gcagggaagg aaggtgaaga cacaagtcaa gaatatccgg cagttcatca
     1261 tgcctgtggt cagtgccatc tcctcgagga tcatcaagac tccccgacgg ttcatagagg
     1321 atgaggatta tgatcctcca attaaaattg cacgactgga atctacaccc aacagtaggt
     1381 tcagcgccac atcctgcgga tcttccgaaa agtccagtgc agcttcccag cactcctctc
     1441 agatgtcttc agactcctcc cgatctagca gtcccagtat cgataccacc tcagattccc
     1501 aggcctccga agagatccag gcacttcccg aggagcggag taataccccc gaagttcata
     1561 ccccactgcc tatttcccag tccccagaaa atgaaagtaa tgacaggaga ggcagacggt
     1621 attcgatgtc tgagagaagc tttggatcta gaacaactaa aaaattacca actctacaaa
     1681 gtgccccaca gcagcagacc tcctcctcgc cacctccacc tctgcttact cctccccctc
     1741 cactgcagcc agcctccggc atctctgacc acacgccttg gctcatgcct cccaccatcc
     1801 ccttagcatc accattcctg cctgcttctg ctgctcccat gcaagggaag cggaaatcta
     1861 ttttgcggga gccaacattt aggtggactt ctttaaagca ttcgaggtca gagccacagt
     1921 acttttcctc agcaaagtat gccaaagaag gtctgattcg caaaccaata tttgataact
     1981 tccgaccccc tccactgact cccgaggatg tcggcttcgc ttctggtttt tctgcatctg
     2041 gttctgcagc ttcggcccgg ttgttctcac cactccattc tggaacaagg tttgatattc
     2101 ataagaggag ccccattctg agagctccca gatttactcc aagtgaggca cactctagaa
     2161 tatttgagtc tgtgaccttg cctagtaatc gaacttcttc tggagcgtcc tcttcgggag
     2221 tatctaatag aaaaaggaaa aggaaagtgt ttagtccgat tcggtctgaa ccaagatcac
     2281 cttctcactc catgaggaca agaagcggaa ggcttagcac ctctgagctg tcacctctca
     2341 ctcccccgtc ttctgtctcc tcctcattaa gcattcccgt tagtcctctt gccgctagtg
     2401 ccttaaaccc aacttttact tttccttctc actccctaac tcagtctggg gaatctacag
     2461 agaaaagtca gagagcaagg aagcagacta gtgctccggc agagccgttt tcatcaaaca
     2521 gccctgctct cttcccgtgg ttcaccccag gctctcagac cgagaagggg agaaagaaag
     2581 acacagcccc ggaggagctg tccaaagatc gcgatgctga caagagcgtg gagaaggaca
     2641 agagtagaga gagagaccgg gagagagaga aggagaataa gcgggagtca aggaaagaga
     2701 aaaggaaaaa gggctcagac attcagagta gctctgcttt gtatcctgtg ggtcgggttt
     2761 ccaaagagaa ggttgctgga gaagatgttg gcacttcatc ttctgccaaa aaagcaacag
     2821 ggcggaagaa gtcttcatca cttgattctg gggctgatat tgctcctgtg actcttgggg
     2881 acacaacagc tgtcaaagcc aaaattctta taaagaaagg gagaggaaat ctggaaaaaa
     2941 acaacttgga tctcggccca actgccccat ccctggagaa ggagaaaacc ctctgccttt
     3001 ccactccttc acctagcact gttaaacatt ccacttcctc cataggctcc atgttggctc
     3061 aggcagacaa gcttccaatg actgacaaga gggttgccag cctcctaaaa aaggccaaag
     3121 cccagctctg caagatagag aagagtaaga gtctcaaaca gactgaccag cccaaagcac
     3181 agggtcaaga aagtgattct tcagaaacct ctgtgcgagg accccggatc aaacatgtct
     3241 gcagaagagc tgctgtcgcc cttggccgca agcgagctgt gtttcctgac gacatgccca
     3301 ccttgagtgc cttaccgtgg gaagaacgag aaaaaatttt gtcttccatg gggaatgatg
     3361 acaagtcatc aattgctggc tcagaagatg ctgaacccct tgctccaccc atcaaaccga
     3421 ttaagcctgt caccagaaac aaggcgccgc aggagcctcc ggtgaagaag gggcggcggt
     3481 cgaggcggtg tggacagtgc cctggctgcc aggtgcctga ggactgtggc gtctgtacta
     3541 attgcttgga caagcccaag ttcggtggcc gcaacataaa gaagcaatgc tgcaagatga
     3601 gaaaatgtca gaatctgcag tggatgcctt ccaaagccta ccttcagaag cagactaaag
     3661 ctgtgaaaaa gaaagagaaa aagtctaagg ccactgagaa gaaagaaagc aaagagagca
     3721 ctgttgtgaa gagctccttg gagtctgctc agaaggctgc cccgccagtg cgggaggagc
     3781 ctgccccaaa gaagagcagc agtgagcctc caccccgaaa gcctgtggaa gaaaagactg
     3841 aagaaggggg tgcccctgcg cctgcgcctg cgcctgcgcc tgcacctgca cctgcacctg
     3901 cacctgcacc tgcacctgca cctgcacctg aacccaaaca ggccagcact ccagcatccc
     3961 ggaagtccag caagcaagtc tcccagccag cagcagtcgt cccccctcag cctccaagca
     4021 cagcactgca gaaaaaagaa gctcccaagg ccattccaag tgagcccaag aagaagcagc
     4081 ctccaccccc agaatcaggg ccagagcaaa gcaagcagaa aaaagtggcc ccccgcccaa
     4141 gtatccctgt aaaacaaaaa ccaaaggaca aggagaagcc acctccagta agtaagcaag
     4201 agaatgcagg cactttgaac atcctcaacc cactcttgaa tggcatcagt tccaagcaga
     4261 aaatcccagc agatggagtc cacaggatca gagtggactt taaggaagac tgtgaagcag
     4321 aaaatgtgtg ggagatggga ggcttaggga tcctgacctc tgttcccata acacccagag
     4381 tagtgtgctt tctctgtgcc agtagtgggc atgtagagtt tgtgtattgc caagtgtgtt
     4441 gtgaaccctt ccacaagttt tgcttagagg agaatgagcg ccctctggag gaccagctgg
     4501 aaaactggtg ttgtcgccgc tgcaagttct gccacgtctg tggaaggcag catcaggcta
     4561 caaagcagct gctggaatgt aacaagtgcc gaaacagcta tcaccccgag tgcctgggac
     4621 caaactaccc caccaagccc acgaagaaga agaaagtgtg gatctgcacc aagtgtgtcc
     4681 gctgcaagag ctgtggatcc acgactccag gcaaagggtg ggacgcacag tggtctcacg
     4741 atttttcact gtgccatgat tgtgccaaac tctttgctaa agggaacttc tgccctctct
     4801 gtgacaagtg ctacgacgac gatgactacg agagcaagat gatgcagtgt gggaagtgcg
     4861 accggtgggt ccactccaag tgcgagggtc tctcaggtac agaagacgag atgtatgaga
     4921 ttctgtctaa cctgccggaa agcgtggctt acacgtgtgt gaactgcact gagcgccacc
     4981 ctgcagagtg gagactggcc ctggagaaag agctgcaggc gtccctcaag caggttctca
     5041 cagccctgtt gaattcccgg actaccagtc acttgctgcg gtaccgccag gctgccaagc
     5101 ctccagactt aaaccctgag accgaggaga gcataccttc ccggagctcc ccagaagggc
     5161 cagatcctcc tgtccttact gaggtcagca aacaggatga acagcagccg ttagacctcg
     5221 agggagtcaa gaagaaaatg gaccagggca actacgtatc tgtgttggag ttcagcgacg
     5281 atattgtgaa gatcattcag gcagccatta attctgatgg agggcagcca gagataaaaa
     5341 aagccaacag catggtcaag tctttcttta ttcggcaaat ggagcgcgtt tttccgtggt
     5401 tcagtgtcaa aaagtccaga ttttgggagc caaataaagt atcaaacaac agtgggatgt
     5461 tacccaacgc agtgctacca ccttcacttg accataacta tgctcagtgg caggagcgag
     5521 aggagagcag ccacaccgag cagcctcctc taatgaagaa aatcattcca gctcccaaac
     5581 ccaaaggacc cggagagccg gactcgccca cgccgctcca tcctcctaca cccccaatct
     5641 tgagtactga caggagtcga gaagacagtc cagaactgca tccaccccca ggcatagatg
     5701 acaaccgaca gtgtgcgctg tgtctgatgt atggtgatga tagtgctaac gatgctggcc
     5761 gtttgctgta tattggccaa aatgagtgga cacatgtgaa ctgtgctttg tggtcagcag
     5821 aggtgtttga agatgatgac ggctcactaa agaacgtgca tatggctgtg attaggggca
     5881 agcagctgag atgtgaattc tgccagaagc caggagccac cgtgggttgc tgcctcacat
     5941 cctgcaccag caactaccat ttcatgtgtt cccgtgccaa gaactgtgtc tttctggacg
     6001 ataaaaaagt gtactgtcag cggcatcggg atttgatcaa aggcgaggtg gtccctgaga
     6061 atggatttga agtcttcaga agagtgtttg tagacttcga aggaatcagc ttgcgcagga
     6121 agttcctcaa tggcttggaa ccagaaagcg tccacgtgat gataggctca atgacgatcg
     6181 actgtttggg gattctgaat gacctctctg actgtgagga taaactcttt cctattggat
     6241 accagtgttc tcgggtatac tggagcacca cagatgcccg caagcgctgc gtgtacacat
     6301 gcaagatcat ggagtgccgt ccacctgtcg tagagccaga tatcaatagc acggttgagc
     6361 atgatgacaa taggaccatt gcccatagcc catcatcatt tatagaagct tcatgtaagg
     6421 acagtcagag cacagctgca attctcagtc ctccgtcacc agaccggcct cgttcacagg
     6481 cctcaagctc ctgctattgc catgtcatct caaaggtccc taggattcga acacccagct
     6541 actcccctac acagaggtcc cctggctgcc gcccattgcc ttctgcagga agtcctaccc
     6601 caaccactca cgaaattgtc acagtcggtg accctttact gtcctctggt cttcggagca
     6661 ttggctctag gcgtcacagt acttcttcct tgtcacccct gcggtccaag ctccggataa
     6721 tgtctccagt gagaagtggg agtgtttact ccaggagtag tgtttcctca gtccccagcc
     6781 ttgggactgc tacagatccc gagtccagtg ccaaagcaac ggatcgcgca gggccgctga
     6841 attcaagtgc taatctaggg cacagcactc ccgtctcttc aggctcacag aggacagtgg
     6901 tcactggagg ctccaaaact agtcatctgg atgggtcgtc atcctcaggt gtgaagcggt
     6961 ctagtgcttc agacttggca cccaaaggct cctcgttaaa gggagagaaa aacagaactc
     7021 caggttccaa gagcacagat ggatctgcac ataacacagc ttactctgga attcctaaac
     7081 tggcaccaca ggttcttaat gcggctcctg gggaattaaa cgttagcaaa attggcactt
     7141 ttgccgaacc ctctacagtg ccattttcta aagaaacagt ctcctaccca caactccact
     7201 taaggggaca aagaagtgac agagaccagc acatggattc tacccagtca gtaaaaccct
     7261 ctccaaatga agatggcgaa atcaaaacct tgaagctccc tggtatgggc cacaggccat
     7321 ccattctgca cgaacatgta gggtctagtt ccagagacag gagacagaaa gggaaaaagt
     7381 cttctaaaga gacttgcaaa gaaaagcatt ccagtaaatc ctttttggaa cctggtcagg
     7441 tgacaactgg tgaggaagga aacctaaagc cagagtttgc tgatgaggtg ttgactcctg
     7501 ggtttcttgg gcaacggcca tgtaataatg tttcatctga taagactggg gataaaatcc
     7561 ttcctctttc aggagtccct aaaggtcaat ccacacaagt ggaaggatct tccaaggagt
     7621 tacaggcacc ccggaagtgc tcagtcaaag tgacacctct gaaaatggaa agtgagaatc
     7681 agtccaaaaa cacccagaaa gaaagcggcc ctggttcccc tgcacacatg gagtcagcgt
     7741 gtccagcaga gccagcctca gcttccagaa gtccgggagc tggcccaggg gttcagccaa
     7801 gccccaacaa tacctcatcc caagatcctc aaagcaacaa ctatcagaat cttccagaac
     7861 aggacagaaa cctgatgatt ccagatggcc ccaagcctca ggaggatggc tctttcaaaa
     7921 ggcggtaccc ccgccgcagc gcgcgtgccc ggtctaacat gttctttggg ctcaccccgc
     7981 tttatggagt ccggtcttac ggtgaagaag acattccgtt ctacagcagt tccaccggga
     8041 agaagcgagg aaagagatca gcagaaggcc aggtagatgg ggccgatgac ttgagcactt
     8101 cggatgaaga cgacttatac tattacaact tcaccaggac agtgatttct tctggtgggg
     8161 acgagcgtct ggcatcccat aatttatttc gggaggagga acaatgcgat cttccaaaaa
     8221 tttcacagct ggatggtgtg gatgacggga cagagagtga caccagtgtc actgccacaa
     8281 gcaggaaaag cagccagatt ccaaagagaa atgggaaaga aaatggaacc gaaaatttaa
     8341 agatcgatcg gcccgaagat gctggcgaga aagagcatgt cattaagagt gctgttggcc
     8401 acaaaaacga gccaaagctg gataactgcc actctgtgag cagagtgaaa gcgcagggcc
     8461 aggattccct ggaagctcag ctcagctccc tggagtcgag ccgcagggtc cacacaagta
     8521 ccccctcaga caaaaactta ctggacacct acaacaccga gctcctgaag tcagactctg
     8581 acaataacaa cagtgacgac tgtggaaaca tcctgccttc agacatcatg gactttgtac
     8641 taaagaatac tccgtctatg caggctctgg gtgagagccc ggagtcctct tcctctgagc
     8701 tcttgactct tggtgaagga ctgggtctcg acagtaatcg ggaaaaggat atgggtcttt
     8761 ttgaagtgtt ctctcagcag ctgccagcaa cagagcctgt ggacagtagt gtctcctcct
     8821 ccatctcagc agaggagcag tttgagctgc ctcttgagct gccatctgac ctctctgtcc
     8881 tgaccacccg cagtcccacc gtccccagcc agaattccag tagactggcc gtaatctcgg
     8941 attcagggga gaagcgagtg accatcacag aaaagtcagt cacctctacc gagggcgacc
     9001 cagccctact gagtccagga gtagaccctg ctcctgaagg ccacatgact cctgaccact
     9061 tcatccaagg acacatggat gctgaccata tctccagccc tccctgtgga tcagtggaac
     9121 aaggtcatgg caacaaccag gatttaacta gaaacagtag cactcctggc cttcaggtac
     9181 ctgtttcccc cactgttccc atccagaacc agaagtatgt gcccaattct actgatagcc
     9241 ccggcccatc tcagatctct aatgcagctg tccaaaccac tccaccccac ctgaaaccag
     9301 ccactgagaa acttattgtt gttaatcaga acatgcagcc gctttatgtt ctccagactc
     9361 ttccaaatgg agtgacccaa aaaatccagt tgacctctcc tgttagttct acacccaatg
     9421 tgatggagac aaatacctcg gtattggggc ccatgggaag tgggctcacc ctaaccacag
     9481 gactaaatcc aagcttgcca ccttctcagt ctctgttccc tcctgctagc aaaggactgc
     9541 tctccatgcc tcatcaccag cacctacatt ccttccctgc agctgctcag agtagcttcc
     9601 cacccaatat cagcagtcct ccttcaggcc tacttattgg ggttcagcct cctccagatc
     9661 cccagctttt gggttcagaa gccaaccaga ggacagacct tactactaca gtgaccactc
     9721 catcctctgg actcaagaaa agacccatat ctcgtctgca cactcgaaag aataaaaaac
     9781 ttgctccctc tagtgcccct tcaaatattg ccccttctga tgtggtttct aacatgacac
     9841 tgattaactt cacaccctcc cagctttcaa accaccccag tctgttagac ttggggtcac
     9901 ttaacccttc atctcaccga actgtcccca acatcattaa aagatctaaa tctggcatca
     9961 tgtattttga acaggcaccc ctgttacccc cacagagtgt gggtggaacc actgccacag
    10021 gggcgggctc atcaacgata agccaagata ctagccacct cacgtctggg cctgtgtctg
    10081 ccttggcatc cggttcgtcc gtcctgaatg tggtgtccat gcaaactaca acaaccccta
    10141 caagtagcac atcagttcca ggacatgtca ccttagccaa ccagaggttg cttgggaccc
    10201 cagatattgg ctcaataagt catcttctaa tcaaagccag ccaccagagc ctgggcattc
    10261 aggaccagcc tgtggcttta ccacaaagtt caggaatgtt cccccagctg gggacctcac
    10321 agactccctc tgctgctgca atgacagcag catctagtat ctgcgtgctc ccctcttctc
    10381 agactgcagg catgacagct gcatcccctc ccagggaggc tgaagaacag tataagctac
    10441 agcgagtaaa ccagctccta gctggcaaaa ctggtaccct gtctttgcag cgggatcggg
    10501 atcctgattc tgctccgggg acccagccat ccaacttcac ccagacagca gaagctccta
    10561 acggtgtgag gctagagcag aacaagactt taccctcagc taagcaagcc agctccacct
    10621 ctccagggag ttccccatcc tctggacagc agtcaggaag ttcctcagtg ccaggtccca
    10681 ctaaaccaaa accaaaagtc aaacggattc agctgcccct agacaagggg agtggcaaga
    10741 agcacaaagt ttcccatttg cggaccagtt ctgaagcaca cattccacac cgagaagcca
    10801 acccagcgcc ccagccctca gttaagcgga ctcctagggc ggacagggag cagcaggaag
    10861 cagctggagt ggaacagcca tcacagaagg agtgtgggca gcctgcagga ccagcgactg
    10921 ctctcccaga gatccaggca acacagaatc cagcaaatga gcaagaaaac gcagaaccaa
    10981 aagcagtgga agaagaagag agcagtttca gctctcctct gatgctttgg ctccagcaag
    11041 aacaaaagag gaaggaaagc attactgaga ggaagcccaa gaaaggactg gtttttgaga
    11101 tttcgagtga tgacggcttt cagatctgtg cggaaagtat cgaagatgcc tggaagtcac
    11161 tgacagataa agtccaggaa gcacggtcaa atgcccgcct gaagcaactc tcattcgcag
    11221 gtgtgaacgg tttgaggatg ctggggattc tccacgatgc ggtggtgttt ctgattgagc
    11281 agctgtctgg tgccaagcac tgtcggaatt acaaattccg tttccacaaa ccagaagagg
    11341 ccaatgaacc ccccttgaac cctcacggct cagccagggc tgaggtccac ctgaggcaat
    11401 cagcatttga catgtttaac ttcctggctt ctaaacatcg acagccccct gagtacaacc
    11461 ctaatgacga ggaagaggaa gaggtgcagc tgaagtccgc acggagggca acaagcatgg
    11521 atctcccgat gcccatgcgg ttccggcact taaaaaagac gtctaaggag gcggttggtg
    11581 tctacaggtc tcccatccac ggtcggggtc ttttctgtaa gagaaacatt gatgcaggag
    11641 agatggtgat tgagtacgcc ggcaacgtca tccgctccat ccagacggac aagcgtgaga
    11701 agtactatga cagcaagggc attggttgct acatgttccg aattgatgac tcggaggtag
    11761 tggatgccac catgcatgga aatgcggcac gcttcatcaa tcactcttgt gagcctaact
    11821 gctactcccg ggtcatcaat attgatgggc agaagcacat tgtcatcttc gctatgcgta
    11881 agatctaccg gggggaggag ctcacctatg actataagtt ccctattgag gacgccagca
    11941 acaagctacc ctgcaactgt ggcgccaaaa aatgccggaa gttcctgaac taaagctgct
    12001 catcttcctg tgatggagta ccaggacccc gggccaccta aagccatgct gaaggacatc
    12061 ccagcactcc agagctccaa ggattgagcg ggcagtcgag ggtcctctgg ctgagcaccc
    12121 tagtgtccac atgcacatca tgtgatcata gtcttggaga gagaagggtc tcaaagagaa
    12181 aagtccccag atggctttct cccggggcct ctctgattgt cgaaagacct gggaaactgg
    12241 gtcctgggag atttgcctgc agggagcatg cagagggttc cttacagtgg gcgatggggt
    12301 ctgagcatgt cctcagagag cagtttgtca tcctcatctt agccctctcc caagccctaa
    12361 gagcgacggg tcggacaaga ccccagatac agggttggtg ggatccctgg tagtttgcca
    12421 gttaggccag gcctgtggcc atctggtggt tttccctact atctgcccac ttaagagttc
    12481 gctttggttg ggagacaggt ttcctagcac ctctggtgtc aaaggctgtc ttggggttgt
    12541 gccaattaat taccaaacat tgagcctgtg gctataagtg ggagcgttgc cctgtgagcc
    12601 ttaccgtagc cagtgacctt tcttgatgat aggagcggct tcctctccat tccttctctt
    12661 tattcccttc tcccctcctc catccttcat ctgctgcttt cccattcttc tttctgggta
    12721 gcgggagctc acctccctgc tcgaggacac tcctactcgg tataggaagt gcctacagag
    12781 agtcccctcg cctgtaagcc ctccaggtgg ggaagtgggc aggagccatt ggccatagcc
    12841 agatggagtt tggagatctc ataaagctcc attgagagtt ttaaagagac atatgtagca
    12901 aggttttttt tttaacaaga ggctagagaa tatttaaata ggatacaaca gcagagtaca
    12961 gtagccagga taaacgccgg cccttcctgg gacatgctta cttcctttcc ccttctgaag
    13021 acataggaag atgaatttct aaaaggtcag tgtccagccg aaagaacact aatcagattt
    13081 caaggcccca aacttggggg acccgaccac actgctgagg gacctctgcc acctgtgtgc
    13141 agcccgtggc tgagcaaagt taatgacact actgccctga ttactcctta ggatgtggat
    13201 aaccagcagc aaatgtttct ttcttccccc aagacaatgt cttgagcctg ttaaattaag
    13261 tcattggatt ttcctctgtt ctgtttacag tttactattt aaggttttat aaatgtaaat
    13321 atattttgta tatttttcta tgcgaagcac ttcataggga gaagcactta tgacaaggct
    13381 attttttaaa ccgtggtatt atcctaattt aaaagaagat cggtttttaa tgacttttta
    13441 ttttcatagg atgaagttag agaaaatatt cagctgtcca cacaaagtct ggtttttcct
    13501 gcccagcttc cccctggaaa gtgtactttt tgttgttcca tgtgtagctc gtttgtaccc
    13561 attgacataa atgttccttg ggtctgctct ttatagtaat tgagaaggaa ggtcacccgc
    13621 tccattaggc cactgccctc catggccaag ggatgagggt acagaaccct ggcccaccaa
    13681 ttcctcctct ttgctgcatt gcccctctcc ctctgggtcg gctccagagt gcgagcagca
    13741 ggctccattc gctccccttt ctctctctga gttagcaacc aagaagctgc aacttgatct
    13801 ttgccatctc tatctgcctc atagaccaac catctccttt ccttctctgc ccaccaagtc
    13861 cttgtacctg caaagaaccc actgaccgcc tcctgccctc tcggaggcag cctgttgaac
    13921 ctgaagcaca gtatgaccac tcacgatcaa gcagatctct gcacctgcca caaggtttca
    13981 gggtagcgta gtccaggtgg agggcagggc accctttctc ttatggaagt cagcaaagca
    14041 atatgatgca gcccagaact ctgccaggac tcgtggctct gctgtgcctt ccattctggg
    14101 ctccctttcc ttccgtgacc ttaagaactt tgtctggtgg ctttgctgga acatcgtcac
    14161 tgtttccact gtgggaagcc cagcactgtg gccaggatgg cagagagtcc cttgtcatca
    14221 tggagaagtg ccagcagggg actggggaaa agcactctac ccagacctca cctcccaccc
    14281 tccttttgcc catgaacaag atgctgtggc ccaaggggtt ccactagtgt ctggtttcct
    14341 ttcttattgc actgtgtgag gtttttttgt aaatccttgt attcctattt ttttttatga
    14401 aaaaaaatgt aagctgcatt tgttactgaa ttgattaatg cactgatggg tcatgcgttc
    14461 atcttgagag agacccaaag gccagtcaga gggtgggggg aactcagcta acagacctag
    14521 ttactgccct gctaggccat gctgtactgt gagccccctc ctcatcctct ttctacaacc
    14581 ccaatccctg aggatggggg gaacccacct ttcctcctcc tccagctggt ttgccttgcc
    14641 cgcccaccca ctgtcaacca cagagatgag aaattcctct ttcagctcag ccttgagtcc
    14701 attgccaaaa ttcagcatac ctgccagcaa cttgggggat aagccagagt atccccacaa
    14761 gcgggagaga aggcaacaaa acagaaggca cagctgtctc caaaacacat ctgctttgtt
    14821 ttgaaagtga ccaggagaac ctctgcacag aagtgcaggt tgaggacttt gcgctgggtc
    14881 attcccaaga atcccccaag gggcaaccca cagccccagg agtgacagct gcggacctcg
    14941 taggttcttg gagagccgac tcacctcggc ttcgctgcta gaacctgttg tggctgcatt
    15001 tcctggtggc caacgacaac tgtgtaacca gaatagctgc atggcactga ccctttggtc
    15061 ggaacttggt ccctgggctc cttcattgct gcccactatg tccagcacaa cccctccctg
    15121 tttttaaacc aatcgcaact aaggaggaaa ccctggcact tcttaggttt tcaacccaaa
    15181 ctcctttgcc aggacccagc tcacctctgt catcccccgg ccaatccaat aggcaccgtg
    15241 cagcaacctc gatttagaaa aagaaaaaag aaaaaaaaag aagaaaaaaa actaaaaata
    15301 attttaaaaa aatatacaac acacatacaa gaaaaatctc ttaatgaatg tatctttcta
    15361 aaggactgac tgatgctcaa tcaaatacct gaaaatacta gaggtcacag cctcagatgt
    15421 taacttttat tggatttggg attctttttc atagaaacca agttgttttt tgttgttgtt
    15481 gttgttgttg ttgttattgt tgttgttgtt ttttaaggaa aagcgggtca ttgcaaaggg
    15541 ctgggtgtaa ttttacgttt cctttccttc gttttaaagc aatacaaagt tactgagcag
    15601 atagttttgt gccgaatcat gaataccagt caagtctcac actctgaaaa cttgcggacc
    15661 ttttcgtttg tttgtttgtt ttggttttca aataaatata aatatatata tatataggaa
    15721 ctaatatagg aatgcaccat tgtaatgaag cctagttcag tccacggctt ttacttctct
    15781 taacactata gataaggatc gtgtgacagt cgctagtcaa ggcagggaag tgtcaggctc
    15841 cggtgacgct ggcaccgcac ttggatacca ggcgcccacg cagagcagag ctggtgtcac
    15901 ctgggttctt cctgcctgtg aatgttgcca gtcggtacct gtactcctct ctacttttgg
    15961 ttatgaatgt tggggtcacc acctgcattt aggggaaaat tgtgttctgt gctttctggt
    16021 atcttgttcc aaggtacact agttctgtct ttcaaccaag aaaaaaaaaa tagacttgtg
    16081 gtgttttttt tttttgtttg ttttgttttt tgttttcttg aactttaacg gtctccttag
    16141 caaatacagg tagttgagta attgtttcac gagctgaaca gtgacaagct tcatttctag
    16201 aataagacat ttctctacag ctgtgtcatg tacaatggat cttctgggtt tttttttttt
    16261 tctttcgttt gttttgttct gcttcccttt ttttccttgt gttcttccaa gcttctggtt
    16321 agagacaaaa tggggtgggg ggaaggaaaa tatgtctaaa gtccatcagt gttaactccc
    16381 tgagacaggg atgaaggaaa atactttaat agttcaaaaa aaaaaataat gctgaaagct
    16441 ctctacgaaa gactgaatgt aaaagtaaaa agtgtacata attgtaaaaa caaaaaagga
    16501 gtttttaaac atgtttattt tctatgcact tttttttatt taagtgatag tttaattaat
    16561 aaacatgtca agtttattgc tgtg
//
