LOCUS       NM_001047093            3421 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus kelch-like family member 5 (Klhl5), mRNA.
ACCESSION   NM_001047093 XM_001071628 XM_223418
VERSION     NM_001047093.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3421)
  AUTHORS   Yu Y, Kranzler HR, Panhuysen C, Weiss RD, Poling J, Farrer LA and
            Gelernter J.
  TITLE     Substance dependence low-density whole genome association study in
            two distinct American populations
  JOURNAL   Hum Genet 123 (5), 495-506 (2008)
   PUBMED   18438686
REFERENCE   2  (bases 1 to 3421)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY641809.1.
            
            On or before Sep 15, 2006 this sequence version replaced
            XM_223418.4, XM_001071628.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY641809.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3421
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..3421
                     /gene="Klhl5"
                     /note="kelch-like family member 5"
                     /db_xref="GeneID:305351"
                     /db_xref="RGD:1309661"
     exon            1..546
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     CDS             167..2293
                     /gene="Klhl5"
                     /note="myocardial ischemic preconditioning associated
                     protein 6; kelch-like 5"
                     /codon_start=1
                     /product="kelch-like protein 5"
                     /protein_id="NP_001040558.1"
                     /db_xref="GeneID:305351"
                     /db_xref="RGD:1309661"
                     /translation="MSGSRKEFDVKQILKIRWRWFGHQASSNSSVDSQQGEFWSRGQT
                     GANGGRKFLDPCNLQLPLASIGYRRSSQLDFQNSPSWPMASTSDVPAFEFTAEGCGGA
                     HWLDRPEVDDGTSEEENESDSSSSRTSNSSQTLSSCQTMEPCSSDEFFQALNHAEQTF
                     KKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEIKMEG
                     VEPNSLWSLIQYAYTGRLELKEENIECLLSTACLLQLSQVVEACCKFLMKQLHPSNCL
                     GIRSFADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPANEIAKLLASDDMNIPNEE
                     TILNALLTWVRHDLEQRQKDLSKLLAYIRLPLLAPQFLADMENNALFRDDIECQKLIM
                     EAMKYHLLPERRPMLQSPRTKPRKSTVGTLFAVGGMDSTKGATSIEKYDLRTNMWTPV
                     ANMNGRRLQFGVAVLDDKLYVVGGRDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLG
                     VAVLEGPMYAVGGHDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAV
                     GGRDGSSCLKSVECFDPHTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPTSNLT
                     SRLSDCVERYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDGQTYLNIVEAYD
                     PQTNEWTQVAPLCLGRAGACVVTVKI"
     exon            547..729
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            730..866
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1063
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1276
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1463
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1464..1688
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1851
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            1852..2064
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..2236
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
     exon            2237..3404
                     /gene="Klhl5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgggatga aagtaaatgt ggatatatat cccaacgatt tatttccctt taaagctgtt
       61 tgttggctac agcggggaat agactcctct tgtcttggtt ggatgcacag atctgtgcgc
      121 cttgcttttt gcccgttgcc tagacgatca ctcggtttct ctgaggatgt ctggttctcg
      181 caaagagttt gatgtgaagc agattttgaa aatcaggtgg aggtggtttg gccatcaggc
      241 atcatctaat tcttcagttg acagccagca gggagaattt tggagccgag gacagactgg
      301 agcaaacggt gggagaaagt ttttagatcc gtgtaaccta caactgcctt tggcttcaat
      361 tggttaccgg aggtccagcc aactggattt tcagaattca ccttcttggc caatggcatc
      421 cacctccgat gtccctgcat ttgagtttac agcagaaggc tgtggcggtg cacactggct
      481 ggatagacca gaagtggacg atggcactag tgaagaggaa aatgaatctg attccagctc
      541 gagcaggact tccaatagta gtcagacatt gtcatcctgc cagactatgg agccatgttc
      601 atcggatgaa ttctttcaag cccttaacca tgcggagcaa acatttaaaa aaatggaaaa
      661 ctacttgagg cacaagcaac tgtgcgatgt cattttagtc gctggcgatc gcaggattcc
      721 agctcacaga ctggtgctgt cttccgtctc agattatttc gctgctatgt ttactaacga
      781 tgtcagggag gcgaggcaag aagaaataaa aatggaaggc gtagaaccga actccttgtg
      841 gtccttaatt cagtacgcat acacaggccg acttgagctg aaggaagaga acatcgagtg
      901 tctgctgtcc acggcatgcc ttctccagct ctcccaggtg gtggaagcct gctgcaagtt
      961 tctgatgaaa cagctccacc cgtccaattg ccttgggatt cggtcttttg ccgatgccca
     1021 aggctgcaca gatttgcata aagtggctca caattacact atggaacatt tcatggaagt
     1081 gatcagaaac caggaatttg tattactccc agccaatgaa attgccaagc tcttggccag
     1141 tgacgacatg aacattccca atgaggagac catactgaat gcacttctca cctgggtccg
     1201 gcacgatttg gagcagagac agaaagatct cagcaagctt ttggcttaca ttaggctacc
     1261 tctccttgca ccacagttcc tggcagacat ggaaaacaat gcacttttcc gggatgacat
     1321 agaatgtcag aaacttatca tggaagcgat gaagtatcat ttattacctg agaggcggcc
     1381 catgttgcag agtcctcgga caaagcctcg gaagtcaact gtcggaacat tatttgcagt
     1441 cggaggaatg gattcaacaa agggagcaac aagcattgag aaatatgacc tccgtaccaa
     1501 tatgtggact cctgtggcaa acatgaacgg gaggcggcta cagttcggtg tcgcagtatt
     1561 agatgacaag ctgtacgtgg tcggagggcg agatgggctg aagactttga acaccgtaga
     1621 gtgctacaac cccaaaacaa aaacctggag tgtgatgccg cctatgtcca cacacaggca
     1681 cgggctgggt gtggcggtac tggaaggccc catgtacgca gtcggagggc acgacggctg
     1741 gagctatctg aatactgtgg agcgatggga ccctcaggcc cgccagtgga attttgttgc
     1801 cactatgtcc actcccagga gcacagtagg tgtggcagta ctgagtggaa aactttatgc
     1861 agttggtggc cgcgatggga gttcctgcct caagtcagta gaatgctttg accctcatac
     1921 caataaatgg acactgtgtg cccagatgtc aaaaaggaga ggcggtgtag gagtcacgac
     1981 ctggaatgga ctgctgtatg ccatcggtgg gcacgatgct cccacatcca acttgacttc
     2041 caggctctcg gactgtgtgg agagatatga tcccaaaaca gacatgtgga ctgcagtggc
     2101 atccatgagc attagccgag atgcggtggg cgtgtgttta cttggtgaca agctgtatgc
     2161 tgttgggggt tatgacggac agacctacct gaacatagtg gaggcttatg acccccagac
     2221 caatgaatgg acccaggttg caccgctgtg cctaggaaga gctggagcgt gtgttgtgac
     2281 tgtgaagata tgacgtccta cttcatcctc tgcagagaga tgctctctct ctctctctct
     2341 aatagacagt cctcccatgg gtttgttttt tagtgaacgt gcagtgccac atcactaggc
     2401 acaaagtgcc tcatttcaga atgaagatgt tgaaacgatg gggatacacc aggacgggat
     2461 acttcatttc tccatacatt agagccacag ctggaggact gggaacatat cttcttggta
     2521 tacaatatga acacaagtgc actgccccca gaaccaccca gcaccaactg gagtcacatt
     2581 gtccagagtt atcacagtac aagcatacaa taatatttta ttgtacatct aaaacatttt
     2641 ataagtttgt catacatgag cttccatagt ttttatcgtt taatcaaact actattttaa
     2701 tgacatacta aagactatgc tagctagctt tttcaggtac aatgattatg tatgatagtt
     2761 gggaatttta ttactaaaat tggtataacc caagaataaa gaaaaacaca taaggcatta
     2821 aaaataagac tgaccaaata aagacttgac tggatctctg ggtcctactt aaatagccat
     2881 tcctttccat ctagatccat caagacctgc gataggatag cactgagatt aaagcagggt
     2941 gcttacgata agatatgcaa gtttgtgtag agaaagtaaa tgctatatgc tgtctgatgt
     3001 tctcccacct aactagtatt taattatggg ggtttatctt cttttatatt gcaaactttt
     3061 atttgatttt gtccttttga tactgacaca atcgttaggc tgttcctgtg ttctgtctgc
     3121 tgccttgttc caaacatgcg gacacagtta ggaacccatt gtgcttcttt gtaataaaaa
     3181 aactgggggg tagcagggga catgttaact gaatatttga aaaataagtt taaagcattt
     3241 gttactccaa attttgtaca tttgtaaact ctaattacac atgtgaatgt taatagtgtc
     3301 tggattgttt attgtttgta aaatgcccag ggcagcaata ttgtatgaaa ttccccttta
     3361 agagaaaagt cattacctta atataaaaat tgatataaac taaaaaaaaa aaaaaaaaaa
     3421 a
//
