LOCUS       XM_006250327            2827 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus kynurenine 3-monooxygenase (Kmo),
            transcript variant X3, mRNA.
ACCESSION   XM_006250327
VERSION     XM_006250327.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006250327.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006250327.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2827
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2827
                     /gene="Kmo"
                     /note="kynurenine 3-monooxygenase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 11
                     ESTs, and 99% coverage of the annotated genomic feature by
                     RNAseq alignments, including 12 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:59113"
                     /db_xref="RGD:620610"
     CDS             195..1505
                     /gene="Kmo"
                     /codon_start=1
                     /product="kynurenine 3-monooxygenase isoform X2"
                     /protein_id="XP_006250389.1"
                     /db_xref="GeneID:59113"
                     /db_xref="RGD:620610"
                     /translation="MCTKLGKIVSKGVPMKARMIHSLSGKKSAIPYGNKSQYILSISR
                     EKLNKDLLTAVESYPNAKVHFGHKLSKCCPEEGILTMLGPNKVPRDITCDLIVGCDGA
                     YSTVRAHLMKKPRFDYSQQYIPHGYMELTIPPKNGEYAMEPNCLHIWPRNAFMMIALP
                     NMDKSFTCTLFMSFEEFEKLPTHSDVLDFFQKNFPDAIPLMGEQALMRDFFLLPAQPM
                     ISVKCSPFHLKSRCVLMGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFNNDLSVCLP
                     EFSRFRIPDDHAISDLSMYNYIEMRAHVNSRWFLFQRLLDKFLHALMPSTFIPLYTMV
                     AFTRIRYHEAVLRWHWQKKIKPVSSLQTVEHALYLWGWGSKENLVINRGLFVLGSLVA
                     IGSAYILVHHLSPRPLELLRSAWTGTSGHWNRSADISPRVPWSH"
ORIGIN      
        1 aaaggctctg ggcttctggc aataaaaaga tcacaaaaca tcagcatgta gtgcagagag
       61 ttcctacctg agcagaggta ttctggcagc aatggcatcg tcggacactg aaggaaaaag
      121 agtggttgtt atcggtggtg gtttggttgg agcattgaac gcgtgctttc tcgcaaagag
      181 gaatttccaa gttgatgtgt acgaagctag ggaagatcgt gtccaaaggt gtgcccatga
      241 aagccagaat gatccactct ctctcgggaa agaagtctgc aattccctat gggaacaagt
      301 cacagtatat cctttcaata agcagagaaa agttaaacaa ggatctgctg actgccgtgg
      361 agtcctaccc caatgcaaag gtgcactttg gccacaagct gtcaaaatgc tgtccggagg
      421 aagggatact cacgatgctt ggacccaaca aagttcccag agacatcacg tgtgacctca
      481 ttgtaggatg tgatggggcc tactcaactg tcagagctca cctcatgaag aagccccgtt
      541 ttgattacag tcagcaatat atccctcatg gctatatgga gctgacaatt ccacctaaga
      601 acggggagta tgccatggaa cctaactgtc ttcacatttg gcctagaaat gcctttatga
      661 tgatcgccct accgaacatg gacaaatctt tcacatgcac cttgttcatg tcctttgagg
      721 agtttgaaaa gcttccaacg catagtgatg tgctggactt cttccagaag aactttccag
      781 atgccatccc tctgatgggc gagcaagccc tcatgagaga tttctttctg ttgcctgccc
      841 agcccatgat atcagtaaag tgctctccct tccacctgaa gtcacgctgt gtgctgatgg
      901 gagatgcagc tcatgccatc gtcccatttt ttgggcaagg aatgaatgcg ggctttgaag
      961 actgcttggt atttgatgag ttaatggaca aattcaataa tgatcttagt gtgtgccttc
     1021 ctgaattctc aagatttagg attcctgatg accatgcaat ttcagacctg tctatgtaca
     1081 attacataga gatgcgagcg catgtcaact ctaggtggtt cctgtttcaa aggctcctgg
     1141 ataaatttct tcatgcacta atgccatcca ctttcatccc tctctatacc atggtcgcct
     1201 tcaccagaat aagataccac gaggcagtgc tgcgctggca ttggcaaaaa aagataaaac
     1261 ctgtctcgag tctacagact gtggaacatg cactctacct atgggggtgg ggaagcaaag
     1321 agaacttggt gataaacaga ggactctttg tccttgggtc cctggtagcc attggaagtg
     1381 cctacatact cgtgcaccac ctgtccccga gacctctgga actcctgaga tctgcctgga
     1441 cgggaacctc tggccactgg aataggagtg cagacatttc tccacgagtt ccatggagtc
     1501 actaggacaa atgccccagt tcactatcca tagtgtcaac gttccgggta gcaaatgctt
     1561 gattcctctt caatatcaag ggagaaactc atgttcccat tgccgtcttc agttcactat
     1621 gggaaaatca ttgtcagcat ataattaagt tcggagtgga gggctgtttt tacagtgtct
     1681 cattattttg catgcttgga ctgggttcaa tttttaaatt taaaaacaca ataaccaaag
     1741 tctctttcac ttctcaaaaa aatttttttt cctatagagg acaatacagg atcaaaaaca
     1801 ccaggactga aaaccacagc ttgcctggtg ctaattcctc tttatagcag tggtggggtt
     1861 tgctagttca tagccacttg ctaaaggtag aggtgtgaat gttccaaaca gggtgttcca
     1921 aagagttcca ggataaatct gttaaattat ttcccagtcc ccagacctca gaattattac
     1981 tgttttgaag ataaggaaag ggctattaat ggcatcttaa gtgaaggata agaaagggtt
     2041 gttagtagta atacatttat accagggtgg agaggagatg ggagggtgtt ttctagaagc
     2101 atagagacgc acagttcatt gcatttcaga catgcagaag tgattcgttg actgtcccac
     2161 agacagaatc ggaagttaac ttcatcatca gagactggga cacttagaaa ttcttttcat
     2221 tgtcaatttt gagagctaca ataatagtta tctaggaaat ccaaaactga ggttataaag
     2281 ataaaacaat ttggcatttt ccataatgcc aaaagcatcc tcgagtctta acagtctatg
     2341 tttgaggtgt agggaaagaa aaatcattct tttcctggta agggatgtag ctcagtgggg
     2401 agtgtagcat gggtagagcc cagggttaga ttcaccagca ctgcaaaaat aaacagaaca
     2461 atagtttagg agcatgcatg tatatttcat atggacatgg gaaacgctca gaaatgagct
     2521 gacttagggg ctagggagat ggctcagctg ttaagtatgt gtgccactcc tgaagaggct
     2581 cctagttccg tccccagcac ccatttcagg cagcccagtt ggaactccag ctccaggaga
     2641 tccaacccct ctggcttcct tgggcccctg cacccatgtg catataacca cacatggctc
     2701 cacaagggaa ttaaaagtct ttaacaatca taatttctgg aagaggcaag ggggtgtatg
     2761 ggaggagtta gacggaaaaa aagtaaggga ggaaatgatg caatttaaag ttaaacaaaa
     2821 gaatagt
//
