LOCUS       XM_017602262           10634 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus KLF transcription factor 8 (Klf8),
            transcript variant X1, mRNA.
ACCESSION   XM_017602262
VERSION     XM_017602262.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_017602262.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10634
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..10634
                     /gene="Klf8"
                     /note="KLF transcription factor 8; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     ESTs, 7 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 8 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:302582"
                     /db_xref="RGD:1565831"
     CDS             78..1412
                     /gene="Klf8"
                     /codon_start=1
                     /product="Krueppel-like factor 8 isoform X1"
                     /protein_id="XP_017457751.1"
                     /db_xref="GeneID:302582"
                     /db_xref="RGD:1565831"
                     /translation="MYSICSDCLARAPGFDPRVRYTSGAASLEKTGRWGTKEEKAKAR
                     YQARCQTWAGARGTAALRSALEYESLRGLRELRTLQESSARGIGDMDKFINNMDVRIK
                     TESDSMEVFKQVTGPVPTRDPSVRGDRRNMTSPPFLAASPMENPALFNDIKIEPPEEL
                     LESDFNTPQVEPVDLSFHKPKAPLQPASMLQAPIRPPKPPTAPQAIMVSTSADTVTSA
                     AIPTVLTPGSILASSQGTGGQPILHVIHTIPSVSLPNKMSGLKTIPLVVQSLPMVYTS
                     LPADGSPAAITVPLIGGDGKSAGSVKVDPASMCPLEFPSDSDESAIESGSSALQSLQG
                     FHHEPATMVHMQGEESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCT
                     WDGCSWKFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRHDTM"
ORIGIN      
        1 taaggaactc caccctaggt ggagtcctcg tggtagtcgc acctctcttc tgggcctagt
       61 ctgacacaga aagagctatg tactccatct gctcagattg cctggcgaga gcaccaggct
      121 ttgacccgcg ggtgcggtat accagtgggg cagccagcct ggagaaaaca gggaggtggg
      181 ggaccaagga agagaaggct aaagcgcgtt accaggcgcg ctgtcagaca tgggcgggtg
      241 caaggggaac agctgccttg agatcagctc tggagtatga gtctctgaga ggactgcgtg
      301 agctccggac acttcaggag tcctcggcta gaggcatagg cgatatggat aaattcataa
      361 acaacatgga tgtccgaatt aaaacagaaa gtgattcgat ggaggtattc aaacaggtca
      421 ctggccctgt tccaaccaga gatccttctg tgagaggaga cagaaggaat atgacttctc
      481 caccattcct ggctgccagc ccaatggaga acccagctct gtttaatgac atcaagattg
      541 agcctccaga agagctcctg gagagtgatt tcaacacgcc ccaggtggaa ccagttgatc
      601 tctcctttca caaaccgaag gctccgctcc agcctgctag catgctgcaa gctccaatcc
      661 gccctcccaa gccaccgact gcacctcaag ccattatggt gtctacttca gctgacacag
      721 tcacttcagc agccattcct actgttctca ctccaggctc tatcctggcc tcctctcagg
      781 ggaccggtgg ccagccgatt ttacatgtga tccacaccat cccctcagtc agtttgccaa
      841 ataagatgag tggactaaag acaatcccgc tggtggttca gtctttgccg atggtctata
      901 caagtttgcc tgcagatggg agccctgcag ccattactgt cccacttatt ggaggagatg
      961 gcaaaagtgc tggatcagtc aaagttgacc ccgcctccat gtgtccactg gagtttccaa
     1021 gtgatagtga tgagagtgca attgagagtg gctcttcagc cttacagagt ctgcagggat
     1081 ttcatcatga accagcgaca atggtccaca tgcagggaga agaatctctt gacttaaaga
     1141 gaagacggat tcatcagtgt gactttgcag gatgcagcaa agtgtacacc aaaagctctc
     1201 acctgaaagc tcaccgcaga atccatacag gagagaagcc ttacaagtgc acctgggacg
     1261 gctgttcctg gaaatttgct cgctcggatg agcttactcg ccatttccgt aagcacacag
     1321 gcatcaagcc gttccggtgc acagactgca accgcagttt ttctcgatct gaccacttgt
     1381 ccctccaccg ccggcgtcat gacaccatgt gaatatcaca ggcgacagca gacgcgctgc
     1441 accagtctcc taagtgtgtg ctgaagttgt aactatgttt gcctctttga ctacaacttg
     1501 ccccacgtga ttggggttcg aacagcttac tgagccaggt taatgagact ggaaaacaag
     1561 ttagctgatc tcccatgcgg ctcttcatat tccgctttca cctctccact gtccagactt
     1621 cagtttttgc aacctcttcc tgggttgaat tctagtgcgg cgcccatggc tgccctccct
     1681 gatccctcat gctatattat agacattttt cctacaataa caaacaaaac aggaatcaaa
     1741 ctcaaggctg tgaacaaaca tccgctgctc cccccacccc cagttttctc ttgttttcaa
     1801 aaaccagtac ttaatgtcac ttagcaatgt cctaaaatga ggggtatttt caaagttgta
     1861 gctacaaggg gcataacagt agagttggtt gatcaaattt acagaaactt gagtctgaaa
     1921 tacagtctca agctaaccat gaaggttttg tagatccagt tttacttgtt cttaacagtt
     1981 tggtttacag gcagtgccag ccctcctttt gaagttcatc aaaagcaatg aagggattcc
     2041 ttgacctcct tttcctcctc atgctccttt agagtgaaag gttttatggc acaattccat
     2101 tctttttagg ttatgtttgg acaaatattc aaagcacaga aagaaagatc agtagggaga
     2161 aatattctag gaaaatatgt gggcaatgac aggcaagagc agacctggga gcaccctgtg
     2221 aacaattaca tggataaggt gttagaactg ctgttagtcc caaacctcat tcagagggca
     2281 gcctgttgag acagcacttt cgatgggcta cactgtactg tttattcttt tgtttacata
     2341 aaacaaccat tcagcgtatt acctgatgag aaattgcaca ctgagcacgt tatagagagg
     2401 tgaggggttg cactaaagaa ttttgtttac ttcatgccat tttgggcatt cattcttccg
     2461 cttctaatgg gaaggaaagg ttttctttct gacactaaca tatagaaagc attttgatgt
     2521 tttacaactg ttattaatac ccaagccatt tattttattt agacataaca gcaggatgca
     2581 taatatacat ttggttgccc agtcagactg ttcataatat tctctggggc ataaaacctt
     2641 ctgttcctgg ccctggacct catatctacc tcctcgtggc atatttcctc tcctggggag
     2701 aaaggagagg ggctttgtat tggtaggatt ggacgcagcc tctcgcctaa aggttttctt
     2761 catacgaaac ctttatttct tggcagatat tcaaaatgtt ctggcttgaa cactttaggt
     2821 tactacctcc tgtggctgta ctaactaaaa cctagaattc taccattcag aaggggtcct
     2881 gtctacttct acccatccct cacgttttac agatgaggca aatacgggtc agattctttc
     2941 tccagataat tccttgaggc cttatagacc tgtatactcc ttctcccagg gatcacacta
     3001 gtaaaccaaa ttaaagaaaa aaagttatgt gattggttgc aatatttgtc caattttatg
     3061 ttatacttca gaaaacttaa gtcacttaaa attcatatat atttggtgac aaagtaagta
     3121 gggcgcgctt atggtcatgg ccacttaaca ccgggcacat agtgtttcaa gtctcatttt
     3181 tgataactct agatttgttt taatttacct tgtttcagtg tctttccaga gcataaattc
     3241 tccgtaagtt aaggcctgca tgtacttttc aacataacat gtaggtttta ttattaccac
     3301 tttcgtaagg gatttttcct gactctgggg gtacaagttc caggctgtat actaattaag
     3361 cacccatcaa catctagggc tagcctactg atggggacca cagtgtaaga cagatgtatt
     3421 actaccacac gtgggcttat gcttgcaatc gagtagttgg tacaatatta tagaacagag
     3481 tccaaagggt tgtgtccttt tgttccactt tggatcctaa atttgttttc cagagtttgg
     3541 aattggcaca tgccccttag acttcaggat atggagacat gtttattaag gagcactatg
     3601 aaattatagt actcataagg gtgatcaaat gaggatcccg gatactgatg ttcctagcat
     3661 ctctgagcct ttattcacgt atgtttctgc agagtcataa tagactctgc aaatgctttg
     3721 tacattgtct ttagccaaga accaattcta accatattct ctttgctctt tttgtcccca
     3781 aatggcaaaa atctttccag ttacaaacat aatctttaca actgtgtcat gattaagaga
     3841 acttcgcaga gtaaaatgaa cacaaacaca gtacagtgca gaattactgc actaaaagca
     3901 cataaaagtt tgctagtcag tggaatagga aggaaaccat tgcatctctc ttggttaaca
     3961 tctgagattt aactaagtgt aatgggctta caatgcccaa agactgctag gatgacattt
     4021 gcctaggata gggacatttt gtaaggatgg ataatattca ggagtttatt gtagtggagt
     4081 ttctccttca gtagacatct ggcaactgaa cagaatcatt gagaattgcc attgtaaagt
     4141 gtaagaaatg taaactggtt tgatggatta gtggagttca ttatgtacaa acccacaaat
     4201 gtctgtagag aatttctttt taaataaact ttatatgttg tagctctttt ttgagatttt
     4261 caggagaatg tgaaggtaga acagagttcc tgtttactcc acattttaca ttagtttggt
     4321 acacttctta caattaggga tgcattaata ttaactgcaa tccatgcttt agttgactac
     4381 cttggctttt atctgctgtt ctttttttct gttttaatat ctccttcaaa atacaacatt
     4441 gtattaataa tcacagctcc ttagtctcct cattgtgata gtttcttgga gttctttgtt
     4501 ctcaaggacc ttggagtatg ttcttcagtt gtgatttgat actcttctca tcaaaatttt
     4561 ctcataaaaa atctaggtta atgaaagtca ggcatggtga catatatttt ccttttaatc
     4621 ccagcacttg ggaggcaaag gcaggtggat ttctgagttc gagactagcc tggcctacag
     4681 agtgagttcc aggacagcca gggctacaca gagaaaccct gtctcagaaa acattaaccc
     4741 aaccttcata ggttaatgga ttttggtcca aacaaccaca tgagtgagtt actattttta
     4801 taatgtcata tttctgtgag ttattcttca tattatcctt agtcacatga ctaagatagt
     4861 gtatatgaga tttctcccct ataccctttt tcctatcata ctgaaatctt tggaaggaag
     4921 ttaccatgct cagtccacac atagagaagt ggtgagctat gcacatgtac ttgagagcaa
     4981 gtgtgcatat gattattttg gaattcttct gcatgggagc tttgcctcct ctccatttgt
     5041 ttacttgcat aattgtttat tttttcaaca tggatcactg atatttattt tatagttttt
     5101 cttataatcc aatgcaactt ttatttttgt tgcccaaatt gtagttttaa atgtttggag
     5161 tgatttttaa ttgactctga agtctttttt ttttttacaa accccatctt tttttcagca
     5221 tgtagttaat ttttggtgtt gcaagatgtt ccaggcttat cttgcttttg ttttatggag
     5281 gacaattcta taatcaggca ttttgtcaat aagttctaag ttcttttact aaagaatttt
     5341 atcagaaacc aagatataga tactatatat gtttgctatt ttggggatat tatttcttca
     5401 agtccttctc agtcagtaga acaaaaaata tatgcatata ttaagttttt aatatatgca
     5461 catgtctata aacatttcca cataatcatc tttgtgatga tttatgagtt tatattatgt
     5521 cctcaatcct tatctgtata tctttccatt ctatcagcaa gaaccatagc tccatcttct
     5581 gccatttatt aattgatgac atccatgtta atgctaatga agtacatatt aacagtgtct
     5641 tacgtgttat gctgtatacc cacaagaaaa atcaatcaac tagaacccgg tgcttatata
     5701 catgacagga acctttttag aacttcaact ctgaaacaaa atgatctaca agattcttga
     5761 attagcgata atctgtattc tcaattctat cctagtcccc caatgctttc tcatccatgt
     5821 aacaaaccat cggtgattga cctagccttg cataagacaa gagaacatgt tgatcctcca
     5881 tagtatgtta attcctatat aaaggatcaa agagaaagca gctgcctggg tctaatttga
     5941 agaaacactt agcactgtct ttttctctgc tgaaaatgga tctctaacaa ctgggaagta
     6001 ctctgatttg cttctcttct gtattttccc cagtttttag gcaagtcata tcacctctct
     6061 gtgcctctat taacccatct cgaaatgggg atccacatat ctacctcaca ggagtgttgt
     6121 gaggcttatt aatagatgtt ttaaaaatgt aatctctaaa tgagtaagaa agtattataa
     6181 tcattgctat gatgataatt agagtaccct atatgcatcc taaggaaaag gagattagcc
     6241 tcattgttag taaacagcta aaattaagtc aataaaagat caatgaagag tggccactgg
     6301 aagcaagatt atttgttctg ttaccctcac tttccctgta ttctctaagt aggattatca
     6361 actgtctgtt tccagactca aaacatatga ggttctaaaa cagtaggagg caaagtacat
     6421 tgtcattttc aaattctgtt ttttctccct ttcttactct ggttggacta cattacgtag
     6481 aactttgtca gaagcacaaa gacaatttct caaagggttt cagtctttga tcagttctgt
     6541 tctatcagtt aaaatttctc tttctgcgcg tactgtacat tgaacagtca aggtaggagg
     6601 ggagtgggtg ggatggttgg gttgggcgtg gactgtgaga gaagggaaat tactttccat
     6661 ttcactttcc atttcttttt ttctggtggc gggtttgggg caagggaaga gatactattt
     6721 tgttaacaaa ttcttcttcc cttccagtag atgtttcctg gggtcagtac aaatagctgt
     6781 gttggacctt acttttataa ctatgttgta tacagtgttg ttttcattgt atttctgaat
     6841 aaagggggaa gaaagtctct agtgttggcc atccctgttt ttgacaggag gtcacagcag
     6901 gagagcagca cccgaagctg actcttttta tggtggggaa aggagcctgc agtgaaggga
     6961 tttattggat ttttgtcatt ctttaaagaa gttataaagc agtatattac gcattagtct
     7021 ctatgactct tctgtttgtg cctccttatt ttaatagtgc tttagagcag cacctatttt
     7081 cactccattt tatacttgtt cctgttgagg tgtggtgttg agcaatctct catatacaag
     7141 tcttcatgta cctgaagaga attgcctcag taagcatggc tatccagagc ttactctgat
     7201 gtagctcagt ggggcactcc cattgcagct tccaggccag gctgtgtgct tgagtactaa
     7261 gcaatcttgt tctgtctgat tactgtactt ttttaataat aaaaatattt taaaccagaa
     7321 accatgggtt ttgtgttaga tttatcttct cattgtattt cttcatcata aagcaaatag
     7381 cttgttttct tttcgaaact gactaaagtt gttgcctaaa ggtggtggtt ccttccttca
     7441 atcccaacac ttagaggcag agacaggcag acctctgagt tgaaggccag cctggtctat
     7501 agcctaagtt tcaggatagc cagggctact acacagagaa tctctgtcac aaaaagcaaa
     7561 caaagtcgtg atggaagcac tgtatagtac tgtgaggcca caaaggaagt cagactatct
     7621 taaaacatgg cttttcctgc ttagggatgg gttgccctcc caattgttgc tggtacaatc
     7681 agacataatc atgaatagga cctgatgaaa attgcatatg ctgtgttttt gtatttccta
     7741 tataggatcc ctcaagattt tggcgggggg tggggagatg gtggagggct atagacgtta
     7801 cgtaggtttt cctgcccggg acctgttgtc tttgccattt tagtgtttta ggaggaagtc
     7861 aataggtaaa ggagggtatt tggacagttt tcaacttaca agacatctca atacaacagg
     7921 agttctgagc agacccccca gaagaagtct catccaaaat gttggtattg caaagaaaca
     7981 ttaggaggag ggtaaaagac tgtgaaagag attgaaacca ggaatggctg ttccctgggc
     8041 tgtcagaatg gggttttcac tacagatcct aaacacaaca attcacagag cttacagatt
     8101 tcccagcact atttattttg tgagaagcaa atagtattat gaaagtatca ttaaacagag
     8161 ctttataaaa tgacactggg cagccattca ggtaacagga tacgtgaact ttgagcgcct
     8221 ccaccggctc atcagaagaa acacctgtaa tgagagagtg aatgaccact gttttgtgcc
     8281 tggtggctta ccacaggtga cagatgacta ttggacagtt tcctcatttg catttccatt
     8341 ctgtcacctg gtagtcgtgg aggtcattcc ttaacatcca acagcttcca ccaatgtaag
     8401 catgcacttg tcccaccttc agaacactga ttcacagcta ccgaacctgt gcttccaaaa
     8461 tggaaatctc ttacggcctc caatgaagct ttttaccttt cccagttttt gcattgagac
     8521 tgattgtcat tacattgtca ggggtggatc agaggtgact catctctgcc tctgtgctgc
     8581 cgctgacacc agtacctaca acagctccct tgtatcctac cagatccctg ctgctttcag
     8641 tgtgtaaagg tttaaaggtt tctcaacctt ccaccatctc cacaactttt tttttttaag
     8701 gtttcaagtc tttgtaagtg ctctttgttg ctggctgcct agtagagaaa tggcaagttt
     8761 aggtgtctag gagaaacatt ttttcttcaa tctagattat cattaagact ttgggaagga
     8821 gtgaataaaa tttatatctg tagttgaagg aatagagtca gtccacatga atgcactctt
     8881 ctgactgaaa agaggacatt cattgctcag atcttctgaa gccaccacta ctctgaccac
     8941 atggtgttcc ccttcctaag aagtgacccc catcttattt caatgagagt catgtcatcc
     9001 ctcttcattt taaaaatagt ttttactatt gaatgtataa ataaccccat cattcctccc
     9061 ctttcctttc cccaaactct cctgtatatt cctccttgct ttcaaatttg ggctctcatt
     9121 ttgttaacta ttattattat atacatacat atctctaaat acagtctgct cagtccatag
     9181 aatattactt gcatgtatat gtttttgggt ctgaccgttt ggtattggct aaccaactaa
     9241 tgtatttgtt ccctgaagaa gactgttttt tcctgctcac agcactcctt agttgcctgt
     9301 agttctttgt ctagggttga ggcgtcatgg cttcccctgc cctccacatt agcatgttca
     9361 tgccttgttc aaaacctctt cagactttac agatgtggct tccgactttt ctagaggata
     9421 caatctcaaa acaaatgctc tgttgtctgg ctcttatgat ctctcccctt ccctgtatca
     9481 atgttacctg acccttaggt acaggaattg tattataaat atatctattg ggactgcact
     9541 ccacaacttg gcattttgat tggttgtagc tttctacagt ggtctccatc tgttgcaaag
     9601 agattttttt ccttgatgaa cagtgaaaac tatacttcct tgtatgtata aggatagatg
     9661 tatttatgac ttatgctggt ttattaaagg aatggttgta ggttctcttc cataatccat
     9721 gacttcattt gctagttttc cagtatcagg tccgagctcc ctattgttga gcagggctta
     9781 aatctagtta gagatttaac tgttgtttcc aaggtacaag tgccactact gaaacttggt
     9841 gttatgcagc catgctggtg aatgcatagg aatcacagcc acagctgggt agggctgttg
     9901 gttgctttcc tcctttggaa acttccatgg ctccttttta ctgagagcca gtactccggg
     9961 aggaggcttt caggtagttc cagcctaggg gctgtcttct actttaacaa taatcatatc
    10021 actcctctca atgaatgcaa gtacaacctt tacttttctt gtttatgtac ctgaaacatg
    10081 tataggtttg taccttgatt cctttactca gaattatgtt tgtgaaatcc atccatggtg
    10141 gtatatgtaa ctctagtaca tttatttttg ttactgtgag atatttcatt atataactac
    10201 aatgaaataa gttcgtatct actcaatata tactatccca aacaggttat ggagttcccc
    10261 gtacgtacac tgaggtgttt ggtttttcct tacactattt caaatcttaa atgtaaaaat
    10321 acttaaagaa acacaacttt ggtcaatgtt ctcctaaatg tcttttgatg tccatttgta
    10381 agaatttctc ttaaggaaac tatctaggga agggaattct ggtacatagg acaattgatt
    10441 tttaagctta gcttgtcaat gtaaaatatt tttcaatgta attttgccaa tttatttact
    10501 tataatgtgt gaggctttaa atcacagctc tgataatgta tgtcatcatt tgttttttta
    10561 agggattcct gggaacagaa gatgatgcat gtagcattac tcatgctagc tgtataataa
    10621 agattggagc cagg
//
