LOCUS       NM_057202               5888 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus kinesin family member 5B (Kif5b), mRNA.
ACCESSION   NM_057202 XM_006254005 XM_341538
VERSION     NM_057202.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5888)
  AUTHORS   Yin,J.B., Liu,H.X., Dong,Q.Q., Wu,H.H., Liang,Z.W., Fu,J.T.,
            Zhao,W.J., Hu,H.Q., Guo,H.W., Zhang,T., Lu,Y.C., Jin,S., Wang,X.L.,
            Cao,B.Z., Wang,Z. and Ding,T.
  TITLE     Correlative increasing expressions of KIF5b and Nav1.7 in DRG
            neurons of rats under neuropathic pain conditions
  JOURNAL   Physiol Behav 263, 114115 (2023)
   PUBMED   36773735
  REMARK    GeneRIF: Correlative increasing expressions of KIF5b and Nav1.7 in
            DRG neurons of rats under neuropathic pain conditions.
REFERENCE   2  (bases 1 to 5888)
  AUTHORS   Shin,E.Y., Lee,C.S., Kim,H.B., Park,J.H., Oh,K., Lee,G.W.,
            Cho,E.Y., Kim,H.K. and Kim,E.G.
  TITLE     Kinesin-1-dependent transport of the betaPIX/GIT complex in
            neuronal cells
  JOURNAL   BMB Rep 54 (7), 380-385 (2021)
   PUBMED   34154701
  REMARK    GeneRIF: Kinesin-1-dependent transport of the betaPIX/GIT complex
            in neuronal cells.
REFERENCE   3  (bases 1 to 5888)
  AUTHORS   Rahmati,M. and Taherabadi,S.J.
  TITLE     The effects of exercise training on Kinesin and GAP-43 expression
            in skeletal muscle fibers of STZ-induced diabetic rats
  JOURNAL   Sci Rep 11 (1), 9535 (2021)
   PUBMED   33953268
  REMARK    GeneRIF: The effects of exercise training on Kinesin and GAP-43
            expression in skeletal muscle fibers of STZ-induced diabetic rats.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5888)
  AUTHORS   Kerendi,H., Rahmati,M., Mirnasuri,R. and Kazemi,A.
  TITLE     High intensity interval training decreases the expressions of KIF5B
            and Dynein in Hippocampus of Wistar male rats
  JOURNAL   Gene 704, 8-14 (2019)
   PUBMED   30978476
  REMARK    GeneRIF: High intensity interval training (HIIT) is associated with
            the down-regulation of gene and protein levels of KIF5B and Dynein
            in the rat hippocampal tissue, although the underlying mechanisms
            have remained unknown. These changes suggest that HIIT may have
            negative effects on both the anterograde and retrograde cytoplasmic
            transports because the cytoplasmic transport is mediated by KIF5B
            and Dynein.
REFERENCE   5  (bases 1 to 5888)
  AUTHORS   Gumy,L.F., Katrukha,E.A., Grigoriev,I., Jaarsma,D., Kapitein,L.C.,
            Akhmanova,A. and Hoogenraad,C.C.
  TITLE     MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus
            KIF5-Dependent Cargo Transport in Sensory Neurons
  JOURNAL   Neuron 94 (2), 347-362 (2017)
   PUBMED   28426968
REFERENCE   6  (bases 1 to 5888)
  AUTHORS   Pigino,G., Morfini,G., Pelsman,A., Mattson,M.P., Brady,S.T. and
            Busciglio,J.
  TITLE     Alzheimer's presenilin 1 mutations impair kinesin-based axonal
            transport
  JOURNAL   J Neurosci 23 (11), 4499-4508 (2003)
   PUBMED   12805290
REFERENCE   7  (bases 1 to 5888)
  AUTHORS   Gould,R., Freund,C., Palmer,F., Knapp,P.E., Huang,J., Morrison,H.
            and Feinstein,D.L.
  TITLE     Messenger RNAs for kinesins and dynein are located in neural
            processes
  JOURNAL   Biol Bull 197 (2), 259-260 (1999)
   PUBMED   10573845
REFERENCE   8  (bases 1 to 5888)
  AUTHORS   Tanaka,Y., Kanai,Y., Okada,Y., Nonaka,S., Takeda,S., Harada,A. and
            Hirokawa,N.
  TITLE     Targeted disruption of mouse conventional kinesin heavy chain,
            kif5B, results in abnormal perinuclear clustering of mitochondria
  JOURNAL   Cell 93 (7), 1147-1158 (1998)
   PUBMED   9657148
REFERENCE   9  (bases 1 to 5888)
  AUTHORS   Vignali,G., Lizier,C., Sprocati,M.T., Sirtori,C., Battaglia,G. and
            Navone,F.
  TITLE     Expression of neuronal kinesin heavy chain is developmentally
            regulated in the central nervous system of the rat
  JOURNAL   J Neurochem 69 (5), 1840-1849 (1997)
   PUBMED   9349526
REFERENCE   10 (bases 1 to 5888)
  AUTHORS   Niclas,J., Navone,F., Hom-Booher,N. and Vale,R.D.
  TITLE     Cloning and localization of a conventional kinesin motor expressed
            exclusively in neurons
  JOURNAL   Neuron 12 (5), 1059-1072 (1994)
   PUBMED   7514426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On or before Sep 28, 2022 this sequence version replaced
            XM_006254005.2, NM_057202.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.36780.1,
                                           SRR26643288.57731.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-529               JAXUCZ010000017.1  56185386-56185914
            530-617             JAXUCZ010000017.1  56192147-56192234
            618-691             JAXUCZ010000017.1  56196051-56196124
            692-796             JAXUCZ010000017.1  56196798-56196902
            797-845             JAXUCZ010000017.1  56197535-56197583
            846-901             JAXUCZ010000017.1  56198213-56198268
            902-989             JAXUCZ010000017.1  56198352-56198439
            990-1114            JAXUCZ010000017.1  56198591-56198715
            1115-1219           JAXUCZ010000017.1  56199924-56200028
            1220-1365           JAXUCZ010000017.1  56200311-56200456
            1366-1514           JAXUCZ010000017.1  56201282-56201430
            1515-1708           JAXUCZ010000017.1  56202560-56202753
            1709-1777           JAXUCZ010000017.1  56203276-56203344
            1778-1984           JAXUCZ010000017.1  56206163-56206369
            1985-2128           JAXUCZ010000017.1  56206744-56206887
            2129-2317           JAXUCZ010000017.1  56209384-56209572
            2318-2435           JAXUCZ010000017.1  56209998-56210115
            2436-2497           JAXUCZ010000017.1  56211062-56211123
            2498-2607           JAXUCZ010000017.1  56211216-56211325
            2608-2709           JAXUCZ010000017.1  56211868-56211969
            2710-2770           JAXUCZ010000017.1  56213172-56213232
            2771-2842           JAXUCZ010000017.1  56213329-56213400
            2843-2947           JAXUCZ010000017.1  56213577-56213681
            2948-3164           JAXUCZ010000017.1  56214896-56215112
            3165-3314           JAXUCZ010000017.1  56215891-56216040
            3315-5888           JAXUCZ010000017.1  56220417-56222990
FEATURES             Location/Qualifiers
     source          1..5888
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.1"
     gene            1..5888
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /note="kinesin family member 5B"
                     /db_xref="GeneID:117550"
                     /db_xref="RGD:621559"
     exon            1..529
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     CDS             404..3295
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /note="UKHC; ubiquitous kinesin heavy chain; conventional
                     kinesin heavy chain"
                     /codon_start=1
                     /product="kinesin-1 heavy chain"
                     /protein_id="NP_476550.1"
                     /db_xref="GeneID:117550"
                     /db_xref="RGD:621559"
                     /translation="MADPAECNIKVMCRFRPLNESEVNRGDKYVAKFQGEDTVMIASK
                     PYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP
                     EGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKN
                     RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQ
                     TEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVP
                     YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE
                     LTAEQWKKKYEKEKEKNKTLRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTA
                     DKDVAITNDKPAAAIGMAGSFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
                     TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQE
                     VEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIG
                     IAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEE
                     NEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDSLGEELVQLRAQEKVHE
                     MEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKEKLITDLQDQNQKM
                     VLEQERLRVEHERLKAVDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHN
                     LRKLFVQDLATRVKKSAEVDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADL
                     RCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARR
                     GHSAQIAKPIRPGQHPAASPTHPGAVRGGGSFVQNNQPVGLRGGGGKQA"
     exon            530..617
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            618..691
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            692..796
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            797..845
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            846..901
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            902..989
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1114
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1219
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1365
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..1514
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1708
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1777
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1778..1984
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2128
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2317
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2318..2435
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2436..2497
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2498..2607
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2608..2709
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2710..2770
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2771..2842
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2843..2947
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            2948..3164
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            3165..3314
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
     exon            3315..5888
                     /gene="Kif5b"
                     /gene_synonym="Khc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcctgggca ctaaggcctt tgagggtgtg agtgtcagct ggcccggagg ccggcgagct
       61 gccgggacag gatagtgggc cgagccatag gccccggctg tccctcccgg aaagaaaaga
      121 aggagccgct cgccagtccc ggcagcctgc agagatcggt gagggagacg ctgaggagca
      181 ctgaggcgct gtgggcgctg ccgccatgac cgccatgatg gagcggaagt gaactaaggg
      241 cgcgggctgc cggtgatagc gctttggtct agctgcctgg ggctcgcagc gctgcggagc
      301 ccgggccttc gggtcctcgc gacccctgct tcttggctcc cgtcgcttat cccactgagc
      361 ggcggggagt ggctcccggc ctgcagtccc ggctgccaga aagatggcgg acccggcgga
      421 gtgcaacatc aaagtgatgt gtcgcttcag acctctcaac gagtctgaag tgaaccgcgg
      481 cgacaagtat gtcgccaagt tccagggaga agacacggtg atgattgcgt ccaagcctta
      541 tgcatttgat cgtgtgttcc agtcaagcac atctcaagag caagtataca acgattgtgc
      601 aaagaagatt gttaaagatg ttcttgaggg ctataatgga acaatatttg catatggaca
      661 aacatcatct ggaaagaccc acacaatgga gggtaaactt catgatccag aaggcatggg
      721 gattattcca agaatagtgc aagatatttt taattatatt tactccatgg atgaaaattt
      781 ggaatttcat attaaggttt catattttga aatatatttg gataagataa gggacctgtt
      841 agatgtttca aagactaacc tttcagtcca tgaagacaaa aaccgtgttc cctatgtaaa
      901 ggggtgcaca gagcgttttg tgtgtagtcc agatgaagtt atggatacca tagatgaagg
      961 gaaatccaac agacacgtag cagttacaaa tatgaatgaa catagctcta ggagtcacag
     1021 tatatttctt atcaatgtaa agcaagagaa tacacagaca gaacagaaac tcagtgggaa
     1081 gctttatctg gttgatttag ctggaagtga aaaggttagt aaaactggag ctgagggtgc
     1141 cgtgctggat gaagctaaga acatcaacaa gtcactttct gcacttggaa atgtcatttc
     1201 tgctttggca gaaggcagta cctatgttcc ttatcgagac agtaaaatga ccagaattct
     1261 tcaagattca ttaggtggca actgtaggac cactattgtc atttgctgct ctccgtcatc
     1321 ttacaatgag tctgagacaa agtcaacact cctctttggt caaagggcca aaacaataaa
     1381 gaacacagtc tgtgtcaacg tagagttaac tgcagagcag tggaaaaaga agtatgaaaa
     1441 agaaaaggaa aaaaataaga ctctacggaa caccattcag tggctggaaa acgagctcaa
     1501 ccgatggcgt aacggggaaa cagtgcctat tgatgagcag tttgacaaag agaaggctaa
     1561 tttggaagcc ttcacagcag ataaagatgt tgctattacc aatgacaaac cggctgctgc
     1621 aatcggaatg gctggtagtt ttacagatgc tgagagaaga aagtgtgaag aagaaattgc
     1681 taaattgtat aaacaacttg atgacaagga tgaagagatt aaccaacaga gccaactggt
     1741 ggagaaattg aagacacaaa tgttggatca ggaagagctt ctggcatcaa ccagaaggga
     1801 tcaagataat atgcaagctg aactgaatcg cctccaagca gaaaatgatg cttctaaaga
     1861 agaagtcaaa gaagttttac aggccttaga ggagctggct gttaattatg atcagaagtc
     1921 tcaggaagtt gaagacaaaa caaaggaata tgaattgctt agtgatgaat tgaatcaaaa
     1981 atctgcaact ttagcaagta ttgatgctga gcttcagaag ctgaaggaaa tgaccaacca
     2041 ccagaagaaa cgagcagctg aaatgatggc atcattacta aaagaccttg cagaaatagg
     2101 aattgctgtg ggaaataatg atgtaaagca accggagggg actggtatga tagatgaaga
     2161 gtttactgtt gcaaggctct acattagcaa aatgaaatca gaagtaaaaa ccatggtgaa
     2221 acgctgcaaa cagctagaaa gcacacagac tgagagcaac aaaaaaatgg aagaaaatga
     2281 gaaggagtta gcagcatgcc agcttcgtat ctcccaacat gaagccaaaa tcaagtcact
     2341 gactgaatac cttcaaaatg tagaacaaaa gaagagacag ctggaggaat ctgtggactc
     2401 ccttggtgag gagctagtcc aacttcgagc acaagagaaa gtccatgaaa tggaaaaaga
     2461 gcacttgaac aaggttcaga ctgcaaatga agtcaagcaa gctgttgaac agcagatcca
     2521 gagtcacaga gaaacccacc aaaaacaaat cagtagttta cgagatgaag ttgaggcaaa
     2581 ggaaaagcta atcactgatc tccaagacca aaaccagaag atggtgttgg aacaggagcg
     2641 gctaagggtg gagcatgaga ggctaaaggc tgtagaccag gagaagagca ggaagctgca
     2701 tgagctcacg gttatgcaag acagacgaga acaagcaagg caagatttga aggggttgga
     2761 agagacggtg gcaaaagaac ttcagacttt acacaacctg cgcaagctct ttgttcagga
     2821 cttggctacc agggtgaaaa agagcgctga ggtggactca gacgacactg gcggcagtgc
     2881 tgcacagaag cagaaaatct ccttccttga aaacaatctg gagcagctca ccaaagtgca
     2941 caagcagttg gtgcgtgata atgcagatct tcgctgtgaa cttcctaagt tagagaaacg
     3001 acttagagct actgcagaga gagtgaaagc tttggagtca gccctgaaag aagccaaaga
     3061 aaatgcatct cgagaccgca aacgctatca gcaagaagta gacaggataa aggaagcagt
     3121 caggtcaaag aatatggcca gaaggggaca ctctgcacag attgcaaaac ctatccgtcc
     3181 tggacagcat ccagcagcct ctccaactca ccccggtgca gttcgtggag gaggctcatt
     3241 tgttcagaac aaccagccag tggggcttcg aggtggtgga ggcaagcagg cgtgaacacc
     3301 gacacacatt gcaggtgttg aaaagtaatt gaagtttgaa gaggacgtaa aatcagtctt
     3361 tcaataacta acctctatcc cttgggattg taggaattta attttctaat gtgtaaatta
     3421 ctcctggctt gtacagctgt ttcctaccca ctcttgtaag ctctgctgct tcccaacact
     3481 agagtgcaat gctgatgtcc tagaagggag atgacagttt acaactgtgg ccctacttac
     3541 tacatagtct gtccatcatg tcttcactgt gccgagtaac tgtgttacag gactgtgcta
     3601 cttgattggc cttttctgtg tatgtgtaat cttggtttac attacctagc tgctattgct
     3661 tttcatgttc ccttttctac taaaatgtct tttttttttt tttatggaaa tacggaacat
     3721 ttagattaaa tgtcttaaat tttaccactt ataacactac ttgccacaga atatatcagg
     3781 tcagtactgt attttaaaag tccctcaagt gggatacaca actttaatcc caagcagagg
     3841 cagatgggta tcagtcagac agttcagttc agcctggcct acatagtgag ttccaggaca
     3901 gccagggcta tatagggtga ccctgtctca aaactcaaga aataaaaagt tcacttaaaa
     3961 ataaaaatcc ttgaaatgaa attagggttc atgttgctgg tatagtctct gaagcttgcc
     4021 tctgaaaaca ttgagcttcg agacctctga cttaattagc caggagttca agaccgagca
     4081 ggctcatgag atgtctgttg catattactt tgaatacaaa tatcttacat atcaaaagtg
     4141 aatattatgt taaagatgag tttggaaatg actatatccc ttctttccac ttctgcactt
     4201 aacatagctt aacataggga cagtggtgcc ctgctttatt ctgttatatc cacctgctaa
     4261 agtaagaatt gaacagaagc taatgtcatc ctcaatatta ggaaataagt ggattaagac
     4321 attatagaat taaataattt tcaaatgtta aataattgtg ttgactgata aatttatagc
     4381 ctttgaaaaa tgagaaaaat tgtgaacagg acagataaac tataaattta aaactacatg
     4441 gttaattttg ctctgaaatc ttgaaggtgg tttttacttt ttacactaag tcatacacta
     4501 taatttgttt agttaggaat agtaaattgt ttggaagtca ctaataattc tcaaaaaaaa
     4561 tgagaaaaaa ttgttggcca taatgaataa tttttaaatt agaactaagt gtatacctat
     4621 ttttggcact tatttttcag atgattaaac tcaatcaagt atattttaag gatctataaa
     4681 agtaacaggg aaagattttc aacctctgct tcctcagtgc ttagggtaac tgcagccctg
     4741 ttagcaagaa atccacagga aatggagtgt ctgaggttat ttgataagta gagaagcttt
     4801 ggaagttctg tgttagaatc tggctggcag aatctttgga aaagttttat atacagatat
     4861 ttgtattatt aaatttggag ccatagtcag aagactcaga tcataattgg cttatttttc
     4921 tatttcctta actattgtaa tttccacttt tataataatt ttgatttgaa aaataaattt
     4981 atttattttt ttaacagtca gaatctttgc tgttgtagtc tgcagccttt aatgattgtg
     5041 ttgcttttat gattgaaaga aacactccac aaattgaaga gagagcttga tgcagcgagg
     5101 tgtaagcggt tagtaaggtg catcgttcgt gatgcacggc tcctgtgctc atcgctgtct
     5161 gagaggcgtc tggctgcatc cataaggaca gtcttcccaa aggaaaactt gcctcttggg
     5221 cagttttcac agtgggaaag aaatcctctc ttgtctgagt atagaagttt taagatgtat
     5281 catgggtgtt ggtgcttgta taacacacaa tgaattgtaa ctagcatgtt aagaaaacac
     5341 attgttagtt ttttttttaa tcttaaatgt ttcttttcta tttataattt caaactttca
     5401 taaagtatac taagaatttc ataaatttct tttcagtgaa ctgaactgct cttttttgct
     5461 atgataggtc atttaaaata gcattcactc aaaatggaca tttttaatca tctagaatat
     5521 tgaaatattt taatttgcag tgtctttttt ttgtgactgg atatattaat gttcctctga
     5581 gtggtattag taattggttc agaagagaaa ctcaatgaaa tacgaatagt atttattcat
     5641 ggtgatcaat taaattattt gcctaattta aggaaactag ctactatgca ttactgaatt
     5701 tatttgcaac tctgaattga tttgaggtaa cagaagagag tctaagccta cctgtggaat
     5761 atgttggttt attttcagtg tttaggatta catttaaaca taattggttt gggaaaacaa
     5821 catataattt taagttaacc tgcatgctgt aaatgtattt aaataaagga aaatcttttt
     5881 gaaatgta
//
