LOCUS       NM_001414927            2216 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus kelch domain containing 1 (Klhdc1), transcript
            variant 1, mRNA.
ACCESSION   NM_001414927 XM_006240169
VERSION     NM_001414927.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Dec 15, 2022 this sequence version replaced XM_006240169.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.23057.1,
                                           SRR26643295.25520.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-148               JAXUCZ010000006.1  93448808-93448955
            149-219             JAXUCZ010000006.1  93462994-93463064
            220-337             JAXUCZ010000006.1  93463684-93463801
            338-456             JAXUCZ010000006.1  93464210-93464328
            457-535             JAXUCZ010000006.1  93465644-93465722
            536-619             JAXUCZ010000006.1  93468585-93468668
            620-703             JAXUCZ010000006.1  93470561-93470644
            704-762             JAXUCZ010000006.1  93471104-93471162
            763-875             JAXUCZ010000006.1  93474181-93474293
            876-948             JAXUCZ010000006.1  93477952-93478024
            949-1033            JAXUCZ010000006.1  93482497-93482581
            1034-1086           JAXUCZ010000006.1  93485812-93485864
            1087-2216           JAXUCZ010000006.1  93500259-93501388
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..2216
                     /gene="Klhdc1"
                     /note="kelch domain containing 1"
                     /db_xref="GeneID:314190"
                     /db_xref="RGD:1308211"
     exon            1..148
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1273
                     /gene="Klhdc1"
                     /note="isoform 1 is encoded by transcript variant 1; kelch
                     domain-containing protein 1"
                     /codon_start=1
                     /product="kelch domain-containing protein 1 isoform 1"
                     /protein_id="NP_001401856.1"
                     /db_xref="GeneID:314190"
                     /db_xref="RGD:1308211"
                     /translation="MADSQAFCVAEERSGHCAVVDGHFLYVWGGYVSIEDNEVYLPND
                     EIWTYDVDSGLWKMHLMEGELPPSMSGSCGACINGRLYVFGGYDDKGYSNRLYFVDLR
                     TRDGTYIWEKITKFEGQPPTPRDKLSCWVYKDRLIYFGGYGYRRHSELQECFDVHDAS
                     WEEQIFWGWHNDVHVFDTKTRTWSQPEIKGGVPPQPRAAHSCAVLGNKGYVFGGRVLQ
                     TRMNDLHYLNLDTWVWSGRISVNGESPKHRSWHTLTAIADDKLFLFGGLSADNIPLSD
                     GWIHNIITNCWKQLRHLPYTRPRLWHTACLGKENEIMVFGGSKDNLLFLDTGHCNDLL
                     IFQTQPYSLLRSCLDCIGKNAIILKSQISLLPPKLLQQVFQKITFWTAANYRKEQRIQ
                     KGETENKQPRVSSC"
     exon            149..219
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            220..337
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            338..456
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            457..535
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            536..619
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            620..703
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            704..762
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..875
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            876..948
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1033
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1086
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..2216
                     /gene="Klhdc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttccgttcg cgcgtgcgag ccggcgcgga gctggctggg cccggagggc ggatggcgga
       61 ctcgcaggcg ttctgcgtgg cggaggagcg cagcggccac tgcgctgtgg tggacggaca
      121 cttcctctac gtgtgggggg gctacgtgtc tattgaggac aatgaggtgt atttgccgaa
      181 cgatgagatt tggacctatg atgttgatag tgggctgtgg aaaatgcacc tgatggaagg
      241 ggagctccct ccctccatgt ccggaagctg cggggcatgc atcaacggga ggctctatgt
      301 ttttggaggc tatgacgaca aaggatacag caaccgactt tactttgttg atttacgcac
      361 aagagatgga acttacatct gggaaaaaat caccaagttt gagggacagc cacccacacc
      421 acgtgacaag ctctcctgct gggtgtataa agacagatta atatatttcg gtggttatgg
      481 gtacaggagg cacagtgagc ttcaagaatg ttttgatgtc catgatgcat cttgggaaga
      541 gcagatattc tgggggtggc acaatgacgt ccatgtgttt gacacaaaaa cgaggacttg
      601 gtctcaacca gaaattaaag gtggagttcc accacagcca cgagccgcgc attcatgtgc
      661 agttctggga aataagggtt atgtctttgg cggacgcgtt ttgcaaacca ggatgaatga
      721 cttacactat ctgaacctag atacctgggt ctggtctgga aggatttctg ttaatggaga
      781 aagccccaaa caccggtcat ggcacacttt aacagcaatc gcggacgata agcttttcct
      841 atttggtgga ctaagtgcag ataatattcc actaagtgat ggctggattc ataatataat
      901 aacaaactgt tggaaacaac ttagacattt accttacacc aggcccaggt tatggcacac
      961 agcctgtttg ggaaaagaaa acgaaataat ggtatttggt gggagcaaag acaacttact
     1021 tttcttggat acaggtcact gtaatgattt attgatcttt caaacacagc cctattcact
     1081 gctcaggtca tgtcttgact gcattgggaa aaatgcgatc attttaaaaa gtcaaatatc
     1141 tttattacct cctaaacttc tgcagcaagt cttccaaaaa ataacatttt ggactgcagc
     1201 caattaccga aaggagcaaa gaatccaaaa gggagagaca gaaaataagc agcctagggt
     1261 cagtagctgc tgagccctct gagcccagtg tgtgagcgtg tttgcatcag accacacagt
     1321 ccacctctgc tgaagtgaag gctgccttgc aggatacaag tgtttgccaa tgtgattcca
     1381 tggtacaaga tgtatggaaa taagacgtag ttaaagattt atctgtgtgt ttgtaaactg
     1441 attttcttat aaaagaataa gtgttctttc tgggaataag tacagtaaca acagatctta
     1501 actcagtgtg tactcttttc ttgagagatt atacagattt gaagaacaga cattgctcta
     1561 agatcttcag aaatcttgta acacaactgt ggatatagat atggaaatat tcctagttag
     1621 cttccatata agatcaccta agtggctcct taaatagcac catcagacct ttccctccac
     1681 gttgttgagc aggcaagctc attcagctac ttcaggcttt gccctgctag gaccacgtgg
     1741 tggaggttgg tttgcctaca gctttgaaat attggggtgt gggttattag tagctttgag
     1801 acatgtaaaa tacacttcgc cttgggaaac gtgttcctaa cgtactatgt gtaagtgacg
     1861 tggcgtggta atctggtgtt tttgactctg tgacctcccc gcaccctgct tgggctaccg
     1921 tgctctacac acttgatgct gctccagcac cagccatcca gaaagggaga ccacactgtt
     1981 ccattcctca agatggcaca cagccatttg agacaccttt cttcatgttg tttgtcgttt
     2041 cctgccatta caattaatta ctaaagggtt caatagtatg acattacccc ctcactgtta
     2101 ctacgtaagt tatttctaaa ctttaaaatg ctgggagagt atatttctgt attgtatata
     2161 gtttatagtg agaattgtac ttcattaaac tggagatata ttttatacac gctgta
//
