LOCUS       NM_001400930            4617 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus kinesin family member 4A (Kif4a), mRNA.
ACCESSION   NM_001400930 XM_006257113
VERSION     NM_001400930.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Heintz,T.G., Heller,J.P., Zhao,R., Caceres,A., Eva,R. and
            Fawcett,J.W.
  TITLE     Kinesin KIF4A transports integrin beta1 in developing axons of
            cortical neurons
  JOURNAL   Mol Cell Neurosci 63, 60-71 (2014)
   PUBMED   25260485
  REMARK    GeneRIF: Knockdown of KIF4A expression with shRNA reduced the level
            of integrin beta1 in axons of developing neurons.
REFERENCE   2  (bases 1 to 4617)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 4617)
  AUTHORS   Bisbal,M., Wojnacki,J., Peretti,D., Ropolo,A., Sesma,J., Jausoro,I.
            and Caceres,A.
  TITLE     KIF4 mediates anterograde translocation and positioning of
            ribosomal constituents to axons
  JOURNAL   J Biol Chem 284 (14), 9489-9497 (2009)
   PUBMED   19158085
  REMARK    GeneRIF: KIF4 is involved in the anterograde trafficking of
            ribosomal constituents to axons
REFERENCE   4  (bases 1 to 4617)
  AUTHORS   Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E.,
            Fan,J.B., Abraham,R.T. and Jiang,W.
  TITLE     Functional analysis of human microtubule-based motor proteins, the
            kinesins and dyneins, in mitosis/cytokinesis using RNA interference
  JOURNAL   Mol Biol Cell 16 (7), 3187-3199 (2005)
   PUBMED   15843429
REFERENCE   5  (bases 1 to 4617)
  AUTHORS   Skop,A.R., Liu,H., Yates,J. 3rd, Meyer,B.J. and Heald,R.
  TITLE     Dissection of the mammalian midbody proteome reveals conserved
            cytokinesis mechanisms
  JOURNAL   Science 305 (5680), 61-66 (2004)
   PUBMED   15166316
REFERENCE   6  (bases 1 to 4617)
  AUTHORS   Sekine,Y., Okada,Y., Noda,Y., Kondo,S., Aizawa,H., Takemura,R. and
            Hirokawa,N.
  TITLE     A novel microtubule-based motor protein (KIF4) for organelle
            transports, whose expression is regulated developmentally
  JOURNAL   J Cell Biol 127 (1), 187-201 (1994)
   PUBMED   7929562
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Jan 28, 2022 this sequence version replaced XM_006257113.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.32165.1,
                                           SRR26643292.65549.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                JAXUCZ010000021.1  69761883-69761952
            71-380              JAXUCZ010000021.1  69762072-69762381
            381-495             JAXUCZ010000021.1  69762499-69762613
            496-686             JAXUCZ010000021.1  69771815-69772005
            687-779             JAXUCZ010000021.1  69774031-69774123
            780-946             JAXUCZ010000021.1  69776714-69776880
            947-1041            JAXUCZ010000021.1  69777102-69777196
            1042-1158           JAXUCZ010000021.1  69799140-69799256
            1159-1334           JAXUCZ010000021.1  69800091-69800266
            1335-1396           JAXUCZ010000021.1  69804341-69804402
            1397-1529           JAXUCZ010000021.1  69812297-69812429
            1530-1588           JAXUCZ010000021.1  69814926-69814984
            1589-1694           JAXUCZ010000021.1  69815090-69815195
            1695-1751           JAXUCZ010000021.1  69820583-69820639
            1752-1937           JAXUCZ010000021.1  69822014-69822199
            1938-2041           JAXUCZ010000021.1  69822745-69822848
            2042-2186           JAXUCZ010000021.1  69823947-69824091
            2187-2297           JAXUCZ010000021.1  69825630-69825740
            2298-2381           JAXUCZ010000021.1  69834823-69834906
            2382-2495           JAXUCZ010000021.1  69835574-69835687
            2496-2651           JAXUCZ010000021.1  69842844-69842999
            2652-2752           JAXUCZ010000021.1  69843114-69843214
            2753-2882           JAXUCZ010000021.1  69844908-69845037
            2883-3053           JAXUCZ010000021.1  69846508-69846678
            3054-3161           JAXUCZ010000021.1  69847181-69847288
            3162-3239           JAXUCZ010000021.1  69848376-69848453
            3240-3338           JAXUCZ010000021.1  69848966-69849064
            3339-3515           JAXUCZ010000021.1  69849548-69849724
            3516-3632           JAXUCZ010000021.1  69861412-69861528
            3633-3755           JAXUCZ010000021.1  69863159-69863281
            3756-4617           JAXUCZ010000021.1  69863474-69864335
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq22"
     gene            1..4617
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /note="kinesin family member 4A"
                     /db_xref="GeneID:84393"
                     /db_xref="RGD:620526"
     exon            1..70
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            71..380
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..3956
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /note="kinesin heavy chain member 4; kinesin family member
                     4"
                     /codon_start=1
                     /product="chromosome-associated kinesin KIF4A"
                     /protein_id="NP_001387859.1"
                     /db_xref="GeneID:84393"
                     /db_xref="RGD:620526"
                     /translation="MKEEVKGIPVRVALRCRPLVSKEINEGCQTCLSFVPGEPQVVVG
                     TDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAY
                     TAEQEHDSAIGVIPRVIQLLFKEINKKTDFEFTLKVSYLEIYNEEILDLLCSSREKAS
                     QINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFT
                     ISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVIS
                     ALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRA
                     RKIKNKPIINIDPQAAELNHLKQQVQQLQVLLLQAHGGTLPGNINVKPSENLQSLMEK
                     NQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQK
                     LAETLEDQEVKENIEIICNLQQAIARLSDEAVACMTATIDTAGEVDTQEQSSPDTSRS
                     SDVFSTQHALRQAQMSKELIELNKELALKEALAKKMTQNDNQLQPIQFQYQDNIKNLE
                     LEVLSLQKEKEELVLELQTAKKDVNQAKLSERRRKRLQELEGQIAELKKKLHEQSKLL
                     KLKETTELTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRK
                     RQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQSRGMEGT
                     AARMKSWLGNEIEVMVSTEEAKRHLNDLLEERKILAQDVAQLKEKRESGENPPPKLRR
                     RTFSRDEVHGQDSGAEDSISKQIESLESELELRSAQIADLQQKLLDAESEDQPKQRWE
                     NIATILEAKCAIKYLVGELVSSKIQVSKLESGLSQSKASCIEVQKMLFEEQNHFAKIE
                     TELKEELVRVEQQHQEKVLYLLSQLQQCQVTEKQLEESVSEKEQQLLSTLKCQEEELR
                     KMQEVCEQNQQLLQENSAIKQKLNLLQVVSKEKPHLVRNILQSPDSSFEYIPPKPKPF
                     RIKEKCPEKSFAIEDLQYYSETSVAEEENEDSDDHADEEWIPTKLVKVSKKNIQGCSC
                     KGWCGNKQCGCRKQKSDCNGACSCDPTKCRNRHHSQDNSDVIELNQDSENSFKLEDPT
                     EVTSGLSFFNPVCTTPSSKILKEMCDADQVLLRQPDFASSSDHLELKPIASETQENKA
                     MGKKKKRALASNTSFFSGCSPIQEESH"
     exon            381..495
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            496..686
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            687..779
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            780..946
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1041
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1158
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1334
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1396
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1529
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1588
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1694
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1695..1751
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1937
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2041
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2186
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2187..2297
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2381
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2382..2495
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2496..2651
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2652..2752
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2753..2882
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            2883..3053
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3054..3161
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3162..3239
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3240..3338
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3515
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3516..3632
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3633..3755
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..4617
                     /gene="Kif4a"
                     /gene_synonym="Kif4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaacttggc ggttaaagct ccggttggaa cagggcgcca gggaagatcg gggaagggac
       61 gtttagtttg tattgggact gacaaaccat taggcggtgg ccaagagtga caggacacag
      121 tgatcctgct gggagggaga gtgcatcagc gagttccgag tctcctacgg cctgagaagg
      181 gcctttctac tcctgccaac ctcggaaggt tcctgggaga gctggcttca cttggccagg
      241 acacctgctg agctggtacc atgaaagaag aggtgaaggg aattcctgta agagtggcac
      301 tgcgttgtcg cccccttgtc tctaaagaga ttaatgaggg ctgccagacg tgcctttctt
      361 ttgtgcccgg agagcctcag gtggtggttg gtactgataa atcatttacc tacgattttg
      421 tgtttgaccc ctctactgaa caggaagagg tctttaatac agcagtagct ccactcataa
      481 aaggcgtgtt taaaggatac aatgcaactg tcctggccta tgggcagact ggatctggga
      541 agacttattc aatgggaggt gcatacactg cagaacaaga acatgactca gccattgggg
      601 ttattcccag ggtaatacaa ctgctcttca aagaaattaa taaaaagact gactttgaat
      661 ttactctgaa agtgtcttac ttggagattt ataatgaaga aattttggac cttctatgtt
      721 catctcgtga gaaagcatct caaataaata tccgggagga tcctaaggaa ggcataaaga
      781 ttgtgggact gacggagaag actgtgctag ttgcctcgga cactgtttcc tgtctagagc
      841 agggtaacaa ctgcaggact gtggcctcca cagctatgaa ctcccagtca tctcggtctc
      901 atgccatctt tacaatctcc atcgagcaaa ggaagaaaaa tgacaaaaat agcagtttcc
      961 gttccaagct gcatcttgta gaccttgctg gatcagaaag acagaagaaa accaaggccg
     1021 agggagatcg tctgaaagag ggtattaata tcaatcgagg ccttctgtgc ttgggaaatg
     1081 taattagtgc tcttggagat gacaaaaagg gtaactttgt gccctacaga gattccaagc
     1141 tgactcgact gcttcaagat tctctaggag gcaatagcca tactcttatg atcgcctgtg
     1201 tgagtcctgc tgattccaac ctagaggaaa cattaaatac ccttcgctat gctgacagag
     1261 caagaaaaat caagaacaaa cctattatta atattgatcc ccaggcagct gaactaaatc
     1321 accttaaaca acaggtccaa cagctgcagg tcttgttgct acaagcccat ggaggcacct
     1381 tgcctgggaa tataaatgtg aaaccatcag aaaacctcca gtccctgatg gagaagaatc
     1441 agtctctggt ggaagagaat gaaaaattaa gtcgtggtct gagtgaggca gctggtcaga
     1501 cagcccagat gttggagagg atcattttga ctgagcaagc aaatgagaaa atgaatgcca
     1561 agctagaaga actcagacag catgcagcct gcaaagtgga tcttcaaaag ctagcagaaa
     1621 cattggaaga ccaggaagta aaagaaaaca tagagatcat ttgcaaccta caacaagcga
     1681 ttgcccggtt gtctgatgaa gcggttgctt gcatgactgc aaccatcgat actgcagggg
     1741 aagtagacac tcaagagcaa agcagtccag ataccagcag gtcttctgat gttttcagca
     1801 ctcaacatgc tctccgtcaa gctcagatgt ccaaggagct gattgagttg aataaagaac
     1861 ttgcattgaa agaagcccta gctaagaaga tgacccagaa tgacaaccag ctacagccca
     1921 ttcagttcca gtaccaggat aatattaaaa atctagaatt ggaagtcctc agtctacaga
     1981 aggaaaaaga agaattggtt cttgaacttc aaacagcaaa gaaggatgtc aaccaagcca
     2041 agttgagcga acgccgtcgc aaacgtcttc aggagctgga gggtcaaata gctgagttga
     2101 aaaagaaact tcatgaacag tccaaacttc tgaagctgaa ggaaaccact gagcttactg
     2161 tctccaagct gaaccaggag atacggatga tgaaaaacca gcgagtccag ttaatgcgtc
     2221 aaatgaaaga ggatgctgag aagtttaggc agtggaagca acaaaaagac aaagaagtaa
     2281 tccagctaaa agaacgggat cgtaaaaggc aatacgaact gctcaaactt gaaagaaact
     2341 tccagaaaca gtctaatgtg ctcagacgta aaactgagga ggcagcagct gctaacaaac
     2401 gtcttaagga tgctctccaa aagcaaaagg aggttgcaga aaaacggaaa gagacccaga
     2461 gccgtggaat ggaaggcact gcagctcgaa tgaagagttg gcttggaaat gaaatcgagg
     2521 ttatggtcag taccgaggaa gccaaaaggc atctgaatga ccttcttgaa gagagaaaga
     2581 tccttgctca ggatgtggca caactcaaag aaaaaagaga atctggagag aatccacctc
     2641 ctaaactccg aaggcgcaca ttctcacgag atgaagtgca tggtcaagat tcaggagcag
     2701 aggattctat ttcaaagcag attgaaagcc tggagagtga attggagctc aggagtgctc
     2761 agattgcaga cctacagcaa aagcttctgg atgctgaaag tgaagaccag ccaaaacaac
     2821 gctgggagaa tattgccacg attctcgaag ccaaatgtgc cataaagtat ttagttggag
     2881 agctggtctc ctccaaaata caggtgagca aactggaaag cggcctgagt cagagcaagg
     2941 ccagctgtat tgaagtgcag aagatgctgt ttgaggaaca aaatcatttt gctaaaatag
     3001 agaccgagtt gaaagaagag ctggtcagag tggagcagca gcaccaggaa aaggtgttgt
     3061 accttctcag tcagctgcag caatgccaag tgacagagaa acagctggag gagtcggtta
     3121 gtgagaagga acagcagctg ctgagcaccc tgaaatgtca ggaggaagag cttaggaaga
     3181 tgcaagaagt gtgtgagcaa aatcagcagc ttctgcaaga aaacagtgcc atcaagcaga
     3241 aactgaacct cctccaagta gtcagcaaag agaaacccca tcttgtgaga aatatcctcc
     3301 agtctccgga ctcttccttt gaatatattc cacctaagcc caaacctttc cgtattaaag
     3361 aaaaatgccc agagaaaagc ttcgccatcg aggacctgca gtattattca gagacttctg
     3421 tggctgagga ggagaatgag gacagtgatg accatgctga tgaggagtgg atcccaacaa
     3481 aattagtcaa ggtgtccaag aagaacatcc aagggtgttc ctgcaaaggc tggtgtggga
     3541 acaagcaatg tggatgcaga aagcaaaagt cagactgtaa tggggcctgc agctgtgacc
     3601 ccacaaaatg ccgcaaccgc catcacagcc aggacaactc agatgttatt gagctaaacc
     3661 aagattctga aaactccttc aaactggaag atcccacaga ggtgacctca ggattaagct
     3721 tcttcaaccc tgtttgtacg actcccagta gcaagatcct aaaagaaatg tgtgatgcag
     3781 atcaggtgct gctgaggcag cctgattttg cctcttcctc tgaccatcta gaactgaaac
     3841 ctattgcatc agaaacacaa gaaaataagg ccatggggaa gaagaagaag cgagctctag
     3901 ccagcaatac cagcttcttc tctggctgct cccctattca agaagagtcc cactgaggtt
     3961 agggccactg tctcttctgt ctgccctgga cacactctga ggctgcagca cagaggggaa
     4021 gggcactaat gacttctgta gcttttaggt cctgctattg agaaaaggag aataagtccc
     4081 tgaaaggaag agggcctcta ctgtctaagc tctctgccta caaaaactac tttgcttctt
     4141 tagaaggtgc tgaaccttct actggagaga gaaccaactg accttcctga tactcaagag
     4201 gaaccagtcc ccaggacagt ctagctcgct ctctgtgagc agttgagttg tatcttcatg
     4261 gagtcgaggt caacatgttc ttctcttatg atcacatcag cttaatggac gagtgggatg
     4321 gtgacctggc tcgactccgt caccacacct caggaattgg gcagggagct tccctgctcc
     4381 attccaactc cggactttac aaacccttca actgtccgtc acccatgtta ctgaagtgaa
     4441 tgaaacattt taaaaatgtt aaaataaata aaccttagct catctactat ttgaaggaga
     4501 tccttctatg ctagaggaag aagtaaaatt ccaacatgtt ttcttcagcc cctgggaagt
     4561 cttaaagcat ccatttcagt ttccccacaa atacacatac ctcctttttc tgggaaa
//
