LOCUS       NM_001109147             602 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus KLF transcription factor 13 (Klf13), mRNA.
ACCESSION   NM_001109147 XM_001058300 XM_574467
VERSION     NM_001109147.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Gu M, Wang J, Wang Y, Xu Y, Zhang Y, Wu W and Liao S.
  TITLE     MiR-147b inhibits cell viability and promotes apoptosis of rat H9c2
            cardiomyocytes via down-regulating KLF13 expression
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 50 (3), 288-297 (2018)
   PUBMED   29377979
  REMARK    GeneRIF: Data show that Kruppel-like factor 1 (KLF13) was a
            downstream target of miR-147b.
REFERENCE   2  (bases 1 to 602)
  AUTHORS   Bayoumi AS, Park KM, Wang Y, Teoh JP, Aonuma T, Tang Y, Su H,
            Weintraub NL and Kim IM.
  TITLE     A carvedilol-responsive microRNA, miR-125b-5p protects the heart
            from acute myocardial infarction by repressing pro-apoptotic bak1
            and klf13 in cardiomyocytes
  JOURNAL   J Mol Cell Cardiol 114, 72-82 (2018)
   PUBMED   29122578
  REMARK    GeneRIF: the improvement of cardiac function and structure elicited
            by miR-125b-5p is in part attributed to repression of the
            pro-apoptotic genes Bak1 and Klf13 in cardiomyocytes.
REFERENCE   3  (bases 1 to 602)
  AUTHORS   Gordon AR, Outram SV, Keramatipour M, Goddard CA, Colledge WH,
            Metcalfe JC, Hager-Theodorides AL, Crompton T and Kemp PR.
  TITLE     Splenomegaly and modified erythropoiesis in KLF13-/- mice
  JOURNAL   J Biol Chem 283 (18), 11897-11904 (2008)
   PUBMED   18285334
REFERENCE   4  (bases 1 to 602)
  AUTHORS   Martin KM, Cooper WN, Metcalfe JC and Kemp PR.
  TITLE     Mouse BTEB3, a new member of the basic transcription element
            binding protein (BTEB) family, activates expression from GC-rich
            minimal promoter regions
  JOURNAL   Biochem J 345 Pt 3 (Pt 3), 529-533 (2000)
   PUBMED   10642511
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473980.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001058300.1, XM_574467.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132294,
                              SAMN16676809 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..602
                     /gene="Klf13"
                     /gene_synonym="RGD1565099"
                     /note="KLF transcription factor 13"
                     /db_xref="GeneID:499171"
                     /db_xref="RGD:1565099"
     exon            1..201
                     /gene="Klf13"
                     /gene_synonym="RGD1565099"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..491
                     /gene="Klf13"
                     /gene_synonym="RGD1565099"
                     /note="Kruppel-like factor 13"
                     /codon_start=1
                     /product="Krueppel-like factor 13"
                     /protein_id="NP_001102617.1"
                     /db_xref="GeneID:499171"
                     /db_xref="RGD:1565099"
                     /translation="MSGHNSTFPGTPGLPGSLLCLTVGHFIYPCPNREPGERPFACSW
                     QECNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQR
                     RGGGSRTGSLSDYSRSDASSPTISPASSP"
     exon            202..602
                     /gene="Klf13"
                     /gene_synonym="RGD1565099"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcttgcaggc agcctgggtc agccgcacct ggccgggctc tcctgtccat acgcctggct
       61 gttgatggga atgtccctgt gggaatggcc agcccatgag tggacacaac agtacattcc
      121 cagggactcc tggtttgcca gggtctctac tctgtctcac tgtcggtcac tttatatatc
      181 cttgccccaa cagagagcct ggtgagaggc cctttgcctg cagctggcag gagtgcaaca
      241 agaagttcgc gcgctccgac gagctggccc gacactatcg cacgcacacg ggcgagaaga
      301 agttcagctg ccccatctgc gagaagcgct tcatgcggag cgaccacctg acgaagcacg
      361 cacgccgcca cgccaacttc catcccggca tgctgcagcg gcgtggcggg ggctcgagga
      421 ccggctcgct cagcgactac agccgctcgg atgccagcag ccccaccatc agcccggcca
      481 gctcaccctg agcacccgca cccggaccgc gcctcctcgc ccctttggta ataggaaagc
      541 tgagcgaact tgagaagtcc acagcaaaac agttttcttc acctcaggtg tcaattttta
      601 ac
//
