LOCUS       XM_039091047            2299 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus kynurenine 3-monooxygenase (Kmo),
            transcript variant X8, mRNA.
ACCESSION   XM_039091047
VERSION     XM_039091047.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039091047.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2299
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2299
                     /gene="Kmo"
                     /note="kynurenine 3-monooxygenase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     ESTs, and 100% coverage of the annotated genomic feature
                     by RNAseq alignments, including 11 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:59113"
                     /db_xref="RGD:620610"
     CDS             87..977
                     /gene="Kmo"
                     /codon_start=1
                     /product="kynurenine 3-monooxygenase isoform X6"
                     /protein_id="XP_038946975.1"
                     /db_xref="GeneID:59113"
                     /db_xref="RGD:620610"
                     /translation="MEPNCLHIWPRNAFMMIALPNMDKSFTCTLFMSFEEFEKLPTHS
                     DVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPMISVKCSPFHLKSRCVLMGDAAHAI
                     VPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLPEFSRFRIPDDHAISDLSMYNYIEM
                     RAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMVAFTRIRYHEAVLRWHWQKKIKPVS
                     SLQTVEHALYLWGWGSKENLVINRGLFVLGSLVAIGSAYILVHHLSPRPLELLRSAWT
                     GTSGHWNRSADISPRVPWSH"
ORIGIN      
        1 tatccctcat ggctatatgg agctgacaat tccacctaag aacggggagg tataatagtc
       61 aatctacaca agcactaagg tatgccatgg aacctaactg tcttcacatt tggcctagaa
      121 atgcctttat gatgatcgcc ctaccgaaca tggacaaatc tttcacatgc accttgttca
      181 tgtcctttga ggagtttgaa aagcttccaa cgcatagtga tgtgctggac ttcttccaga
      241 agaactttcc agatgccatc cctctgatgg gcgagcaagc cctcatgaga gatttctttc
      301 tgttgcctgc ccagcccatg atatcagtaa agtgctctcc cttccacctg aagtcacgct
      361 gtgtgctgat gggagatgca gctcatgcca tcgtcccatt ttttgggcaa ggaatgaatg
      421 cgggctttga agactgcttg gtatttgatg agttaatgga caaattcaat aatgatctta
      481 gtgtgtgcct tcctgaattc tcaagattta ggattcctga tgaccatgca atttcagacc
      541 tgtctatgta caattacata gagatgcgag cgcatgtcaa ctctaggtgg ttcctgtttc
      601 aaaggctcct ggataaattt cttcatgcac taatgccatc cactttcatc cctctctata
      661 ccatggtcgc cttcaccaga ataagatacc acgaggcagt gctgcgctgg cattggcaaa
      721 aaaagataaa acctgtctcg agtctacaga ctgtggaaca tgcactctac ctatgggggt
      781 ggggaagcaa agagaacttg gtgataaaca gaggactctt tgtccttggg tccctggtag
      841 ccattggaag tgcctacata ctcgtgcacc acctgtcccc gagacctctg gaactcctga
      901 gatctgcctg gacgggaacc tctggccact ggaataggag tgcagacatt tctccacgag
      961 ttccatggag tcactaggac aaatgcccca gttcactatc catagtgtca acgttccggg
     1021 tagcaaatgc ttgattcctc ttcaatatca agggagaaac tcatgttccc attgccgtct
     1081 tcagttcact atgggaaaat cattgtcagc atataattaa gttcggagtg gagggctgtt
     1141 tttacagtgt ctcattattt tgcatgcttg gactgggttc aatttttaaa tttaaaaaca
     1201 caataaccaa agtctctttc acttctcaaa aaaatttttt ttcctataga ggacaataca
     1261 ggatcaaaaa caccaggact gaaaaccaca gcttgcctgg tgctaattcc tctttatagc
     1321 agtggtgggg tttgctagtt catagccact tgctaaaggt agaggtgtga atgttccaaa
     1381 cagggtgttc caaagagttc caggataaat ctgttaaatt atttcccagt ccccagacct
     1441 cagaattatt actgttttga agataaggaa agggctatta atggcatctt aagtgaagga
     1501 taagaaaggg ttgttagtag taatacattt ataccagggt ggagaggaga tgggagggtg
     1561 ttttctagaa gcatagagac gcacagttca ttgcatttca gacatgcaga agtgattcgt
     1621 tgactgtccc acagacagaa tcggaagtta acttcatcat cagagactgg gacacttaga
     1681 aattcttttc attgtcaatt ttgagagcta caataatagt tatctaggaa atccaaaact
     1741 gaggttataa agataaaaca atttggcatt ttccataatg ccaaaagcat cctcgagtct
     1801 taacagtcta tgtttgaggt gtagggaaag aaaaatcatt cttttcctgg taagggatgt
     1861 agctcagtgg ggagtgtagc atgggtagag cccagggtta gattcaccag cactgcaaaa
     1921 ataaacagaa caatagttta ggagcatgca tgtatatttc atatggacat gggaaacgct
     1981 cagaaatgag ctgacttagg ggctagggag atggctcagc tgttaagtat gtgtgccact
     2041 cctgaagagg ctcctagttc cgtccccagc acccatttca ggcagcccag ttggaactcc
     2101 agctccagga gatccaaccc ctctggcttc cttgggcccc tgcacccatg tgcatataac
     2161 cacacatggc tccacaaggg aattaaaagt ctttaacaat cataatttct ggaagaggca
     2221 agggggtgta tgggaggagt tagacggaaa aaaagtaagg gaggaaatga tgcaatttaa
     2281 agttaaacaa aagaatagt
//
