LOCUS       NM_145877               4213 bp    mRNA    linear   ROD 17-JUN-2024
DEFINITION  Rattus norvegicus kinesin family member 1C (Kif1c), mRNA.
ACCESSION   NM_145877 XM_346386
VERSION     NM_145877.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4213)
  AUTHORS   Laragione,T., Harris,C. and Gulko,P.S.
  TITLE     KIF1C and new Huntingtin-interacting protein 1 binding proteins
            regulate rheumatoid arthritis fibroblast-like synoviocytes'
            phenotypes
  JOURNAL   Front Immunol 15, 1323410 (2024)
   PUBMED   38726004
  REMARK    GeneRIF: KIF1C and new Huntingtin-interacting protein 1 binding
            proteins regulate rheumatoid arthritis fibroblast-like
            synoviocytes' phenotypes.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4213)
  AUTHORS   Gumy,L.F., Katrukha,E.A., Grigoriev,I., Jaarsma,D., Kapitein,L.C.,
            Akhmanova,A. and Hoogenraad,C.C.
  TITLE     MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus
            KIF5-Dependent Cargo Transport in Sensory Neurons
  JOURNAL   Neuron 94 (2), 347-362 (2017)
   PUBMED   28426968
REFERENCE   3  (bases 1 to 4213)
  AUTHORS   Efimova,N., Grimaldi,A., Bachmann,A., Frye,K., Zhu,X.,
            Feoktistov,A., Straube,A. and Kaverina,I.
  TITLE     Podosome-regulating kinesin KIF1C translocates to the cell
            periphery in a CLASP-dependent manner
  JOURNAL   J Cell Sci 127 (Pt 24), 5179-5188 (2014)
   PUBMED   25344256
  REMARK    GeneRIF: KIF1C translocation to the cell periphery intensifies and
            KIF1C accumulates both in the proximity of peripheral microtubules
            that show enrichment for the plus-tip-associated proteins CLASPs
            and around podosomes.
REFERENCE   4  (bases 1 to 4213)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 4213)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 4213)
  AUTHORS   Moser,K. and White,F.M.
  TITLE     Phosphoproteomic analysis of rat liver by high capacity IMAC and
            LC-MS/MS
  JOURNAL   J Proteome Res 5 (1), 98-104 (2006)
   PUBMED   16396499
REFERENCE   7  (bases 1 to 4213)
  AUTHORS   Nakajima,K., Takei,Y., Tanaka,Y., Nakagawa,T., Nakata,T., Noda,Y.,
            Setou,M. and Hirokawa,N.
  TITLE     Molecular motor KIF1C is not essential for mouse survival and
            motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum
            transport
  JOURNAL   Mol Cell Biol 22 (3), 866-873 (2002)
   PUBMED   11784862
REFERENCE   8  (bases 1 to 4213)
  AUTHORS   Rogers,K.R., Griffin,M. and Brophy,P.J.
  TITLE     The secretory epithelial cells of the choroid plexus employ a novel
            kinesin-related protein
  JOURNAL   Brain Res Mol Brain Res 55 (2), 355 (1998)
   PUBMED   9582454
REFERENCE   9  (bases 1 to 4213)
  AUTHORS   Rogers,K.R., Griffin,M. and Brophy,P.J.
  TITLE     The secretory epithelial cells of the choroid plexus employ a novel
            kinesin-related protein
  JOURNAL   Brain Res Mol Brain Res 51 (1-2), 161-169 (1997)
   PUBMED   9427518
  REMARK    Erratum:[Brain Res Mol Brain Res 1998 Apr;55(2):355]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 26, 2020 this sequence version replaced NM_145877.1.
            
            Sequence Note: Sequence Note: The RefSeq transcript and protein
            were derived from genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ000696.1, SRR21887620.1356993.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-161               JAXUCZ010000010.1  55913093-55913253
            162-267             JAXUCZ010000010.1  55915053-55915158
            268-400             JAXUCZ010000010.1  55915379-55915511
            401-477             JAXUCZ010000010.1  55915902-55915978
            478-657             JAXUCZ010000010.1  55916314-55916493
            658-723             JAXUCZ010000010.1  55917095-55917160
            724-902             JAXUCZ010000010.1  55917523-55917701
            903-1014            JAXUCZ010000010.1  55917794-55917905
            1015-1092           JAXUCZ010000010.1  55918257-55918334
            1093-1158           JAXUCZ010000010.1  55918478-55918543
            1159-1234           JAXUCZ010000010.1  55918633-55918708
            1235-1313           JAXUCZ010000010.1  55919261-55919339
            1314-1459           JAXUCZ010000010.1  55919520-55919665
            1460-1629           JAXUCZ010000010.1  55921239-55921408
            1630-1709           JAXUCZ010000010.1  55921580-55921659
            1710-1785           JAXUCZ010000010.1  55921751-55921826
            1786-1865           JAXUCZ010000010.1  55929656-55929735
            1866-1960           JAXUCZ010000010.1  55931114-55931208
            1961-2044           JAXUCZ010000010.1  55936415-55936498
            2045-2231           JAXUCZ010000010.1  55937416-55937602
            2232-2304           JAXUCZ010000010.1  55937727-55937799
            2305-2919           JAXUCZ010000010.1  55938461-55939075
            2920-4213           JAXUCZ010000010.1  55940927-55942220
FEATURES             Location/Qualifiers
     source          1..4213
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..4213
                     /gene="Kif1c"
                     /note="kinesin family member 1C"
                     /db_xref="GeneID:113886"
                     /db_xref="RGD:70928"
     exon            1..161
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            162..267
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            268..400
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..3597
                     /gene="Kif1c"
                     /note="kinesin-like protein KIF1D; kinesin 1C"
                     /codon_start=1
                     /product="kinesin-like protein KIF1C"
                     /protein_id="NP_665884.2"
                     /db_xref="GeneID:113886"
                     /db_xref="RGD:70928"
                     /translation="MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSK
                     DAPKSFTFDYSYWSHTSVEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAG
                     KSYTMMGRQEPGQQGIVPQLCEDLFSRVNVNQSAQLSYSVEVSYMEIYCERVRDLLNP
                     KSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSH
                     AVFTIVFTQRSHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLT
                     TLGKVISALADLQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEE
                     TLSTLRYADRTKQIRCNAVINEDPNARLIRELQEEVARLRELLMAQGLSASALGGLKV
                     EEGSPGGVLPAASSPPAPASPSSPPPHNGELEPSFSPSAEPQIGPEEAMERLQETEKI
                     IAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDP
                     LMSECLLYHIKDGVTRVGQVDVDIKLTGQFIREQHCLFRSIPQPDGEVMVTLEPCEGA
                     ETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDW
                     NFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGEDSDK
                     RSCEESWRLISSLREQLPPNTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPR
                     WATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPEGPGDAWRA
                     VARDVWDTVGEEEGCGGGGGGGEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRE
                     LQALRDRMLRMERVIPLTQDLEDDNEESGLVTWAPPEGSEAVEEAVSNDHSPAVRPSS
                     PPQSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPH
                     DCKLRFPFKSNPQHRESWPGMGSGEAPGPQPPEEVTAPPPPPNRRPPSPRRPHRPRRN
                     SLDGGSRSRGGGSTQPEPQHLRPQKHNSYPQQPQPYPAQRPGPRYPPYTTPPRMRRQR
                     SAPDLKESGAAV"
     exon            401..477
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            478..657
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            658..723
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            724..902
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            903..1014
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1092
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1158
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1234
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1313
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1459
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1629
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1709
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..1785
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..1865
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1960
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2044
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2231
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2304
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            2305..2919
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
     exon            2920..4213
                     /gene="Kif1c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttctgctgcc gcccccgggg cgcgatccgc cgcccgccgc ccggggaccc ggcgaggggc
       61 gggggcagcc ccgaactggc cccaggtctc tccctagccg gtcatagaca tcccagaaag
      121 tttgtccctt tgctctctgc cgggagtcct gccgcgagga gccttgctgg tgtggccagg
      181 ccccaagtgt aggatggggc ttcccatacg agggccggtg gcagccagaa ctgatacagc
      241 cccgctgatc tggggccagg acaccagctg aggagggcag gagattctga agctatggct
      301 ggtgcctccg tgaaagtggc agtgagggtt cggcccttta atgcccgtga gaccagccag
      361 gatgccaagt gtgtggtcag catgcagggc aacaccacct ccatcattaa tcccaaacag
      421 agcaaggatg cccccaaaag cttcaccttc gactattctt actggtcaca tacttcggtg
      481 gaggacccac agtttgcatc tcaacagcag gtgtatcgag acataggaga ggagatgctg
      541 ctgcatgcct ttgaaggcta caacgtgtgc atctttgcct acgggcagac gggggctggc
      601 aagtcctaca ccatgatggg gcggcaggaa ccggggcagc agggcattgt acctcagctc
      661 tgcgaggacc tcttctctcg agttaatgtg aaccagagtg ctcaactttc ctactctgtg
      721 gaggtgagct atatggagat ctattgcgaa cgagtacgag acctcttgaa ccccaagagt
      781 cggggctctc tgcgggtccg ggagcacccc atcctgggcc catatgtaca agacctgtct
      841 aagttggctg tgacttccta tgcagacatt gctgacctca tggactgtgg aaataaggca
      901 agaactgtgg ctgccaccaa catgaacgaa accagcagcc gctcccacgc tgtctttact
      961 atcgtcttta cccagcgctc ccatgaccag cttactggac tggattcaga aaaggtcagt
     1021 aagatcagct tggtggacct tgccgggagc gagcgggccg actcctcagg ggctcggggc
     1081 atgcgtctga aggaaggtgc aaacatcaat aagtccctga ctactctagg gaaggtgatc
     1141 tcagccctgg cagatttgca atcaaagaag cggaagtcgg acttcatccc ttacagagac
     1201 tctgtgctta cctggctact caaggagaat ttgggtggga actcacgcac agcaatgatt
     1261 gcagccctga gtcccgctga catcaattac gaggagacac tcagcactct caggtacgca
     1321 gaccgcacca aacagatccg atgcaatgct gtcatcaatg aggaccccaa tgcccggctt
     1381 atccgggagc tgcaggagga ggtggcccgg ttgcgggaac tgctgatggc tcaggggctt
     1441 tcagcctctg ctctaggagg tctaaaggtg gaagagggga gtcctggagg tgttctgcct
     1501 gctgcatcat ctccccctgc cccagcttca ccctcatctc ctcctccaca taacggcgag
     1561 ctggagccgt cattttcacc cagtgctgag ccccagattg ggcctgagga ggccatggag
     1621 aggctgcagg aaacagagaa aattatagct gagctgaatg agacttggga ggagaagctc
     1681 cgtaagacag aagctctgag gatggagaga gaagcattgc tggctgagat gggcgtggcc
     1741 gtccgggagg atggcggtac tgtgggtgtc ttctctccaa aaaagactcc ccacctggta
     1801 aatctgaatg aggacccctt gatgtctgaa tgccttctct accacatcaa agatggcgtc
     1861 accagggttg gccaggtaga tgtggacatc aagttgactg gccagttcat ccgggagcag
     1921 cactgcctct tccgcagcat ccctcagcct gatggagaag tgatggtcac attggaacct
     1981 tgtgaaggag ctgagacata tgtcaatggg aagcttgtga cggagccgct ggtgctgaag
     2041 tcaggcaaca ggattgtaat gggcaagaac catgtgttcc gcttcaatca cccggagcaa
     2101 gcacggctgg aacgagagcg aggggtcccc ccacccccag gacctccctc tgagcctgtg
     2161 gactggaact ttgctcagaa ggagctgctg gagcagcaag gcatagacat caagctagag
     2221 atggagaaga ggctacaaga cttggagaat cagtaccgga aagaaaagga agaggctgac
     2281 cttttgctgg agcagcagcg gctgtatgca gattctgaca gtggggaaga ctctgacaag
     2341 cgctcttgtg aagaaagctg gcggctgatt tcctccttgc gggagcagct gccccctaac
     2401 acagtccaga ccatcgtcaa gcgctgtggc ctgcccagca gtgggaagcg cagggcccct
     2461 cgaagagttt accagatccc tcagcgacgg cggctccagg gcaaagaccc ccggtgggcc
     2521 accatggctg acctgaagat gcaagcagtg aaggagatct gctatgaggt ggccctggcc
     2581 gacttccgtc acggacgggc agagattgaa gctctggctg ctctcaagat gagggagctg
     2641 tgccggacct acggcaagcc tgagggtcct ggagacgcct ggagagctgt ggccagggat
     2701 gtctgggata ctgtgggtga agaagaagga tgtggaggtg gtggaggtgg tggtgaggaa
     2761 ggagcccgtg gggcagaggt agaagacctc cgggctcata ttgacaagct gacaggaatt
     2821 ctgcaggaag tgaagctgca aaacagcagc aaggaccggg agctgcaggc cctgcgggac
     2881 cggatgctcc gcatggagag ggttatcccg ttgacccagg atcttgagga tgataatgaa
     2941 gaatctggtt tggtcacctg ggccccaccc gaagggtcag aggcagtaga ggaggcagtg
     3001 tccaatgacc actcaccagc tgtccggccc tcctcaccac cccagtccag ctgggagcgt
     3061 gtgtcaagac tgatggaaga ggaccctgcc ttccgtcgcg gtcgccttcg ctggctcaag
     3121 caggagcagc tgcggctgca gggactgcag ggctccgggg gccggggtgg gggactacgc
     3181 aggcctccag ctcgctttgt acccccgcat gattgcaagc tgcgcttccc cttcaagagc
     3241 aaccctcagc acagggagtc ctggccagga atggggagtg gtgaggcccc aggtccccaa
     3301 ccccctgaag aggtcactgc accccctcct ccccctaacc gcagacctcc aagtccccga
     3361 aggccccacc gtcctcgcag gaattcccta gatggaggga gccgatctcg gggagggggt
     3421 tctacacagc cagaacccca gcacttacgg ccccagaagc acaactctta tccccaacag
     3481 ccccaacctt acccagccca gcggccaggg ccccgctacc caccatacac tacccctcca
     3541 cgaatgcgaa ggcagcgctc agcccctgac ctcaaagaga gtggggcggc tgtgtgagtc
     3601 ccacgctggg cagacagggc ctagtggggc ccttgctagg agaaaggtgc ccgctgcttc
     3661 cccaagaagc ccgtggcagg gagaccagaa agcagagagc aagagagagg gaaggtccga
     3721 gtaggtggta gaagatgctg agagagagct ggaggctgag ggaaggaaga gggcgcggag
     3781 ttgccaggag caaaccaaag tcagggaaga accataggaa gttgtcttgg ggctacccgt
     3841 ttcagggggg agtcccacaa acgctgctat gggtgggtgg gtgggctggg gtctgcatag
     3901 ccagtgtttg actttctttt tgagtggatg caacggggag agaaccaaga gtgaggtggg
     3961 ttctcctccc cggctcttgt ccgtccgtct gtccgtctgt ctgtggtgga gttctgtttc
     4021 cagggtggtg tggtgggatc ctaagtcatt cccttcccct tccaggcctc ctgctatatt
     4081 taggggacct gtctggtttg gctggagtcc cgcaagaatg tgggacctct taataaagga
     4141 tagcaaacag cttgtggctg gctgggtttt agtagaggtt caggttgtgc gagtaaagtg
     4201 tatcatcgtt tta
//
