LOCUS       NM_001012648             837 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus killer cell lectin-like receptor family I member
            2 (Klri2), mRNA.
ACCESSION   NM_001012648
VERSION     NM_001012648.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Saether,P.C., Westgaard,I.H., Hoelsbrekken,S.E., Benjamin,J.,
            Lanier,L.L., Fossum,S. and Dissen,E.
  TITLE     KLRE/I1 and KLRE/I2: a novel pair of heterodimeric receptors that
            inversely regulate NK cell cytotoxicity
  JOURNAL   J Immunol 181 (5), 3177-3182 (2008)
   PUBMED   18713988
  REMARK    GeneRIF: KLRE1-KLRI2 heterodimer is a functional activating
            heterodimer in NK cells
REFERENCE   2  (bases 1 to 837)
  AUTHORS   Saether,P.C., Westgaard,I.H., Flornes,L.M., Hoelsbrekken,S.E.,
            Ryan,J.C., Fossum,S. and Dissen,E.
  TITLE     Molecular cloning of KLRI1 and KLRI2, a novel pair of lectin-like
            natural killer-cell receptors with opposing signalling motifs
  JOURNAL   Immunogenetics 56 (11), 833-839 (2005)
   PUBMED   15650876
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY324871.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY324871.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676788 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="F344"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..837
                     /gene="Klri2"
                     /note="killer cell lectin-like receptor family I member 2"
                     /db_xref="GeneID:503650"
                     /db_xref="RGD:1359205"
     exon            1..246
                     /gene="Klri2"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..776
                     /gene="Klri2"
                     /codon_start=1
                     /product="killer cell lectin-like receptor subfamily I
                     member 2"
                     /protein_id="NP_001012666.1"
                     /db_xref="GeneID:503650"
                     /db_xref="RGD:1359205"
                     /translation="MPRKKQNERGTNKQEIINIETKSSTFQEKQRQSKTDQISTVWRK
                     EQKKQELKVHTELHPQHRTGFNEDKGTDPWLTTWRIITVILGTSCIILVTKVGFLIPN
                     LFSRGEKRSRELSLLDSLCLKNNDSFCDLCSHDWIAFGNNFYLFFRGTKTWAESKSAC
                     EELNSYLLDIDSRAELENLLLFEINGWILFKTDAINRSLRKNYIKIHQTLFNDSEKKN
                     HSCHYLSGNQFSAGDCSSKKAYTCEFNLQ"
     exon            247..339
                     /gene="Klri2"
                     /inference="alignment:Splign:2.1.0"
     exon            340..408
                     /gene="Klri2"
                     /inference="alignment:Splign:2.1.0"
     exon            409..560
                     /gene="Klri2"
                     /inference="alignment:Splign:2.1.0"
     exon            561..661
                     /gene="Klri2"
                     /inference="alignment:Splign:2.1.0"
     exon            662..837
                     /gene="Klri2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctataacag tcttttcaga acaaaaaaga gaatgcccag gaaaaagcaa aatgaacgtg
       61 gaacaaacaa acaagagatt attaacatag aaacaaaatc ttccacattt caagagaagc
      121 agagacaatc caagacagac cagatatcta ctgtgtggag aaaagaacag aaaaaacagg
      181 aactgaaagt tcacacagaa ttacaccccc aacacaggac tgggttcaat gaagacaaag
      241 gaacagatcc ctggttgaca acatggcgaa taataactgt catcctagga acctcatgta
      301 ttattttggt gacaaaagtg ggcttcttga ttccaaactt attttctagg ggagaaaagc
      361 gaagcagaga gctctccctt ctggattctc tgtgtcttaa gaataatgac tccttctgtg
      421 atctttgttc ccatgactgg attgcttttg gaaacaattt ctatctcttt tttcgtggaa
      481 ccaaaacctg ggcagagagt aagtcggcct gtgaggaact gaattcttat cttctggaca
      541 tagactccag agcagagctg gaaaatttgt tactatttga aattaatggg tggattctct
      601 tcaaaacgga tgcaataaac aggtccttgc ggaaaaatta cattaaaata caccaaaccc
      661 tatttaatga ttcagaaaag aagaatcata gctgtcatta tctgagtgga aaccaattca
      721 gtgctggtga ctgttcatct aagaaagcat acacctgtga atttaatcta cagtgacacc
      781 tatatcagta tcataattta tttgattatg aacatcaaaa tttcttttat ttgttga
//
