LOCUS       NM_001106529            5604 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus kinesin family member 3B (Kif3b), mRNA.
ACCESSION   NM_001106529 XM_001061322 XM_001061386 XM_001061444 XM_001061504
            XM_215883
VERSION     NM_001106529.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5604)
  AUTHORS   Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A,
            Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P,
            Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O'
            Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E,
            Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M,
            Doxsey S, Jackson A, Stupka E, Winey M and Beales PL.
  TITLE     The kinetochore protein, CENPF, is mutated in human ciliopathy and
            microcephaly phenotypes
  JOURNAL   J Med Genet 52 (3), 147-156 (2015)
   PUBMED   25564561
  REMARK    Erratum:[J Med Genet. 2016 Oct 13;:. PMID: 27738186]
REFERENCE   2  (bases 1 to 5604)
  AUTHORS   Broekhuis JR, Verhey KJ and Jansen G.
  TITLE     Regulation of cilium length and intraflagellar transport by the
            RCK-kinases ICK and MOK in renal epithelial cells
  JOURNAL   PLoS One 9 (9), e108470 (2014)
   PUBMED   25243405
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5604)
  AUTHORS   Yu X, Wen H, Cao J, Sun B, Ding T, Li M, Wu H, Long L, Cheng X, Xu
            G and Zhang F.
  TITLE     Temporal and spatial expression of KIF3B after acute spinal cord
            injury in adult rats
  JOURNAL   J Mol Neurosci 49 (2), 387-394 (2013)
   PUBMED   23093447
  REMARK    GeneRIF: KIF3B gene expression in neurons and microglia is
            upregulated after spinal cord injury.
REFERENCE   4  (bases 1 to 5604)
  AUTHORS   Aguado-Fraile E, Ramos E, Saenz-Morales D, Conde E, Blanco-Sanchez
            I, Stamatakis K, del Peso L, Cuppen E, Brune B and Bermejo ML.
  TITLE     miR-127 protects proximal tubule cells against
            ischemia/reperfusion: identification of kinesin family member 3B as
            miR-127 target
  JOURNAL   PLoS One 7 (9), e44305 (2012)
   PUBMED   22962609
  REMARK    GeneRIF: A novel role for miR-127 has been shown in cell adhesion
            and its regulation by HIF-1alpha. KIF3B is identified for the first
            time as a miR-127 target.
REFERENCE   5  (bases 1 to 5604)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 5604)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 5604)
  AUTHORS   Haraguchi K, Hayashi T, Jimbo T, Yamamoto T and Akiyama T.
  TITLE     Role of the kinesin-2 family protein, KIF3, during mitosis
  JOURNAL   J Biol Chem 281 (7), 4094-4099 (2006)
   PUBMED   16298999
REFERENCE   8  (bases 1 to 5604)
  AUTHORS   Fan J and Beck KA.
  TITLE     A role for the spectrin superfamily member Syne-1 and kinesin II in
            cytokinesis
  JOURNAL   J Cell Sci 117 (Pt 4), 619-629 (2004)
   PUBMED   14709720
REFERENCE   9  (bases 1 to 5604)
  AUTHORS   Baker SA, Freeman K, Luby-Phelps K, Pazour GJ and Besharse JC.
  TITLE     IFT20 links kinesin II with a mammalian intraflagellar transport
            complex that is conserved in motile flagella and sensory cilia
  JOURNAL   J Biol Chem 278 (36), 34211-34218 (2003)
   PUBMED   12821668
REFERENCE   10 (bases 1 to 5604)
  AUTHORS   Muresan V, Abramson T, Lyass A, Winter D, Porro E, Hong F,
            Chamberlin NL and Schnapp BJ.
  TITLE     KIF3C and KIF3A form a novel neuronal heteromeric kinesin that
            associates with membrane vesicles
  JOURNAL   Mol Biol Cell 9 (3), 637-652 (1998)
   PUBMED   9487132
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474050.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061386.1, XM_001061444.1, XM_001061322.1, XM_001061504.1,
            XM_215883.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5604
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..5604
                     /gene="Kif3b"
                     /note="kinesin family member 3B"
                     /db_xref="GeneID:296284"
                     /db_xref="RGD:1306815"
     exon            1..77
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            78..1545
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..2385
                     /gene="Kif3b"
                     /EC_number="5.6.1.3"
                     /codon_start=1
                     /product="kinesin-like protein KIF3B"
                     /protein_id="NP_001099999.1"
                     /db_xref="GeneID:296284"
                     /db_xref="RGD:1306815"
                     /translation="MSKLKSSESVRVVVRCRPMNGKEKAAAYDKVVDVDVKLGQVSVK
                     NPKGTSHEMPKTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGK
                     TYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQ
                     TKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAI
                     FVITVECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALG
                     NVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYA
                     NRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGG
                     GEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKM
                     EDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRRERE
                     IQQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKER
                     QELEQTQNELTRELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPITRLENQQ
                     MMKRPVSAVGYKRPLSQHARMSMMIRPEPRYRAENIMLLELDMPSRTTRDYEGPAISP
                     KVQAALDAALQDEDEIQVDASSFESTANRKAKARPKSGRKSGASSSSSGNPASQFYPQ
                     SRGLVPK"
     exon            1546..1647
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1770
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1889
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1890..2003
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2004..2109
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2110..2288
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..5604
                     /gene="Kif3b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctccccat ccggggcagc ggggaatggc tgagcccggg gttcgccgcc gccgcccgct
       61 ctcggctgcg gccgcagaac cttagcatct cgagccattt tggatttgta gccctcaagg
      121 ataagctggt cagagttcat catgtccaag ttaaaaagct cagagtcagt ccgggtggta
      181 gttcgctgtc ggcctatgaa tggcaaggaa aaggctgctg cttatgacaa ggtggtagat
      241 gtggatgtga agctggggca ggtgtctgtg aagaacccca aaggcacatc ccatgagatg
      301 cccaagacct tcacctttga tgctgtatat gattggaacg ccaagcagtt tgaactctat
      361 gatgagacat tccgaccact tgtggactct gtcctgcagg gtttcaatgg cacaattttt
      421 gcctacggac aaacaggaac tgggaaaacc tataccatgg aaggagtccg tggtgaccct
      481 gaaaaaagag gggtcatccc caactccttt gatcacatct tcacccacat ctctcgatcg
      541 cagaatcagc agtatctggt cagggcatct tacttagaga tctatcagga agagatccga
      601 gacttgcttt caaaggatca gaccaaaagg ctggagctca aagagagacc agatacagga
      661 gtgtacgtga aggatttgtc gtcttttgtc accaagagtg tgaaggagat agagcatgtg
      721 atgaatgtgg gaaaccagaa ccggtcggtt ggtgccacca acatgaacga gcatagctcg
      781 cggtcgcatg cgatctttgt catcacggtt gaatgcagcg aggtgggcct ggacggtgaa
      841 aaccacatcc gagtaggaaa actgaacctt gtagatcttg ctggcagtga gcggcaagcc
      901 aagactggag ctcaagggga aagactgaag gaagcgacca agatcaacct gtccctttca
      961 gccttgggta atgttatctc tgcccttgta gatggcaaaa gcacccatat tccatataga
     1021 gactcaaaac tgaccaggct tctccaggat tcccttggtg gcaatgccaa aactgtgatg
     1081 gtagccaatg tggggcctgc ctcttacaat gtagaagaga ccctgaccac tctgagatat
     1141 gccaaccgtg ccaaaaacat taagaacaag ccaagggtca atgaggaccc aaaggatgct
     1201 ctgcttcgtg aattccaaga agaaattgct cggctcaagg cccagctgga aaaacgttcc
     1261 attggcagga ggaagaggcg agagaagcgg agggaaggtg gtggcagtgg tgggggtggg
     1321 gaagaggagg aggaggaggg agaagagggt gaggaggaag gggatgataa ggatgattac
     1381 tggcgggaac agcaagaaaa actggagatt gagaagcggg ccattgtaga ggaccacagc
     1441 ttggttgcag aggagaagat gaggctgctg aaggagaagg agaaaaagat ggaggacctg
     1501 cggcgggaga aggacgctgc tgagatgctg ggtgccaaaa tcaaggccat ggagagtaag
     1561 ctgcttgttg gaggaaaaaa tatagtagat catacaaacg agcagcagaa gatcttggaa
     1621 cagaagcgcc aggagatcgc agagcagaaa cgtcgagaaa gagaaattca gcagcagatg
     1681 gagagtcgag atgaggagac cttggaactg aaagagacgt atacctcatt gcagcaagag
     1741 gtagacatca agaccaaaaa actcaaaaag ctattttcca agcttcaggc tgtgaaggct
     1801 gagatccatg acctccaaga agaacacatc aaagagcgcc aggagctgga gcagacgcag
     1861 aatgagctca ccagagagct aaagctcaag catcttatta tagaaaactt tattcccttg
     1921 gaagagaaga ataaaattat gaatagatcc ttttttgatg atgaagaaga ccattggaaa
     1981 ttacatccta taaccagact ggagaaccag cagatgatga agaggccagt ctctgccgta
     2041 ggatacaaga gaccactgag ccagcatgca cggatgtcca tgatgattcg gccagagccc
     2101 cggtacaggg cagagaacat catgctcttg gagttagata tgcccagccg gacaaccaga
     2161 gactatgagg gcccagcaat ttctcccaag gttcaggctg cactggatgc agctctgcaa
     2221 gatgaggatg agatacaggt ggatgcctct tcctttgaaa gtactgcaaa tagaaaagcc
     2281 aaggccaggc ctaagagtgg caggaaatca ggagcctcct cttcctcctc aggaaaccct
     2341 gcatctcagt tttacccaca gtctcggggg ctggttccca agtaacccag cacccctccc
     2401 agggtgggaa cagcattgtc ttctgagaga aaagcgagca caatactgca gagatgactt
     2461 gagcctaaac acagaaccat tcccctgagg aggagtgatg gcctctttgc agattagcca
     2521 acttaatctt cccgaacatg ctggtcctga tctggcactc agttcctctg ggaagtgtcc
     2581 tttaattagc atctcagaat gcatgggtaa ggtaaaatgc aaagtccaag tggacagcaa
     2641 gaatgaccac gaccttgctt tccttctttc tcccctcccc acttccctcc ctttcctatt
     2701 ctctagcctc ctctacacac cagcctccct ccttgttaaa caatatggag tcgaggcctc
     2761 cttaggactg tgtgtagagc ctcggcctaa agtgatagta gggctgacaa atgaacttga
     2821 ataggtacct gcttctgtca ggtgaaatga gagatctcac ttggaaccaa gcccaggatg
     2881 gcaccatggg cgagcgatcc agcttctggg ccctcagtag gagtagatct gcctggaatc
     2941 cattgaatgg gggtgggagg atgacttcca gttcctgctc cagaaggact tcgtgttgga
     3001 agcaatagaa gagacatttt ctctgcctcc tgggagagtt tggggaaata gcttttttta
     3061 aaatctcaaa accacgacca tcctgttaaa gatctaagtc tataaaccag tgccatgttc
     3121 atctcccatg tcactttact cttcatttgt cacggtcttc cccaagtaca catgctctgt
     3181 gtgagtgggg cgcgtgaaga cccaccagca gagcatgcct atacagtgtg ctttgaggtg
     3241 ggagaaggga agctggctct gccttctctg atgggagtag agttgggaag gcattaggaa
     3301 caggcacttc tgaatccccc atttgggtcc ttaccatcct gggagcagaa gagtgaatag
     3361 gcagttgcgg actaggggca ggagactcag agcggggagg ggagatagag gtggaagcaa
     3421 aggaattgtg tctgcctgga gcagaaaccc actgacaagt gtggctcccc taggtgctgg
     3481 caagaagagg ctctgagtga gcaggctcag agcggagtcc acacttcctg tttacataga
     3541 ctagtttggt ttataagttt tagttttcat gttatggcgc ctcgagcttt ggtttaagtt
     3601 ggtcattagg tgacagttac tcattttccc taagagaaat gcatgagtgt gtggggctgt
     3661 gtgtgcacag tagtctctgt gctctgcgtg tgtctctaag agacactgaa aacccgccca
     3721 gctttagaaa tactccaacg tgcagtgttt gcctttgtct gcattaaagg cccacagaat
     3781 gactaatcca ggctggaagc acgccccatg aagtgtcttg agtccatgat ccaaccctga
     3841 ggggacagtg agtcctcaag tctgccacac tggcgtacct tgctggcatg gtgcctcagg
     3901 aagatggcag ctcaggtggg ccttgagaca tcttttcact cagctgcttg gtctccaggg
     3961 atatttctgg atcagagcct gtgggaagga ggaatagagt ataatgtctt gacattctgt
     4021 atcatggaga tccgtggatc ttcttgtcag cttcctctct gagcccagag ccctattgag
     4081 cagttccttg gatggaatgg aacctatctc atcttttctt ggtctcaaac cctgtttctt
     4141 ccttatgtcc taagaacttg cttgtttgac taggatccaa ataaggagat atgtgctcta
     4201 agatggctgt ttgctggtga tacttgtctc tcttacattt cctcacagct agtctaaatt
     4261 ctgtaggctg acgacatttg tgtaccaaaa caggattgca aacttcaggt aatatcatac
     4321 cttaatactg gtgtcttgaa gtggttaatg tgatagtagc aggggttaag tgacacatag
     4381 aacttttcca agaagacaaa ggaaaaaaat ttggaagaca tgattattaa agcaagcttg
     4441 ccctgtcctc agctgggttc ttacggtggt ctgtggacac caagtagaag gccacctatg
     4501 tggtgatgaa gctgtccctt cccggatagc ctctggtgct tctcttttct caatacggat
     4561 ccgatactga agagagcaga tggtaaaaat gtcttgctgc ccccagaatg ctgctgcttt
     4621 gagttctgag ttgagccaag actatagagg atgcatgaag ctcactgagg gaccagagct
     4681 ttatgctgtc atctgtctgg gatgctggaa ggccacagcc tacagtagcc attgtagttt
     4741 agaagcaagt ctttaaaagg atctaagaag atcgtctggg aggagtttga ggctgcacat
     4801 acaatccttt ttggactctt ttcctctgct cggtagaatg tatctgacat tgtatcagat
     4861 gacacaattt ccagatcctt acagtcagag tcagagtccc caaaccatag gcatgaagca
     4921 ctttcttaag actgacctac gttgaattgc tccctgtctg atgcctgcat gctgcttgaa
     4981 ttgtccacct acatctccat gaccaagggt gccaggatgc agtgcagctc aggcacgggc
     5041 cgctcgtctg ctctccccag ctctcgctaa gtcctccttc accgaatgta gactgccaag
     5101 tttctgagaa gcgccagtcc cctgctaaca tagactatca gttctgcctc actgtgcctc
     5161 ttgagtttga ggggtactat ggtcatcgta gaccatccag acaccatctg tgaatgaaat
     5221 ggggccacca aggcactcca atgaaattgc cataacgaaa acctcagcgg gaactaggtc
     5281 agagcagtta ccgacagtta ccgtgaaagt cctggcctgg tatactcaga ctctagcacc
     5341 ttcctctgcc catctcgtga atgaaacact tctgaggttc ttatggaagg agtgatgtgg
     5401 gcaggcagga ggggggcgcg atggctcttt ggagttacta ttgaccttga ccttctcttc
     5461 ggctgtcttt agataaaggc tatgccagta cttgggactt aagttttaca attgatattt
     5521 atttgtatta tctctttgtc tagcgatgta aaagtgattc taaactaaaa tgtgtaataa
     5581 aatcaatcag atttattgta tgta
//
