LOCUS       NM_139187                855 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus killer cell lectin-like receptor subfamily H,
            member 1 (Klrh1), mRNA.
ACCESSION   NM_139187
VERSION     NM_139187.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 855)
  AUTHORS   Daws MR, Dai KZ, Zinocker S, Naper C, Kveberg L, Hedrich HJ,
            Rolstad B and Vaage JT.
  TITLE     Identification of an MHC class I ligand for the single member of a
            killer cell lectin-like receptor family, KLRH1
  JOURNAL   J Immunol 189 (11), 5178-5184 (2012)
   PUBMED   23100519
  REMARK    GeneRIF: RT1-A2 MHC class I antigen is a ligand for the single
            member of a killer cell lectin-like receptor family, KLRH1.
REFERENCE   2  (bases 1 to 855)
  AUTHORS   Naper C, Hayashi S, Lovik G, Kveberg L, Niemi EC, Rolstad B, Dissen
            E, Ryan JC and Vaage JT.
  TITLE     Characterization of a novel killer cell lectin-like receptor
            (KLRH1) expressed by alloreactive rat NK cells
  JOURNAL   J Immunol 168 (10), 5147-5154 (2002)
   PUBMED   11994469
  REMARK    GeneRIF: The MHC haplotype of the host appears to influence Klrh1
            expression, suggesting that it may function as an MHC-binding
            receptor on subsets of NK cells and T lymphocytes.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF416564.2.
            
            On Jul 3, 2002 this sequence version replaced NM_139187.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF416564.2 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN06680417,
                                           SAMN06680419 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..855
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="PVG"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..855
                     /gene="Klrh1"
                     /note="killer cell lectin-like receptor subfamily H,
                     member 1"
                     /db_xref="GeneID:246043"
                     /db_xref="RGD:621452"
     exon            1..61
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..754
                     /gene="Klrh1"
                     /note="killer cell lectin-like receptor 1"
                     /codon_start=1
                     /product="killer cell lectin-like receptor subfamily H,
                     member 1"
                     /protein_id="NP_631926.1"
                     /db_xref="GeneID:246043"
                     /db_xref="RGD:621452"
                     /translation="MQLSEMNEGRLTYAELKLSLKSKDKPQPTQKKREYPWRISVVIL
                     GTVCLCLLISSIVFGYLFFQGTSKFKIQCEKDANKNAVSSMEVVDPSALPPTTGKGCY
                     KCQGRWFCCGEKCYYFSEEEKTWDESEASCRLLGSHLAKIDNREEQNFIQSRLNYSYW
                     VGLRKKGGQFLWVHQEDEKISSDLDFHMTTHLADAACGYIKPKLLNNAQCSRLFPYIC
                     KKNFTCLLTSENW"
     exon            62..158
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
     exon            159..242
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
     exon            243..350
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
     exon            351..502
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
     exon            503..609
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
     exon            610..817
                     /gene="Klrh1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaccacccc tgcgctccag ctgatgaaaa gcaaaaatag agccaggaaa catcagagat
       61 gcagctatca gaaatgaatg agggaagact gacatatgca gagctgaaat tatccctgaa
      121 gagtaaggac aaaccccagc caactcagaa aaagagagaa tatccatggc gcataagtgt
      181 tgtgatcctg ggaacagtat gtctttgtct tctgatatca agcatagtct ttggatatct
      241 gttttttcag ggcacatcaa agttcaaaat tcaatgtgag aaagatgcaa ataaaaatgc
      301 tgtctcctca atggaagtag tagatccttc agctttacca cctacaacag gaaaaggctg
      361 ctacaaatgt caaggaagat ggttttgctg tggagaaaag tgttactact tttcagaaga
      421 ggaaaagaca tgggatgaaa gtgaggcatc ctgcaggctc ctgggttctc atcttgctaa
      481 gattgacaat agagaggagc agaactttat tcagtcacga ttgaactata gctattgggt
      541 tggattacgt aaaaaaggag gtcaattcct gtgggtacat caggaggatg aaaaaatttc
      601 ttcggatttg gattttcaca tgacaaccca tttagcagat gcagcatgtg gatatatcaa
      661 gccaaagctt ctcaacaatg ctcaatgtag tagacttttc ccctatattt gtaaaaagaa
      721 ttttacctgc ctgttgacat cagagaattg gtaaaatcac acttttacta tttttattcc
      781 ttagtggcta ttagcaaaat aaaattcatc caagtcaaaa aaaaaaaaaa aaaaaaaaaa
      841 aaaaaaaaaa aaaaa
//
