LOCUS       NM_001271398            3364 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus kirre like nephrin family adhesion molecule 2
            (Kirrel2), mRNA.
ACCESSION   NM_001271398 XM_002728739
VERSION     NM_001271398.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3364)
  AUTHORS   Yesildag,B., Bock,T., Herrmanns,K., Wollscheid,B. and Stoffel,M.
  TITLE     Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That
            Regulates Basal Insulin Secretion
  JOURNAL   J Biol Chem 290 (43), 25891-25906 (2015)
   PUBMED   26324709
REFERENCE   2  (bases 1 to 3364)
  AUTHORS   Heikkila,E., Ristola,M., Havana,M., Jones,N., Holthofer,H. and
            Lehtonen,S.
  TITLE     Trans-interaction of nephrin and Neph1/Neph3 induces cell adhesion
            that associates with decreased tyrosine phosphorylation of nephrin
  JOURNAL   Biochem J 435 (3), 619-628 (2011)
   PUBMED   21306299
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Sep 20, 2012 this sequence version replaced XM_002728739.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16418986,
                              SAMN16418988 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-722               JAXUCZ010000001.1  94845398-94846119   c
            723-872             JAXUCZ010000001.1  94845030-94845179   c
            873-1022            JAXUCZ010000001.1  94844013-94844162   c
            1023-1183           JAXUCZ010000001.1  94843701-94843861   c
            1184-1334           JAXUCZ010000001.1  94842960-94843110   c
            1335-1440           JAXUCZ010000001.1  94842684-94842789   c
            1441-1589           JAXUCZ010000001.1  94842460-94842608   c
            1590-1717           JAXUCZ010000001.1  94842087-94842214   c
            1718-1850           JAXUCZ010000001.1  94841863-94841995   c
            1851-1951           JAXUCZ010000001.1  94841357-94841457   c
            1952-2171           JAXUCZ010000001.1  94841004-94841223   c
            2172-2270           JAXUCZ010000001.1  94839692-94839790   c
            2271-2371           JAXUCZ010000001.1  94839166-94839266   c
            2372-2437           JAXUCZ010000001.1  94838651-94838716   c
            2438-3364           JAXUCZ010000001.1  94836243-94837169   c
FEATURES             Location/Qualifiers
     source          1..3364
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..3364
                     /gene="Kirrel2"
                     /note="kirre like nephrin family adhesion molecule 2"
                     /db_xref="GeneID:100359836"
                     /db_xref="RGD:1308456"
     exon            1..722
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     CDS             671..2773
                     /gene="Kirrel2"
                     /note="kin of IRRE-like protein 2; kin of IRRE like 2"
                     /codon_start=1
                     /product="kin of IRRE-like protein 2 precursor"
                     /protein_id="NP_001258327.1"
                     /db_xref="GeneID:100359836"
                     /db_xref="RGD:1308456"
                     /translation="MLASALLVVLCCFRGNAGSSPHFLQQPEDMVVLLGQEARLPCAL
                     GAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQA
                     SQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDARPAPELLWFRD
                     GIRLDGTSFHQITLRDKATGTVENTLFLTPSSQDDGATLICRARSQALPTGRDTAVTL
                     SLQYPPMVTLSAEPQTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVV
                     ADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKPVSVDVGKDASFSCVWRG
                     NPLPRISWTRLGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGVGGGTAQARLTV
                     NAPPVVTALHPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFP
                     APEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRL
                     VAGAASAATSLFMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSAHGPEEETGSSED
                     RGPIVHTDHNDLVLEENEALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPSPMG
                     LPGTPTYYDFKPHLDLVPPCRLYRARAGYLTTPHPRAFTNYMKPTSFGPPDLSSGTPP
                     FPYATLSPPSHQRLQTHV"
     exon            723..872
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1022
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1183
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1334
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1440
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1589
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1717
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1850
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1951
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            1952..2171
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2270
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2371
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            2372..2437
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
     exon            2438..3364
                     /gene="Kirrel2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctctccga cccgcaagcc caaggagcct gggctccgac tccccagggc gcggaagctg
       61 gcgaagcctc agggattccc atttatagct tggtttccac tcagctcagt ccctccagga
      121 ctcgggctga gcaagtttct tccattctct tctctcctcc ccctccctcc tcctcctctt
      181 ctttagcctc ctcctcctcc ccgcctcccc ttcaacctca gcagggtgca ggtgtccaac
      241 tcgagcaagg gccccaactt ggactcagat gttccaactc tcagacaccc tgataatgcg
      301 ggggcgccct cttgctgcgc ggacagctac cctgagcacc cctagccgtc cgcacacaag
      361 gcgccggagt ttctcaatgg gaagaggccg ggtctccagg aggcggggcg aataggatcc
      421 cgcccgccta gtgggtcctt cgcagtccta gggttgcaac cccgtgagcg gtgtagagca
      481 ctggagactg cggacgagcc ggatttcagg gactttgggc cagacataga atcttccagc
      541 ccggagagaa gagtggggtg cagagagggg ttccagtcca gcgtggtgag aggcgagcta
      601 tcgaggaaga agttggaggg caagcagtgc aatcctaagt ctgcgagatc ttggggttca
      661 cacactcagg atgctggcct ccgccctcct cgttgtcctc tgctgtttca gaggaaatgc
      721 aggctcatcg ccccatttcc ttcaacagcc agaggacatg gtggtgctgt tggggcagga
      781 agcccggctg ccctgcgctc tgggcgcata cagggggctc gtgcagtgga ctaaggatgg
      841 gctggctcta gggggcgaaa gagaccttcc agggtggtcc cggtactgga tatcagggaa
      901 ttcagccagt ggccagcatg acctccacat taagcctgtg gagctggaag atgaagcatc
      961 ctatgagtgc caggcctcac aggcaggcct ccgatcacga ccagcccaac tgcatgtgat
     1021 ggtcccccca gaagcacccc aggtactagg cggcccctct gtgtctctgg ttgctggagt
     1081 tcctggaaat ctgacctgtc ggagtcgtgg ggatgcccga cctgcccctg agctactgtg
     1141 gttccgtgat gggatccggc tggatgggac cagcttccac cagatcacgc tgagggacaa
     1201 ggccaccggg acagttgaaa acaccttatt cctgacccct tccagtcagg acgatggagc
     1261 caccttgatc tgcagagcac ggagccaggc cctgcccaca gggagggaca cagcggtgac
     1321 actgagcctt cagtatcccc caatggtgac tctgtctgct gagccccaga ctgcgcagga
     1381 gggagagaag gtaactttcc tgtgtcaagc cactgcccag cctcctgtca ccggctacag
     1441 gtgggcgaag gggggatccc cggtgctcgg ggcacgtggg ccaaggttgg aggtcgttgc
     1501 agatgccacg ttcctgactg agccggtgtc ctgcgaggtc agcaacgcgg tcggaagcgc
     1561 caaccgcagc accgcgctgg aagtgttgta tggacccatt ctgcaggcaa aaccgaagcc
     1621 cgtgtccgtg gacgtgggga aagacgcgtc tttcagctgt gtctggcggg ggaacccact
     1681 tccacggata tcctggaccc gcctcggtgg ctctcaggtg ctgagctccg ggcccacact
     1741 gcggcttccg tccgtggcac tggaggatgc gggcgactat gtgtgcaggg ctgagccgag
     1801 gcgaacgggt gtgggaggcg gcacagcaca ggcaaggctg acagtgaacg caccccctgt
     1861 agtgacagcc ctgcaccctg caccagcctt cctgaggggt cctgctcgcc tccagtgtgt
     1921 ggtgtttgcc tctcctgccc cagactccgt ggtttggtcc tgggacgagg gctttctgga
     1981 ggctggttca ctgggcaggt ttctagtgga ggccttccca gccccagaag tggagggggg
     2041 acagggccca ggccttattt ctgtgctaca catttccgga acccaggagt ccgactttac
     2101 cacaggcttc aactgcagtg cccgcaaccg gctaggtgag ggacgagtcc agatccacct
     2161 gggccgtaga gacttgctgc ctactgtccg gcttgtggct ggagcagctt ctgcagccac
     2221 ctctctcttt atggtcatca ctggagtggt cctctgctgc tggcgccatg gctctctctc
     2281 taagcaaaag aacttggtcc ggatcccagg aagcagtgaa ggttccagtg cacatggccc
     2341 tgaggaggag acaggcagca gtgaggaccg gggtcccatt gtgcacactg accataatga
     2401 tttggttctt gaggaaaacg aggctctgga gacaaaggat ccaaccaatg gttactacaa
     2461 ggttcgaggg gtcagtgtga gccttagcct tggggaagcc cccggaggag gcctcttctt
     2521 gccaccccca tctccgatgg gtcttccagg gactcctact tactatgact tcaagccaca
     2581 tctggattta gtccctccct gcagactgta cagagcacgg gcaggttatc ttaccacccc
     2641 tcatccccga gccttcacca actacatgaa acccacatcc tttggacccc cagatttgag
     2701 ctccggaacg ccccccttcc catatgctac cttgtctccg cccagtcacc agcgtctcca
     2761 gactcacgtg tgaaaacatc tctccaattg aagagcctca ggaccttcag cttaccacat
     2821 agtgtgttgt ccagattttt ggggagtcag agcaagctga tgaccaatcc ctccaaaatg
     2881 gagccctgat ggagggaaag agcactacaa gcatcagaac tgttaatgta tactcagttc
     2941 agccaaagtg gattctccaa gcaggagcaa tatggctgct atacctactt gttctcctgt
     3001 gaggaagaca ttcaagatga tgactaaaca ctatgcagag ggacaaagat ggggactagg
     3061 gctatggttg gaaacatttc tagccagtaa agcagacatg tgaccatctg caccaagagg
     3121 aaggataaca taagacaaat caagatgaaa gaaataaccc ccgcccctcc atcctggcca
     3181 ataaaagtat agccaatatg gctgtccatt ctctgggaac caaaatggcc actatcttga
     3241 ttccttcctt aaagatacag aaagaattga atcccaggaa tgggatgggg tgaaaataaa
     3301 agaaataagg gggattcttg gactaagaat atttatattt aataataaaa aggggggaca
     3361 aaga
//
