LOCUS       NM_001048215            3640 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus kirre like nephrin family adhesion molecule 3
            (Kirrel3), mRNA.
ACCESSION   NM_001048215 XM_001057195 XM_001057259 XM_235986
VERSION     NM_001048215.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3640)
  AUTHORS   Martin,E.A., Muralidhar,S., Wang,Z., Cervantes,D.C., Basu,R.,
            Taylor,M.R., Hunter,J., Cutforth,T., Wilke,S.A., Ghosh,A. and
            Williams,M.E.
  TITLE     The intellectual disability gene Kirrel3 regulates target-specific
            mossy fiber synapse development in the hippocampus
  JOURNAL   Elife 4, e09395 (2015)
   PUBMED   26575286
  REMARK    Erratum:[Elife. 2016 Jun 16;5:e18706. doi: 10.7554/eLife.18706.
            PMID: 27310701]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3640)
  AUTHORS   Liu,Y.F., Sowell,S.M., Luo,Y., Chaubey,A., Cameron,R.S., Kim,H.G.
            and Srivastava,A.K.
  TITLE     Autism and Intellectual Disability-Associated KIRREL3 Interacts
            with Neuronal Proteins MAP1B and MYO16 with Potential Roles in
            Neurodevelopment
  JOURNAL   PLoS One 10 (4), e0123106 (2015)
   PUBMED   25902260
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3640)
  AUTHORS   Prince,J.E., Brignall,A.C., Cutforth,T., Shen,K. and Cloutier,J.F.
  TITLE     Kirrel3 is required for the coalescence of vomeronasal sensory
            neuron axons into glomeruli and for male-male aggression
  JOURNAL   Development 140 (11), 2398-2408 (2013)
   PUBMED   23637329
REFERENCE   4  (bases 1 to 3640)
  AUTHORS   Nishida,K., Nakayama,K., Yoshimura,S. and Murakami,F.
  TITLE     Role of Neph2 in pontine nuclei formation in the developing
            hindbrain
  JOURNAL   Mol Cell Neurosci 46 (3), 662-670 (2011)
   PUBMED   21241806
REFERENCE   5  (bases 1 to 3640)
  AUTHORS   Gerke,P., Benzing,T., Hohne,M., Kispert,A., Frotscher,M., Walz,G.
            and Kretz,O.
  TITLE     Neuronal expression and interaction with the synaptic protein CASK
            suggest a role for Neph1 and Neph2 in synaptogenesis
  JOURNAL   J Comp Neurol 498 (4), 466-475 (2006)
   PUBMED   16874800
REFERENCE   6  (bases 1 to 3640)
  AUTHORS   Ueno,H., Sakita-Ishikawa,M., Morikawa,Y., Nakano,T., Kitamura,T.
            and Saito,M.
  TITLE     A stromal cell-derived membrane protein that supports hematopoietic
            stem cells
  JOURNAL   Nat Immunol 4 (5), 457-463 (2003)
   PUBMED   12665856
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ902828.1.
            
            [WARNING] On Oct 8, 2024 this sequence was replaced by
            NM_001048215.2.
            
            On or before Sep 23, 2006 this sequence version replaced
            XM_235986.4, XM_001057259.1, XM_001057195.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ902828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3640
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q21"
     gene            1..3640
                     /gene="Kirrel3"
                     /note="kirre like nephrin family adhesion molecule 3"
                     /db_xref="GeneID:315546"
                     /db_xref="RGD:1311382"
     exon            1..359
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     CDS             305..2605
                     /gene="Kirrel3"
                     /note="kin of IRRE-like protein 3; kin of IRRE like 3"
                     /codon_start=1
                     /product="kin of IRRE-like protein 3 precursor"
                     /protein_id="NP_001041680.1"
                     /db_xref="GeneID:315546"
                     /db_xref="RGD:1311382"
                     /translation="MRPFQLDLLFLCFFLFSQELGLQRRGCCLVLGYMAKDKFRRMNE
                     GQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVV
                     GNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPIILGGPVISL
                     RAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGD
                     VENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNIVTFHCSAKAN
                     PAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFG
                     PRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQED
                     AGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDR
                     IAWSWKENVLESGTSGRYTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSD
                     TEIIRLKEQESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRNLKGVVSAKNDIR
                     VEIVHKEPASGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNG
                     YYSVNTFKEHHSTPTISLSSCQPDLRPTGKQRVPTGMSFTNIYSTLSGQGRLYDYGQR
                     FVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASAS
                     SSHHSQSSSQNSDPSRPLQRRMQTHV"
     exon            360..437
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            438..587
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            588..737
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            738..895
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1046
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1152
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1301
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1429
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1556
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1657
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1856
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1857..1964
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2074
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2161
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
     exon            2162..3636
                     /gene="Kirrel3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccgtgtgc ctgggatact aagagccaga gaatggatct gctccgagtg gggacattgc
       61 tgaggatccc ggcttcccga ggtggctgaa aacaagcatt tggtttcggc tgcctgcaga
      121 tacctggagt cacagcgaga cctaagcgga ccggaggagg gacagaccga ctgacagata
      181 gatggtcggc gcgaacccag gaggaccggc ggcggaggct gagcaccgcg agcccagccg
      241 ccgctcttga agagaaacta actgctcgcc caagttgccc cgccggctgc ccgcgcgctg
      301 aggaatgaga cctttccagc tggatttgct cttcctctgc ttcttccttt tcagtcaaga
      361 gcttggcctc cagaggagag gatgctgtct ggtgctgggc tacatggcca aggacaagtt
      421 tcggagaatg aatgaaggtc aagtctactc cttcagccag caaccccagg accaagtggt
      481 ggtgtcagga caaccagtga ctctgctgtg tgccatccct gaatatgatg gcttcgtcct
      541 gtggatcaaa gatggcttgg ctctaggtgt aggcagagac ctctcaagct acccccagta
      601 cctggtggtg gggaaccacc tctcaggaga gcatcacctg aagatcctga gggctgagct
      661 gcaggacgat gctgtgtacg agtgccaggc catccaggct gccatccggt cccgccctgc
      721 acgccttaca gtcctggtgc caccagatga ccccatcatc ctaggggggc ctgtgatcag
      781 ccttcgggca ggggatcccc tcaacctcac ctgccatgca gacaatgcca agcctgcagc
      841 ttccatcatc tggctacgca aaggagaggt catcaatggg gccacctact ccaagaccct
      901 gcttcgagat ggcaagcgtg agagcatcgt cagcacactc ttcatctccc caggggacgt
      961 agaaaatggg cagagcattg tgtgccgagc caccaacaaa gccatccccg gaggaaagga
     1021 gacctcagtc accatagaca tccagcatcc accacttgtc aacttgtccg tagaaccaca
     1081 gccggtattg gaggacaata tcgtcacgtt ccactgctct gcaaaggcca acccagctgt
     1141 cacccagtac aggtgggcca aacggggtca catcatcaag gaggcatctg gggagctgta
     1201 taggaccacc gtggactaca catacttctc agagcctgta tcctgcgaag tgaccaatgc
     1261 cttgggcagc accaacctca gccgcacagt ggacgtgtac tttggccctc gaatgacctc
     1321 ggagcctcag tccctgctgg tagatctggg ctcagatgct gtcttcagct gtgcgtggat
     1381 cggcaaccca tctctgacca tcgtgtggat gaaacgaggt tctggtgtgg tcctgagcaa
     1441 tgaaaagacc ctaaccctca aatctgtccg ccaagaggat gccgggaagt acgtgtgccg
     1501 ggctgtggtg ccccgggtag gagctgggga gagagaggtg accttgactg tcaatggacc
     1561 ccccatcatc tccagcacac agacccagca tgccctccat ggagagaagg gccagatcaa
     1621 atgcttcatc cggagcacac caccgcctga ccgaattgcc tggtcctgga aggagaatgt
     1681 gctggagtcg gggacatcag ggcgctacac agtggagacg gtgaacaccg aggagggcgt
     1741 catctccacg ctgaccatta gcaacattgt gcgtgctgac ttccagacca tatacaactg
     1801 tacagcctgg aacagcttcg gctctgacac agagatcatc cgactcaagg aacaagagtc
     1861 agtgccaatg gccgtcatca tcggggtggc cgtaggagct ggcgtggcct tcctcgtcct
     1921 aatggcaacc attgtggcct tctgctgtgc ccgttcccag agaaatctca aaggtgttgt
     1981 gtcagccaaa aatgatattc gagtggagat tgtacacaag gagccagctt ctggtcggga
     2041 ggctgaggac cacaccacca tcaagcagct gatgatggac cggggtgaat tccaacaaga
     2101 ctccgtgctg aagcagctgg aggtcctcaa agaagaggag aaggagtttc agaacctgaa
     2161 ggaccccacc aacggctact acagcgtcaa caccttcaaa gaacaccatt caactccaac
     2221 catctccctg tccagctgcc agccagacct gcgtcccaca ggcaaacagc gagtgcccac
     2281 aggcatgtcc ttcaccaaca tctacagcac cttgagcggc cagggccgcc tctacgacta
     2341 tggacagagg tttgtactgg gcatgggcag ctcttccatt gagctttgtg agcgggagtt
     2401 tcagaggggc tccctcagcg acagcagctc cttcctagac acgcagtgtg acagcagcgt
     2461 cagcagcagc ggcaaacaag atggctacgt gcagtttgac aaggccagca aggcttctgc
     2521 ctcctcttcc caccactccc agtcctcttc ccagaactcc gaccccagtc gacccctgca
     2581 gcggcggatg cagactcacg tctgaggacc gaccaagcac tgtggtgggg atgggccaaa
     2641 gaggaggaca ggccacattc tcgttctcca aggactgggg ctattttgca gaggacccta
     2701 gaactggcca cctccggggt ggcctccaag cacctctgtt aacaccttcc ttcgaagctc
     2761 tgatcaagca caaatctggc tcccgggtgg aaaatgaaga gagtgcggtt gagtgcatag
     2821 tgctcagggc ctttgtctcg tgctcttccc taaaggtccc tcaaacacct tgtcctccca
     2881 tgggcattag tggcagctag aactttgctt ttatgaaact gccgtccact ttgctagctc
     2941 ctcttgctgc ccataagcca tccctgatgc ctgtattcct tacagccttg gggaacggag
     3001 gaccttttcc cagcactgag ctgctccgga gaccccagct tccccactgt gggtagccca
     3061 taccacagag gctggaggct gagaaatgac cccgaccaaa ggagtatttg cctgggagcc
     3121 cgcccccact ttgtttggtg tttgtgtctg tattcttgca gttctgtttt tggacttggt
     3181 gcctctgagc tcggtggtgg gactggccca tccgaatcta gtgtcctcag agccgaggaa
     3241 gggaaggaga gaatgtgaac gcctggagaa cagctgaccc aacacaccct gtgccaggct
     3301 gtgcagttca gagccctcgc ccccaaccct cacaccctgc ttcctgttct cccttccttc
     3361 ccacagcaca atcaagctaa tatgaggagt gtgagaactt ctcctgtcag ggtttgttga
     3421 acagtcactg cagagtgctt cctgggaggt gtgggtttga ggtggggtgg ggctgaaatc
     3481 taggctggag gatgagacag actctttcag ctaatgacca caaagaacaa tgatccattc
     3541 tcctgtagac aggactctgt gtgcaagagg gacagttttc ttcacctctc ccatcactcc
     3601 ccacttaaga ataaacgtta gggccattac ccacaaaaaa
//
