LOCUS       NM_001105995            3149 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus kelch-like family member 8 (Klhl8), mRNA.
ACCESSION   NM_001105995 XM_001065538 XM_213995
VERSION     NM_001105995.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3149)
  AUTHORS   Nam,S., Min,K., Hwang,H., Lee,H.O., Lee,J.H., Yoon,J., Lee,H.,
            Park,S. and Lee,J.
  TITLE     Control of rapsyn stability by the CUL-3-containing E3 ligase
            complex
  JOURNAL   J Biol Chem 284 (12), 8195-8206 (2009)
   PUBMED   19158078
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474022.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_213995.4, XM_001065538.1.
FEATURES             Location/Qualifiers
     source          1..3149
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..3149
                     /gene="Klhl8"
                     /note="kelch-like family member 8"
                     /db_xref="GeneID:289457"
                     /db_xref="RGD:1304685"
     exon            1..133
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            134..501
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     CDS             283..2148
                     /gene="Klhl8"
                     /note="kelch-like 8"
                     /codon_start=1
                     /product="kelch-like protein 8"
                     /protein_id="NP_001099465.1"
                     /db_xref="GeneID:289457"
                     /db_xref="RGD:1304685"
                     /translation="MASESTNGKLARSHVTKGRRQQQQQQQVRSRSSVSECDGDDSFI
                     FEANEAWKDFHGSLLGFYENGELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMS
                     EAKQALIEIRDFDGDAVEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEY
                     MKLHFHPSNCLAVRAFAESHNRTDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLL
                     SSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQVRLPLLPVDFLMGVVAKEQI
                     VKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGVLFCVGGRGGSGDPF
                     RSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTN
                     KWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMNTP
                     RGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHG
                     CLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGN
                     AYLNTVEAFDPVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM"
     exon            502..1050
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1237
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1381
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..1493
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1662
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1822
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..2024
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
     exon            2025..3149
                     /gene="Klhl8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgctccgcg gagccgggca cgagcaagcg ggcgggcaag tgagcgcgtc cgccgagtgt
       61 cggagctggg ctggcgcggc gccggcacgg agcgggtgtg gcggctcggc ctgcgcggcg
      121 gccgcggaca gagcaaactg tctaatgaaa ttgaaggttt cgaaagatgt ctaaagctta
      181 gtggccacat ctatcgtctg tcttctgacc cttaaaaaaa aaaaaacaaa gaataaatgg
      241 gatgtttcag aagagagcta tttaaaagga agagtgttgc aaatggcttc agaatctacc
      301 aatgggaagc tagctaggag tcacgtgaca aaggggcggc gtcagcagca gcagcagcag
      361 caggtgagga gccggtcctc tgtcagcgag tgcgatggcg acgactcctt catcttcgaa
      421 gccaacgagg cctggaagga ctttcacggc tctctcctgg gcttctatga gaacggggag
      481 ctctgtgacg tcactctaaa ggtcggctcg aagctcatct cctgccacaa gctggcgctg
      541 gcttgtgtca tcccctactt cagagccatg tttctttctg aaatgtctga ggctaagcag
      601 gcgctgatcg agattcggga ctttgacggc gatgccgtgg aggacttggt gaagttcgtc
      661 tactcttcgc ggctcactct gacagtggac aacgtccagc ctctgctgta tgcagcgtgc
      721 atcctgcagg ttgaactggt ggccagagct tgctgcgaat acatgaagct acactttcat
      781 ccctccaact gcctggctgt gcgagccttt gcggagagtc acaaccgaac agacctaatg
      841 gacatggcgg accagtatgc gtgcgagcac tttactgaag tggtagagtg tgaggacttc
      901 gtgagcgtgt ccccacagca cctgcacaag ctcctctcct ccagcgacct caacatcgac
      961 agcgagaagc aggtctacag tgccgccatc aagtggcttc ttgccaaccc acagcatcac
     1021 cctaaatggc tggacgagac ccttgcccag gtccgtctgc cactcttgcc agtggatttc
     1081 ctcatgggcg ttgtggcaaa agagcagatt gtcaagcaaa atctgaaatg tagagaccta
     1141 ctggatgaag ccagaaatta ccaccttcat ttgagcagta aaccagttcc tgactttgag
     1201 tattcagtcc gaactacccc gaggaagcat actgctggtg tgctgttctg tgtgggtggt
     1261 cgaggtggat ctggtgaccc ctttcgtagt atcgaatgct attctatcaa cacaaacagc
     1321 tggttctttg gaccagaaat gaacagccgc aggaggcatg tgggcgtgat ctctgtggaa
     1381 gggaaagtgt atgccgtggg cggccatgat gggaacgagc acctaggcag catggagatg
     1441 tttgaccctc tcactaacaa atggatggtg aaggcatcga tgaacaccaa gaggcgagga
     1501 attgccttgg cctccttagg gggcccaata tatgcgattg gaggattaga tgacaacact
     1561 tgcttcagtg acgtggagag atacgacatt gaatctgacc agtggagtac ggtggcgcca
     1621 atgaacactc cccgtggagg tgtcggctct gtggctttaa tcaaccatgt ttacgcagtg
     1681 ggtggcaacg atggcgtagc ctccttgtcc agtgtggaaa ggtatcaccc gcatctggat
     1741 aagtgggtgg aggtgaagga gatgggccag cggagagccg gcaatggtgt tagtgagctt
     1801 cacggctgct tatacgttgt tggtggtttt gatgataatt cccctctgag ttcggttgag
     1861 cggtacgatc ctcggagcaa caagtgggac tatgtggcag cgctcaccac tcccaggggt
     1921 ggcgtaggga ttgcgacggt gatgggcaag atctttgcag tcggaggcca caacggcaat
     1981 gcctacctca acacagtgga ggcgttcgac cctgtgctga ataaatggga actggtcgga
     2041 cctgtgtctc actgccgagc tggtgccggt gtggccgtgt gtgactgctt aactagccag
     2101 atccgagacg taggtcatgg gtccactaac gtggttgact gtatgtgatt aagtcccagc
     2161 aacaaggata cagtgccatc tgatggacgg gaagacgagc ctttcaacat ggcgcatttg
     2221 attgtgacca cagctactgt ctttgagtgt cagctgttgt aagtaggtct gtgggctgac
     2281 ggtgagagct gctagtcaca gagtgaagtg agctgtttcc tgcctcagca gacagtgagt
     2341 aggctggaag cagcctgtca gcccattctt gcgctgagag acgtttcatg tagtgccaaa
     2401 ccttaaaata gctgtttatt ttgatgaata aaatgtaatt tattgagttt tatctgttct
     2461 ttttcctgaa gaaactaact tcaggcagta gatttttttc ccagaggaga gagaagtcca
     2521 ctcatcaaca tgagaacttg aggcctgctc ccttgaggat cactctacat ggtgctggtg
     2581 aatgtatgtc ttgctttttg tctccagatg gtgactttca gttcttgggt gtttatgaag
     2641 tagggaaaat gtttgtgtgt ttctgagaca ttcttgaaac cacattagtg tctgtaagaa
     2701 ggccttggcc tccatgtgga gttttagaac cacaggacat agctgtgcct gcttcctcac
     2761 caagtgtact ggccgccatt cttttcccat tcgtgagagt ttcttggtga tgaccgtggc
     2821 ttggcatgag tgcagcgtcc agtgaaaaga ctgagaagga tgtatgaagc ccatgcccac
     2881 ctagggaggt tgtggaggct cctttaacct tgttcttctg cttagtcgtt gaatttggaa
     2941 ccaggaccca ttttctctta ctctgtcatt tgtcgccgtc ttgggtttcc taattgtaca
     3001 aagctgaatt tatttattat caggacatga atgcgttttt acaacattcc tttctgcagt
     3061 atagtctgat gattagttcc agtttgtcat taatcaataa aatatgttgc tggtaaaaac
     3121 agaaaaaaaa tgtaaactgc tagtttttt
//
