LOCUS       NM_001401347            3806 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus kinesin-associated protein 3 (Kifap3), mRNA.
ACCESSION   NM_001401347 XM_008769623
VERSION     NM_001401347.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3806)
  AUTHORS   Phang,H.Q., Hoon,J.L., Lai,S.K., Zeng,Y., Chiam,K.H., Li,H.Y. and
            Koh,C.G.
  TITLE     POPX2 phosphatase regulates the KIF3 kinesin motor complex
  JOURNAL   J Cell Sci 127 (Pt 4), 727-739 (2014)
   PUBMED   24338362
REFERENCE   2  (bases 1 to 3806)
  AUTHORS   Tsai,J.W., Lian,W.N., Kemal,S., Kriegstein,A.R. and Vallee,R.B.
  TITLE     Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear
            migration in neural stem cells
  JOURNAL   Nat Neurosci 13 (12), 1463-1471 (2010)
   PUBMED   21037580
  REMARK    GeneRIF: RNA interference screening of kinesin genes identifies
            Kif1a, a member of the kinesin-3 family, as the motor for basally
            directed nuclear movement in neural stem cells.
REFERENCE   3  (bases 1 to 3806)
  AUTHORS   Insinna,C., Humby,M., Sedmak,T., Wolfrum,U. and Besharse,J.C.
  TITLE     Different roles for KIF17 and kinesin II in photoreceptor
            development and maintenance
  JOURNAL   Dev Dyn 238 (9), 2211-2222 (2009)
   PUBMED   19384852
REFERENCE   4  (bases 1 to 3806)
  AUTHORS   Choi,J., Ha,C.M., Choi,E.J., Jeong,C.S., Park,J.W., Baik,J.H.,
            Park,J.Y., Costa,M.E., Ojeda,S.R. and Lee,B.J.
  TITLE     Kinesin superfamily-associated protein 3 is preferentially
            expressed in glutamatergic neurons and contributes to the
            excitatory control of female puberty
  JOURNAL   Endocrinology 149 (12), 6146-6156 (2008)
   PUBMED   18703627
  REMARK    GeneRIF: Results support the view that decreased KAP3 synthesis
            diminishes GnRH output and delays female sexual development by
            compromising hypothalamic release of glutamate.
REFERENCE   5  (bases 1 to 3806)
  AUTHORS   Haraguchi,K., Hayashi,T., Jimbo,T., Yamamoto,T. and Akiyama,T.
  TITLE     Role of the kinesin-2 family protein, KIF3, during mitosis
  JOURNAL   J Biol Chem 281 (7), 4094-4099 (2006)
   PUBMED   16298999
REFERENCE   6  (bases 1 to 3806)
  AUTHORS   Teng,J., Rai,T., Tanaka,Y., Takei,Y., Nakata,T., Hirasawa,M.,
            Kulkarni,A.B. and Hirokawa,N.
  TITLE     The KIF3 motor transports N-cadherin and organizes the developing
            neuroepithelium
  JOURNAL   Nat Cell Biol 7 (5), 474-482 (2005)
   PUBMED   15834408
  REMARK    Erratum:[Nat Cell Biol. 2005 Jun;7(6):637]
REFERENCE   7  (bases 1 to 3806)
  AUTHORS   Baker,S.A., Freeman,K., Luby-Phelps,K., Pazour,G.J. and
            Besharse,J.C.
  TITLE     IFT20 links kinesin II with a mammalian intraflagellar transport
            complex that is conserved in motile flagella and sensory cilia
  JOURNAL   J Biol Chem 278 (36), 34211-34218 (2003)
   PUBMED   12821668
REFERENCE   8  (bases 1 to 3806)
  AUTHORS   Takakura,A., Miyoshi,J., Ishizaki,H., Tanaka,M., Togawa,A.,
            Nishizawa,Y., Yoshida,H., Nishikawa,Si. and Takai,Y.
  TITLE     Involvement of a small GTP-binding protein (G protein) regulator,
            small G protein GDP dissociation stimulator, in antiapoptotic cell
            survival signaling
  JOURNAL   Mol Biol Cell 11 (5), 1875-1886 (2000)
   PUBMED   10793158
REFERENCE   9  (bases 1 to 3806)
  AUTHORS   Yamazaki,H., Nakata,T., Okada,Y. and Hirokawa,N.
  TITLE     Cloning and characterization of KAP3: a novel kinesin
            superfamily-associated protein of KIF3A/3B
  JOURNAL   Proc Natl Acad Sci U S A 93 (16), 8443-8448 (1996)
   PUBMED   8710890
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Feb 9, 2022 this sequence version replaced XM_008769623.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.249893.1,
                                           SRR26360186.2855678.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               JAXUCZ010000013.1  78671301-78671528
            229-360             JAXUCZ010000013.1  78674441-78674572
            361-515             JAXUCZ010000013.1  78678754-78678908
            516-571             JAXUCZ010000013.1  78680693-78680748
            572-713             JAXUCZ010000013.1  78681953-78682094
            714-813             JAXUCZ010000013.1  78686958-78687057
            814-938             JAXUCZ010000013.1  78688402-78688526
            939-1037            JAXUCZ010000013.1  78690457-78690555
            1038-1216           JAXUCZ010000013.1  78698501-78698679
            1217-1379           JAXUCZ010000013.1  78702793-78702955
            1380-1480           JAXUCZ010000013.1  78726068-78726168
            1481-1589           JAXUCZ010000013.1  78733409-78733517
            1590-1702           JAXUCZ010000013.1  78734812-78734924
            1703-1868           JAXUCZ010000013.1  78741221-78741386
            1869-1994           JAXUCZ010000013.1  78742164-78742289
            1995-2093           JAXUCZ010000013.1  78744673-78744771
            2094-2179           JAXUCZ010000013.1  78747809-78747894
            2180-2369           JAXUCZ010000013.1  78766525-78766714
            2370-2469           JAXUCZ010000013.1  78770656-78770755
            2470-3806           JAXUCZ010000013.1  78796485-78797821
FEATURES             Location/Qualifiers
     source          1..3806
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q22"
     gene            1..3806
                     /gene="Kifap3"
                     /note="kinesin-associated protein 3"
                     /db_xref="GeneID:289168"
                     /db_xref="RGD:1305191"
     exon            1..228
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..2578
                     /gene="Kifap3"
                     /codon_start=1
                     /product="kinesin-associated protein 3"
                     /protein_id="NP_001388276.1"
                     /db_xref="GeneID:289168"
                     /db_xref="RGD:1305191"
                     /translation="MQSEDARYLKRKVKGGNIDVHPSEKALIVQYEVEATILGEMGDP
                     MLGERKECQKIIRLKSLNANTDITSLARKVVEECKLIHPSKLNEVEQLLYYLQNRRDS
                     LSGKEKKEKSSKPKDPPPFEGMEIDEVANINDMDEYIELLYEDLPDKVRGSALILQLA
                     RNPDNLEELLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFSHFHGLITHYK
                     IGALCMNIIDHELKRHELWQEELSKKKKAVDEDLENQTLRKDYDKTFKKYQGLVVKQE
                     QLLRVALYLLLNLAEDTRTELKMRNKNIVHMLVKALDRDNFELLILVVSFLKKLSIFM
                     ENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNKMVQVGLLPKLTA
                     LLGNENYKQIAMCVLYHISMDDRFKSMFAYTDCIPQLMKMLFECSDERIDLELISFCI
                     NLAANKRNVQLICEGNGLKMLMKRALKLKDPLLMKMIRNISQHDGPTKNLFIDYVGDL
                     AAQISSDEEEEFVIECLGTLANLTIPDLDWELVLKEYKLVPFLKDKLKPGAAEDDLVL
                     EVVIMIGTVSMDDSCAALLAKSGIIPALIELLNAQQEDDEFVCQIIYVFYQMVFHQAT
                     RDVIIKETQAPAYLIDLMHDKNNEIRKVCDNTLDIIAEYDEEWAKKIQSEKFRWHNSQ
                     WLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLITSEGALSPDFFN
                     DFHLQNGDVVGQHSFPGSLGMDGFGQPVGILGRPATAYGFRPDEPYYYSFGSR"
     exon            229..360
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            361..515
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            516..571
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            572..713
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            714..813
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            814..938
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1037
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1216
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1379
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1380..1480
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1589
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1702
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1868
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1869..1994
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2093
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..2179
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2369
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2370..2469
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2470..3806
                     /gene="Kifap3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgttttgg ggcccaggag ctgtgggagg ggccggcggc ctcaccgtgg taaccgctgc
       61 gccgccgctg ccccgccttg caggcctcgg gactgtcacc gcctctgctt tgagggtacc
      121 ttggccgggt ccccggaagt agccctccca gatcctcaga ccctcccatt ctccccacgc
      181 cgctgctgcc gccgccatgc aaagcgagga cgccagatac ctcaaaagga aagttaaagg
      241 ggggaatatt gatgtacatc catcagaaaa agctcttatc gttcagtatg aagtggaggc
      301 taccattctt ggagaaatgg gggatcccat gttgggagaa cgaaaggaat gccaaaaaat
      361 catccgcctg aagagtctca atgctaacac agacataacc tctctggccc ggaaagtggt
      421 tgaagaatgt aaactcatcc atccctcaaa gctcaatgag gtggaacagc ttttgtacta
      481 tctacagaac cgccgtgact cattgtcagg aaaagaaaag aaagaaaagt ctagcaagcc
      541 taaagaccca cctccttttg aagggatgga gattgacgag gtggccaaca ttaacgacat
      601 ggatgagtac attgagctct tgtatgaaga ccttccagac aaggtccggg gctcggcctt
      661 gatcctacag cttgctcgaa atcctgataa cctggaagag ctattattaa atgaaactgc
      721 cctgggtgcg ctagcaagag tcctgagaga agactggaaa caaagcgttg agttagctac
      781 aaatatcatt tatatcttct tttgcttctc tagcttttct cattttcatg gactcatcac
      841 tcactataaa attggagcac tgtgtatgaa tatcattgat catgagttaa aaagacacga
      901 gctttggcaa gaagaacttt ctaagaagaa gaaagctgtt gatgaagacc ttgaaaatca
      961 aactttgaga aaggattatg acaaaacctt taaaaaatac cagggacttg tggtaaaaca
     1021 agagcagctc ttgagagttg ctctctattt gcttctgaat cttgcggagg acacgcgtac
     1081 ggaactgaag atgaggaaca agaatatcgt tcacatgttg gtgaaggctc ttgatcggga
     1141 caattttgag ctgctcattc tagtcgtgtc attcttaaag aaactcagta tttttatgga
     1201 gaataaaaat gacatggtag agatggatat tgttgaaaaa ctggtaaaaa tgatcccctg
     1261 tgagcatgaa gatcttctga acatcaccct ccggctcctc ttaaacctct catttgacac
     1321 aggcctgagg aacaagatgg tacaagttgg actcctcccg aagctcactg cactcttggg
     1381 caatgaaaac tacaaacaaa tagcgatgtg tgtgctttac cacataagca tggatgaccg
     1441 cttcaagtcc atgtttgcat atactgactg cataccacag ttaatgaaga tgctctttga
     1501 atgttcagat gaacgaattg acttggagct gatttctttc tgcattaatc ttgctgctaa
     1561 caagagaaat gttcagctca tctgtgaagg aaatgggctg aagatgctca tgaaaagagc
     1621 gctgaagctc aaggaccctc tgctgatgaa gatgatcagg aacatctccc agcatgatgg
     1681 acccactaag aatttgttca ttgattatgt tggggacctt gcagcccaga tttccagtga
     1741 tgaagaggag gagtttgtaa tcgagtgttt gggaacactg gcgaatctga caatcccaga
     1801 tctagactgg gaactggttc tgaaggagta caagctggtt ccattcctca aagacaagct
     1861 aaagccaggt gctgcagaag atgaccttgt tttagaagtg gtcataatga ttggaacagt
     1921 atctatggat gactcttgtg ctgcactgct agctaaatct gggataatcc cagcactcat
     1981 cgaactgctg aatgctcaac aagaagatga tgaatttgtg tgtcagataa tttatgtctt
     2041 ctatcagatg gttttccatc aggccacaag agatgtcata atcaaagaaa cacaagctcc
     2101 agcatatctc atagacctga tgcatgataa aaataatgaa atccggaaag tctgtgataa
     2161 cacgttagat attatcgcag agtatgatga agagtgggca aagaaaattc agagtgagaa
     2221 gtttcgctgg cataactctc agtggttgga gatggtggag agtcgtcaga tggatgagag
     2281 tgagcagtac ttatatggtg atgaccggat tgagccgtac atccatgaag gagacattct
     2341 tgaaaggcct gacctcttct acaactcaga tggactaatc acctctgaag gagctctaag
     2401 tccagacttc ttcaatgact ttcacctcca gaatggagac gtggttggac agcactcatt
     2461 tcctggcagc cttggaatgg atggctttgg tcagccagtg ggaatcctcg gacgccccgc
     2521 caccgcatat ggattccgcc ctgacgagcc ttactactac agctttgggt ctcgataaaa
     2581 tcaccctccc atgtataact cggctgagga gagatctgtg tgctgtgggc taaccttgaa
     2641 tcttgactta ataatgcatg ttgttctcct gtggggctgc gttgcttatt tctccccgct
     2701 gttagcttcg ggttagcgct aacctcacgc ctttcgttga catggttgat gctccaccgt
     2761 tcacgcatcc agccacatct tgaggtgaat gacatttccc atgagactgc tgcagagctg
     2821 ctagcctgga aaagcagatg ctacaccatt tacactacgt gactaatctc tattaaaagg
     2881 tggcatgccc gcaaaggagt gggccaaagt catgtgttca tactgtgttt cacaggaacc
     2941 actcatgtac atgggataca catacttttt ttttttttgc gttctctttc tttttataaa
     3001 ctcctagtgt ttcgtgtgag ccatgctgcc tttacctttt attttaaatg aacctcattc
     3061 tttttatccc atgctgtgtc tggaagtttc tttcacaaag tttttaacta tatgagtttt
     3121 ttaacttaac agtgaacaca tgctataagt aagttatgca cgtatagact agcgagtgac
     3181 ccagagtcct gacatgttaa ctgcagcaga cactgaggag cgggatcctc tgtgagtgca
     3241 gcaggagcaa cactgagctt gtaagttttg ttcttctgag atgtacgatg taaactgtga
     3301 agatgctaag tatttttgcc ttacctaaga aaattaagga aaggactctc tgttcactta
     3361 agttagaagt gggtggtggg aataaaaggg acacaatgat taataatggg ttttgaaaat
     3421 aattcattga ttgtaaaata ctgaaaactt tccttgagaa accaagcaaa tgaatccaat
     3481 atgagcacag atcatctcct actgaaggaa acatacaatt cagaacagtg caggtcaagg
     3541 ggaagatttc tgcttttaaa tttaaaatcc cactgatcca agtatactgt ttaccttaat
     3601 tcacacgttt cacagagtcc tggtgctggg acggtcatct gcctgagaaa tgtaaagcta
     3661 agcaacaggt gtgctctcac ctgacacaca cggtagtgta tgatctggga cggcgtctgt
     3721 gtgtgctcta caactctgaa tgcatgcagc tattgtcttt gtttcccttt acccacaaaa
     3781 tattaaagcc agaaaggttc gaatca
//
