LOCUS       NM_001107996            3830 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus kelch-like family member 21 (Klhl21), mRNA.
ACCESSION   NM_001107996 XM_001076289 XM_233701
VERSION     NM_001107996.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3830)
  AUTHORS   Maerki,S., Olma,M.H., Staubli,T., Steigemann,P., Gerlich,D.W.,
            Quadroni,M., Sumara,I. and Peter,M.
  TITLE     The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone
            microtubules in anaphase and is required for cytokinesis
  JOURNAL   J Cell Biol 187 (6), 791-800 (2009)
   PUBMED   19995937
REFERENCE   2  (bases 1 to 3830)
  AUTHORS   Furukawa,M., He,Y.J., Borchers,C. and Xiong,Y.
  TITLE     Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin
            ligases
  JOURNAL   Nat Cell Biol 5 (11), 1001-1007 (2003)
   PUBMED   14528312
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_233701.4, XM_001076289.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3830
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3830
                     /gene="Klhl21"
                     /gene_synonym="RGD1305863"
                     /note="kelch-like family member 21"
                     /db_xref="GeneID:313743"
                     /db_xref="RGD:1305863"
     CDS             1..1794
                     /gene="Klhl21"
                     /gene_synonym="RGD1305863"
                     /note="kelch-like 21"
                     /codon_start=1
                     /product="kelch-like protein 21"
                     /protein_id="NP_001101466.1"
                     /db_xref="GeneID:313743"
                     /db_xref="RGD:1305863"
                     /translation="MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGG
                     RDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVS
                     GDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRF
                     ILRHVGELGAEQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWP
                     QLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRM
                     RPRPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLAEFPDHLGGGYSIVALG
                     NDIYVTGGSDGSRLYDCVWRYNSSVNEWTEVAPMLKAREYHSSSVLNGLLYVVAADST
                     ERYDHATDSWEALQPMTYPMDNCSTTACRGRLYAIGSLAGKETMVIQCYDPDTDLWSM
                     VNCGQLPPWSFAPKTVTLNGLMYFVRDDSAEVDVYNPTKDEWDKIPSMNQVHVGGSLA
                     ALGGKLYVSGGYDNTFELSDVVEAYDPETRAWSVVGRLPEPTFWHGSVSIFRQFMPQT
                     PAGGRGFELNSGSSDVDAGHHRLPQNPEELQ"
     exon            1..1021
                     /gene="Klhl21"
                     /gene_synonym="RGD1305863"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1427
                     /gene="Klhl21"
                     /gene_synonym="RGD1305863"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1500
                     /gene="Klhl21"
                     /gene_synonym="RGD1305863"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..3830
                     /gene="Klhl21"
                     /gene_synonym="RGD1305863"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagcggc cggcgccttt ggccgtgctg cccttctccg atcccgcgca cgccctgagc
       61 ctgctgcgcg gcctgagcca gctgcgcgcc gagcgcaagt tcctggacgt gaccctggag
      121 gcggcgggcg gccgcgactt ccccgcgcac cgcgccgtgt tggcggccgc cagtccctac
      181 ttccgcgcca tgttcgcggg ccagctgcgc gagagccgcg ccgagcgcgt gcgcctgcac
      241 ggggtgccgc ccgacatgct gcagctgctc ctggacttca gctacaccgg cagagtggcg
      301 gtgagcggtg acaacgccga gccgctgctg cgcgccgccg acctgctgca gttccccgcc
      361 gtgaaggagg cgtgcggcgc cttcctgcag cagcagctcg acctggccaa ctgcctggac
      421 atgcaggact tcgccgaggc cttcagctgc tccgggctgg cgagcgctgc gcagcgcttc
      481 attctgcgcc acgtgggcga actgggcgcc gagcagctgg agaggctgcc gctggcgcgc
      541 ctgctgcgct acctgcgcga cgacgggctg tgcgtgccca aggaggaggc ggcctaccag
      601 ctggcgctgc gctgggtccg cgcggacccg ccgcgccgcg cggcgcactg gccgcagttg
      661 ctggaagctg tgcgcctgcc cttcgtgcgc cgcttctacc tgctggcaca cgtggaggca
      721 gagcccctgg tggcgcgctg cccgccttgc ctgcgcctgc tgcgcgaggc ccgcgatttc
      781 caggcggctc gctacgaccg gcatgaccgc gggccctgcc cccgcatgcg tccgcgtccc
      841 tccaccggct tggccgagat cctggtactg gtgggaggtt gcgaccagga ctgcgacgag
      901 ctagtcacgg ttgactgcta caatccgcag accgggcagt ggcgctacct ggccgagttc
      961 cccgatcact taggcggggg ctatagtatc gtggcactgg gcaacgacat ctacgtgacg
     1021 ggtgggtccg acggctcccg gctctatgac tgcgtgtgga gatacaactc gagtgtgaac
     1081 gagtggacgg aggtggctcc catgctcaaa gcccgggagt accatagctc ctctgtgcta
     1141 aatgggcttc tgtacgtggt ggcagctgac agcaccgaac gctatgacca cgccactgac
     1201 tcctgggagg ccctgcagcc catgacctac cccatggaca actgctctac cactgcctgc
     1261 cggggccgac tctatgccat cggctccctg gcgggcaagg agaccatggt gatacagtgc
     1321 tatgacccag acaccgatct gtggtcgatg gtgaactgtg gccagctccc accctggtcc
     1381 tttgcaccca agactgtgac tttgaatgga ctcatgtact tcgtcaggga tgactctgct
     1441 gaggtggatg tctataaccc caccaaggac gagtgggaca agatcccatc tatgaaccag
     1501 gtacacgttg ggggcagctt ggccgccctg ggaggcaagc tctatgtctc tggggggtat
     1561 gacaacacct ttgaactctc ggatgtggtg gaggcatatg acccagagac ccgggcgtgg
     1621 agtgtggtgg ggcggcttcc agagcccacc ttctggcatg gcagtgtgag tatcttccgt
     1681 cagttcatgc cgcagacacc ggcagggggc cgtggcttcg agctgaacag tggcagcagt
     1741 gacgtggatg caggccacca caggctgcca cagaaccccg aagagctaca atagcccagg
     1801 cctggcccag aggagggcct tggtgcaagg ggcctggcac ctgtggggga gtggctcagg
     1861 aatgctcagt gagcccctcg aggcaccatg tgaaggtctc tgcattcgga gcctatgtca
     1921 cagcttctgg ggacaaaggc ggtggtgacc accagcatgt atcagccttc agaagtcacc
     1981 tccggtttgt aggatccagc tcaccgctca gggtgcctct ccttgctgcc cgcccttggg
     2041 cctgtgtgct tgccagagca gaaagtcctg tcatggtctg aaagggacct ggcctggagc
     2101 gtttgggaat tcaggaagac aaaggctaaa cgccccatcc ggtaccaagg atccttgtag
     2161 ccagtgctgc aggtagaggg ggtgtgttca caccatcttt ggggtctcgc catacagggg
     2221 ttaagtactg agactaaccc ggagggctgt cacagtgtga gcccaaggtc tgttcctata
     2281 gcacatggtc tcacctggcg aggtgtccct cccgggatcc tgccctggag gacatgagca
     2341 aagctcatga agctggcttg ctgcagctcc tccttgggag cctcaccgac acttggctaa
     2401 gcgcgcagct accaggcctg ggagcggaga ctcctgcttc taaagaggct gcgtggggcg
     2461 tcccagcact tggctgtggg ttcaaaatgc ttgtggtttg acctcgaaaa gaagcaagag
     2521 agttgggagc agtaagagac aagttggctt tgtctggctt gaaggtgtac aacccatcat
     2581 cgggagaatt tttctgcctc gtgtggaaaa cctaggattt ctagggtcgt taggcccagg
     2641 gacacaagta ctaccacggc tttaggggat ccctgggttt ctctgtgact ttgagtggtt
     2701 tcgtgggttt gggagccgag acccctttgt acacagtagg gtttgttatc tttctgggga
     2761 agaggccatt agggctttct gttatggaca aaggcaaagt tgagagttag cttttcctag
     2821 tgatctcaag ggccggtaag gctcttggaa cagaagcctc taccccacca catgcctact
     2881 gctccctcct tggccgggtg gcacctacct gcttcctgtt tgatgctgtg cactgcagat
     2941 gtcaactctt gttgagtttg aaagccgtgt cctagaacgc tctgctgggc acctgaccct
     3001 gggagagaca gtaggcatgg ggcagtgctg tcccgaccca ggcccactgg tgagccaggg
     3061 ttcctttggg gatgtgcagc ggtgccttgt ttctttctct ggggctgccg gcccatcctt
     3121 ccagtgcctc ttctctgaac cttaaagagc tgcctcccag ggccacctgg aggggttgac
     3181 gctctgccac ggagtgcctt tgctcagcag ggcgggggcc tgtgtctgtg tgtgtggtac
     3241 tagtctcact gccggggaca ggctaggagg ctttgcagag gagctgcact gctgcagtcc
     3301 cgcaacctgc agatgttcct gcattacggt gcacacttgc actggtcccc tctgcctgtc
     3361 tgtgctccag agccactcag gcttctatat cagggcccta tgacaactaa agatagtaaa
     3421 aaactaggca gttcctatgg acccaaccgg gagtccagga ctgcccctcc ctcggcttca
     3481 cgtccgccac tggctctggg ctgtaaccca ccgcttaaca cacatctcta cactaatagg
     3541 gattgaagct gggccaccag ggtacaggac tgtccctgtc acgtgtataa agcttttata
     3601 tgttaggaca aaattaagtt atgagaagtt ctgtgcctgg tgtcggatga tgatctgtaa
     3661 gggatttttc ttctatttat gacttcaggt cgccttcctc aggagggcgg cttagtcacc
     3721 agtgactggg tagatttgta tatttatttt tgtctgttct gtagcttctg tgtccagcat
     3781 cctaaggttt taggatgctt ccctgatttt tgaaataaaa tgtttcctat
//
