LOCUS       NM_001031627            2435 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus kinesin family binding protein (Kifbp), mRNA.
ACCESSION   NM_001031627
VERSION     NM_001031627.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2435)
  AUTHORS   Wilson,R., Geyer,S.H., Reissig,L., Rose,J., Szumska,D., Hardman,E.,
            Prin,F., McGuire,C., Ramirez-Solis,R., White,J., Galli,A.,
            Tudor,C., Tuck,E., Mazzeo,C.I., Smith,J.C., Robertson,E.,
            Adams,D.J., Mohun,T. and Weninger,W.J.
  TITLE     Highly variable penetrance of abnormal phenotypes in embryonic
            lethal knockout mice
  JOURNAL   Wellcome Open Res 1, 1 (2017)
   PUBMED   27996060
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2435)
  AUTHORS   Alves,M.M., Burzynski,G., Delalande,J.M., Osinga,J., van der
            Goot,A., Dolga,A.M., de Graaff,E., Brooks,A.S., Metzger,M.,
            Eisel,U.L., Shepherd,I., Eggen,B.J. and Hofstra,R.M.
  TITLE     KBP interacts with SCG10, linking Goldberg-Shprintzen syndrome to
            microtubule dynamics and neuronal differentiation
  JOURNAL   Hum Mol Genet 19 (18), 3642-3651 (2010)
   PUBMED   20621975
  REMARK    GeneRIF: KBP-depleted PC12 cells were defective in nerve growth
            factor-induced differentiation and neurite outgrowth, suggesting
            that KBP is required for cell differentiation and neurite
            development.
REFERENCE   3  (bases 1 to 2435)
  AUTHORS   Wozniak,M.J., Melzer,M., Dorner,C., Haring,H.U. and Lammers,R.
  TITLE     The novel protein KBP regulates mitochondria localization by
            interaction with a kinesin-like protein
  JOURNAL   BMC Cell Biol 6, 35 (2005)
   PUBMED   16225668
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC098692.1 and BC060521.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098692.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760433 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1420              BC098692.1         1-1420
            1421-2435           BC060521.1         1314-2328
FEATURES             Location/Qualifiers
     source          1..2435
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..2435
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /note="kinesin family binding protein"
                     /db_xref="GeneID:606294"
                     /db_xref="RGD:1593126"
     exon            1..447
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1887
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /note="KIF1 binding protein"
                     /codon_start=1
                     /product="KIF-binding protein"
                     /protein_id="NP_001026797.1"
                     /db_xref="GeneID:606294"
                     /db_xref="RGD:1593126"
                     /translation="MAGAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLE
                     EVRALLGPAPEDDDERAADDGPVDQALGAGEPRDAEGPGAQRALRLAVVEFHLGVNHI
                     DTEELSAGEEHLVRCLSLLRPYRLSLGCVSLFIQAQNNLGILWSEREEIETARTYLES
                     SEALYNQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHME
                     MFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIF
                     GQTGKITATEDTPEVEGDMPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDL
                     DKQSELRALRRKELDEEESVRKRAVQFGTGELRDAISAVEEKVRYLRPLDFEEARELF
                     LLGQHYVYEAKEFFQIDGYVTDHIEVVQDHSALFKVLAFFEADMERRCKMHKRRIAML
                     EPLIVDLNPQYYLLVNRQIQFEIAHAYYDMMDLKVAIADKLREPDSHTVKKINSLNQS
                     ALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLA
                     TSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT"
     exon            448..546
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
     exon            547..626
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
     exon            627..810
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
     exon            811..895
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
     exon            896..1011
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..2422
                     /gene="Kifbp"
                     /gene_synonym="Kbp; Kif1bp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggctagga ggcggccgtc agctcaggcc gcgatggcgg gcgctccggg gccagagatc
       61 cgcgagaagt tccaggctgc gctggctctg tcgcgggtgg agctgcacaa gaacccggag
      121 aaggagccgt acaagtccaa gtacggtgcg cgcgcgctgt tggaggaggt gcgcgcgctg
      181 ctgggcccgg cgccggagga cgacgacgag cgggctgcgg acgatgggcc ggtggaccag
      241 gccttgggcg cgggcgagcc acgggacgcc gagggcccgg gagcgcagcg agccctgcgc
      301 ctcgcggtgg tggagttcca ccttggcgtg aaccacatcg acactgagga actgtctgcc
      361 ggcgaggagc atctggtcag gtgcctgtcg ctgctgcgcc cctaccgcct gtcgctcggc
      421 tgtgtgtctc tcttcatcca ggcgcagaat aacctgggca tcttatggtc tgaaagggaa
      481 gagatcgaaa ctgcccggac ctacctggag tcatcagaag cactgtacaa tcagtacatg
      541 aaagagatcg ggagcccgcc tcttgacccg actgagcact ttcttcctga agaagagaaa
      601 cttactgaac aagagagatc gaaaagattt gagaaggttt atactcataa cctgtactac
      661 ctggctcaag tctatcagca catggaaatg ttcgagaagg ccgctcatta ttgccacagc
      721 acgctaaaac gccagcttga acacaatgcc taccatccca tggagtgggc catcaacgcc
      781 gctaccctgt cacagttcta catcaataag ctctgtttta tggaagccag acattgtctg
      841 tcagctgcta atgttatttt tggtcaaact ggaaaaatca cagccacaga agacactcct
      901 gaagttgaag gagacatgcc ggagctttac catcaaagga aaggggagat agcaagatgc
      961 tggatcaagt actgcttgac tctgatgcag aacgcgcagc tctccatgca ggacaacata
     1021 ggggagctgg atcttgacaa gcagtcggag ctcagggctt tacggaggaa ggagctggat
     1081 gaagaggaga gtgtcaggaa aagggctgta cagtttggaa ctggtgagct gcgcgatgcc
     1141 atctctgcgg tggaggagaa agtgagatac ttgagaccct tagattttga agaagccagg
     1201 gaacttttcc tgctgggtca acactatgtg tatgaggcaa aagagttctt ccagattgat
     1261 gggtatgtta ctgaccatat tgaagttgtc caagaccaca gcgctctgtt caaggtgctc
     1321 gcgttctttg aggctgacat ggagaggcga tgcaagatgc acaagcgcag aatagccatg
     1381 ctagagcccc tgattgtgga cttgaatcca cagtactacc tgttggtcaa caggcagatt
     1441 cagtttgaaa ttgctcacgc ttactatgac atgatggatt tgaaagttgc tattgctgac
     1501 aagctcaggg agcccgactc acacactgtg aaaaagataa atagcttgaa tcagtccgcg
     1561 ctcaagtact accagctctt cctagactcc ctgagagacc caaacaaagt ctttcctgag
     1621 cacatcgggg aggacgttct ccgccctgcc atgctagcta aattccgggt agctcgtctg
     1681 tatggcaaaa tcatcactgc agatcccaag aaagagctag agaatctggc aacatctttg
     1741 gaacattaca aatttattgt tgattactgt gaaactcacc ccgaggctgc ccaggaaata
     1801 gaagttgagc tagaacttag taaagagatg gtcagtcttc tcccaacaaa aatggaaagg
     1861 ttcagagcca agatggccct gacttaagcc ttggtccaga ggaaaggaaa catgcagcct
     1921 gaagccactc ctgtcccccc atagcgaaca aggccagccc cacagtcacc ttcgtgccag
     1981 ggccagaggg aggcactctg agctccagaa gcagtcaggt acccgagtct gtgctaggac
     2041 cttaaccacc ataagttaat aatttatacc taattatgta agtcgccttg ctaacgtgac
     2101 aggtgttttg cattttcaat cgcttgtttt cctgtttaag tacaaacatc tcctgccttg
     2161 atttctacat gttaagtcct tgttaggttc cctacgagga acgacgctgc gtagtgtacc
     2221 tggtagaaga acctgtcact gtggtgaact tgagaaagtc actcctattg tcattctttg
     2281 taagtactta cttccttaaa ctccaaaata aatctttccc ttttgaaaat actaaaaatt
     2341 taagttaata atgtcgcaaa atggcgtatc ttgattacag gactgaagag cttgcacata
     2401 ataaattcac ttgtttcaac taaaaaaaaa aaaaa
//
