LOCUS       NM_001012649            1102 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus killer cell lectin-like receptor family I member
            1 (Klri1), mRNA.
ACCESSION   NM_001012649
VERSION     NM_001012649.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1102)
  AUTHORS   Saether,P.C., Westgaard,I.H., Hoelsbrekken,S.E., Benjamin,J.,
            Lanier,L.L., Fossum,S. and Dissen,E.
  TITLE     KLRE/I1 and KLRE/I2: a novel pair of heterodimeric receptors that
            inversely regulate NK cell cytotoxicity
  JOURNAL   J Immunol 181 (5), 3177-3182 (2008)
   PUBMED   18713988
  REMARK    GeneRIF: KLRE1-KLRI1 heterodimer is a functional inhibitory
            heterodimer in NK cells
REFERENCE   2  (bases 1 to 1102)
  AUTHORS   Saether,P.C., Westgaard,I.H., Flornes,L.M., Hoelsbrekken,S.E.,
            Ryan,J.C., Fossum,S. and Dissen,E.
  TITLE     Molecular cloning of KLRI1 and KLRI2, a novel pair of lectin-like
            natural killer-cell receptors with opposing signalling motifs
  JOURNAL   Immunogenetics 56 (11), 833-839 (2005)
   PUBMED   15650876
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001012649.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY286494.1, FQ233804.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               JAXUCZ010000004.1  164904724-164904868 c
            146-417             JAXUCZ010000004.1  164901215-164901486 c
            418-510             JAXUCZ010000004.1  164890357-164890449 c
            511-570             JAXUCZ010000004.1  164890165-164890224 c
            571-722             JAXUCZ010000004.1  164871317-164871468 c
            723-823             JAXUCZ010000004.1  164870715-164870815 c
            824-1102            JAXUCZ010000004.1  164869695-164869973 c
FEATURES             Location/Qualifiers
     source          1..1102
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1102
                     /gene="Klri1"
                     /note="killer cell lectin-like receptor family I member 1"
                     /db_xref="GeneID:503651"
                     /db_xref="RGD:1359344"
     exon            1..145
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
     exon            146..417
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
     CDS             201..932
                     /gene="Klri1"
                     /codon_start=1
                     /product="killer cell lectin-like receptor subfamily I
                     member 1"
                     /protein_id="NP_001012667.1"
                     /db_xref="GeneID:503651"
                     /db_xref="RGD:1359344"
                     /translation="MPHSKHRDYTADKQDIPYTELKACKSPWKHRTPAVKQSPVVLSE
                     EQLKYAELTFHRTPQLQPRKQTVRRKRQGPKSAVWRVVTCVLGVLCVVLMITMGILVP
                     KLFSGQEEQYRETSLHHLLKNDSSCDPCSHDWIAFGNNFYLFFRGTKSWAESKSACEE
                     LNSHLLDIDSKAELENLLLFEINGWILVKKNQTNWSSSENETKLQHTLIDEKKNHSCR
                     YLRGSQFIADDCSSKKPYACEFNKM"
     exon            418..510
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
     exon            511..570
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
     exon            571..722
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
     exon            723..823
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1102
                     /gene="Klri1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgcaactta gaactctccc ggacgattgg aaacatatta tcggttgtcc aattttattc
       61 atctagtgaa acactggggc attgtttaat tcttggattc tttgataaaa ctttcagaca
      121 tactcctcta ggataaatac tttggagata ctccagaaca agagcagcaa gctaccagga
      181 ctgacgggaa gcagaacaaa atgccccaca gtaaacaccg tgattataca gcggacaagc
      241 aggatattcc atacacagag ctaaaggcat gtaagtctcc atggaagcac agaacacctg
      301 cagtcaagca gagccctgta gtgctaagtg aagagcagct aaaatatgca gagttgacat
      361 tccacagaac accccagctc cagcccagaa aacaaactgt cagaaggaaa agacaaggac
      421 ccaaatcagc agtatggaga gtggttactt gcgtgcttgg ggtcttgtgt gtggtgctga
      481 tgataaccat ggggatctta gttccaaaat tattttctgg tcaagaagag caatacagag
      541 aaacctcact tcatcatctt ctgaagaatg actcctcctg tgatccttgt tcccatgact
      601 ggattgcttt tggaaacaat ttctatctct tttttcgtgg gaccaaatcc tgggcagaga
      661 gcaagtctgc ctgtgaggaa ctgaattctc atcttctgga catagactcc aaagcagagc
      721 tggaaaattt gttactgttt gaaattaatg ggtggattct tgtcaaaaag aatcaaacta
      781 actggtcctc gtctgaaaat gaaactaaac tacagcatac cctaattgat gaaaagaaga
      841 atcatagctg tcgttacctg cgtggaagcc aattcattgc tgatgactgc tcatctaaga
      901 aaccatacgc ctgtgaattt aataaaatgt gatgcctatt tcactagcat aattttgttt
      961 aattatgaac atcaagatgt ctgttgtttg ttgaatatat tattttttac acttgatctt
     1021 tgtcaaaatg ccaatgatga taatttttaa attttgaaga tgttttactg aactgagatg
     1081 ctgattaaaa ttttactatc ta
//
