LOCUS       NM_001109257            3228 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus kelch-like family, member 42 (Klhl42), mRNA.
ACCESSION   NM_001109257 XM_001074361 XM_575725
VERSION     NM_001109257.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3228)
  AUTHORS   Cummings CM, Bentley CA, Perdue SA, Baas PW and Singer JD.
  TITLE     The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for
            normal mitosis in mammalian cells
  JOURNAL   J Biol Chem 284 (17), 11663-11675 (2009)
   PUBMED   19261606
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473964.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_575725.2, XM_001074361.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3228
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..3228
                     /gene="Klhl42"
                     /gene_synonym="Klhdc5; RGD1560924"
                     /note="kelch-like family, member 42"
                     /db_xref="GeneID:500367"
                     /db_xref="RGD:1560924"
     exon            1..881
                     /gene="Klhl42"
                     /gene_synonym="Klhdc5; RGD1560924"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..1527
                     /gene="Klhl42"
                     /gene_synonym="Klhdc5; RGD1560924"
                     /note="kelch domain-containing protein 5; kelch domain
                     containing 5"
                     /codon_start=1
                     /product="kelch-like protein 42"
                     /protein_id="NP_001102727.1"
                     /db_xref="GeneID:500367"
                     /db_xref="RGD:1560924"
                     /translation="MSAEEMVQIRLEDRCYPVSKSKLIEQSDYFRALYRSGMREAVRP
                     EVGPEVQQLRGLSAPGLRLVLDFINAGGAREGWGLSEDELAEASVLAEMVEAASFLQV
                     TALLRLLLSHVRLGNCLELYRLAQVYGLPDLQDACLRFMVLRFHQVLCQPQFPLLLSP
                     PQAPGDCSLKQRLREARMRGTPVLVALGDFLGGPLAPHPYQGEPPSMLRYEETTERWF
                     PLANNLPPDLVNVRGYGSAILDNYLFIVGGYRITSQEISAAHSYNPTTNEWLQVASMN
                     QKRSNFKLVAVNSKLYAIGGQAVSNVECYNPEQDAWNFVAPLPNPLAEFSACECKGKI
                     YVIGGYTTRDRNMNILQYCPSADLWTLFETCDVHIRKQQMVSVEETIYIVGGCLHELG
                     SNRRSSQSEDMLTVQSYNTETRQWLYLKENTSKSGLNLTCALHNDGIYIMSRDVTLST
                     SLEHRVFLKYNIFADSWEAFRRFPAFGHNLLISSLYLPNKAET"
     exon            882..1075
                     /gene="Klhl42"
                     /gene_synonym="Klhdc5; RGD1560924"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..3228
                     /gene="Klhl42"
                     /gene_synonym="Klhdc5; RGD1560924"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggaggagc ctgagcagcc gggcggcggg cgcagcggcc cagccatgtc ggccgaggag
       61 atggtgcaga tccgcctgga agaccgctgc tacccggtga gcaagagcaa attgatcgaa
      121 cagagcgact acttccgcgc tctctaccgc tccggcatgc gcgaggccgt gcggcccgag
      181 gtgggtccgg aggtgcagca gctgcgcggc ctgagcgctc cgggcctgcg gctggtgctg
      241 gacttcatca acgcgggcgg cgcgcgcgag ggctggggcc tgagcgagga cgagttggcc
      301 gaggccagcg tgctggccga gatggtggag gccgcgtcct ttctgcaggt cacggcgctg
      361 ctgcgcttgc tgctgtcgca tgtgcgtctg ggcaactgcc tggagctgta ccgcctggcg
      421 caggtgtacg ggctgcccga cctgcaggac gcctgcctgc gcttcatggt gctgcgcttc
      481 caccaggtgc tgtgccagcc gcaattcccg ctactgctgt cgccgcctca ggcccccggg
      541 gactgcagcc tgaagcagag gttgcgggag gcccgcatgc gcgggacccc ggtcctggtg
      601 gccctggggg acttcctcgg gggacccctg gctccgcacc cgtatcaggg ggaacccccg
      661 tccatgctta ggtatgagga gaccacagag cgctggttcc ccctggccaa caacctgccc
      721 cccgacctgg tgaacgtcag gggctacggc tcagccatct tggacaacta cctcttcatc
      781 gtgggtggtt acaggatcac cagccaggag atctcggccg cacactccta caatcccacc
      841 accaacgagt ggctgcaggt ggcttccatg aaccagaagc gatctaactt caaacttgtg
      901 gctgtcaatt cgaagcttta cgccatcggc gggcaggccg tttctaacgt ggagtgctat
      961 aaccccgaac aagatgcgtg gaattttgtg gctcccctgc cgaaccctct ggctgagttc
     1021 tctgcgtgcg agtgcaaggg gaagatttat gtcatcggtg gatatactac ccgagatcgc
     1081 aacatgaaca tcctgcagta ctgcccctcc gctgacctct ggacgctgtt tgagacctgc
     1141 gacgtccata tccgcaagca gcagatggtg tccgtggagg agaccatcta catcgtgggc
     1201 gggtgtctcc acgaactggg gtccaaccgc aggagcagtc agagcgagga catgctcacc
     1261 gtgcagtcct acaacacgga aactcggcag tggctctacc tgaaggagaa cacgtccaaa
     1321 tcaggcctga acttgacgtg cgcactacac aatgacggca tctacattat gagcagggac
     1381 gtcaccctgt ccaccagctt ggagcaccga gtgtttctca agtacaacat ctttgcggac
     1441 agctgggaag ccttcaggcg gttcccagcc ttcggacaca acttgttgat ttcctctctc
     1501 tatctgccca ataaagcaga gacctgactg attcaacagt acttaaaaga aaaatctggt
     1561 tcaagggggg aaaaaaacga aaggcaagcc tttgaaatat ggactcctga agagacaaag
     1621 tgggctaacg taggtcaagt ggggaggacg gctctgctgt aaataagctt ccttgagcta
     1681 gttacttgaa aacgtggggt aaagagacca accgtattct ttccagattg tttttttgta
     1741 ccatgggaac aaatgtcacg aaaagtattc aaccaaaccg aagcagtctt gggccaacaa
     1801 ctaaaaccca cccttaaaag tagactgccg gggtctgctt tgaacgggtc gaggtcagta
     1861 gctaagatca cagtagcaat ggctttcttc tgtgtttttc ccgttgggaa tggaacccag
     1921 ggcctcacgc gagtcccgaa aggatgactt taaagacact tgcttcaggt cacctgcgat
     1981 ctcgtcagta tggacttttc cttttggtga tcagcgtttg acaagcttta ggatccgccc
     2041 acctctagtc tcctgttccc tgtcacccag gctctctggg cagacatttt atcctatatt
     2101 tgctttcaga aaccccgacg ggcgtgtcca accttttgac atttagaaat tatcattctt
     2161 taactttgtg cacacttgag ttaccttaaa aaaaaacaag cctcttaatg ctctaagtaa
     2221 gttcctgacg ctgtgttggc tgctacatag ctttccttgg ggcccacaag ctgcagttgc
     2281 cttgcctgct acagagatag agccagacag aatccacaca ggcagcccgt ccatccaaaa
     2341 acatggagag acacctcctc agcctttcca gtctttgtgc aattgagaat gctgtgtaag
     2401 gcagacttac ctcttatctc gtgtgtggca gatgagggct ctgttcttag gagagtgcta
     2461 taaacatttt ataagctgag tcttaaggga gagggagtac tgcgtaagga aagatgcctt
     2521 tgtgagttac ttttattgaa tatatgtgac ttagttcttg tttcaagaca aaaaaaaaaa
     2581 aaacccaccc caacttttgc acatttccac caagtttcct cctagcttgg tcttagcctt
     2641 agatacatag ctgtgttttg cctttttaag ggaatggtga ctttagctga tgtggtgcta
     2701 gaaagcaggg gagatgttct ttacagacgt gggatggcct ctgctggcat ttctgaattg
     2761 aagtgaggtg ctggcctcac agctctcctg ccaactgcgg tgagtagcct aaggacctgt
     2821 caatcatggg cctgtgtttc ttaaaagact caagggccca cttagcgtgc acaagaggcc
     2881 cctgggttta atctccagca cttacagcaa cagcaacaag gtcctcacct acagggattt
     2941 tgattgaaga gctgctatct tgtagtggag tcagctaaag gaaccacacc agctgcaggc
     3001 agccgccttg catatttaag tatgctccat agaaaaataa ttagaattac aggcagattt
     3061 tctcccagtt ccttgcacag ctgctcacct ggtggctggg tgtgggggag ggaagctgac
     3121 cccgagtagg tcttcagtgt cgatgaggga gtcacttcag ggtttcttta tagccatgcc
     3181 tctaatacag ccttagagcc tagttataaa actcttactt gcacaact
//
