LOCUS       NM_001401131            3313 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus kelch-like family member 13 (Klhl13), transcript
            variant 1, mRNA.
ACCESSION   NM_001401131 XM_006257443
VERSION     NM_001401131.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3313)
  AUTHORS   Sumara,I., Quadroni,M., Frei,C., Olma,M.H., Sumara,G., Ricci,R. and
            Peter,M.
  TITLE     A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes,
            regulating mitotic progression and completion of cytokinesis in
            human cells
  JOURNAL   Dev Cell 12 (6), 887-900 (2007)
   PUBMED   17543862
REFERENCE   2  (bases 1 to 3313)
  AUTHORS   Furukawa,M., He,Y.J., Borchers,C. and Xiong,Y.
  TITLE     Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin
            ligases
  JOURNAL   Nat Cell Biol 5 (11), 1001-1007 (2003)
   PUBMED   14528312
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Feb 2, 2022 this sequence version replaced XM_006257443.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ228246.1, SRR26643429.59751.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               JAXUCZ010000021.1  118912172-118912279 c
            109-226             JAXUCZ010000021.1  118908700-118908817 c
            227-298             JAXUCZ010000021.1  118854964-118855035 c
            299-364             JAXUCZ010000021.1  118834349-118834414 c
            365-503             JAXUCZ010000021.1  118796605-118796743 c
            504-636             JAXUCZ010000021.1  118779926-118780058 c
            637-833             JAXUCZ010000021.1  118779180-118779376 c
            834-1629            JAXUCZ010000021.1  118761011-118761806 c
            1630-1743           JAXUCZ010000021.1  118750941-118751054 c
            1744-3313           JAXUCZ010000021.1  118747298-118748867 c
FEATURES             Location/Qualifiers
     source          1..3313
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq34"
     gene            1..3313
                     /gene="Klhl13"
                     /note="kelch-like family member 13"
                     /db_xref="GeneID:313445"
                     /db_xref="RGD:1559646"
     exon            1..108
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            109..226
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            227..298
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..2231
                     /gene="Klhl13"
                     /note="isoform a is encoded by transcript variant 1;
                     kelch-like protein 13"
                     /codon_start=1
                     /product="kelch-like protein 13 isoform a"
                     /protein_id="NP_001388060.1"
                     /db_xref="GeneID:313445"
                     /db_xref="RGD:1559646"
                     /translation="MDILHRGELVAAILRNRRRRQLSLKQADFKDIFKKAAAGSLVEE
                     EDQHLKLCLGSEMGLSSHLQSCKAGSTRIFTSNSHSSVVLQGFDQLRLDGLLCDVTLM
                     PGDTDDAYPVHRVMMASASDYFKAMFTGGMKEQELMCIKLHGVSRVGLRKIIDFIYTA
                     KLSLNMDTLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDK
                     YVNSFVLKNFAALLSTGEFLKLPFERLAFVLSSNSLKRCTELELFKATCRWLRLEEPR
                     MDVAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPFMQPVMQ
                     SDRTAIRSDTTHLVTLGGVLRQQLVVSKELRMYDEKTHEWKSLAPMDAPRYQHGIAVI
                     GNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWIQVASLNEKRTFFHLSALKGFLYA
                     VGGRNAAGELPTVECYNPRTNEWTYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQK
                     ELMCFDPDTDKWIQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYS
                     PILDQWTPIASMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKNEWHKV
                     FDLPESLGGIRACTLTVYPPEENTPSPSRESPLSGP"
     exon            299..364
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            365..503
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            504..636
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            637..833
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            834..1629
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1743
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..3313
                     /gene="Klhl13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggtcaggc ggaggctctg ccgctgcggc cgcagcagct cagctcccat tcccaggcag
       61 cctggaaaag ggactttggc aaataactgg agcggcgttc gggttaggtg ctgaggcctt
      121 cagtccggga ctgagctcca ccgccagcga tctctgagta tccagctctc agactgctgt
      181 gggaagcgac taccgtggga agtctctgtt gctgctactc tactctgtct gctcaacccc
      241 gagaagtgat ggacattctg cacagaggag aattggttgc tgcaatactc cgcaaccgga
      301 gacggaggca attgtcttta aaacaagccg atttcaagga tatattcaaa aaagcagctg
      361 caggatcact tgtggaagag gaagaccagc acttgaaact gtgccttgga agtgaaatgg
      421 gcctctcttc ccatttgcag tcttgcaagg caggaagtac acgcatcttt accagcaaca
      481 gccacagttc tgtggtgtta cagggatttg accagcttcg gcttgatgga ttgctttgtg
      541 acgtgacact gatgccaggt gatacagatg atgcctatcc tgtgcaccga gtcatgatgg
      601 cctctgctag tgactacttc aaagctatgt ttaccggtgg aatgaaagaa caagagttaa
      661 tgtgcattaa gcttcatggc gtgagcagag tgggtctaag gaaaattatt gacttcatct
      721 atactgcaaa gctttctctc aacatggaca cccttcaaga tacactggaa gctgccagct
      781 ttcttcagat tctgccggtt ttagacttct gcaaagtatt tctcatatct ggggtcactt
      841 tggataactg tgttgaagtt ggacggattg ccaacaccta ccatctgaca gaagtggata
      901 aatatgtcaa cagcttcgtc ttaaagaatt ttgctgcatt gctgagtacc ggggagttcc
      961 tgaagcttcc ctttgagcgc cttgcctttg tgctttccag caacagcctt aagcgctgca
     1021 ccgaactcga gctcttcaaa gctacctgcc gttggcttcg cctggaagaa cctagaatgg
     1081 acgttgctgc aaaactaatg aagaacatac gattcccgct gatgacacca caggagctga
     1141 ttaattatgt gcaaacggtg gatttcatga gaactgacaa tacttgtgtc aatttgcttc
     1201 tggaagccag caattaccaa atgatgccgt ttatgcagcc agttatgcag tcagacagga
     1261 ctgccattcg gtctgacacc actcatttgg tcacactcgg aggagtcctg aggcagcagc
     1321 ttgtcgtcag taaagaattg cgcatgtatg atgaaaagac ccacgagtgg aaatctctag
     1381 cccccatgga tgccccaaga taccagcatg gcattgctgt catcggaaat tttctctatg
     1441 ttgttggtgg gcagagtaat tatgacacaa aaggaaaaac ggccgtcgac acagtgttta
     1501 gatttgatcc tcgatacaac aagtggatcc aagttgcatc tttaaatgaa aagcgcacct
     1561 tcttccacct aagtgccctc aaaggatttc tgtatgcagt cggtgggcga aatgcagctg
     1621 gagaactacc tactgtcgag tgttacaatc caagaacaaa tgaatggacc tacgttgcca
     1681 aaatgaatga gcctcactat ggacatgctg gaactgtgta tggaggagtg atgtatattt
     1741 caggaggaat tacccatgac actttccaaa aggaactcat gtgcttcgac cctgatactg
     1801 acaaatggat ccagaaggct ccaatgacca ctgtccgagg cctacactgc atgtgtacag
     1861 taggggatag gctctatgtc attggtggca accatttccg aggaaccagt gattacgatg
     1921 atgtcctgag ctgtgaatac tattcaccta tccttgacca gtggacccca attgcttcca
     1981 tgctaagagg gcagagcgat gttggggtcg ctgtctttga gaataaaatc tatgtggttg
     2041 gtggatattc atggaataat cgctgtatgg tagagatagt gcagaagtat gatccagaga
     2101 aaaatgaatg gcataaggtt ttcgatctgc cagagtccct tggtggtatt cgagcctgta
     2161 cacttacggt ttatccacct gaagaaaata ctccatcacc ttctagagag tcccctcttt
     2221 ctggacccta agatcatcct tacagttaag atgctatatt cctatctttg caatgtgtca
     2281 tgattctctt ctttcccccc ccccttaagt agtatatatg ttagaattag catccagtaa
     2341 ttgatacaga taatggaaaa aaaattgaca ttgatgttac ttgtgctatt tgtatggcct
     2401 agaatgttta taaagtggta acaacccatc ctcgaaatat atcccataga agctgatgtt
     2461 taacattgaa aacaaaaaaa agtattgtct acaagctgtt ccttcagtac tttttaaatg
     2521 ctgtgtactg agtgtaaggt attcatcatc ttacattata agccaagtca gaggtggatt
     2581 gtagtaaacg tacaactgtg cacactaggc ttcaaagtaa agttttcctt tcatctgtaa
     2641 ctgtaaaatg tcaaagggag gcagcctgct ccaacaggaa acaatacaca aacggttgtc
     2701 aactcgcatg agctacctcc ctcttttcat acagtatttt tgacacatct gtcaacccac
     2761 ccgaatatgt gggtgcattg agaacacacc aagtttctaa gacacacagg agaaataact
     2821 gaaattcacc aacactagtt agggggaaag catgacccct ctgcttctaa gaattggttt
     2881 ggggtttttt aagtgtgtat agataaacac acacatactt ctatcaaaca caaattttta
     2941 aaaattgagt gtcaggtcaa ataaatgtga aattaaaata aattcttcga aaaagcagct
     3001 tccatgaaca atggggattc agtatgcaca cattaaatgc atatatttgg aaccatactg
     3061 aatttaggtg gataagggct agaaattttg agcaactaaa tttatcactt gaccaaattt
     3121 tatcttaaag aattacattc tctttttctc ctttgctgtt gaggtaactt acctgttctg
     3181 tgtattctgt attctgtaca ctcttggttc atgaggttat ttagcacaaa gtgtaacagc
     3241 ttcgcctggg aagctgcttt tgctctatga tgtccatggt ttccctttta ttcaataaaa
     3301 acatttaatg tca
//
